Clinical trials: Arthroplasty
Arthropathy of Knee Joint
Motion Analysis of EMP Knee Versus Posterior Stabilized Knee Arthroplasty for Osteoarthritis
The purpose of the current study is to analyze and compare the lower-limb joint motions and muscle activation patterns during activities of daily living as well as self reported health related functional outcomes for patients…
- Trial name
- NCT00967161
- Testing
- Total Knee Arthroplasty, Motion analysis
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Osteoarthritis of Hip
Management of Postoperative Pain After Total Hip Arthroplasty
Orthopedic surgery is reportedly among the most painful surgical procedures. Surgical damage following major orthopedic surgery often involves a large, deep incision with considerable tissue dissection and muscle, bone, and…
- Trial name
- NCT01040273
- Testing
- Bupivacaine
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Subscapularis Peel, Morselized Osteotomy
Comparing Two Surgical Methods of Fixation of Subscapularis During Shoulder Arthroplasty
This pilot study is being conducted to compare 2 methods of access to the shoulder for arthroplasty in patients with Osteoarthritis as we do not know has a better outcome.
- Trial name
- NCT00508105
- Testing
- subscapularis peel, osteotomy
- Where
- Canada
- Volunteers
- 87 people
- Sponsor
- Ottawa Hospital Research Institute
Knee Osteoarthritis, Knee Arthroplasty
Feasibility of an Early Home-based Cycling Intervention After Knee Arthroplasty
The goal of this pilot clinical trial is to evaluate whether an early, home-based stationary cycling programme, provided in addition to standard postoperative home exercises, is feasible and acceptable for patients recovering…
- Trial name
- KNEE-CYCLE (NCT07838012)
- Testing
- Early home-based stationary cycling, Usual care: home-based exercise programme
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Central Jutland Regional Hospital
Major Depressive Disorder, Surgery
Intraoperative Ketamine Versus Saline in Depressed Patients Undergoing Anesthesia for Non-cardiac Surgery
This study evaluates whether ketamine, given as part of an anesthetic, improves depression symptoms in depressed patients undergoing non-cardiac surgery.
- Conditions
- Major Depressive Disorder, Surgery, Orthopedic Disorder
- Trial name
- NCT03861988
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Surgery
Comparison Between Kinesiotaping and Cold Therapy After Total Knee Arthroplasty
The investigators aim was to compare the effectiveness of kinesiotaping and cold therapy on muscle strength and functional performance outcomes in patients with TKA during early postoperative period.
- Trial name
- NCT02747901
- Testing
- KINESIOTAPING, COLD THERAPY
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people
- Sponsor
- Dokuz Eylul University
Blood Loss, Surgical
Suction Drainage in the Management of Peri-operative Bleeding in Total and Unicomcompartmental Knee Arthroplasty
Although, suction drainage is routinely used in orthopedic clinical practice, there are still no precise guidelines on its use in total joint arthroplasty, particularly in total as well as unicompartmental knee arthroplasty.
- Trial name
- NCT04508101
- Volunteers
- 153 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Total Knee Arthroplasty for Gonarthrosis
"The Effect of Adductor Canal Block Performed With Postoperative Thigh Tourniquet Application on Pain After Total Knee Arthroplasty"
The biggest fear for patients undergoing knee replacement surgery is that persistent pain felt at the back of the knee postoperatively.
- Trial name
- NCT07539467
- Testing
- Tourniquet-Assisted Adductor Canal Block (T-ACB) grou, Standard Adductor Canal Block (S-ACB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Arthroplasty, Replacement, Knee, Knee Arthroplasty, Total
Posterior Cruciate Retaining (PCR) Versus Posterior Cruciate Substituting (PCS) Total Knee Arthroplasty (TKA)
This randomized clinical trial (RCT) examined 10 year outcomes comparing SCORPIO™ Posterior Cruciate Substituting (PCS) versus Posterior Cruciate Retaining (PCR) Total Knee Arthroplasty (TKA) as the primary outcome.
- Trial name
- SCORPIO™ (NCT02429856)
- Testing
- SCORPIO™
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Alberta
Acute Pain
Study to Examine Pain Relief With Supplemental Intrathecal Morphine in TKA Patients
This is a prospective, randomized, double-blinded, placebo-controlled study designed to examine pain relief following intrathecal morphine sulfate (0.2mg) in patients undergoing total knee arthroplasty (TKA) under spinal…
- Trial name
- NCT02620631
- Testing
- Morphine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Stony Brook University
Adrenal Cortex Hormones, Arthroplasty, Replacement, Knee
Comparing Different Doses of Corticosteroids in Local Infiltration Analgesia (LIA) for Total Knee Arthroplasty
This study aims to compare the efficacy of different doses of glucocorticoids in local infiltration analgesia (LIA) during total knee arthroplasty (TKA) through a prospective single-center randomized controlled trial, and to…
- Conditions
- Adrenal Cortex Hormones, Arthroplasty, Replacement, Knee, Anesthesia, Local
- Trial name
- NCT07337772
- Testing
- LIA with different doses of Diprospan
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Hip Arthropathy
Prediction of the Collapse of Necrotic Femoral Head Using Computed Tomography Scan and X-ray Before Hip Arthroplasty
To verify that CT scan and X-ray can predict the collapse of the necrotic femoral head before hip arthroplasty and effectively guide the surgical management.
