Clinical trials: Arthroplasty
Total Knee Arthroplasty, Pain Management
Analgesic Efficacy of Preemptive Stepwise Infiltration Anesthesia for Perioperative Analgesia After TKA
This is a single-center prospective cohort study in which patients were evaluated by inclusion and exclusion criteria before total knee arthroplasty (TKA).
- Trial name
- NCT06600815
- Testing
- preemptive stepwise infiltration anaesthesia(PSIA), postoperative local infiltration analgesia(PLIA)
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Osteoarthritis, Rheumatoid Arthritis
Clinical Study Comparing Two Implant Surface Finishes in Patients Undergoing Cementless Total Hip Replacement
Prospective, randomized study of Summit Porocoat versus Summit DuoFix HA in total hip arthroplasty
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Avascular Necrosis
- Trial name
- SPD (NCT00306917)
- Testing
- non-coated femoral hip stem, coated femoral hip stem
- Where
- United States
- Volunteers
- 245 people
- Sponsor
- DePuy Orthopaedics
Persistent Postsurgical Pain, Arthritis Knee
Persistent Pain After Knee Replacement
This study is a nationwide cross-sectional survey on pain and satisfaction after knee arthroplasty (KA). Please find the full protocol uploaded at ClinicalTrials.gov The goal of this observational study is to study pain and…
- Conditions
- Persistent Postsurgical Pain, Arthritis Knee, Neuropathic Pain, Opioid Use
- Trial name
- NCT05900791
- Testing
- Primary knee arthroplasty
- Where
- Denmark
- Volunteers
- 3,710 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Knee Pain Chronic, Rheumatoid Arthritis
Cemented vs Cementless Persona Keel RCT
The main objective of this study is to evaluate the safety, performance, and clinical benefits of the Persona Keel cementless and cemented knee.
- Conditions
- Knee Pain Chronic, Rheumatoid Arthritis, Osteoarthritis, Traumatic Arthritis
- Trial name
- NCT05630053
- Testing
- Cementless Persona Knee System, Cemented Persona Knee System
- Where
- 7 sites in United States
- Volunteers
- 300 people
- Sponsor
- Zimmer Biomet
Opioid Use
Opioid Consumption and Disposal After Shoulder Arthroplasty
Opioid medications are widely used after many orthopedic procedures and are routinely prescribed after shoulder replacement surgery.
- Trial name
- NCT05525975
- Testing
- Educational materials
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Brendan M. Patterson
Total Knee Arthroplasty (TKA)
Total Intravenous Anesthesia vs Spinal Anesthesia in Patients Undergoing Unilateral Primary Total Knee Arthroplasty
The purpose of this study is to compare same-day discharge rates and recovery outcomes across an adult patient population undergoing elective Total Knee Arthroplasty (TKA), and randomized to receive either spinal block anesthesia…
- Trial name
- NCT07672301
- Testing
- Total IntraVenous Anesthesia (TIVA), Spinal-Block, Electroencephalogram (EEG)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Chicago
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Functional Outcomes and Quality of Life in Hip, Knee and Shoulder Arthroplasty
PaRIS-IOR is a prospective observational study that aims to collect and analyze functional outcomes and quality of life reported by patients undergoing elective hip, knee and shoulder arthroplasty at the IRCCS Rizzoli Orthopedic…
- Conditions
- Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Shoulder
- Trial name
- PaRIS-IOR (NCT03790267)
- Testing
- Questionnaire administration
- Where
- Italy
- Volunteers
- 4,260 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis, Unicompartmental Knee Arthroscopy
A Single-Center, Epidemiological Study of the Survivorship of the DePuy Sigma HP Unicompartmental Knee Prosthesis
This study will be conducted to assess the survivorship of a particular prosthesis used in unicompartmental knee arthroplasties.
- Trial name
- NCT01656694
- Testing
- DePuy Sigma HP Partial Knee
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Mississippi Sports Medicine and Orthopaedic Center
Hip Osteoarthritis, Noninflammatory Degenerative Joint Disease
Randomized Controlled RSA Study Comparing the Taperloc Complete Versus the Taperloc Complete Microplasty.
This is a single center, prospective, randomized controlled study. The primary objective of this study is to measure migration over two years with RSA.
- Conditions
- Hip Osteoarthritis, Noninflammatory Degenerative Joint Disease, Avascular Necrosis, Correction of Functional Deformity
- Trial name
- NCT03409666
- Testing
- Taperloc Complete Microplasty stem, Taperloc Complete Reduced Distal stem
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Zimmer Biomet
Arthroplasty, Knee Replacement, Pain, Postoperative
The Effect of Dexamethasone on Pain After Total Knee Replacement Surgery
The purpose of this study is to examine, if a single-dose of dexamethasone given during the operation, alleviates pain after knee replacement surgery.
