Clinical trials: Arthroplasty
Persistent Postsurgical Pain, Arthritis Knee
Weight Change and the Risk of Chronic Pain Following Hip and Knee Arthroplasties
The study is a nationwide, register-based cohort survey study. The objective of this study is to investigate whether weight change is associated with the incidence of persistent postoperative pain following total hip arthroplasty…
- Conditions
- Persistent Postsurgical Pain, Arthritis Knee, Arthropathy of Knee, Arthropathy of Hip
- Trial name
- NCT06024161
- Testing
- Weight gain, Weight loss, Weight unchanged
- Volunteers
- 6,400 people
- Sponsor
- Bispebjerg Hospital
Osteoarthritis, Post-traumatic Arthritis
A Randomised Single Centre Study to Compare the Long-term Performance of Acryloc™ and Palacos® R Bone Cements in Primary Total Hip Replacement
The purpose of this study is to monitor the stability of a total hip replacement within the thigh bone when used in artificial hip joints implanted with two different bone cements, Acryloc™ and Palacos® R, in the treatment of…
- Conditions
- Osteoarthritis, Post-traumatic Arthritis, Avascular Necrosis
- Trial name
- NCT00208403
- Testing
- Acryloc™ GHV, Palacos R
- Where
- Norway
- Volunteers
- 36 people
- Sponsor
- DePuy International
Wound Complication
Closed Incision Negative Pressure Therapy vs Standard of Care
High risk patients who receive direct anterior approach total hip arthroplasty are more likely to experience wound complications.
- Trial name
- Prevena (NCT03061903)
- Testing
- Prevena, Aquacel
- Where
- 3 sites in United States, Canada
- Volunteers
- 122 people
- Sponsor
- Columbia University
Femoral Neck Fracture, Trochanteric Pain
Hip Abductor Strengths, Limping and Trochanteric Tenderness After Hip Arthroplasty Due to Femoral Neck Fracture
A prospective cohort study to compare the direct lateral and poster-lateral approach concerning abductor function. Patients admitted with a femoral neck fracture operated with a hemiarthroplasty through a direct lateral or a…
- Trial name
- HASAP (NCT02247661)
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Sundsvall Hospital
Total Knee Arthroplasty
The Use of Continuous Wound Infusion Analgesia in Total Knee Arthroplasty
The main purpose of this study is to determine if there is improvement in pain and other patient outcomes when using a continuous wound analgesia system after total knee replacement, compared to usual methods of pain control.
- Trial name
- NCT00724074
- Testing
- On-Q PainBuster with Bupivacaine, Usual Care
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Capital Health, Canada
Hip-surgery, Knee-surgery
Prospective, Randomized Study of 2 Different Wound Dressings
The primary objective of this investigation is to evaluate the performance of a self-adhesive absorbent post-operative dressing coated with a soft silicone layer in minimize the risk of the development of blistering in subjects…
- Conditions
- Hip-surgery, Knee-surgery, Spinal-surgery
- Trial name
- Close (NCT01988818)
- Testing
- Mepilex® Border Post-Op, standard wound dressing
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Cologne
Postoperative Delirium
Protocol for Observational Study of Post op Delirium Following Total Joint Arthroplasties
The incidence of post-operative delirium in the South-east Asian population is not known. Through a prospective, single centre, observational study, the investigators aim to characterize the incidence and risk factors of delirium…
- Trial name
- NCT03260218
- Where
- Singapore
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Localized, Primary Osteoarthritis, Post-traumatic Arthrosis of Other Joints, Shoulder Region
Clinical Outcomes in Shoulder Hemi-arthroplasty Using a PyC Spherical Interpositional Implant
The INSPYRE implant is a new range of shoulder hemi-arthroplasty device. It consists of a Pyrocarbon spherical interpositional implant and is indicated in primary surgery to relieve severe pain or significant disability caused by…
- Conditions
- Localized, Primary Osteoarthritis, Post-traumatic Arthrosis of Other Joints, Shoulder Region, Avascular Necrosis of the Head of Humerus
- Trial name
- NCT02424760
- Testing
- Shoulder hemi-arthroplasty
- Volunteers
- 67 people
- Sponsor
- Stryker Trauma and Extremities
Pain, Postoperative Complications
Acupuncture for Pain Management After Hip or Knee Arthroplasty
The purpose of this study is to determine whether patients treated with acupuncture post-operatively following knee or hip arthroplasty achieve better pain control as measured by the Visual Analog Scale and pain medication use.
- Trial name
- NCT00455182
- Testing
- Acupuncture, Standard medical care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- HealthEast Care System
Anesthesia, Conduction, Pain, Postoperative
Combined PENG and LFCN Block for Total Hip Arthroplasty
A clinical trial investigating the effect of a combined locoregional anesthesia technique on the postoperative analgesia outcomes after a total hip arthroplasty. A PENG block will be used in combination with a LFCN block.
