Clinical trials: Arthroplasty
Pain Disorder, Sensory Deficit
Fascia Iliaca Compartment Block For Analgesia After Total Hip Arthroplasty
Introduction Fascia Iliaca compartment block (FICB) is commonly used to treat pain in patients after total hip arthroplasty (THA) despite the lack of RCTs to evaluate the efficacy of FICB for this indication.
- Trial name
- FICB (NCT01758497)
- Testing
- Fascia iliaca compartment block
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Cognitive Change
Cognitive Monitoring in Planned Arthroplasty Surgery
Feasibility study testing a prospective observational methodology to assess the feasibility of serial remote monitoring of cognition with CogTrack™, an online cognitive assessment tool.
- Trial name
- COMPASS (NCT05563597)
- Where
- United Kingdom
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University Hospital Plymouth NHS Trust
Total Hip Arthroplasty (THA)
A Safety Follow Up Study in Australian Subjects Implanted With the SMF Short Modular Femoral Stem Hip System
This is a prospective, single arm, sequential enrolment study to collect relevant clinical and radiological data in approximately 26 subjects, at one site in Australia, who have been implanted with the SMF Short Modular Femoral…
- Trial name
- NCT03646513
- Testing
- SMF Short Modular Femoral Hip System
- Where
- Australia
- Volunteers
- 4 people
- Sponsor
- Smith & Nephew, Inc.
Arthroplasty, Knee Replacement
Survey of Running Following a TKA
The hypothesis of this study is that there are people running following a total knee arthroplasty (TKA). The objective is (1) to determine if there are people that ran/run following their TKA and (2), in case (1) is true, to…
- Trial name
- NCT03848520
- Testing
- TKA
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Brigitte Jolles, MD
Arthroplasty, Replacement, Knee, Rehabilitation
Patient Reported Outcome Measures (PROMs) in Rehabilitation With or Without the Possible Use of a Mobile Application After Primary Knee or Hip Arthroplasty
Rehabilitation after primary knee or hip arthroplasty may include performing exercises with a physiotherapist. For patients who can work well with a computer, tablet or smartphone, it is now possible to use a mobile application…
- Conditions
- Arthroplasty, Replacement, Knee, Rehabilitation, Hip Arthrosis
- Trial name
- NCT04628468
- Testing
- moveUp, Predefined number of traditional physiotherapy sessions
- Where
- 11 sites in Belgium
- Volunteers
- 416 people
- Sponsor
- University Hospital, Ghent
Knee Arthroplasty, Rehabilitation
Effectiveness of Dual Task Training in Total Knee Arthroplasty
This study was planned to investigate the effectiveness of usual care and dual task program in patients who underwent total knee arthroplasty surgery.
- Trial name
- NCT06009380
- Testing
- Physiotherapy and Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Muğla Sıtkı Koçman University
Knee Osteoarthritis
Prospective Randomized Study Comparing the SpheriKA® (MEDACTA) and Origin® (SYMBIOS) Prostheses During Total Knee Replacement Using the Kinematic Alignment Technique
The traditional technique for implanting a total knee prosthesis, known as mechanical alignment, does not aim to preserve the original anatomy and laxity of the knee.
- Trial name
- KAOR (NCT06603103)
- Testing
- SPHERIKA prosthesis, ORIGIN prosthesis
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Clinique du Sport, Bordeaux Mérignac
Coagulation; Intravascular, Rotational Thromboelastometry
The Effect of Tranexamic Acid on Blood Coagulation in Total Hip Arthroplasty Surgery
Total hip arthroplasty (THA) is associated with blood loss ranging from 300 to 2000 mL. Tranexamic acid (TXA) is frequently administered prophylactically during this procedure to reduce blood loss by inhibiting fibrinolysis or by…
- Conditions
- Coagulation; Intravascular, Rotational Thromboelastometry, Fibrinolysis; Hemorrhage, Tranexamic Acid
- Trial name
- NCT03897621
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Thomas Jefferson University
Dysplasia; Hip
Biomechanical Reconstruction of Three Different Hip Stem Designs in Hip Dysplasia Using a 3D CT-based Planning Software
A random population of 200 CT scans of pelvis and thigh in an adult population affected by hip dysplasia will be selected. The aim of this study is to evaluate the biomechanical reconstruction of the hip anatomy provided by three…
- Trial name
- CTdevice (NCT04904640)
- Testing
- Hip stem
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Istituto Ortopedico Rizzoli
Pain
Efficacy, Safety, and Pharmacokinetics of Femoral Nerve Block With EXPAREL in Total Knee Arthroplasty
This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study in 232 adult subjects undergoing primary unilateral TKA under general or spinal anesthesia.
