Clinical trials: Arthroplasty
Knee Osteoarthritis, Total Knee Arthroplasty
Improvement of Total Knee Arthroplasty Effectiveness Using Preoperative Prehabilitation
Total knee arthroplasty (TKA) is the most effective treatment for stage III-IV knee osteoarthritis (OA). However, up to 30% of patients remain dissatisfied due to periarticular functional insufficiency, pain, and movement…
- Trial name
- TKA-PREHAB (NCT07790146)
- Testing
- Multimodal phenotype-based prehabilitation
- Where
- Russia
- Volunteers
- 64 people
- Sponsor
- Samara State Medical University
Proximal Humerus Surgery, Rotator Cuff Surgery
Effect of Liposomal Bupivacaine and Bupivacaine Hydrochloride for Superior Trunk Block of the Interscalene Brachial Plexus on Postoperative Diaphragmatic Function and Analgesia
To compare the effects of 1.33% liposomal bupivacaine versus 0.375% bupivacaine hydrochloride for superior trunk block of the interscalene brachial plexus on postoperative diaphragmatic function and analgesic efficacy in shoulder…
- Conditions
- Proximal Humerus Surgery, Rotator Cuff Surgery, Shoulder Arthroplasty, Shoulder Arthroscopy
- Trial name
- NCT07587203
- Testing
- Liposomal bupivacaine, Bupivacaine Hydrochloride
- Where
- 3 sites in China
- Volunteers
- 184 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Total Knee Arthroplasty
interACTION: A Portable Joint Function Monitoring and Training System for Remote Rehabilitation Following TKA
The purpose of this study is to determine if home-based therapy with monitoring via telemedicine can overcome many barriers to compliance and improve rehabilitation.
- Trial name
- NCT02646761
- Testing
- InterACTION, Standard of Care Physical Therapy
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- James J. Irrgang
Osteoarthrosis, ERAS
Nursing Intervention for the Reduction of Anxiety During the Process of Primary Total Hip Arthroplasty Within the Optimized Recovery Program.
Osteoarthrosis (OA) is a chronic, degenerative disease characterized by joint wear and tear. It is a major cause of pain, disability and decreased quality of life.
- Conditions
- Osteoarthrosis, ERAS, Anxiety, Nurse
- Trial name
- NIRARATC (NCT05882227)
- Testing
- video, Traditional information
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- University of Barcelona
Total Knee Arthroplasty (TKA)
Total Knee Arthroplasty Biomechanics
In total knee arthroplasty (TKA), the relationship between implant design, soft tissue balance, neuromuscular contributions, and rehabilitation strategies on patient satisfaction and functional outcomes is highly complex and…
- Trial name
- NCT03671954
- Testing
- Home Strengthening Exercises, Standard Physical Therapy, Preoperative Assessments
- Where
- 4 sites in United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Florida
Arthroplasty, Replacement, Knee, Robotics
Comparison of Ambulatory and Functional Improvement by Morning Walk
The aim of this study is to determine the clinical efficacy and feasability of gait rehabilitation robot through approving functional improvement by an end-effector typed gait robot in patients underwent total knee arthroplasty.
- Trial name
- NCT03183856
- Testing
- Morning walk, no Morning walk
- Where
- South Korea
- Volunteers
- 9 people
- Sponsor
- Ulsan University Hospital
Total Knee Anthroplasty, Venous Insufficiency (Chronic)(Peripheral)
Impact of Chronic Venous Insufficiency on Outcomes After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is an effective treatment for end-stage knee osteoarthritis; however, postoperative complications-particularly wound healing problems-remain a significant concern.
- Conditions
- Total Knee Anthroplasty, Venous Insufficiency (Chronic)(Peripheral), Doppler Ultrasound Diagnosis
- Trial name
- VENOUS-TKA (NCT07577141)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- SB Istanbul Education and Research Hospital
Knee Arthropathy, Telerehabilitation
Core Stability Via Telerehabitation on TKA
Objective: To investigate the effects of core stability exercises (CSE) added to the standard exercises (SE) on patient-reported (PR) and performance-based (PB) outcomes in patients with total knee arthroplasty (TKA) followed…
- Trial name
- NCT06159205
- Testing
- standard exercises, core stability exercises
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
Postoperative Pain
Low Dose Ketamine Infusion for Postoperative Analgesia After Total Knee Arthroplasty
This study evaluates continous infusion of low-dose ketamine during intraoperative and postoperative periods at three different doses to provide postoperative analgesia in total knee arthroplasty cases.
- Trial name
- NCT04085588
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Mustafa Kemal University
Arthroplasty Complications
Early Clinical and Radiological Outcomes of Uncemented Fully Coated Stem With Patients of 85 Years and More, Complications and Risks Factor
Retrospective, single-centre study. Review of patients aged 85 and over who underwent total hip replacement between June 2015 and February 2022.
