Clinical trials: Arthroplasty Shoulder
Osteo Arthritis Shoulders, Avascular Necrosis of the Head of Humerus
Easytech Reversed Shoulder System Clinical Study
The purpose of the study is to collect data to demonstrate the safety and effectiveness of the Easytech Reversed Shoulder System for the treatment of patients who require a reverse total shoulder arthroplasty.
- Conditions
- Osteo Arthritis Shoulders, Avascular Necrosis of the Head of Humerus, Rotator Cuff Tear
- Trial name
- NCT03806842
- Testing
- Easytech group
- Where
- 6 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- FX Shoulder Solutions
Arthroplasty, Replacement, Shoulder
S-33 SMR Shoulder HP Reverse Glenosphere
Study Design: Single arm, retrospective and prospective, single center, post-market clinical study Purpose:To demonstrate the safety and effectiveness of the SMR Reverse HP Shoulder System device for primary, fracture or revision…
- Trial name
- NCT05339815
- Testing
- SMR shoulder arthroplasty
- Where
- United Kingdom
- Volunteers
- 205 people
- Sponsor
- Limacorporate S.p.a
Rotator Cuff Tears, Rotator Cuff Tear Arthropathy
From Rotator Cuff Repair to Reverse Shoulder Arthroplasty - Clinical and Radiological Results
In the planned study the investigators will invite 733 participants 10 years after arthroscopic rotator cuff repair to a follow up examination. Shoulder pain is a common problem in the Norwegian population.
- Conditions
- Rotator Cuff Tears, Rotator Cuff Tear Arthropathy, Rotator Cuff Injuries
- Trial name
- NCT06644729
- Testing
- Arthroscopic Rotator Cuff Repair
- Where
- Norway
- Volunteers
- 733 people
- Sponsor
- Lovisenberg Diakonale Hospital
Total Shoulder Arthoplasty
TSA Versus RSA in Patients >75
Total shoulder arthroplasty (TSA) has proven to be a predictable and successful operation for the treatment of symptomatic glenohumeral osteoarthritis (GHOA) with an intact rotator cuff.
- Trial name
- NCT04827277
- Testing
- Reverse Total Shoulder Replacement, Anatomic Total Shoulder Replacement
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Analgesia
A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. Master Protocol HTX-011-401.
This is a Phase 4, randomized, blinded, active-controlled, multicohort study to evaluate HTX-011 compared with bupivacaine HCl in subjects undergoing different surgical procedures.
- Trial name
- NCT05109312
- Testing
- Bupivacaine Hydrochloride, HTX-011, Luer lock applicator
- Where
- 7 sites in United States
- Volunteers
- 90 people
- Sponsor
- Heron Therapeutics
Shoulder Arthropathy Associated With Other Conditions
Reverse Shoulder Replacement: Formal vs. Home Physiotherapy
The purpose of this study is to compare range of motion between a structured home exercise program to supervised physiotherapy post-operatively after Reverse Total Shoulder Replacement is performed for rotator cuff tear…
- Trial name
- NCT03430167
- Testing
- home therapy, formal therapy
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Washington University School of Medicine
Shoulder Pain, Opioid Use
Multimodal Analgesia in Shoulder Arthroplasty
Opioid medications are associated with many side effects and the risk of abuse or overdose. Orthopaedic surgeons are currently investigating ways to control pain after surgery while limiting the amount of opioid medications…
- Trial name
- NCT03586934
- Testing
- Acetaminophen, Celecoxib 200mg, Celecoxib 400 mg
- Where
- United States
- Sponsor
- Rush University Medical Center
Shoulder Arthritis, Shoulder Arthropathy Associated With Other Conditions
Closure After Total Shoulder Arthroplasty: Prineo vs Dermabond
The objective is to compare two types of wound closure after total shoulder arthroplasty to determine which closure is faster, and subsequently if there are different outcomes between the two types of closures.
- Trial name
- NCT03899753
- Testing
- 2-Octyl Cyanoacrylate and Mesh, 2-Octyl Cyanoacrylate
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Periprosthetic Joint Infection
A Diagnostic Test Accuracy Study Comparing Biopsy to Aspiration in Shoulder and Elbow Arthroplasty Revision Surgery (BASE Study)
The aim of this study is to compare the diagnostic accuracy of percutaneous aspiration against open biopsy, using microbiological and histological methods, for the detection of shoulder and elbow periprosthetic joint infection…
- Trial name
- NCT06268795
- Where
- United Kingdom
- Volunteers
- 244 people
- Sponsor
- Wrightington, Wigan and Leigh NHS Foundation Trust
Caffeine, Pain, Joint
Pain Management After Shoulder Arthroplasty
Pain control is a critical after many surgical procedures. It is well known that orthopaedic surgeries are among the most painful procedures, with total joint arthroplasty being a clear example of this situation.
