Clinical trials: Arthroplasty
Knee Arthroplasty
VEGA System® Study in the Total Knee Arthroplasty
This post-market clinical follow-up study intends to investigate long-term functionality of the VEGA System®. The design of the VEGA System® is meant to provide the patient with more knee mobility compared to their pre-operative…
- Trial name
- NCT02944409
- Testing
- total knee prothesis VEGA System
- Where
- 2 sites in France
- Volunteers
- 125 people
- Sponsor
- BBraun Medical SAS
Arthroplasty, Replacement, Knee, Synovectomy
Synovectomy in Primary Total Knee Arthrplasty
The aim of total knee arthroplasty is to achieve best patient functional outcomes, improve patient pain score and satisfaction. Synovial proliferation is a common finding in arthritic knees.
- Trial name
- NCT03778463
- Testing
- Synovectomy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Knee Arthroplasty, Total
The Analgesic Efficacy of Protocol for Primary Total Knee Arthroplasty (TKA)
This is a perspective, randomized, blinded study with a parallel design and an allocation ratio of 1 to 1 for the treatment groups to assess the analgesic efficacy of adding the iPACK (injection between the popliteal artery and…
- Trial name
- NCT03703206
- Testing
- ultrasound guided injection of local anesthetic between the popliteal artery and the capsule of the knee (iPACK)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Pennsylvania
Osteo Arthritis Knee
Effects of Blood Flow Restriction Combined With Electrostimulation After Knee Arthroplasty
The goal of this clinical trial is to learn whether blood flow restriction (BFR) combined with electrostimulation (ES) can improve the postoperative course of patients undergoing total knee arthroplasty.
- Trial name
- NCT07141316
- Testing
- Blood flow restriction combined with electrostimulation.
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Pavia
Osteoarthritis
Study Comparing Mini-Incision Versus 2-Incision Approach for Total Hip Replacement
The purpose of the research is to determine if there is a difference between two of the commonly used less invasive techniques (surgical methods that use a smaller incision or cut in the skin) used to perform total hip…
- Trial name
- NCT00594893
- Testing
- Mini Incision Approach, 2 Incision Approach
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Rush University Medical Center
Osteoarthritis,Knee
Efficacy of Multimodal Perioperative Analgesia With Periarticular Drug Injection in Total Knee Arthroplasty(TKA)
The purpose of this study is to compare different medication combinations used in a periarticular injection after total knee replacement surgery(TKR).
- Trial name
- NCT01042093
- Testing
- Ropivacaine, Toradol, Clonidine
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Towson Orthopaedic Associates
Knee Osteoarthritis, Knee Pain Chronic
Dexamethasone for iPACK Block With ACB in Total Knee Arthroplasty
Effect of adding Dexamethasone to Infiltration between the Popliteal Artery and Capsule of the Knee Block with ACB in Patients undergoing Total Knee Arthroplasty
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis
- Trial name
- NCT06470204
- Testing
- Ropivacaine, Ropivacaine+Dexamethasone
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Knee Osteoarthristis, Total Knee Anthroplasty
Prospective, In-Vivo, Post-Market Safety and Efficacy Surveillance Registry of the MAXX Orthopedics, Freedom Total Knee® System
In an effort to satisfy regulatory requirements for post-market surveillance of product safety and efficacy, a representative sample of patients will be recruited for prospective monitoring.
- Trial name
- NCT06627699
- Testing
- Total Knee Arthroplasty
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Maxx Orthopedics Inc
Knee Osteoarthritis
Survival Study of the Genutech® Total Knee Arthroplasty
Prospective cohort sudy of patients undergoing a Genutech® total knee arthroplasty
- Trial name
- NCT06899932
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Hospital de Sant Rafael
Postoperative Anemia, Knee Osteoarthritis
Effect of Preoperative Ferric Carboxymaltose After Simultaneous Bilateral Total Knee Arthroplasty
The primary purpose of this study is to evaluate the safety and efficacy of preoperative intravenous ferric carboxymaltose in patients with anemia undergoing Simultaneous Bilateral Total knee replacement in terms of Quality of…
- Conditions
- Postoperative Anemia, Knee Osteoarthritis, Total Knee Arthroplasty
- Trial name
- NCT03561506
- Testing
- Ferric carboxymaltose, 0.9% Normal Saline
- Volunteers
- 80 people
- Sponsor
- The Catholic University of Korea
Total Shoulder Arthroplasty
Addition of a Pectoserratus Block to Interscalene Block in Patients Undergoing Total Shoulder Replacement
The use of ISB in patients undergoing total shoulder arthroplasty (TSA) is the gold standard and results in significantly reduced pain scores and opioid use.
