Clinical trials: Arthroplasty
Total Knee Arthroplasty
Comparison Of Outcomes After Knee Arthroplasty Using Posterior-Substituting Versus Cruciate-Retaining Prostheses
Total knee replacement is used in the treatment of patients with knee arthritis, rheumatoid arthritis and other knee disorders. Today, there are basically two designs; It cuts the posterior cruciate ligament (PS) and protects the…
- Trial name
- NCT06170931
- Testing
- posterior cruciate ligament-retaining prostheses, posterior cruciate ligament-substituting prostheses
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Bezmialem Vakif University
Knee Osteoarthritis, Knee Arthritis
ROMTECH PortableConnect Rehabilitation Device Usage Post Unilateral Total Knee Arthroplasty (TKA)
ROMTech is focused on transforming the healthcare market by delivering lower extremity rehabilitation systems that are effective, efficient for patient use, cost-effective, and provide better patient outcomes while simultaneously…
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Disease
- Trial name
- NCT04497129
- Testing
- ROMTech PortableConnect, Traditional Rehabilitation and CPM Device
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- ROM Technologies, INC
Shoulder Osteoarthritis
Comparison Between Anatomic Shoulder Arthroplasty, Hemiarthroplasty, and Reverse Shoulder Arthroplasty.
This study aims to evaluate outcomes in patients over 70 years of age who underwent anatomic shoulder arthroplasty, hemiarthroplasty, or reverse shoulder arthroplasty, focusing on revision rates, rotator cuff integrity as primary…
- Trial name
- NCT07060469
- Volunteers
- 110 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Anxiety, Opioid Use
Effects of Hypnosis Therapy on Outcomes in Total Knee Replacement
The purpose of this study is to collect information to evaluate the role of the psychogenic component of pain induced by anxiety on postoperative outcomes in major orthopaedic surgery and to determine whether hypnosis therapy…
- Trial name
- NCT05818969
- Testing
- Hypnosis Therapy
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Foundation for Orthopaedic Research and Education
Hip Osteoarthritis, Arthroplasty Complications
DELTA Multihole TT Study
A retrospective study evaluating clinical and radiographic early outcomes of total hip arthroplasty and revision hip arthroplasty with DELTA Multihole TT cup.
- Conditions
- Hip Osteoarthritis, Arthroplasty Complications, Hip Dysplasia
- Trial name
- NCT04375345
- Testing
- hip arthroplasty
- Where
- Slovakia
- Volunteers
- 40 people
- Sponsor
- University Hospital Bratislava
Total Hip Arthroplasty
Total Hip Arthroplasty (THA) Lumbar Plexus Verses Periarticular
Total hip arthroplasty is a one of the most commonly performed surgical procedures with increasing numbers anticipated over the next several decades.
- Trial name
- NCT02242201
- Testing
- PNB Bupivacaine, PAI Ropivacaine, PAI liposomal bupivacaine
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Osteoarthritis (OA) of the Knee, Fracture
LinkSymphoKnee (LSK) Total Knee Replacement System Study - Ultra-congruent (UC)
To collect information about implant performance and patient clinical outcomes in patients undergoing primary total knee arthroplasty with the LinkSymphoKnee total knee replacement system with ultra-congruent tibial bearing…
- Conditions
- Osteoarthritis (OA) of the Knee, Fracture, Rheumatoid Arthritis
- Trial name
- NCT06670651
- Testing
- total knee arthroplasty device
- Where
- 2 sites in United States
- Volunteers
- 600 people
- Sponsor
- LinkBio Corp.
Pain
Pain Control After Total Knee Arthroplasty: Benefit In Adding Single Shot Adductor Canal Block to Existing Pain Regimen Protocol?
This is a randomized, double blinded, standard of care controlled clinical trial. All adult patients over eighteen desiring total knee arthroplasty will be eligible.
- Trial name
- NCT02740192
- Testing
- Adductor Canal Block, Periarticular Injection, Ropivacaine
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Henry Ford Health System
Anterior Cruciate Ligament Reconstruction
Dry Needling Effectiveness of Patients on Break Anterior Cruciate Ligament.