- Trial name
- NCT05969366
- Testing
- Total hip arthroplasty
- Where
- France
- Volunteers
- 79 people
- Sponsor
- Central Hospital, Nancy, France
Knee Osteoarthritis
Unicondylar- or Total Knee Replacement? Patient Satisfaction, Function and Muscle Mass
Patients with medial gonarthritis are randomised to a unicompartmental or a total knee replacement. Primary outcome: Thigh muscle cross sectional area and radiological attenuation measured by CT Secondary aims: functional tests…
- Trial name
- UKA or TKA? (NCT02563756)
- Testing
- Unicompartmental knee replacement, Total knee replacement
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Osteoarthritis, Hip, Rheumatoid Arthritis
Exception Cementless Hip Stem
This study is a multicenter, retrospective and prospective, non-controlled, non-randomized post market clinical follow-up study.
- Conditions
- Osteoarthritis, Hip, Rheumatoid Arthritis, Inflammatory Arthritis, Congenital Hip Dysplasia
- Trial name
- Exception (NCT04349046)
- Testing
- Total hip arthoplasty (THA)
- Where
- 6 sites in Belgium, France
- Volunteers
- 332 people
- Sponsor
- Zimmer Biomet
Prevention of Venous Thrombosis After TKA
Clinical Study on the Efficacy and Safety of Multiple Oral Administrations of SHR2285 Tablets in Patients Undergoing Elective Total Knee Arthroplasty
This study is a multi-center, randomized, open-label, double-blind, positive-controlled phase II clinical study evaluating the efficacy and safety of different doses of SHR2285 tablets vs.
- Trial name
- NCT05203705
- Testing
- SHR2285 tablet, Enoxaparin
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Shanghai Hengrui Pharmaceutical Co., Ltd.
Hip Arthroplasty
Rehabilitation to Patients Over 65 Years Undergoing THA
Patients over 65 years do not have a self care ability the surgery benefits them. The aim of this study is development of a rehabilitation program based on patients' self-rated health. 1.
- Trial name
- NCT00226070
- Testing
- interview and advising, 3 follow up interviews and personal advising, interview SF-36 self rated health
- Where
- 6 sites in Denmark
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Osteoarthritis
The Subvastus Approach in Total Knee Arthroplasty
The purpose of this study is to determine if the observed benefits of minimally invasive total knee arthroplasty, namely decreased hospital stay and increased range of motion, can be achieved with standard knee arthroplasty using…
- Trial name
- NCT00346788
- Testing
- Surgical approach for total knee arthroplasty
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- Nova Scotia Health Authority
Shoulder Disease
Short-Term Outcomes of Total Shoulder Arthroplasty Using the Titan Modular Total Shoulder System
The goals of total, reverse total and hemi shoulder arthroplasty are the same, to alleviate the patient's pain and obtain a full functional recovery.
- Trial name
- NCT03956316
- Testing
- Titan Modular Total Shoulder System
- Volunteers
- 25 people
- Sponsor
- OrthoIndy
Osteoarthritis, Knee
Efficacy and Safety of NAVIO
The goal of the study is to compare the efficacy, safety and costs of the NAVIO™ system with the conventional intramedullary alignment guide for total knee replacement in a clinical setting.
- Trial name
- NCT04230616
- Testing
- total knee arthroplasty, CT scan
- Where
- Belgium
- Volunteers
- 180 people
- Sponsor
- Sint-Trudo Hospital
Osteoarthritis
A Multicentre Trial to Compare Two Articulating Bearing Surfaces as Used in Cementless Primary Hip Arthroplasty
The aim of this study is to demonstrate the non-inferiority of the ceramic-on-metal articulation using large diameter bearings (38mm to 60mm) compared to the metal on metal articulation using the same cup in regards to the…
- Trial name
- MagnumCRCT (NCT01247038)
- Testing
- Metal on ceramic articulation, Metal-on-Metal
- Where
- 2 sites in Bosnia and Herzegovina, South Africa
- Volunteers
- 130 people
- Sponsor
- Zimmer Biomet
Hip Osteoarthritis, Avascular Necrosis of Femur Head
Influence of Antiseptic Washes on Wound Healing Complications After THA
The purpose of this research trial is to evaluate the effect of two types of washing solutions on wound healing after total hip replacement surgery.
- Trial name
- NCT07104084
- Testing
- lavage chlorhexidine, lavage povidone-iodine
- Where
- 2 sites in United States
- Volunteers
- 420 people
- Sponsor
- F. Johannes Plate
Ankle Injuries, Femoral Neck Fractures
Clinical Use of Andante SmartStep System in Gait Rehabilitation
The purpose of this study is to evaluate the effectiveness of the biofeedback gait training device in improving load bearing over an operated limb, during post-operative gait training therapy.
- Trial name
- NCT00268658
- Testing
- SmartStep(tm) biofeedback device
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Soroka University Medical Center
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