- Conditions
- Anesthesia, Conduction, Pain, Postoperative, Arthroplasty, Replacement, Hip
- Trial name
- NCT04996290
- Testing
- PENG + LFCN block, Ropivacaine injection
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Antwerp
Knee Injuries
Optimized Loading Response by JOURNEY II BCS Knee Increases Daily Physical Activity and Functions
Smith \& Nephew's first edition of the Journey posterior stabilizing total knee arthroplasty was analyzed by the Center for Musculoskeletal Research in a past research study, and it was determined that subjects experienced more…
- Trial name
- NCT02335710
- Testing
- Journey II BCS TKA
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Thumb Carpometacarpal Joint Osteoarthritis
Biomechanical Evaluation With Finite Element Models in Thumb Carpometacarpal Osteoarthitis: Prospective Comparative Analysis of Loads in Arthroplasty With or Without Implants
To better understand the load distribution in the Thumb Carpometacarpal Joint (CMC joint) in presence of osteoarthritis and how surgery by means of a suspension-resection arthroplasty or a joint replacement by means of a metal…
- Trial name
- NCT07614269
- Testing
- Trapezectomy and carpometacarpal joint resection-supension arthroplasty, Trapeziometacarpal joint prosthesis
- Volunteers
- 40 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Arthritis, Knee Osteoarthritis
Stated-Preferences in Knee Arthroplasty
The primary objectives of this study are to apply best-practice stated-preference methods to quantify patient preferences for benefit-risk tradeoffs associated with arthroplasty treatment options for end-stage osteoarthritis of…
- Conditions
- Arthritis, Knee Osteoarthritis, Arthropathy of Knee
- Trial name
- NCT03058380
- Testing
- Stated-Preferences Evaluation Instrument
- Where
- United States
- Volunteers
- 348 people
- Sponsor
- Duke University
Osteoarthritis
The Effect of Implant Coating (BoneMaster) on Migration and Clinical Outcome in Hip Arthroplasty With the Exceed Cup
This study focuses on the effect of the hydroxyapatite coating with BoneMaster on the fixation of the hip prosthesis in primary hip alloplasty.
- Trial name
- NCT02311179
- Testing
- Prosthesis, BoneMaster-Exceed cup (Biomet), Prosthesis Exceed cup without HA (Biomet)
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- University of Aarhus
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Russian Non-Interventional Study on Compliance of Venous Thromboembolism (VTE)
This is a local, prospective, multicenter, non-interventional, observational study. Primary objective is to describe how in "real life" thromboprophylaxis is carried out after the discharge from a hospital in the patients who…
- Trial name
- SOPRANO (NCT01444586)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- Russia
- Volunteers
- 2,293 people
- Sponsor
- Bayer
Arthroplasty Complications, Physical Disability
Investigation of the Effects of Balance Training on Balance and Functional Status Patients With Total Hip Arthroplasty
The purpose of this study is to investigate the effects of balance training in patients with THA until 26 weeks postoperatively. Thirty-two patients with hip osteoarthritis who were candidates for THA were recruited to the study.
- Conditions
- Arthroplasty Complications, Physical Disability, Osteoarthritis, Hip
- Trial name
- NCT04433962
- Testing
- Exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Ege University
Osteoarthritis of the Knee
Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty
Total knee arthroplasty (TKA) is associated with moderate to severe postoperative pain, causing patient discomfort, mobilisation and hospital discharge. The aim of this study is to: 1.
- Trial name
- NCT00562627
- Testing
- ropivacaine, adrenaline, ketorolac
- Where
- Norway
- Volunteers
- 102 people
- Sponsor
- Asker & Baerum Hospital
Postoperative Pain
Local Anesthetics After Total Knee Arthroplasty
The aim of this randomized, double-blind and placebo-controlled study is to evaluate the specific role of injection of local anesthetic into the intra- vs. extraarticular tissues after toal knee arthroplasty.
- Trial name
- NCT00518674
- Testing
- local infiltration analgesia
- Volunteers
- 32 people
- Sponsor
- Hvidovre University Hospital
Bone Scintigraphy and Knee Arthroplasty
Bone Scintigraphy and Unicompartimental Knee Arthroplasty
Study the potential interest of bone scintigraphy for patients undergoing unicompartmental knee arthroplasty
- Trial name
- PUC-INTEVO (NCT03145090)
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Brest
Thumb Carpometacarpal Arthritis
Suture Fixation System Versus Tendonous Reconstruction in Carpometacarpal (CMC) Arthroplasty
Thumb carpometacarpal (CMC) arthritis affect 1 in 4 females and 1 in 12 males. Patients who fail to respond to conservative treatment may benefit from surgery; however, controversy exists over the most effective surgical…
- Trial name
- NCT01121874
- Testing
- Ligament reconstruction with suture fixation system, Ligament Reconstruction with Tendon Interposition (LRTI)
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- J&M Shuler
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