Clinical trials: Arthroplasty
Osteoarthritis (OA) of the Hip
Gait After THA: Direct Anterior vs Manual Posterior vs Robotic Posterior
The purpose of this study is to evaluate the gait biomechanics following THA on 3 groups of subjects undergoing DAA (manual) and PA (manual and robotic) surgical approaches.
- Trial name
- NCT07226973
- Testing
- Total hip arthroplasty via direct anterior approach (manual, non-robotic), Total hip arthroplasty via posterior approach (manual, non-robotic), Robotic-assisted total hip arthroplasty via posterior approach
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Ochsner Health System
Non-rheumatoid Wrist Arthritis
Motec Versus Remotion Total Wrist Arthroplasty - A Prospective Study
The purpose of this study is to determine the difference in the results between Motec and Remotion wrist arthroplasty in the treatment of non-rheumatoid wrist arthritis.
- Trial name
- NCT01842724
- Testing
- Motec total wrist arthroplasty, Remotion total wrist arthroplasty
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Arthritis, Arthritis (Knee)
Kinematic Alignment in Total Knee Arthroplasty - a Double-blind Randomised Controlled Trial Between Robotic and Caliper-based Techniques
Knee replacement surgery is a surgery designed to treat severe arthritis of the knee. However, as many as 20% of patients are not satisfied with the results of their surgery.
- Conditions
- Arthritis, Arthritis (Knee), Osteoarthritis, Osteoarthritis Knee Pain
- Trial name
- NCT06709703
- Testing
- Kinematic aligned total knee replacement
- Volunteers
- 200 people
- Sponsor
- Université de Sherbrooke
CMC-1 Osteoarthritis, Trapeziometacarpal Osteoarthritis
Pyrocardan® Implant Arthroplasty or LRTI for Trapeziometacarpal Osteoarthritis
This is a randomized controlled trial comparing the Pyrocardan® implant (intervention group) with the standard ligament reconstruction and tendon interposition (LRTI) (control group).
- Trial name
- NCT06290986
- Testing
- Pyrocardan® implant, Ligament reconstruction and tendon interposition (LRTI)
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Herlev and Gentofte Hospital
Knee Arthroplasty
Clinical Outcomes of Knee Replacement
The objective of this study is to document the demographic and clinical characteristics and the long-term clinical outcomes of patients who require a robot assisted knee arthroplasty.
- Trial name
- NCT01705366
- Testing
- Non-MAKO® Robot Assisted Total Knee Arthroplasty, MAKO® Robot Assisted Medial Knee Arthroplasty, MAKO® Robot Assisted Medial and PF Knee Arthroplasty
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- Northwest Surgical Specialists, Vancouver
Total Knee Replacement, Knee Osteoarthritis
Circulatory Exercise After Total Knee Replacement
Total knee replacement is commonly associated with early postoperative inflammation, edema, pain, and reduced mobility. This randomized controlled trial will evaluate whether adding a simple circulatory exercise program to…
- Conditions
- Total Knee Replacement, Knee Osteoarthritis, Postoperative Edema, Postoperative Inflammation
- Trial name
- NCT07688642
- Testing
- standard postoperative TKR rehabilitation, Standard Rehabilitation Plus Circulatory Exercise
- Volunteers
- 68 people
- Sponsor
- Assiut University
Knee Arthroplasty
Unipolar vs. Bipolar Hemostasis in Total Knee Arthroplasty: A Prospective Randomized Trial
The use of Aquamantys during total knee arthroplasty will reduce drain output and the necessity for blood transfusions.
- Trial name
- NCT01003080
- Testing
- Aquamantys Device, Standard of care treatment for hemostasis during a total knee arthroplasty.
- Where
- 2 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Total Knee Replacement, Genicular Nerve Block
Genicular and Anterior Femoral Cutaneous Nerve Blocks for Total Knee Arthroplasty
The goal of this randomized controlled trial is to examine if there is a relationship between the addition of the genicular nerve block and anterior femoral cutaneous nerve block in providing analgesia and the use of oral and…
- Conditions
- Total Knee Replacement, Genicular Nerve Block, Opioid Use
- Trial name
- NCT05980546
- Testing
- Bupivacaine Injection, Dexamethasone injection, Fentanyl
- Where
- United States
- Volunteers
- 244 people
- Sponsor
- Hospital for Special Surgery, New York
Pain
Caldolor Versus Caldolor Plus OFIRMEV in Total Knee or Hip Arthroplasty Surgeries
The objective of this study is to compare the effectiveness and of perioperative use of Caldolor alone and in combination with OFIRMEV in total knee or hip arthroplasty procedures.
- Trial name
- NCT01773005
- Testing
- Ofirmev, Caldolor
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Anita Gupta
Postoperative Analgesia
Comparison Between the Effect of Infiltration Between the Popliteal Artery and Capsule of the Knee Block Versus Selective Tibial Nerve Block for Postoperative Analgesia in Patient Undergoing Total Knee Arthroplasty. A Prospective Randomized Study
Comparison Between the Effect of Infiltration Between the Popliteal Artery and Capsule of the Knee Block Versus Selective Tibial Nerve Block for Postoperative Analgesia in Patient Undergoing Total Knee Arthroplasty.
