Clinical trials: Arthroplasty
Total Knee Arthoplasty
Antibiotic Loaded Cement After TKA
This study will provide us with clear information about the postoperative concentration of antibiotic reached in synovial fluid, thereby helping surgeons to determine if concentration could potentially prevent the growth and…
- Trial name
- NCT05429671
- Testing
- total knee arthroplasty, Tobramycin, Gentamicin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Total Knee Anthroplasty
Effect of Combined Adductor Canal and AFCN Block on Postoperative Inflammation
The aim of this thesis is to evaluate the effects of adding an anterior femoral cutaneous nerve (AFCN) block to the adductor canal block used for postoperative analgesia after total knee arthroplasty on the postoperative…
- Trial name
- NCT07367009
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Pain, Postoperative, Hip Osteoarthritis
The Effect of Wrist Ankle Acupuncture on Post-Total Hip Arthroplasty Pain
Total hip arthroplasty is one of the most cost-effective orthopedic surgical procedures which can restore hip function and improve the patient's quality of life.
- Conditions
- Pain, Postoperative, Hip Osteoarthritis, Hip Fractures, Hip Injuries
- Trial name
- NCT06380439
- Testing
- wrist ankle acupuncture
- Where
- 3 sites in Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Elbow Joint Destruction, Post-traumatic Lesions
Clinical Outcomes Study of the Nexel Total Elbow
The objectives of the study are to confirm safety and performance of the Zimmer Nexel Total Elbow when used in primary or revision total elbow replacement.
- Conditions
- Elbow Joint Destruction, Post-traumatic Lesions, Ankylosed Joints, Advanced Rheumatoid Arthritis
- Trial name
- NCT02469662
- Testing
- Nexel Total Elbow
- Where
- 11 sites in United States, Australia and 6 more
- Volunteers
- 134 people
- Sponsor
- Zimmer Biomet
Knee Injuries
Optimized Loading Response by JOURNEY II BCS Knee Increases Daily Physical Activity and Functions
Smith \& Nephew's first edition of the Journey posterior stabilizing total knee arthroplasty was analyzed by the Center for Musculoskeletal Research in a past research study, and it was determined that subjects experienced more…
- Trial name
- NCT02335710
- Testing
- Journey II BCS TKA
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Weight Loss, Pain, Postoperative
Beneficial Side Effects of Topiramate in Obese Patients Undergoing Total Joint Arthroplasty
The purpose of this study is to evaluate the effects of topiramate (TPM) in obese patients with respect to weight loss and pain after total joint replacement surgery
- Trial name
- NCT04613024
- Testing
- Topamax, Gabapentin
- Where
- United States Minor Outlying Islands
- Sponsor
- Stanford University
Total Hip Arthroplasty
Effect of Periprosthetic Fracture on Hip Function After Femoral Neck-preserving Total Hip Arthroplasty
To provide information on reducing the incidence of periprosthetic fractures during hip replacement with the CFP prosthetic stem by analyzing the risk factors for periprosthetic fractures and their effects on hip functional…
- Trial name
- NCT02981823
- Testing
- hip replacement
- Volunteers
- 25 people
- Sponsor
- Hebei Medical University Third Hospital
Glenohumeral Osteoarthritis
Anatomic Versus Reverse Shoulder Arthroplasty for Primary Glenohumeral Osteoarthritis
The primary goal of the investigators prospective randomized study is to determine whether reverse total shoulder arthroplasty (RTSA) have at least as good results as anatomic TSA (non-inferiority), in patients with glenohumeral…
- Trial name
- NCT06513559
- Testing
- Anatomic total shoulder replacement, Reverse total shoulder replacement
- Where
- United States
- Sponsor
- University of Utah
Total Knee Replacement, Virtual Reality Therapy
Effects of Virtual Reality Rehabilitation in Patients With Total Knee Arthroplasty
The aim of this study is to assess the efficacy of virtual rehabilitation through the Virtual Reality Rehabilitation System (VRRS) versus traditional rehabilitation improving the functional outcomes after primary Total Knee…
- Conditions
- Total Knee Replacement, Virtual Reality Therapy, Osteoarthritis, Knee Arthroplasty
- Trial name
- NCT02413996
- Testing
- Kinetec® knee continuous passive motion (CPM ), Functional activities, VRRS rehabilitation
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Osteoarthritis, Rheumatoid Arthritis
A Clinical Investigation of Recovery Following Hip Resurfacing or Total Hip Arthroplasty
The primary purpose of this study is to compare early functional outcomes in patients undergoing hip resurfacing and total hip arthroplasty with the M2a-Magnum™ using more objective measures of function.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Arthritis, Traumatic Arthritis
- Trial name
- NCT00585988
- Testing
- Hip Resurfacing System, M2a-Magnum™ Large Metal Articulation
- Sponsor
- Biomet Orthopedics, LLC
Hip Osteoarthritis, Arthroplasty, Replacement, Hip
Addressing Patients' Expectations of Total Hip Arthroplasty in a Randomized Trial
The goals of this study are to develop and test an educational intervention to address patients' expectations of long-term outcomes of total hip arthroplasty.