- Trial name
- NCT03351153
- Testing
- X-ray, CT, specimen
- Volunteers
- 86 people
- Sponsor
- Hebei Medical University Third Hospital
Primary Osteoarthritis, Post-Traumatic Arthritis
AVANTAGE® RELOAD Double Mobility Acetabular Cup -Clinical Study
This is a Post Marketing Clinical Follow Up study (PMCF) on the AVANTAGE RELOAD dual mobility system cup.
- Conditions
- Primary Osteoarthritis, Post-Traumatic Arthritis, Inflammatory Joint Disease, Femoral Neck Fracture
- Trial name
- NCT03357445
- Testing
- Avantage Reload cup
- Where
- 4 sites in France, Slovenia
- Volunteers
- 500 people
- Sponsor
- Zimmer Biomet
Rehabilitation
Postoperative Rehabilitation After Knee Arthroplasty: Anti-Gravity Treadmill
The aim of this study is to clarify the effectiveness and the usefulness of the anti-gravity treadmill in postoperative rehabilitation after knee arthroplasty.
- Trial name
- NCT03904030
- Testing
- Rehabilitation with or without Anti-Gravity Treadmill
- Where
- Finland
- Volunteers
- 62 people
- Sponsor
- Orton Orthopaedic Hospital
Knee Arthroplasty, Rehabilitation
Effectiveness of Dual Task Training in Total Knee Arthroplasty
This study was planned to investigate the effectiveness of usual care and dual task program in patients who underwent total knee arthroplasty surgery.
- Trial name
- NCT06009380
- Testing
- Physiotherapy and Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Muğla Sıtkı Koçman University
Arthroplasty, Replacement
Study to Evaluate the Safety and Effectiveness of the REAL INTELLIGENCE™ CORI™ in Total Knee Arthroplasty (TKA) Procedure
Background: REAL INTELLIGENCE™ CORI™ (CORI Robotics) is a computer-assisted orthopaedic surgical navigation and burring system. CORI Robotics is designed to help surgeons in planning and executing certain types of knee surgery…
- Conditions
- Arthroplasty, Replacement, Knee
- Trial name
- CORI RCT TKA (NCT04848896)
- Testing
- CORI Robotics, Conventional Procedure
- Where
- 4 sites in Australia, China and 2 more
- Volunteers
- 140 people
- Sponsor
- Smith & Nephew, Inc.
Total Knee Arthroplasty, Dual Task Exercises
The Effects of Dual-Task Exercises on Parameters After Total Knee Arthroplasty
Introduction: Total knee arthroplasty (TKA) is a widely used surgical treatment method worldwide for advanced pain and functional loss resulting from osteoarthritis and other degenerative knee pathologies.
- Trial name
- NCT07416877
- Testing
- Home Exercises, Dual Task Exercises
- Volunteers
- 40 people
- Sponsor
- Yuzuncu Yil University
Osteoarthritis, Knee
Finnish Unicompartmental and Total Knee Arthroplasty Investigation
Unicondylar knee arthroplasty (UKA) can be used as the treatment of knee OA isolated to a single compartment instead of TKA. Both UKA and TKA have been used for decades as a treatment of knee OA.
- Trial name
- FUNCTION (NCT02481427)
- Testing
- Unicondylar Knee Replacement, Total Knee Replacement
- Where
- 3 sites in Finland
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
CMC-1 Osteoarthritis, Trapeziometacarpal Osteoarthritis
Pyrocardan® Implant Arthroplasty or LRTI for Trapeziometacarpal Osteoarthritis
This is a randomized controlled trial comparing the Pyrocardan® implant (intervention group) with the standard ligament reconstruction and tendon interposition (LRTI) (control group).
- Trial name
- NCT06290986
- Testing
- Pyrocardan® implant, Ligament reconstruction and tendon interposition (LRTI)
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Herlev and Gentofte Hospital
Arthroplasty, Replacement, Hip, Exercise Therapy
Walking Skill Training Program Effects in Patients With Total Hip Arthroplasty
Rehabilitation plays an important part after total hip arthroplasty. In this common practice few studies have been performed on this issue. The aims of this study were: 1.
- Trial name
- NCT00808483
- Testing
- Walking skill training program
- Where
- Norway
- Volunteers
- 68 people
- Sponsor
- University of Oslo
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