Clinical trials: Arthroplasty
Knee Arthroplasty, Total, Analgesia
Shared Decision Aid for Post-Total Knee Arthroplasty Opioid Prescribing
This will be a randomized controlled clinical trial in patients who have undergone primary unilateral total knee arthroplasty at Brigham and Women's Faulkner Hospital, Brigham and Women's Hospital and University of Chicago…
- Conditions
- Knee Arthroplasty, Total, Analgesia, Opioid Use, Unspecified
- Trial name
- NCT04564729
- Testing
- Shared Decision Making
- Where
- 2 sites in United States
- Volunteers
- 142 people
- Sponsor
- Brigham and Women's Hospital
Developmental Dysplasia of the Hip, Acetabular Bone Loss
3D-Printed Pelvic Models for Planning Complex Total Hip Arthroplasty
Total hip arthroplasty (THA) in patients with complex acetabular anatomy can be challenging because of abnormal bone structure, deformity, or bone loss.
- Conditions
- Developmental Dysplasia of the Hip, Acetabular Bone Loss, Acetabular Fracture
- Trial name
- NCT07904637
- Testing
- Conventional Imaging-Based Preoperative Planning, CT-Based 3D-Printed Pelvic Model-Assisted Planning
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Ain Shams University
Osteoarthritis
Outcomes Following Tourniquet and Non-Tourniquet Assisted Total Knee Arthroplasty
The overall goal of this study is to determine the effects of intraoperative tourniquet use during total knee arthroplasty (TKA), compared to TKA without the use of a tourniquet (NOTQT), for strength and functional recovery…
- Trial name
- NCT02203045
- Testing
- Total Knee Arthroplasty
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- University of Colorado, Denver
Ankle Arthroplasty, Prosthesis User
3D X-ray Motion Analysis of Ankle-foot Motion After Total Ankle Arthroplasty
Patients who have had a total ankle joint replacement surgery typically have limited movement in their ankles possibly due to the fact that commonly used ankle joint prosthetic devices only allow limited axes of motion.
- Conditions
- Ankle Arthroplasty, Prosthesis User, Joint Disease
- Trial name
- NCT03575975
- Testing
- Total Ankle Replacement Prosthesis
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Pain, Acute, Hip Arthropathy
Safety of Ibuprofen After Major Orthopaedic Surgeries
Safety of an eight-day treatment with ibuprofen after primary hip and knee arthroplasties.
- Conditions
- Pain, Acute, Hip Arthropathy, Knee Arthropathy, Safety Issues
- Trial name
- PERISAFE (NCT05575700)
- Testing
- Ibuprofen
- Where
- 11 sites in Denmark
- Volunteers
- 2,904 people
- Sponsor
- Naestved Hospital
Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery, Osteoarthritis (OA) of the Knee
Does the Use of Patient Specific Instrumentation Improve Outcomes in Knee Arthroplasty Surgery for Osteoarthritis When Compared to Standard Posterior Referenced Instrumentation?
The goal of this randomized study is to see if using patient-specific instruments (PSI) during total knee replacement surgery improves outcomes compared to standard instruments.
- Trial name
- PRIPSI (NCT06720012)
- Testing
- Patient specific instrumentation (PSI), Conventional instruments, Cemented Total Knee Arthroplasty
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Vastra Gotaland Region
Knee Arthroplasty
Rehabilitation After Fast-track Total Knee Arthroplasty
BACKGROUND In 2008 approximately 7,700 total knee arthroplasties (TKA) were performed in Denmark. The results after TKA is in general very good, the investigators have, however, discovered that patients following fast-track TKA…
- Trial name
- HOLEST (NCT01329081)
- Testing
- Postoperative rehabilitation after fast-track TKA
- Where
- Denmark
- Sponsor
- University of Aarhus
Osteoarthritis
Comparison of Femoral Nerve Catheter and Adductor Canal Block With Steroid Adjuvant in Total Knee Replacement (TKR)
We hypothesize continuous adductor canal block with steroid adjuvant would offer no inferior analgesics and rehabilitation ability than continuous femoral nerve block for postoperative patients receiving total knee arthroplasty.
- Trial name
- NCT01973530
- Testing
- adductor canal block, femoral nerve block
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Queen Elizabeth Hospital, Hong Kong
Total Hip Arthroplasty
Effect of Periprosthetic Fracture on Hip Function After Femoral Neck-preserving Total Hip Arthroplasty
To provide information on reducing the incidence of periprosthetic fractures during hip replacement with the CFP prosthetic stem by analyzing the risk factors for periprosthetic fractures and their effects on hip functional…
- Trial name
- NCT02981823
- Testing
- hip replacement
- Volunteers
- 25 people
- Sponsor
- Hebei Medical University Third Hospital
Anesthesia, Local
Serum Bupivacaine Concentration Levels After Injection of Liposomal Bupivacaine Into the Knee
Serum levels of bupivacaine over time after peri-articular injection of a mixture of liposomal bupivacaine and plain bupivacaine during total knee arthroplasty.
