Clinical trials: Arthroplasty
Coxarthrosis; Primary
Ceramic Modular Dual Mobility in Primary Total Hip Arthroplasty (THA)
A randomized controlled trial comparing modular dual mobility inserts with ceramic multilayer coating versus standard polyethylene inserts for primary THA in a cementless acetabular cup
- Trial name
- CeMoD-prime (NCT05547984)
- Testing
- Dual Mobility Cup, Standard Acetabular component
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Aesculap AG
Heterotopic Ossification, Hip Arthropathy
Comparative Analysis of Radiotherapeutic and Medical Procedures for the Prophylaxis of Heterotopic Ossifications
Aim of this study is to proof the efficacy of in Jena established prophylaxis of new bone formation aside the skeleton with irradiation and compare it with the common literature.
- Conditions
- Heterotopic Ossification, Hip Arthropathy, Myositis Ossificans Traumatica, Thigh
- Trial name
- CONFIDENTIAL (NCT06251349)
- Testing
- Radiation, Diclofenac
- Where
- Germany
- Volunteers
- 512 people
- Sponsor
- University of Jena
Tricompartmental Gonarthrosis
Sub-Vastus Versus Mid-Vastus Arthrotomy for Total Knee Arthroplasty: a Randomized Clinical Trial
Randomized, single-blind trial in which one group of patients will be operated with a "Mid-Vastus approach" of the knee joint and the other group will undergo knee surgery with a "Sub-Vastus approach".
- Trial name
- NCT00925626
- Testing
- Sub-Vastus arthrotomy, Mid - Vastus arthrotomy
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Knee Arthroplasty
Functional Performance of the Journey Deuce Bicompartmental Versus the Genesis II Total Knee System
The objectives of this study are to assess the safety and effectiveness of the Journey Deuce Bicompartmental Knee System at 4-6 weeks, 4 months, 1 year, and 2 years when compared to total knee replacement using the Genesis II…
- Trial name
- Deuce (NCT01140815)
- Testing
- Total Knee Replacement, Deuce
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Anderson Orthopaedic Research Institute
Tensor Fasciae Latae Syndrome, Arthroplasty Complications
Does Vessel-sparing Surgery in Anterior Approach Total Hip Arthroplasty Change Clinical Outcome?
During direct anterior approach (DAA) for total hip arthroplasty (THA), ligation of the lateral femoral circumflex artery and vessel is always conducted.
- Trial name
- USP (NCT06308965)
- Testing
- Vessel sparing technique, Vessel ligation technique
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Ziekenhuis Oost-Limburg
Total Knee Arthroplasty, Total Knee Arthroplasty Recovery
Femoral Triangle Block vs Adductor Canal Block on Early Quadriceps Function After Total Knee Arthroplasty
The goal of this clinical trial is to compare the effects of femoral triangle block (FTB) and adductor canal block (ACB) on early quadriceps function after total knee arthroplasty (TKA).
- Conditions
- Total Knee Arthroplasty, Total Knee Arthroplasty Recovery, Total Knee Arthroplasty Postoperative Pain
- Trial name
- NCT07524387
- Testing
- Femoral Triangle Block (FTB) Group, Adductor Canal Block (ACB) Group
- Where
- Japan
- Volunteers
- 136 people
- Sponsor
- Social Medical Corporation Daiyukai
Rotator Cuff Tear Arthropathy
Impact of Humeral Component Version on Outcomes Following RTSA
The proposed study is a prospective, single-blinded, randomized trial to investigate the impact of humeral component version on shoulder range of motion and patient reported functional outcomes following reverse total shoulder…
- Trial name
- NCT03111147
- Testing
- 0 degrees humeral component version, 30 degrees humeral component retroversion
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Corewell Health East
Primary Total Knee Arthroplasty, Intraosseous Morphine Injection
Effectiveness of Adding Morphine to Intraosseous Vancomycin for Pain Control in Total Knee Arthroplasty
Study investigators propose to investigate if a bony injection of pain medication during a knee replacement will help pain levels following primary knee replacement surgery. To investigate this, 86 patients will be enrolled.
- Conditions
- Primary Total Knee Arthroplasty, Intraosseous Morphine Injection, Knee Osteoarthritis
- Trial name
- NCT06716749
- Testing
- Morphine, Vancomycin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Carilion Clinic
Hip Arthropathy
Optimized MRI of Patients With Hip Arthroplasty
This is a single-center single-arm clinical trial with a paired design which compares the effectiveness of 3T MRI with (modified) and without (standard) radiofrequency pulse polarization optimization in reducing metal-related…
- Trial name
- NCT04875884
- Testing
- Modified MRI
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- NYU Langone Health
Osteoarthritis
The Clinical Effect of Pregabalin on Neuropathic Pain in Central Sensitized Patients After Total Knee Arthroplasty
In this study, patients scheduled to undergo total knee arthroplasty (TKA) will be screened through a survey for patients with central sensitivity and patients with neuropathic pain as preoperative evaluation.
