Clinical trials: Arthroplasty
Total Knee Arthroplasty, Adductor Canal Block
Analgesic Efficacy of Adding SCB With Low Concentration Bupivacaine Combined With Dexamethasone on Pain After TKA
This study evaluate the efficacy of adding popliteal sciatic nerve block with low concentration bupivacaine and dexamethasone to abductor canal block for total knee arthroplasty in patient with NSAIDs prescribing precaution.
- Conditions
- Total Knee Arthroplasty, Adductor Canal Block, Sciatic Nerve Block
- Trial name
- NCT03486548
- Testing
- bupivacaine and dexamethasone, bupivacaine and lidocaine, Ultrasound
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Mahidol University
Knee Osteoarthritis
The Bone Cement Penetration in Medial Fixed-bearing Unicompartmental Knee Arthroplasty
During Medial Fixed-bearing Unicompartmental Knee Arthroplasty, pulsed lavage combined with moderate pressurization achieves deeper cement penetration into cancellous bone than manual rinsing, optimizing the bone-cement-implant…
- Trial name
- NCT07866378
- Testing
- unicompartmental knee arthroplasty
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Tianjin Union Medical Center
Osteoarthritis, Knee, Psychological Disorder
Total Knee Arthroplasty Combined With Psychological Intervention for Patients With Psychological Disorders
Objective To evaluate the incidence of psychological problems in total knee arthroplasty (TKA) patients and examine whether perioperative psychological intervention can improve the outcomes of and patient satisfaction with TKA.
- Conditions
- Osteoarthritis, Knee, Psychological Disorder, Psychological Intervention, Satisfaction
- Trial name
- NCT03715608
- Testing
- Psychological Intervention
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Total Joint Arthroplasty
Non-invasive Hemoglobin Monitoring in Outpatient Total Joint Arthroplasty
This research is being done to better understand the accuracy of noninvasive hemoglobin tests on patients that recently underwent total joint arthroplasty.
- Trial name
- NCT05369325
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Total Knee Arthroplasty, Osteoarthritis
Kinematic and Mechanical Alignment Randomized Trial
Knee replacement surgery is the second most common surgery in Canada. People who have very painful knee arthritis usually receive a knee replacement where the surgeon aims to make everyone's knee as straight as possible (called…
- Trial name
- KMART (NCT06787417)
- Testing
- Restricted Kinematically-aligned Arthroplasty, Mechanically-Aligned Arthroplasty
- Where
- Canada
- Volunteers
- 260 people
- Sponsor
- McMaster University
Lumbar Spinal Stenosis
A Pivotal Study of a Facet Replacement System to Treat Spinal Stenosis
The purpose of this study is to determine if the ACADIA® Facet Replacement System is effective in the treatment of spinal stenosis.
- Trial name
- NCT00401518
- Testing
- Non-randomized ACADIA® Facet Replacement System, Randomized ACADIA® Facet Replacement System, Randomized Instrumented posterolateral fusion (PLF)
- Where
- 29 sites in United States, Puerto Rico
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Globus Medical Inc
Pain (Visceral, Somatic, or Neuropathic), Hip Arthroplasty Replacement
Characteristics of Persistent Pain Composition Following Total Hip or Knee Arthroplasty: a Descriptive Study
Despite high success rates of hip and knee arthroplasty, up to 20% of patients report moderate-to-severe pain (NRS > 3) persisting beyond the expected healing period.
- Conditions
- Pain (Visceral, Somatic, or Neuropathic), Hip Arthroplasty Replacement, Knee Arthroplasty, Total, Survey and Questionnaire
- Trial name
- PAIN-COMPO (NCT07110324)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hip Arthroplasty, Knee Arthroplasty
Operative Hemodynamic Optimization Using the Plethysmographic Variability Index During Orthopedic Surgery
The purpose of this study is to determine whether an operative hemodynamic optimization using the plethysmographic variability index during orthopedic surgery could decrease the length of hospital stay and the postoperative…
- Conditions
- Hip Arthroplasty, Knee Arthroplasty, General Anesthesia
- Trial name
- OPVI (NCT02207296)
- Testing
- Plethysmographic variability index
- Where
- France
- Volunteers
- 440 people
- Sponsor
- University Hospital, Caen
Osteo Arthritis Knee, Total Knee Arthroplasty
Comparing Surgical and Economical Parameters of Total Knee Replacement.
Randomized study comparing surgical and economic parameter of Total Knee Arthroplasty performed using two different specific surgical techniques.