- Trial name
- NCT02626559
- Testing
- liposomal bupivacaine/plain bupivacaine peri-articular injection
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Utah
Knee Osteoarthritis, Degenerative Joint Disease of the Knee
Patient Outcomes Following Kinematic and Functional Alignment in Robotic-Assisted Total Knee Arthroplasty With Randomized Insert Types
This study aims to evaluate patient outcomes following robotic-assisted total knee arthroplasty using the VELYS system. Patients undergoing surgery will receive either kinematic alignment or functional alignment as determined by…
- Trial name
- VELYS RCT (NCT07533188)
- Testing
- Medial Stabilized Insert, Cruciate Retaining Insert
- Where
- Singapore
- Volunteers
- 240 people
- Sponsor
- Singapore General Hospital
Osteo Arthritis Knee
Cryo and Compression Therapy After TKA and UKA
The goal of this clinical trial is to test the use of a cold and compression brace during the first 6 weeks after surgery in patients who had a total or partial knee replacement.
- Trial name
- NCT05572359
- Testing
- cryo-and compression brace
- Where
- Netherlands
- Volunteers
- 208 people
- Sponsor
- Martini Hospital Groningen
Hip Arthropathy
Lumbar Plexus-sciatic Nerve Block With Sevoflurane on Cognitive Function in Elderly Patients After Hip Arthroplasty
To assume that lumbar plexus-sciatic nerve block combined with sevoflurane can effectively diminish the incidence of cognitive dysfunction in elderly patients after hip arthroplasty.
- Trial name
- NCT03162861
- Testing
- sevoflurane inhalation for anesthesia, propofol for anesthesia
- Volunteers
- 70 people
- Sponsor
- Qinghai University
Cuff Tear Arthropathy, Primary Osteoarthritis
Follow-up Evaluating Clinical and Radiological Outcomes of Total Shoulder Arthroplasty With Permedica's MIRAI Prosthesis
This observational study is conducted in order to evaluate the effectiveness of the primary total shoulder arthroplasty with the Permedica's MIRAI Modular Shoulder Prosthesis System on the general population of patients who are…
- Conditions
- Cuff Tear Arthropathy, Primary Osteoarthritis, Secondary Osteoarthritis, Shoulder Osteoarthritis
- Trial name
- NCT05128500
- Testing
- Total Shoulder Arthroplasty with Permedica's MIRAI
- Where
- 4 sites in Germany, Italy and 1 more
- Volunteers
- 76 people
- Sponsor
- Permedica spa
Hip Replacement Arthroplasty
Determination of Metal Ion Serum Levels and Cytokines in Total Hip Replacement
The goal of the study is the analysis of metal ion serum concentrations and of the cytokine production in the blood of patients with a conventional cementless total hip replacement.
- Trial name
- NCT01394744
- Where
- 2 sites in Germany
- Volunteers
- 30 people
- Sponsor
- Ludwig-Maximilians - University of Munich
ERAS, Knee Osteoarthritis
Enhanced Recovery After Surgery Protocols in Total Knee Arthroplasty Via Midvastus Approach
The study aimed to investigate the impact of enhanced recovery after surgery (ERAS) protocols on the clinical effect of total knee arthroplasty (TKA) via the midvastus approach
- Trial name
- NCT04873544
- Testing
- ERAS protocols for TKA
- Where
- China
- Volunteers
- 69 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Total Hip Arthroplasty
TRJ Post Market Clinical Follow Up
Clinical and radiological 2 years results of TRJ® Hip Stem.
- Trial name
- NCT02019862
- Testing
- TRJ® Total Hip Arthroplasty
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Aesculap AG
Unilateral Primary Osteoarthritis, Left Knee
Benefits of Early Proprioceptive Re-education Without Visual Information After Total Knee Arthroplasty
Osteoarthritis is a common and disabling joint disease, affecting 4.7% of men and 6.6% of women in France. It causes pain and impaired joint mobility, as well as a reduction in proprioception due to damage to intra-articular…
- Trial name
- RAPPEL (NCT06936267)
- Testing
- rehabilitation : eyes closed, rehabilitation : eyes open
- Where
- 2 sites in France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Rouen
Knee Osteoarthritis
RF TKA Prehabilitation
The purpose of this study is to compare the effects of the radiofrequency applied to the sensory innervation of the knee, with respect to a control group (standard therapy), in a prehabilitation program aiming to improve the…
- Trial name
- NCT03758300
- Testing
- Radiofrequency
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Knee Osteoarthritis
Comparison Between Medial Pivot Versus Symmetric Insert Total Knee Arthroplasty
The functional outcome and longevity of total knee arthroplasty (TKA) is still a concern. Despite various developments in TKA designs, including fixed or mobile bearing, cruciate retaining or posterior stabilized, multi or single…
- Trial name
- NCT04769544
- Testing
- total knee arthroplasty with medial pivot tibial insert or symmetrical insert
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Elda University Hospital