Clinical trials: Arthroplasty
Pain
Study to Evaluate The Analgesic Efficacy and Safety of Intravenous Paracetamol in Subjects With Postoperative Pain After Total Hip Arthroplasty
The main purpose is to evaluate the analgesic efficacy of 1g of intravenous (Iv) paracetamol versus i.v. placebo, administered every 6h, as measured by the reduction of the 24-hour cumulative dose of the opioid tramadol in the…
- Trial name
- NCT00344045
- Testing
- Paracetamol
- Where
- 5 sites in Spain
- Volunteers
- 86 people
- Sponsor
- Bristol-Myers Squibb
Liposomal Bupivacaine, Postoperative Recovery
A Analgesic Study of Adductor Canal &IPACK Block with Liposomal Bupivacaine in Knee Arthroplasty
To study the effectiveness of ACB and iPACK block with liposomal bupivacaine for postoperative analgesia in patients undergoing knee arthroplasty
- Conditions
- Liposomal Bupivacaine, Postoperative Recovery, Unilateral Knee Arthroplasty
- Trial name
- NCT06145165
- Testing
- Nerve block with ropivacaine and intravenous analgesia, Nerve block with liposomal bupivacaine and intravenous analgesia, Intravenous analgesia
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Arthroplasty Complications, Periprosthetic Fracture of Hip
LocalVancomycinPowderToPreventPeriprostheticJointInfection.
The purpose of this study is to evaluate the efficacy and complication profile of local vancomycin application in primary arthroplasty.
- Trial name
- NCT05697965
- Testing
- Vancomycin, Total knee or total hip arthroplasty
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pain, Postoperative
Postoperative Pain Treatment in Total Hip Arthroplasty: A Study to Assess the Effect of Local Analgesia
The purpose of this study is to determine whether the investigator standardized pain treatment plus local pain treatment is more effective than the investigator standardized pain treatment plus placebo in total hip arthroplasty.
- Trial name
- NCT00603083
- Testing
- Ropivacaine, Ketorolac and Adrenalin
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Vejle Hospital
Recovery Following Primary Total Knee Arthroplasty
Independent Exercise Compared With Formal Rehabilitation Following Primary Total Knee Replacement
In this study we plan to compare the efficacy of independent exercises performed by the patients at home to formal rehabilitation therapy following primary total knee replacement.
- Trial name
- NCT01826305
- Testing
- Formal Rehabilitation Therapy, Independent Exercise Cohort
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of California, San Francisco
Knee Osteoarthritis, Total Knee Arthroplasty
Effect of Hemovac Drain Removal on Early Outcomes After Total Knee Arthroplasty
This study aims to evaluate whether the timing of Hemovac drain removal affects early clinical outcomes after primary total knee arthroplasty (TKA).
- Trial name
- NCT07342894
- Where
- Turkey (Türkiye)
- Volunteers
- 207 people
- Sponsor
- Ankara City Hospital Bilkent
Femoral Neck Fracture, Infection
Early Periprosthetic Joint Infection and Outcome Debridement, Antibiotics and Implant Retention
Introduction Periprosthetic joint infection (PJI) is a severe complication to hip arthroplasty for femoral neck fractures (FNF).
- Trial name
- DAIR (NCT02771639)
- Testing
- Hip arthroplasty
- Volunteers
- 736 people
- Sponsor
- Sundsvall Hospital
Arthroplasty, Replacement, Hip
Intraarticular Analgesia After Total Hip Arthroplasty, a Randomised Study
The purpose of this study is to determine whether wound infiltration with following single-shot bolus injection with local anesthetic and NASIDs are effective in the treatment of postoperative pain after total hip replacement…
- Trial name
- NCT00289419
- Testing
- Epidural Ropivacaine, morphine, Ropivacaine, Ketorolac and Adrenaline
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Knee Osteoarthritis
Staged Versus Simultaneous Bilateral Knee Arthroplasty
The purpose of this study is to assist surgeons and patients in answering the question "Should I have both knees replaced at the same time, or should I just do one and wait to do the second one?"
- Trial name
- NCT03564730
- Testing
- Simultaneous Knee Arthroplasty (UKA), Staged Knee Arthroplasty (UKA)
- Where
- 8 sites in Canada
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Innovation Centre
Arthroplasty, Replacement, Knee, Thromboembolism
RE-MODEL Dabigatran Etexilate 150mg or 220mg Once Daily (o.d.) Versus (v.s.) Enoxaparin 40mg o.d. for Prevention of Thrombosis After Knee Surgery
A phase III, randomised, parallel-group, double-blind, active controlled study to investigate the ef ficacy and safety of two different dose regimens of orally administered dabigatran etexilate capsule s [150 or 220 mg once daily…
- Trial name
- NCT00168805
- Testing
- enoxaparin, dabigatran etexilate
- Where
- 105 sites in Australia, Austria and 13 more
- Volunteers
- 2,101 people
- Sponsor
- Boehringer Ingelheim
Degenerative Joint Disease
Journey II BCS EU Observational Trial
Post-market study to confirm the safety and efficacy of the Journey II BCS knee prosthesis.