- Trial name
- NCT02713178
- Testing
- bupivacaine liposome injectable suspension
- Where
- 17 sites in United States, Belgium and 1 more
- Volunteers
- 232 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Hip Arthritis, Hip Osteoarthritis
Defining Optimum Cup Orientation for Hip Replacements Taking Into Account the Individual's Anatomy and Movement Patterns
The purpose of this study is to investigate and determine the optimal zone for implanting the cup component (the ball that sits in the joint socket) in a total hip replacement.
- Trial name
- NCT04633525
- Testing
- Optimum Cup Orientation
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- Ottawa Hospital Research Institute
Knee Arthroplasty, Postoperative Complications
Increased Perioperative Communication Program in Knee Arthroplasty
Total knee replacement (TKA) is a surgical procedure to increase the function of the knee joint. However, in the postoperative period, it takes a long time for patients to gain independence and adapt to daily life, and they need…
- Trial name
- NCT06130813
- Testing
- increased perioperative communication program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hacettepe University
Osteoarthritis, Total Knee Arthroplasty
Effectiveness of Passive and Active ROM Exercises Following TKA
The purpose of the study is to determine the effectiveness of new interventional approaches in the early postoperative phase following total knee arthroplasty (TKA).
- Trial name
- NCT02062138
- Testing
- continuous passive motion (CPM), controlled active motion (CAM I), controlled active motion (CAM II)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Rostock
Knee Phenotype Changes After THA, Coronal Plane Alignment of the Knee
Change of Knee Phenotype After Total Hip Arthroplasty
this study evaluates changes in knee phenotype after total hip arthroplasty using radiographic assessment of coronal alignment in a prospective cohort of patients
- Trial name
- THA-KP (NCT07597538)
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Nader Ahmed Sayed Abdelhamed
Pain, Postoperative, Hip Arthroplasty
CMP vs Fascia Iliaca Block
Complete motorsparing protocol (CMP) has been developed to try to minimize the motor nerve block that is created when using Facia iliaca nerve block.
- Trial name
- NCT04426058
- Testing
- CMP, Fascia Illica
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Loyola University
Osteoarthritis: Shoulder
Local Intraoperative Analgesic Injection Versus Single Injection Interscalene Nerve Block in Patients Undergoing TSA
A non-blinded randomized controlled trial, in which participants undergoing primary reverse or total shoulder arthroplasty are randomly assigned to one of two treatment groups.
- Trial name
- NCT02695758
- Testing
- Interscalene brachial plexus block, bupivacaine extended-release liposome injection
- Volunteers
- 156 people
- Sponsor
- Rothman Institute Orthopaedics
Knee Arthropathy, Anatomically Aligned Total Knee Arthroplasty
Comparison of Radiological, Clinical, Functional Outcomes Between Anatomically Aligned Total Knee Arthroplasty and Conventional Total Knee Arthroplasty
Total knee arthroplasty(TKA) is a successful orthopedic surgery with excellent clinical outcome and survival. However, there are concerns about patient satisfaction in previous reports, and dissatisfaction rate of 15-30% is…
- Trial name
- NCT04183985
- Testing
- Total knee arthroplasty prosthesis
- Volunteers
- 100 people
- Sponsor
- The Catholic University of Korea
Revision Total Hip Arthroplasty (RTHA), Revision Total Knee Arthroplasty
CLinical Evaluation of ANtiseptic Skin Preparation in Revision Total Joint Arthroplasty of the Hip and Knee
The goal of this clinical trial is to compare two types of skin preparation solutions (chlorhexidine gluconate-alcohol solution and povidone-iodine solution) that help eliminate harmful bacteria on the skin at the time of surgery…
- Trial name
- CLEANJoint (NCT05828810)
- Testing
- Chlorhexidne Gluconate-Alcohol Skin Preparation, Poviodine-iodine Skin Preparation
- Where
- 3 sites in Canada
- Volunteers
- 400 people
- Sponsor
- Sunnybrook Health Sciences Centre
Osteoarthritis, Patella Resurfacing
Patellar Resurfacing Under Subvastus Approach in Total Knee Arthroplasty
This study aims to compare the clinical results of patella resurfacing or not under subvastus approach in total knee arthroplasty.
- Trial name
- NCT02683460
- Testing
- Patella resurfacing, Patella retention
- Volunteers
- 100 people
- Sponsor
- The Catholic University of Korea
Pain, Shoulder
Continuous Interscalene Block for Same Day Discharge Following Total Shoulder Arthroplasty
Total shoulder surgeries are associated with considerable postoperative pain which may prevent rehabilitation and early discharge from the hospital.
- Trial name
- NCT01785940
- Testing
- Interscalene block
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
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