- Trial name
- NCT03427047
- Testing
- MyKnee with single use Efficiency Instrument, Stryker Navigational with conventional metal instruments
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Osteoarthritis, Knee
Effects of Duloxetine on Postoperative Wound Complication of Total Knee Arthroplasty (TKA) in Central Sensitization Patients
Postoperative wound complications such as wound dehiscence, skin necrosis, persistent wound drainage, delayed healing, and superficial skin infection could have devastating consequences, leading to arthroplasty failure and…
- Trial name
- NCT03880916
- Testing
- Duloxetine
- Volunteers
- 80 people
- Sponsor
- The Catholic University of Korea
Arthritis, Degenerative
Pilot Study Evaluating the Safety and Efficacy of a New Hard-on-Hard Total Hip Replacement System
The purpose of this study is to assess the early and long term safety and efficacy of the hard-on-hard total hip replacement system (R3 ODH-ODH utilization) in patients with non-inflammatory arthritis.
- Trial name
- NCT02154516
- Testing
- ODH Hip System
- Where
- 2 sites in South Africa
- Volunteers
- 26 people
- Sponsor
- Smith & Nephew, Inc.
Avascular Necrosis of Hip, Osteoarthritis, Hip
Allofit® IT Ceramic Bearing System in Total Hip Arthroplasty
This is a multi-center, prospective, non-controlled post market surveillance study. The objectives of this study are to obtain survival and outcome data on the Allofit IT Shell in combination with the BIOLOX® delta Taper Liner…
- Conditions
- Avascular Necrosis of Hip, Osteoarthritis, Hip, Inflammatory Arthritis, Post-Traumatic Osteoarthritis of Hip
- Trial name
- NCT03672916
- Where
- 4 sites in Germany, Sweden
- Volunteers
- 185 people
- Sponsor
- Zimmer Biomet
Hip Disease, Hip Fractures
Observational Study Conducted on Patients Receiving the ESOP 2 Stem to Confirm Security and Performance of the Device
This study is a post-market clinical follow-up conducted in order to collect long-term data on security and performance of the ESOP 2 stem, which is intended to be implanted in case of total hip replacement, when used in real…
- Trial name
- ESOP2 (NCT04193163)
- Testing
- Hip prosthesis - ESOP 2 cementless femoral stem
- Where
- 7 sites in France
- Volunteers
- 10 people
- Sponsor
- FH ORTHO
Knee Osteoarthritis, Total Knee Replacement
Movement Dynamics of Knee Osteoarthritis and Total Knee Replacement
This research aims to explore differences in walking and functional movement mechanics, exercise response, and physical activity between people with osteoarthritis (OA), those who have undergone total joint replacement, and…
- Trial name
- MDOA&TKR (NCT06829433)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Portsmouth
Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting
The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty
This study aims to investigate the effects of preoperative white noise and pink noise interventions on sleep quality, anxiety, postoperative pain, nausea, and physiological parameters in patients undergoing elective total hip…
- Conditions
- Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting, Anxiety, Postoperative Pain After Arthroscopic Knee Surgery
- Trial name
- NCT07858058
- Testing
- White Noise Intervention, Pink Noise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ataturk University
Arthroplasty, Replacement, Hip
Promotion and Support for Physical Activity Maintenance Post Total Hip Arthroplasty
Total hip arthroplasty (THA) is considered an efficacious procedure for relieving pain and disability in patients with hip osteoarthritis.
- Trial name
- PANORAMA (NCT04471532)
- Testing
- Behavior change intervention
- Where
- Denmark
- Volunteers
- 192 people
- Sponsor
- Bispebjerg Hospital
Total Joint Arthroplasty
Total Joint Arthroplasty in a Pediatric Population
The primary purpose of this study is to examine the functional ability and quality of life in those patients who received a total joint arthroplasty (TJA) for reasons other than having a solid tumor at the location of the joint.
- Trial name
- NCT04294693
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Colorado, Denver
Unilateral Primary Osteoarthritis of Knee
Bone Mineral Density Changes Under Two Tibial Components in Total Knee Arthroplasty
Osteoarthritis is a progressive disease afflicting to two thirds of Americans. Today, an estimated 43 million individuals have arthritis. By 2020, more than 59.4 million Americans will be affected by the disease.
- Trial name
- NCT01764984
- Testing
- Total knee arthroplasty
- Where
- 3 sites in Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Knee Arthroplasty
Patient Understanding and Satisfaction in Informed Consent for Total Knee Arthroplasty
A structured consent process, in combination with one or a number of the aforementioned modalities (nursing education, handout, video, etc), may reasonably be expected to improve surgical informed consent.
- Trial name
- NCT01582984
- Testing
- video or education session in addition to standard consent
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- jasvinder singh
Osteoarthritis, Vitamin D Deficiency
Preoperative Correction of Vitamin D Deficiency in Total Joint Arthroplasty (TJA)
The purpose of this study is being conducted to determine whether correcting low levels of vitamin D with a single high-dose supplement reduces complications after the participant's primary TJA.
- Trial name
- NCT07006714
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Miami
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