Clinical trials: Arthroplasty
Rhematoid Arthritis, Osteo Arthritis of the Knee
Persona SoluTion PPS Femur PMCF
The goal of this study is to generate clinical evidence and evaluate the safety and performance of the Persona® SoluTion® PPS Femurs in the US market, with data supporting global regulatory submissions, including CE marking under…
- Conditions
- Rhematoid Arthritis, Osteo Arthritis of the Knee, Traumatic Arthritis of Knee (Diagnosis), Polyarthritis
- Trial name
- NCT07286513
- Testing
- Total knee arthroplasty
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Zimmer Biomet
Osteoarthritis Of Knee
Feasibility of Outpatient Total Knee Arthroplasty
This proposal outlines the investigators plan to develop, evaluate and implement an accelerated in hospital and community rehabilitation following total knee arthroplasty (TKA) leading to outpatient TKA.
- Trial name
- NCT01186211
- Where
- Canada
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Total Knee Arthroplasty
Comparison of Intraoperative Warming Devices
The sublingual (under the tongue) core temperature within 10 minutes of arrival in the post anesthesia care unit (PACU) for patients warmed with the Dynatherm vitalHeat2 (VH2) System under general anesthesia for total knee…
- Trial name
- NCT00711867
- Testing
- VH2, Bair Hugger
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Mayo Clinic
Periprosthetic Joint Infection (PJI), Periprosthetic Knee Infection
Analysis of the Etiopathogenesis of Postoperative Complications in Orthopedic Patients Using Knee and Hip Arthroplasty as an Example
Relevance and Rationale Due to the widespread development of high-tech medical care in traumatology and orthopedics for patients with severe forms of hip and knee osteoarthritis and aseptic necrosis, and the increasing number of…
- Conditions
- Periprosthetic Joint Infection (PJI), Periprosthetic Knee Infection, Periprosthetic Hip Infection, Diagnostic
- Trial name
- NCT07813832
- Where
- Russia
- Volunteers
- 750 people
- Sponsor
- People's Friendship University of Russia
Knee Osteoarthritis
Clinical Outcome After Total Knee Arthroplasty Using CR or PS Inlay
Compare knee flexion after cruciate-retaining and cruciate substituting Total Knee Arthroplasty.
- Trial name
- NCT03873363
- Testing
- PS TKA, CR TKA
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Technische Universität Dresden
Infected of Hip or Kneeprosthesis
β-lactam Use in Single-stage Exchange of ProstheTic Infections (Knee / Hip) in a Center of Reference (β-SEPTIC)
According to the official recommendations, infected prosthesis can be surgically treated by one or two-stage replacement. In Strasbourg, the investigators only perform one-stage surgery, which means that the new materiel is put…
- Trial name
- β-SEPTIC (NCT04123964)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Total Knee Anthroplasty
Comparison of Ultrasound-Guided Lumbar ESPB and ACB for Knee Arthroplasty
Total knee arthroplasty (TKA) is a surgical procedure frequently associated with moderate-to-severe postoperative pain. While Adductor Canal Block (ACB) has demonstrated analgesic efficacy in TKA, the Erector Spinae Plane Block…
- Trial name
- NCT07115771
- Testing
- Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Knee Surgery With Tourniquet
Effect of Spinal or Sevoflurane Anesthesia on Neutrophil Activation During Knee Surgery With Pneumatic Tourniquet
Aim of study : Assessement of neutrophil activation during ischemia reperfusion associated with tourniquet use for total knee arthroplasty.
- Trial name
- NCT03470363
- Testing
- Sevoflurane Volatile Liquid, Bupivacaine / SUFentanil
- Volunteers
- 40 people
- Sponsor
- University of Liege
Osteoarthritis of the Shoulder
TSA vs RSA in Glenohumeral Osteoarthritis
This study will compare total shoulder arthroplasty (TSA) reverse shoulder arthroplasty (RSA) procedures, in the context of a prospective, randomized-controlled trial to determine the optimal treatment in patients 65 years of age…
- Trial name
- SERVASA (NCT04228419)
- Testing
- Total Shoulder Arthroplasty, Reverse Shoulder Arthroplasty
- Where
- 4 sites in Canada
- Volunteers
- 108 people
- Sponsor
- Ottawa Hospital Research Institute
Knee Osteoarthritis
Pre-emptive Effect of Duloxetine in the Second Knee in Staged Total Knee Arthroplasty
In Korea, the interval between knee arthroplasties is usually 1 week. According to previous studies, when total knee arthroplasty was performed at 1-week intervals, total bleeding was reduced and the period of hospital stay was…
- Trial name
- NCT03792828
- Testing
- Duloxetine HCl 30mg
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Hip Arthropathy, Fasting
The Effect of Oral Carbohydrate Solution on Anxiety and Comfort in Patients Undergoing Hip Arthroplasty
Surgical interventions are not only a physiological trauma, but also a psychological and social trauma because they cause deterioration of the individual's comfort.