- Trial name
- NCT05473559
- Testing
- Adductor canal block with Ipack block or selective tibial nerve block
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tanta University
Osteoarthritis, Shoulder
TSA Techniques in Glenohumeral OA
Osteoarthritis (OA) of the shoulder is a disease resulting from the wearing down of cartilage over time. OA can produce pain and dysfunction at the affected joint and is a growing occurrence in an aging population.
- Trial name
- NCT02966886
- Testing
- Eccentric Reaming, Augmented Glenoid Component Implantation, Posterior Glenoid Bone Grafting
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- Ottawa Hospital Research Institute
Anemia, Knee Arthropathy
Effect of IV Iron Isomaltoside on Postoperative Anemia in Total Knee Arthroplasty Patients
Postoperative anemia is a frequent complication after total knee arthroplasty, with an incidence of 87%. Iron supplementation is known to be effective in treatment and prevention of postoperative anemia.
- Trial name
- NCT03470649
- Testing
- Iron Isomaltoside 1000
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Pain, Joint, Knee Arthropathy
Comparison Of The Analgesic Efficacy Of IPACK (Interspace Between The Popliteal Artery And Capsule Of The Posterior Knee) Block Alone And IPACK Block Combined With Genicular Block In Patients Planned For Total Knee Arthroplasty
The IPACK (interspace between the popliteal artery and capsule of the posterior knee) block is a regional anesthesia technique in which a local anesthetic is infiltrated under ultrasound guidance between the popliteal artery and…
- Conditions
- Pain, Joint, Knee Arthropathy, Anesthesia, Orthopedic Disorder
- Trial name
- NCT06065878
- Testing
- IPACK + Genicular Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cenk Gacemer
Osteoarthritis, Avascular Necrosis
Trilogy AB Acetabular Hip System Post Approval Study
This is a post-approval study with prospective enrollment in the United States and a retrospective enrollment outside the United States to obtain functional, quality of life and radiographic data, which will facilitate assessment…
- Conditions
- Osteoarthritis, Avascular Necrosis, Congenital Hip Dysplasia, Traumatic Arthritis
- Trial name
- NCT00715026
- Testing
- Trilogy AB Acetabular Hip Implant System
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Zimmer Biomet
Anesthesia, Catheter Blockage
The Efficacy of Continuous Femoral Nerve Catheter Orifice Configuration for Postoperative Analgesia in Knee Arthroplasty
Femoral nerve catheter for postoperative analgesia will be included in the adult patients undergoing total knee arthroplasty included in the study.
- Conditions
- Anesthesia, Catheter Blockage, Knee Arthropathy, Pain, Postoperative
- Trial name
- NCT04202250
- Testing
- CEMP (closed-ended multiport catheter) group, OESP (open-ended single port catheter) group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gulhane School of Medicine
CMC Arthritis, Occupational Therapy
Trapeziectomy and Suture Suspensionplasty for Thumb Carpometacarpal Arthritis - Is In-Clinic Therapy Needed?
The study is a randomized, controlled trial to evaluate the efficacy of formal occupational therapy on outcomes following CMC arthroplasty
- Conditions
- CMC Arthritis, Occupational Therapy, Hand Arthritis
- Trial name
- NCT06820528
- Testing
- Occupational Therapy, Home Exercise Program
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Julie Nuelle
Evaluate Postsurgical Hematoma
Efficacy of PICO Compared to Opsite Post-Op Visible on Surgical Wound in Patients at High Risk of Local Complications, Undergoing Hip Arthroplasty
Evaluate the effect of the PICO medical device, compared to the Opsite Post-Op Visible medical device, in reducing the formation of postsurgical hematoma in the surgical wound of patients at high risk of local complications…
- Trial name
- PICO-PTA (NCT05189392)
- Testing
- PICO
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Knee Arthropathy
A Pilot Feasibility Study Comparing Smartphone Home-based Rehabilitation Program Against the Usual Hospital and Outpatient Physiotherapy Care on Clinical and Cost Effectiveness for Total Knee Replacement Patients
Knee osteoarthritis (OA) is a common, chronic, and costly condition whilst total knee replacement (TKR) is a common orthopaedic surgical intervention.
- Trial name
- NCT06248034
- Testing
- Smartphone application with tele-monitoring rehabilitation, Hospital-based rehabilitation program
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Arthroplasty, Replacement, Knee
A Study to Evaluate the Safety and Efficacy of YM150 in Patients With Knee Replacement Surgery
To evaluate the safety and efficacy of twice daily dosing and once daily dosing of YM150 in subjects undergoing primary elective knee replacement surgery
- Trial name
- PEARL (NCT00595426)
- Testing
- YM150, Warfarin
- Where
- 54 sites in United States, Canada
- Volunteers
- 685 people
- Sponsor
- Astellas Pharma Inc
Pain, Back, Pain, Neck
Preliminary Muscle Contraction in the Rehabilitation and Prevention of Degenerative Pain in the Locomotor System
RESEARCH OBJECTIVE: To investigate the effect of muscle preliminary contraction in the rehabilitation and prevention of degenerative pain in the spine, hip, knee, ankle, shoulder, elbow, and ankle joints, as well as after hip and…
- Conditions
- Pain, Back, Pain, Neck, Pain, Hip Burning, Pain, Shoulder
- Trial name
- PMQRPDP (NCT06415825)
- Testing
- Standard advice and Preliminary muscle contraction, Standard advice
- Volunteers
- 216 people
- Sponsor
- Medical University of Sofia
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.