- Trial name
- NCT03034733
- Testing
- Dexamethasone, Sodium Chloride, (24)NaCl 0,9%
- Where
- Finland
- Volunteers
- 27 people
- Sponsor
- University of Oulu
Knee Arthropathy
Influence of Different Prostheses on Postoperative Clinical Function in Total Knee Arthroplasty
Exploring differences in knee function after surgery with different types of prostheses(Cruciate ligament retaining(CR) VS. posterior stabilizing(PS))
- Trial name
- NCT06617819
- Testing
- CR prosthesis, PS prosthesis
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Total Knee Arthroplasty
Insertion Distance of Femoral Perineural Catheters in the Context of Major Knee Surgery.
This study is designed to compare femoral perineural catheter insertion distances, in order to help determine which is the best for pain relief after knee surgery.
- Trial name
- NCT00726219
- Testing
- Femoral perineural catheter
- Where
- 2 sites in Canada
- Volunteers
- 72 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Arthritis Knee, Bariatric Surgery Candidate
Risk of Revision Following Knee Arthroplasty in Bariatric Surgery Patients
Previous studies have investigated the outcomes of Knee Arthroplasty (KA) following Bariatric Surgery (BAS), but with substantial limitations as not stratifying for Body Mass Index (BMI) at time of KA or not addressing the type…
- Conditions
- Arthritis Knee, Bariatric Surgery Candidate, Prosthesis Failure, Prosthesis Survival
- Trial name
- NCT06433700
- Testing
- BAS, Non-BAS
- Where
- Denmark
- Volunteers
- 99,965 people
- Sponsor
- Bispebjerg Hospital
Osteoarthritis
Standard Total Knee Arthroplasty Using Platelet Rich Plasma (PRP)
Clinical study to determine if there is a difference in hemoglobin level between patients undergoing total knee arthroplasty with and without platelet-rich plasma.
- Trial name
- NCT01075230
- Testing
- Total knee arthroplasty
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Exactech
Osteoarthritis of the Knee or Hip
Comparison Between Blocks or Not in Joint Arthroplasty
The purpose of this study is to evaluate the effect on postoperative pain, opioid consumption and function by adding a combination of regional blocks with local anaesthetic before total hip- and knee arthroplasty compared to…
- Trial name
- BLAST (NCT06230081)
- Testing
- Ropivacain 5 mg/ml + Clonidine
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Region Skane
Osteoarthritis
Early Mobilization After Total Knee Arthroplasty
Patients undergoing elective total knee arthroplasty are randomized to either intrathecal anesthesia, wound infiltration with local anesthetics and standardized postoperative care (NA = neuraxial anesthesia) or general…
- Trial name
- NCT01604382
- Testing
- General Anesthesia, Neuraxial anesthesia
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Skane
Arthritis Knee, Magnesium Sulfate
Magnesium and Postoperative Pain
With ongoing advancements in healthcare leading to prolonged life expectancy, orthopedic surgeries are increasingly performed in elderly patients.
- Conditions
- Arthritis Knee, Magnesium Sulfate, Dexmedetomidine
- Trial name
- NCT03253224
- Testing
- Magnesium Sulfate, Normal saline
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Seoul National University Hospital
THA, Obesity
The Impact of Obesity on Short Stem Total Hip Arthroplasty
The purpose of this study is to review the impact of obesity on subsidence and clinical outcome after short stem total hip arthroplasty.
- Trial name
- NCT06430723
- Testing
- Total hip arthroplasty
- Where
- Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Krankenhaus Barmherzige Schwestern Linz
Total Knee Arthroplasty, Rehabilitation
Effect of Fast Inpatient Rehabilitation After TKA
Rehabilitation is an important part of the post-operative treatment after TKA by consensus. This study intends to analysis whether fast inpatient rehabilitation after TKA can improve knee joint or general function, and ultimately…
- Trial name
- NCT04458480
- Testing
- Fast Inpatient Rehabilitation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Knee Osteoarthritis
Investigating the Role of Motivational Interviewing in Swedish Patients Undergoing Knee Arthroplasty
Knee arthroplasty is a successful surgical treatment for end-stage osteoarthritis. Most patients are satisfied with the result, however, 10% of the patients have remained dissatisfied over the last decades despite the advantages…
- Trial name
- NCT05940246
- Testing
- Motivational Interviewing
- Where
- Sweden
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
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