- Trial name
- NCT06143306
- Testing
- bupivacaine., Saline
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Minnesota
Healthy
Is Standard 3-degree of External Rotation for Posterior Femoral Cut Relevant for Turkish Population
The aim of this study is to evaluate the posterior condylar angle of the distal femur in Turkish population and its concordance with the current standard prosthesis designs used in total knee arthroplasty and to evaluate…
- Trial name
- NCT04355182
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Arthroplasty, Replacement
INHANCE Stemless Reverse Shoulder IDE
2:1 Randomized, Controlled, Multi-Center, Prospective, Pre-Market Study of the INHANCE Stemless Reverse Cementless Total Shoulder.
- Conditions
- Arthroplasty, Replacement, Shoulder
- Trial name
- NCT06323980
- Testing
- Reverse Total Shoulder
- Where
- 15 sites in United States
- Volunteers
- 168 people
- Sponsor
- DePuy Orthopaedics
Total Knee Replacement
Mepivacaine Vs. Bupivacaine Spinal for TKA
This study will enroll patients 18-75 years of age who are undergoing elective primary total knee replacement. The patients will be randomized to receive one of two spinal blocks: 1) mepivacaine or 2) bupivacaine.
- Trial name
- NCT05765682
- Testing
- Mepivacaine Spinal, Bupivacaine Spinal
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Medical University of South Carolina
Shoulder Arthroplasty, Total Shoulder Arthroplasty
A Trial to Assess the Safety and Effectiveness of an Anatomic Total Shoulder System
This study is designed to show that the clinical performance of Mirror Anatomic Shoulder Prosthesis meets the performance of currently marketed device in terms of a composite success endpoint (functional score, radiologic…
- Trial name
- NCT07812324
- Testing
- Mirror Anatomic Total Shoulder Prosthesis, Medacta Anatomic Shoulder
- Where
- 12 sites in United States
- Volunteers
- 286 people
- Sponsor
- Medacta USA
Hip Osteoarthritis
Estimating VO2 Max and Recovery
The study aims to estimate VO2 max levels at pre- and post-operative timepoints before and after hip arthroplasty surgery, using non-exercise-based measurement methods.
- Trial name
- NCT06744582
- Testing
- VO2 max
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- Bournemouth University
Total Knee ArthroplastyKnee Pain, Functionality
Comparison of IPACK Block and PCI for Postoperative Analgesia and Function Recovery Following Total Knee Arthroplasty
It was planned to determine the most effective single and/or combined use in daily use by evaluating the effect on pain control and functional status by combining the posterior capsuler infiltration (PCI) and interspace between…
- Trial name
- NCT05943080
- Testing
- PCI (0.25% marcaine+ 2.0 μg/mL of adrenaline + %0.9 saline), IPACK(0.25% marcaine+ 2.0 μg/mL of adrenaline + %0.9 saline), ACB ( 0.25% marcaine + %0.9 saline)
- Where
- Turkey (Türkiye)
- Volunteers
- 195 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Total Knee Arthroplasty in Geriatric Patients, Spinal Anesthesia
Isobaric Spinal Ropivacaine Versus Hyperbaric Spinal Bupivacaine in Total Knee Arthroplasty in Geriatric Patients
The purpose of this study is to evaluate the efficacy and safety of spinal anesthesia with isobaric ropivacaine, compared with hyperbaric bupivacaine in geriatric patients undergoing lower limb orthopedic surgery.
- Trial name
- NCT02764723
- Testing
- Hyperbaric bupivacaine, Isobaric ropivacaine
- Volunteers
- 52 people
- Sponsor
- Mohamed Sayed Mohamed Abbas
Interphalangeal; Osteoarthritis, Proximal (Bouchard)
Results of the Tactys Implant in Proximal Interphalangeal Joint Arthroplasty
Study at middle term of the functional and radiographic results of proximal interphalangeal joint arthroplasty with the Tactys prothesis. The aim is to evaluate if the short term results are maintained in time.
- Trial name
- NCT04658459
- Testing
- Proximal Interphalangeal Joint Arthroplasty with the Tactys Prosthesis
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Osteoarthritis, Knee
MAKO Total Knee Artroplasty
The purpose of this study is to determine the early clinical and radiographic outcomes of robotically assisted total knee arthroplasty with the MAKO surgical robot using the Triathlon knee system.
- Trial name
- NCT05744895
- Testing
- Device: Robotic MAKO total knee, FocusMotion knee brace, Fitbit tracking device
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Washington University School of Medicine
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