- Conditions
- Hip Arthropathy, Fasting, Patient Comfort
- Trial name
- NCT05134207
- Testing
- oral carbohydrate solution
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Nevsehir Haci Bektas Veli University
Total Knee Arthroplasty, Knee Arthroplasty
Risk of Serious Adverse Events Following Unsupervised vs Supervised Rehabilitation After Knee Arthroplasty
SUMMARY Background: After knee arthroplasty (KA), rehabilitation is widely recommended, yet its clinical effectiveness-especially the need for supervision-has been challenged.
- Conditions
- Total Knee Arthroplasty, Knee Arthroplasty, Unicompartmental Knee Arthroplasty
- Trial name
- SAFE-T (NCT07067060)
- Volunteers
- 40,000 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Total Knee Arthroplasty
The Analgesic Effect of Nitroglycerin Patch for Postoperative Pain After Total Knee Replacement
Patients who undergo general anestheesia for total knee arthroplasty pften have sever postoperative pain which hinders their rehabilitation.
- Trial name
- NCT00375362
- Testing
- Nitroderm patch
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Arthroplasty, Replacement, Knee, Chronic Pain Post-Proceduraal
The Effect of Regional Anaesthesia and Genetic Factors in the Development of Chronic Pain Following Total Knee Arthroplasty
The study aims to assess the effect of spinal anaesthesia against a general anaesthesia with a femoral block, with respect to the incidence of chronic pain following a total knee replacement.
- Trial name
- NCT04206046
- Testing
- Spinal anaesthesia, General anaesthesia
- Where
- Malta
- Volunteers
- 200 people
- Sponsor
- Sciberras, Stephen M.D.
Gonarthrosis, Total Knee Arthroplasty
Infiltration or Nerve Blocks in Addition to Adductor Canal Block
The aim of this study is to evaluate the analgesic efficacy of this quadruple sensory block compared with the currently recommended procedure (adductor canal block + infiltration).
- Trial name
- INCA (NCT06920186)
- Testing
- Analgesia
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Effects of Preoperative Education, and Follow-up Sessions of Patients With Total Hip and Knee Arthroplasty (ESIPPES)
The shortening of the length of stay implies rethinking the perioperative management (around the operative period), which precedes and immediately follows the operation, in order to ensure a good preparation of the patient and an…
- Trial name
- ESIPPES (NCT05452161)
- Testing
- Control group, Intervention group A, Intervention group B
- Where
- Switzerland
- Volunteers
- 163 people
- Sponsor
- Haute Ecole de Santé Vaud
Postoperative Pain
Preopioid Versus Nonopioid in Total Knee Arthroplasty (TKA)
Observational study evaluating pain response after total knee arthroplasty (TKA) in patients taking strong, weak or no opioids preoperatively.
- Trial name
- NCT01323179
- Where
- 4 sites in Denmark
- Volunteers
- 140 people
- Sponsor
- Hvidovre University Hospital
Hip Osteoarthritis, Joint Diseases
Robotic Total Hip Arthroplasty Anesthesia Management
Robotic arthroplasty is increasing in acceptance on a global scale as a result of advancements in orthopedic surgery technology.
- Conditions
- Hip Osteoarthritis, Joint Diseases, Anesthesia
- Trial name
- NCT05794282
- Testing
- the robot assisted total hip arthroplasty, the conventional total hip arthroplasty
- Volunteers
- 150 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
HIP AND KNEE OSTEOARTHRITIS
Prepare II - Predictive Model Training and External Validation
The general aim of the project is training and testing a predictive model of inpatient rehabilitation stay after hip and knee replacement for osteoarthritis.
- Trial name
- NCT07304323
- Testing
- Functional rehabilitation
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Osteoarthritis Shoulder, Rheumatoid Arthritis
Exactech Humeral Reconstruction Prosthesis of Shoulder Arthroplasty PMCF (HRP)
The objective of this study is to collect and evaluate long-term clinical outcomes data in order to better understand the safety and performance of the Equinoxe Humeral Reconstruction Prosthesis in shoulder arthroplasty over…
- Conditions
- Osteoarthritis Shoulder, Rheumatoid Arthritis, Oncology
- Trial name
- HRP (NCT05615246)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Exactech