Clinical trials: Arthroplasty
Length of Stay, Arthroplasty
Influence of the Operative Day on the Average Duration of Stay in Primary Hip and Knee Replacements
Reducing the length of stay (LOS) after primary arthroplasty is a relatively new target that arouses the attention of orthopedic surgeons in order to return home early through the fast recovery protocols but this goal is also…
- Trial name
- JourOpDMS (NCT03132831)
- Testing
- Determine the DMS of the Total Hip Prosthesis of the University Hospital of Amiens (PTH) and the Total Knee Prosthesis (PTG)
- Where
- France
- Volunteers
- 1,663 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Hip Osteoarthritis, Short Stem Prosthesis
Subsidence of Short Stem THA With DORR Type C
Total hip arthroplasty (THA) is a widely accepted procedure for the treatment of end-stage hip osteoarthritis. Neck preserving short stems have gained popularity in recent years, as they aim to preserve proximal femoral bone…
- Conditions
- Hip Osteoarthritis, Short Stem Prosthesis, Total Hip Arthroplasty (THA)
- Trial name
- NCT06768541
- Testing
- THA using a short stem
- Where
- Austria
- Volunteers
- 108 people
- Sponsor
- Krankenhaus Barmherzige Schwestern Linz
Joint Disease, Pain, Acute
Effect of Duloxetine on Opioid Use After Total Knee Arthroplasty
Post-discharge pain after total knee arthroplasty remains problematic; many patients have excessive pain at the 2 week time point (and often thereafter).
- Conditions
- Joint Disease, Pain, Acute, Pain, Chronic
- Trial name
- NCT03271151
- Testing
- Cymbalta
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Hospital for Special Surgery, New York
Complications; Arthroplasty, Complications; Arthroplasty, Mechanical
Using MRI To Detect Soft Tissue Reactions And Implant Integration As Related To Implant Modularity
Patients with a total hip replacement may require early revision surgery due to an adverse local tissue reaction or bone resorption that occurs due to wear debris released from the implant.
- Trial name
- NCT02255331
- Where
- United States
- Volunteers
- 587 people
- Sponsor
- Hospital for Special Surgery, New York
Osteoarthritis, Knee
Alignment Comparison Between TruMatch™ Personalized Solutions and Conventional Total Knee Replacement Instrumentation
This investigation is intended to provide clinical information about alignment using TruMatch™ and to compare the results to a conventional total knee replacement.
- Trial name
- NCT01108237
- Testing
- TruMatch™ Personalized Solutions, Total Knee Arthroplasty with Conventional Instrumentation.
- Where
- 4 sites in United States
- Volunteers
- 78 people
- Sponsor
- DePuy Orthopaedics
Medial Knee Compartment Arthritis
Oxford Partial Knee Kinematics Gait Analysis Study
The objective of this study is to compare the effect on gait of unicompartmental knee arthroplasty (UKA), using the Oxford Partial Knee, versus normal knee.
- Trial name
- NCT01454908
- Testing
- Oxford Partial Knee
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The CORE Institute
Total Blood Loss
Evaluation of Blood Loss and Pain in TKA With and Without Pneumatic Tourniquet, A Randomized Controlled Trial
The aim of our study is to determine whether the use of a tourniquet during TKA would affect total measured blood loss , operation time, postoperative complications; hemoglobin concentration; limb swelling and postoperative pain.
- Trial name
- NCT05144425
- Testing
- total knee arthroplasty with and without using pneumatic tourniquet
- Volunteers
- 100 people
- Sponsor
- Assiut University
Anaesthesia, Knee Surgery
Do Noise Cancelling Headphones Reduce Sedation Requirements in Primary Knee Arthoplasty
The study is a randomised trial of headphones with midazolam patient controlled sedation (intervention group) vs control group with no heaphones to compare sedation usage during knee replacement surgery under spinal.
- Trial name
- NOISE (NCT04752917)
- Testing
- Noise Cancelling headphones
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Arthropathy of Knee Joint
Improving Function After Knee Arthroplasty With Weight-Bearing Biofeedback
The purpose of this study is to determine if rehabilitation using weight-bearing biofeedback training following total knee arthroplasty (TKA) is more effective than standard rehabilitation methods in promoting weight-bearing…
- Trial name
- RELOAD (NCT01333189)
- Testing
- Weight-bearing biofeedback exercise, Standard of care exercise
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Colorado, Denver
Surgery, Knee Arthropathy
Evaluation of Arthroplasty Treatment
The aim of the study is to examine patients after knee and hip endoprosthesis in the longitudinal section and to evaluate the surgical outcome.