- Trial name
- NCT05254652
- Testing
- Duloxetine 30mg, Pregabalin 150mg
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- The Catholic University of Korea
Anesthesia
Evaluation of the Effectiveness of an Accelerated Rehabilitation Protocol Based on Multimodal Analgesia Optimization for Uni-compartmental Knee Prosthesis Surgery
Today, prosthetic replacement for osteoarthritis of the knee is a frequent surgery. In France, nearly 100,000 knee arthroplasties are performed each year .
- Trial name
- APUC (NCT04916158)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Brest
Analgesia, Pain, Postoperative
Comparison Between Perineural and Systemic Effect of Dexamethasone as an Adjuvant for Prolongation of Four Nerve Blocks With Bupivacaine in Total Knee Arthroplasty
The addition of dexamethasone (DxaM) to local anesthetic may significantly prolong the duration of a block in total knee arthroplasty. The aim of this study is to determine whether this is a systemic or local effect.
- Trial name
- NCT02253784
- Testing
- Dexamethasone, Bupivacaine
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Hillel Yaffe Medical Center
Knee Arthritis, Hip Arthritis
Preoperative Pain Threshold and Rapid Recover Programs
To investigate the association between grip strength and preoperative pain threshold as measured by pressure algometer and validated pain outcome surveys.
- Trial name
- NCT02740738
- Testing
- Wagner Pain Algometer, Dynamometer
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Duke University
Arthroplasty, Replacement, Knee
Evaluation of Triathlon - A New Total Knee Prosthesis System - Triathlon PA vs. Triathlon Pressfit
The objective is to investigate the Clinical, Radiographic, Roentgen Stereophotogrammetric behaviour and patient outcome when using the Triathlon total knee prosthesis in a prospective randomized clinical trial.
- Trial name
- TriathlonRSA (NCT03198533)
- Testing
- Triathlon PA, Triathlon Pressfit
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Stryker Orthopaedics
Hypotension, Spinal Anesthesia
Midodrine for Prophylaxis Against Post Spinal Hypotension in Elderly Population
Hip fracture is a common and serious healthcare problem which commonly affects elderly populations. The common route of anesthesia for hip arthroplasty is spinal anesthesia.
- Conditions
- Hypotension, Spinal Anesthesia, Elderly
- Trial name
- NCT05548985
- Testing
- Midodrine Oral Tablet, Metoclopramide
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Cairo University
Knee Osteoarthritis, Total Knee Replacement
Knee Arthroplasty Activity Trial
Total knee replacement (TKR) is a common and costly procedure widely used to relieve pain and improve function in patients with symptomatic advanced knee osteoarthritis (OA).
- Trial name
- KArAT (NCT04107649)
- Testing
- Telephonic Active Coaching (Motivational Interviewing) + Financial Incentives, Wrist based activity tracker wear, Basic Study Activities
- Where
- 5 sites in United States
- Volunteers
- 600 people
- Sponsor
- Brigham and Women's Hospital
Primary Knee Arthroplasty
ATTUNE® Revision- Complex Primary in Total Knee Arthroplasty Population
Five-year, Prospective, multi-center, non-randomized, non-controlled study of the ATTUNE® Revision total knee prostheses, utilizing the fixed bearing (FB) and rotating platform (RP) tibial component with the posterior stabilizing…
- Trial name
- NCT03153449
- Testing
- ATTUNE Revision Knee System in Total Knee Arthroplasty
- Where
- 34 sites in United States, Australia and 8 more
- Volunteers
- 400 people
- Sponsor
- DePuy Orthopaedics
Hip and Knee Osteoarthritis
Recovery After Fast Track THA / TKA
The development and implementation of "fast-track" principles in total knee and hip arthroplasty have resulted in early recovery and rehabilitation alongside a reduced length of hospital stay.
- Trial name
- 0-21 (NCT02137655)
- Where
- 2 sites in Denmark
- Volunteers
- 112 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Exercise
Elastic Band Exercise on the Pain, Kinesiophobia, Functional, and Psychological Status
Aiming to determine the effects of elastic band exercise on kinesiophobia, functional capacity, and depression after the total knee arthroplasty, the present study was designed and carried out as a randomized controlled trial…
- Trial name
- NCT04981106
- Testing
- Elastic Band Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Aksaray University
Femur Neck Fracture, Hip Fractures
Lumbar Erector Spinae Plane Block Versus PENG Block for Hip Fracture Surgery
The purpose of this clinical trial is to compare two different nerve block techniques-the Pericapsular Nerve Group (PENG) block and the Lumbar Erector Spinae Plane Block (L-ESPB)-for managing pain after hip fracture surgery in…
- Conditions
- Femur Neck Fracture, Hip Fractures, Postoperative Pain
- Trial name
- NCT07910487
- Testing
- Pericapsular Nerve Group Block, Lumbar Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Beni-Suef University
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