We will conduct a randomized clinical trial observing forty patients divided into two groups: one group composed of twenty individuals undergoing surgery for ruptured ACL, which perform dry needling of myofascial trigger (PGM)…
- Trial name
- ACL (NCT02699411)
- Testing
- Dry needling, Stability and propioception
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- European University Spain
Shoulder Arthritis, Shoulder Osteoarthritis
S-11 SMR TT Hybrid Glenoid and Cementless Finned Short Stem
Post-market, prospective, non randomized, open label, multicentre, clinical study analysing outcomes of shoulder arthroplasty with SMR TT Hybrid Glenoid with or without SMR Cementless Finned Short Stem
- Conditions
- Shoulder Arthritis, Shoulder Osteoarthritis, Arthrosis, Osteoarthritis
- Trial name
- NCT05314387
- Testing
- SMR TT Hybrid Glenoid without Cementless Finned Short Stem, SMR TT Hybrid Glenoid with Cementless Finned Short Stem
- Volunteers
- 100 people
- Sponsor
- Limacorporate S.p.a
Total Knee Replacement, Knee Arthroplasty
Yale Steroid Enhanced Versus Exparel Nerveblock TKA RCT Study
The objective of this phase 2 study is to investigate the efficacy of Dexamethasone sodium phosphate (DEX) plus Methylprednisolone acetate (MPA) in combination with plain bupivacaine (B) compared with Liposomal Bupivacaine (LB)…
- Trial name
- Yale SEVEN (NCT05279092)
- Testing
- Bupivacaine-Liposomal Bupivacaine, Bupivacaine -Dexamethasone Sodium Phosphate-Methylprednisolone Acetate
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Yale University
Total Knee Arthroplasty
BFRT vs Standard PT After Total Knee Arthroplasty
Background Blood flow restriction training (BFRT) uses a specialized tourniquet system to restrict arterial inflow and venous outflow to the limb during low-load resistance exercise.
- Trial name
- BFRT-TKA (NCT04366336)
- Testing
- Blood Flow Restriction Training, Standard Physical Therapy
- Where
- United States
- Sponsor
- Norton Healthcare
Foramen Ovale, Patent, Delirium
Patent Foramen Ovale and the Risk of Postoperative Delirium Following Elective Hip and Knee Arthroplasty Surgeries
This study will involve patients who are planned to have hip or knee replacement surgeries. They will undergo a Transthoracic Echocardiogram study (an ultrasound of the heart) to look for a Patent Foramen Ovale (PFO).
- Conditions
- Foramen Ovale, Patent, Delirium, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Trial name
- NCT02400892
- Testing
- TTE Bubble Study
- Where
- Canada
- Volunteers
- 226 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pain, Postoperative Pain
PENG Block Plus Lateral Femoral Cutaneous Nerve Block for Posterolateral-approached Total Hip Arthroplasty
This study aims to analyze the effect of Pericapsular Nerve Group (PENG) Block combined with lateral femoral cutaneous nerve block vs.
- Conditions
- Pain, Postoperative Pain, Acute Pain, Analgesia
- Trial name
- PENG-FLAT (NCT05432011)
- Testing
- PENG Block, Lateral Femoral Cutaneous Nerve Block, Wound Infiltration
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Campus Bio-Medico University
Arthroplasty, Replacement, Knee
Fast Track Total Knee Arthroplasty: Local Infiltration Analgesia vs Femoral Nerve Block
The objective of this study is to determine whether either a femoral nerve block (FNB) or local infiltration analgesia (LIA) is a better anesthetic technique to achieve optimal functional outcome after one year in patients…
- Trial name
- NCT01966263
- Testing
- LIA of the posterior capsule of the knee, LIA of the anterior capsule of the knee, LIA of the subcutaneous tissue of the knee
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Sint Maartenskliniek
Osteoarthritis, Knee
Total Knee Arthroplasty (TKA) Cemented Versus Cementless
The aim of the study is to analyse and to compare the quality of fixation of a femoral implant with or without cement. One hundred thirty patients will be operated on and included with 2 groups, the first one with TKA all…
- Trial name
- NCT00132587
- Testing
- cement Palacos R40 and LV40
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Hospices Civils de Lyon
Knee Osteoarthritis
Race and Preference for Knee Replacement: A Patient-Centered Intervention
A randomized, controlled design will be utilized to examine and compare the effectiveness of the proposed educational intervention, which includes a combination of an educational decision aid and motivational interviewing with…
- Trial name
- REPAIR (NCT02413411)
- Testing
- DA/MI Intervention, an educational program (an NIH-developed booklet)
- Where
- United States
- Volunteers
- 493 people
- Sponsor
- University of Pennsylvania
Osteo Arthritis Knee
Utilization of a Knee Brace With Extension Swing
The purpose of this research is to help determine if use of the Guardian brace during prehab and post-op rehab after TKA can help improve functional outcomes and reduce the incidence of post-operative flexion contractures which…
- Trial name
- NCT05179044
- Testing
- Guardian Sport Rehabilitator knee brace
- Where
- United States
- Sponsor
- NYU Langone Health
Osteoarthritis, Knee
Postoperative Pain Control Results Using Periarticular Versus Intra-capsular Injection of Bupivacaine Liposome Injectable Suspension in Total Knee Arthroplasty
The purpose of this study is to determine quantitative and qualitative differences in post-operative pain relief for patients undergoing primary total knee arthroplasty (TKA) who receive administration of a newly approved, long…
- Trial name
- NCT02166632
- Testing
- Intracapsular Injection, Periarticular Injection
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Broward Health
Osteoarthritis of the Knee
Patient Specific Instrumentation in TKR
This is a randomised control trial to assess the benefits of using patient specific instrumentation in total knee replacement surgery.
- Trial name
- NCT02096393
- Testing
- Zimmer Patient specific instruments, Standard instrumentation
- Where
- 2 sites in United Kingdom
- Volunteers
- 72 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.