- Trial name
- NCT02211794
- Testing
- data collection
- Where
- 5 sites in Belgium, Italy and 3 more
- Volunteers
- 179 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Total Knee Arthroplasty
Return to Activity After Total Knee Arthroplasty
This multicenter research project aims to correlate objective testing of muscle mass, muscle strength, neuromuscular activation, walking speed and other functional tests with everyday activity and subjective quality of life after…
- Trial name
- NCT07006545
- Testing
- Return to Activity Battery
- Where
- 2 sites in Germany
- Volunteers
- 400 people
- Sponsor
- University Hospital, Bonn
Postoperative Hemorrhage
Efficacy of Intra-auricular Tranexamic Acid in Total Knee Arthroplasty
Tranexamic acid an antifibrinolytic that develops its anti-haemorrhagic action by inhibiting fibrinolytic activities of plasmin and many studies confirms its effectiveness in decreasing blood loss.
- Trial name
- NCT04085575
- Testing
- Acide Tranexamique
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Montauban
Knee Osteoarthritis
Early Outcomes of MAKO Medial Unicompartmental Knee Arthroplasty
To determine if robotically-assisted UKA results in more consistent and improved component positioning and better patient reported outcome scores compared to manual TKA and MAKO TKA.
- Trial name
- NCT05736601
- Testing
- focus motion knee brace
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Washington University School of Medicine
Osteoarthritis
Comparing Surgery Versus Standard Physical Therapy in Treating People With a Meniscal Tear and Osteoarthritis
There are two cartilage structures, called menisci, in each knee joint. A torn meniscus can be caused by a traumatic injury or aging-related degeneration.
- Trial name
- NCT00597012
- Testing
- Arthroscopic partial menisectomy, Standard physical therapy, Postoperative rehabilitative physical therapy
- Where
- 7 sites in United States
- Volunteers
- 351 people
- Sponsor
- Brigham and Women's Hospital
Arthroplasty, Replacement, Knee, Analgesia
Analgesic Effect of Peripheral Cutaneous Nerve Block of Knee Joint After Total Knee Arthroplasty
Local anesthesia was performed on patients with total knee arthroplasty (TKA) through two different injection sites of local anesthetics and two local anesthetic drug .
- Trial name
- NCT05202730
- Testing
- New local anesthesia injection site and new local anesthetic drug formulation.
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Diwuweilong
Venous Thrombosis, Arthroplasty, Replacement, Hip
Lower Limb Blood Flow Geko vs Foot Pump
The aim of this pilot study was to assess venous flow parameters in patients following total hip arthroplasty, comparing an intermittent pneumatic compression foot device with a portable neuromuscular electrostimulator device.
- Trial name
- NCT03317145
- Testing
- Neuromuscular electrostimulation (NMES) device, Intermittent pneumatic compression (IPC) device
- Volunteers
- 10 people
- Sponsor
- Hampshire Hospitals NHS Foundation Trust
Arthroplasty, Replacement, Physical Therapy
Effectiveness of a Novel Gaming System on Post-operative Rehabilitation Outcomes After Total Knee Arthroplasty
This study aims to evaluate the effectiveness of a novel, game-based rehabilitation system, consisting a sensor-equipped knee sleeve and a mobile application, on rehabilitation outcomes after Total Knee Arthroplasty (TKA)…
- Trial name
- NCT04080401
- Testing
- Game-based rehabilitation exercise, Conventional brochures of rehabilitation exercise
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- Tan Tock Seng Hospital
Arthritis Knee, Bariatric Surgery Candidate
Risk of Revision Following Knee Arthroplasty in Bariatric Surgery Patients
Previous studies have investigated the outcomes of Knee Arthroplasty (KA) following Bariatric Surgery (BAS), but with substantial limitations as not stratifying for Body Mass Index (BMI) at time of KA or not addressing the type…
- Conditions
- Arthritis Knee, Bariatric Surgery Candidate, Prosthesis Failure, Prosthesis Survival
- Trial name
- NCT06433700
- Testing
- BAS, Non-BAS
- Where
- Denmark
- Volunteers
- 99,965 people
- Sponsor
- Bispebjerg Hospital
Postoperative Pain Management After Total Hip Arthroplasty
Treatment of Postoperative Pain After Total Hip Arthroplasty Using Intravenous Lidocaine Infusion
This study will focus on patients undergoing total hip arthroplasty and Loma Linda University Medical Center \& East Campus. These patients will be randomized to receive a low dose lidocaine infusion or placebo, in addition to…
- Trial name
- NCT01108562
- Testing
- Lidocaine, Normal Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
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