- Trial name
- NCT04872270
- Testing
- Total Shoulder Arthroplasty, Caffeine Pill, Percocet 10Mg-325Mg Tablet
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Shoulder Osteoarthritis
Optimizing Recovery After Reverse Shoulder Arthroplasty With a Personalized Mobile Health Application
Background: Mobile health (mHealth) - the use of medical applications in healthcare settings - include tools that can support self-management after surgery and thereby contribute to early postoperative recovery.
- Trial name
- TRAPP (NCT06520085)
- Testing
- interactive mHealth application for patients undergoing RSA
- Where
- 2 sites in Netherlands
- Volunteers
- 170 people
- Sponsor
- VieCuri Medical Centre
Osteoarthritis
Electromyography Evaluation of Subscapularis Function After Total Shoulder Arthroplasty
The primary objective is to document function of the structurally intact subscapularis after total shoulder arthroplasty by using electromyography. Structural integrity of the subscapularis will be confirmed using ultrasound.
- Trial name
- NCT00779974
- Testing
- Evaluation
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Milton S. Hershey Medical Center
Arthroplasty, Replacement, Shoulder
Testosterone Levels and Cutibacterium
Phase 1: In 51 patients undergoing shoulder arthroplasties, total serum testosterone, free testosterone and sex hormone binding globulin levels obtained in the clinic before surgery were correlated with the levels of…
- Trial name
- NCT05030220
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Washington
Shoulder Arthroplasty
A Post-Market Clinical Evaluation of the ReUnion Reverse Shoulder Arthroplasty (RSA) System
This investigation is a prospective, multicenter clinical investigation. It is anticipated that a total of eighty (80) subjects will be enrolled at approximately 4-7 sites.
- Trial name
- NCT03880955
- Testing
- ReUnion RSA System
- Where
- 3 sites in United States
- Volunteers
- 102 people
- Sponsor
- Stryker Trauma and Extremities
Pain, Postoperative
Pain Management After Shoulder Prosthesis: A Clinical Trial of Nerve Block and Local Infiltration
The purpose of this study is to determine the efficacy of local infiltration analgesia as compared to 48-hour interscalene block in treating pain after shoulder arthroplasty.
- Trial name
- NCT01362075
- Testing
- Local infiltration analgesia, Interscalene catheter
- Where
- 2 sites in Denmark
- Volunteers
- 74 people
- Sponsor
- Horsens Hospital
Osteoarthritis, Arthropathy
Liposomal Bupivacaine for Pain Control After Total Shoulder Arthroplasty
This study will compare interscalene nerve block versus liposomal bupivacaine (Exparel) for pain control after total shoulder replacements.
- Conditions
- Osteoarthritis, Arthropathy, Shoulder Pain, Closed Fracture Proximal Humerus, Four Part
- Trial name
- NCT02762071
- Testing
- Liposomal bupivacaine, Interscalene Nerve Block
- Where
- 2 sites in United States
- Volunteers
- 108 people
- Sponsor
- Johns Hopkins University
Total Shoulder Arthroplasty, Shoulder Osteoarthritis
Comparison of Analgesic Efficacy Between of Interscalene Block With Liposomal Bupivacaine With Bupivacaine and Dexamethasone
Pain management after shoulder surgeries poses a unique challenge to the surgeon as well as the anesthesiologist. Regional anesthesia in the form of interscalene approach to the brachial plexus as an adjunct to general anesthesia…
- Trial name
- NCT03969875
- Testing
- Interscalene catheter, Liposomal bupivacaine, Dexamethasone
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Shoulder Joint Disease, Complications; Arthroplasty
Tranexamic Acid in Reverse Total Shoulder Arthroplasty
To the Investigators' knowledge, TXA has not been studied in the setting of reverse total shoulder arthroplasty. We propose a double-blinded, randomized, controlled trial comparing perioperative administration of TXA to placebo…
- Conditions
- Shoulder Joint Disease, Complications; Arthroplasty, Intraoperative Complications, Blood Loss, Surgical
- Trial name
- TXA (NCT02043132)
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Corewell Health East
Propionibacterium Acnes
Propionibacterium Acnes in Shoulder Arthroplasty
The investigator's plan to determine whether pre-operative skin preparation with hydrogen peroxide alters rates of P acnes culture positivity.
- Trial name
- NCT03057821
- Testing
- 3% hydrogen peroxide
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Utah
Arthroplasty, Replacement
INHANCE Stemless Reverse Shoulder IDE
2:1 Randomized, Controlled, Multi-Center, Prospective, Pre-Market Study of the INHANCE Stemless Reverse Cementless Total Shoulder.
- Conditions
- Arthroplasty, Replacement, Shoulder
- Trial name
- NCT06323980
- Testing
- Reverse Total Shoulder
- Where
- 15 sites in United States
- Volunteers
- 168 people
- Sponsor
- DePuy Orthopaedics