- Conditions
- Surgery, Knee Arthropathy, Hip Arthropathy, Prosthetic-joint Infection
- Trial name
- Endo-GEP (NCT07799818)
- Testing
- Joint replacement
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- University Hospital, Bonn
Physical Capability Outcomes
Physical Capability Outcomes After Single-Level PD-L vs Single-Level ALIF: a Multi-Center Clinical Trial
The purpose of this study is to compare the physical capability outcomes of patients who undergo single-level ProDisc-L disc replacement with those of patients who undergo stand-alone, single-level anterior lumbar interbody…
- Trial name
- NCT01055574
- Where
- 6 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gundersen Lutheran Medical Foundation
Total Hip Arthroplasty (THA), Accelerometers
Triaxial Accelerometry Study
This study looks at how physical activity levels are in the long term after hip surgery. Arthritis can make everyday movement difficult, and hip replacement surgeries-such as total hip arthroplasty (THA) and hip resurfacing-help…
- Conditions
- Total Hip Arthroplasty (THA), Accelerometers, Resurfacing Hip Arthroplasty
- Trial name
- NCT06883591
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 32 people
- Sponsor
- Rijnstate Hospital
Shoulder Osteoarthritis, Arthropathy Shoulder
Subscapularis Repair During Reverse Total Shoulder Arthroplasty
This multi-site study involving Northwestern Medicine, Beaumont Health, and Loyola Medicine seeks to answer the following question: do patients who undergo subscapularis (SSc) repair during reverse total shoulder arthroplasty…
- Trial name
- NCT05341518
- Testing
- Subscapularis repair
- Where
- 2 sites in United States
- Sponsor
- Northwestern University
Osteoarthritis
Multi-Center Study to Evaluate the ConforMIS iUni Knee Implant
Study is prospective and multi-center. Study will include 100 to 200 patients across up to 20 sites.The study sites will be located in the United States.The study objective is to evaluate the safety and performance of the…
- Trial name
- iUni (NCT01117571)
- Testing
- iUni® Unicompartmental Knee Resurfacing Device
- Where
- 8 sites in United States
- Volunteers
- 120 people
- Sponsor
- Restor3D
Hip Fractures
G7 Dual Mobility System Used in Total Hip Arthroplasty for the Treatment of Femoral Neck Fracture
This is a retrospective and prospective, multi-center, non-comparative, post market clinical follow-up study involving orthopedic surgeons skilled in THA and experienced implanting the devices included in this study.
- Trial name
- NCT04031209
- Testing
- G7 Acetabular System
- Where
- 7 sites in South Korea
- Volunteers
- 275 people
- Sponsor
- Zimmer Biomet
Hip Injuries and Disorders, Hip Fractures
Intramedullary Nail Versus Hip Arthroplasty in Unstable Trochanteric Hip Fractures
A hip fracture is a large burden to the patient with increased mortality, pain and increased need for daily assistance. Trochanteric fractures of the femur (FTF) represents about 35% of the hip fractures.
- Trial name
- TUFHIPRCT (NCT04868305)
- Testing
- Intramedullary nail, Hip arthroplasty
- Where
- Norway
- Volunteers
- 170 people
- Sponsor
- Helse Stavanger HF
Post-Operative Pain
Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Postoperative Pain Following Total Hip Arthroplasty.
The purpose of this phase 2 study is to evaluate the efficacy and safety of an analgesic drug candidate, VVZ-149 Injections. The study is designed as randomized, double-blind, parallel, and placebo-controlled study.
- Trial name
- NCT03347266
- Testing
- VVZ-149 injections
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Vivozon, Inc.
Knee Osteoarthritis
Outcome Study of Total Knee Arthroplasty in Asian Patients
To determine how the LCS mobile bearing knee system works within the Asian Population.
- Trial name
- DRAGON (NCT00733694)
- Testing
- LCS® Complete™ Mobile Bearing Knee Systems
- Where
- China
- Volunteers
- 607 people
- Sponsor
- DePuy International
Hip Osteoarthritis, Hip Arthritis
Alexis Retractor in Total Hip Arthroplasty
To determine if there is a difference in wound healing and surgical site infection (SSI) rates using the Alexis wound retractor vs. not using it in longitudinal direct anterior approach total hip arthroplasty.
- Trial name
- NCT07237737
- Testing
- Alexis wound retractor, Standard wound retractor
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- University of Miami
Pain, Postoperative
Pain Management After Shoulder Prosthesis: A Clinical Trial of Nerve Block and Local Infiltration
The purpose of this study is to determine the efficacy of local infiltration analgesia as compared to 48-hour interscalene block in treating pain after shoulder arthroplasty.
- Trial name
- NCT01362075
- Testing
- Local infiltration analgesia, Interscalene catheter
- Where
- 2 sites in Denmark
- Volunteers
- 74 people
- Sponsor
- Horsens Hospital
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