- Trial name
- NCT00198003
- Testing
- Educational program to address patients' expectations
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Hospital for Special Surgery, New York
Hip Arthroplasty
Differentiation of Aseptic From Septic Loosening by 18F-fluoride PET
In this study, the investigators utilized the 18F-fluoride PET method to evaluate THA cases with a stable, septic or septic loosened implant in order to differentiate these clinical settings using a novel uptake type…
- Trial name
- NCT01017562
- Where
- Japan
- Volunteers
- 61 people
- Sponsor
- Yokohama City University Medical Center
Osteoarthritis
The Impact of Total Knee Arthroplasty Surgical Technique on Coronal Plane Motion and PatelloFemoral Articulation
The purpose of this study is to examine the impact of two surgical techniques on the outcome of the knee replacement surgery.
- Trial name
- NCT01855906
- Testing
- Gap balanced surgical technique, Measured resection
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Total Shoulder Arthroplasty
Addition of a Pectoserratus Block to Interscalene Block in Patients Undergoing Total Shoulder Replacement
The use of ISB in patients undergoing total shoulder arthroplasty (TSA) is the gold standard and results in significantly reduced pain scores and opioid use.
- Trial name
- NCT06143306
- Testing
- bupivacaine., Saline
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Minnesota
Osteoarthritis, Knee
Quadriceps Exercise Before Total Knee Arthroplasty (The QUADX-1 Trial)
The trial investigates the efficacy of knee-extension exercise prior to total knee replacement. The participants are randomly allocated to one of three exercise dosages. There is no control group.
- Trial name
- QUADX-1 (NCT02931058)
- Testing
- Two knee-extension exercise sessions per week., Four knee-extension exercise sessions per week., Six knee-extension exercise sessions per week.
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Hvidovre University Hospital
Hip Osteoarthritis, Hip Arthroplasty
Collared Versus Collarless Femoral Implants for Total Hip Arthroplasty
This is a randomized control trial that will investigate whether a collared hip replacement implant provides greater stability compared to a collarless option.
- Trial name
- NCT03558217
- Testing
- Collared Femoral Implant, Collarless Femoral Implant
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Arthritis Knee, Pain
The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral TKA
This interventional study aims to compare the effectiveness of local multimodal drug periarticular injection in TKA patients with the standard pain control regime that includes opioids, NSAIDs, and other analgesics.
- Conditions
- Arthritis Knee, Pain, Arthroplasty Complications
- Trial name
- NCT06112548
- Testing
- primary unilateral TKA, Bupivacain, ketorolac
- Where
- Syria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Damascus University
Thromboembolism
Genetics Informatics Trial (GIFT) of Warfarin to Prevent DVT
Blood clots contribute to the death of at least 100,000 Americans each year. Because many of these deaths occur suddenly where treatment is impossible, the best treatment is prevention.
- Trial name
- GIFT (NCT01006733)
- Testing
- Pharmacogenetic, Target INR 1.8
- Where
- 6 sites in United States
- Volunteers
- 1,598 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Congenital Hip Dysplasia, Hip Osteoarthritis
Pelvic Osteotomy Of The Total Hip Replacement
This observational study aims to learn about the outcomes in the previously operated patient and whether pelvic bone rearrangement surgery was a success.
- Trial name
- NCT06209255
- Testing
- Pelvic Osteotomy - Ganz Procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Van Bölge Eğitim ve Araştırma Hastanesi
Hip Arthropathy, Knee Arthropathy
Cryoneurolysis in Patients Awaiting Total Hip and Knee Arthroplasty
During the COVID-19 pandemic, there was a drastic increase in surgical wait times across Canada, notably for patients awaiting total knee and hip arthroplasty.
- Trial name
- NCT06942078
- Testing
- Cryoneurolysis
- Volunteers
- 30 people
- Sponsor
- University of Calgary
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