Clinical trials: Arthroscopy
Knee Injuries
Trial Comparing BST-CarGel and Microfracture in Repair of Articular Cartilage Lesions in the Knee
This study will investigate whether the treatment of damaged cartilage in the knee with BST-CarGel will increase the amount and quality of cartilage repair tissue when compared with microfracture alone.
- Trial name
- NCT00314236
- Testing
- BST-CarGel with Microfracture, Microfracture without BST-CarGel
- Where
- 18 sites in Canada, South Korea and 1 more
- Volunteers
- 80 people
- Sponsor
- Piramal Healthcare Canada Ltd
Hip Arthroscopy, Nerve Block
Lumbar Plexus Block vs Fascia Iliaca Block After Hip Arthroscopy
The purpose of this study is to compare lumbar plexus block to fascia iliac block done in adult patients who have undergone hip arthroscopy surgery.
- Trial name
- NCT02882633
- Testing
- 30ml bolus of bupivacaine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
Hip Injuries
Opiate Prescribing Guidelines Following Hip Arthroscopy
The purpose of the study is to determine if opiates are required to achieve appropriate analgesia after hip arthroscopy in outpatient surgery.
- Trial name
- NCT04169113
- Testing
- Group 1 - Opiate Tablets post Hip Arthroscopy, Group 2 - Opiate Tablets post Hip Arthroscopy
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Northwestern University
Shoulder Arthroscopy, Pain
Intravenous Dexamethasone on Supraclavicular Brachial Plexus Block for Shoulder Arthroscopy
Previous studies have confirmed that IV dexamethasone prolongs brachial plexus blocks. However, these studies only used fixed doses of IV dexamethasone at relatively high doses, which could potentially lead to increased glucose…
- Trial name
- SCB & IV Dex (NCT02688530)
- Testing
- IV Saline, IV Dexamethasone 4mg, IV Dexamethasone 6mg
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Pain, Shoulder Arthroscopy
Interscalene Block With Low-dose IV vs. Perineural Dexamethasone for Shoulder Arthroscopy
Many patients undergoing ambulatory shoulder arthroscopy experience moderate to severe pain after surgery. Finding ways to minimize postoperative pain are ideal.
- Trial name
- Dex ISB (NCT02506660)
- Testing
- Bupivacaine, Perineural dexamethasone, Intravenous dexamethasone
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Hospital for Special Surgery, New York
Rotator Cuff Syndrome
A Pivotal Study to Assess the InSpace™ Device for Treatment of Full Thickness Massive Rotator Cuff Tears
A pivotal study to assess the safety and effectiveness of the InSpace™ device implantation in comparison to surgical partial repair of full thickness Massive Rotator Cuff Tear (MRCT).
- Trial name
- NCT02493660
- Testing
- InSpace sub-acromial tissue spacer system, Partial repair of rotator cuff
- Where
- 21 sites in United States, Canada
- Volunteers
- 184 people
- Sponsor
- OrthoSpace Ltd.
Anterior Cruciate Ligament Tear, Knee Meniscus Tear
Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength
The purpose of this study is to compare the effects of a femoral nerve block vs. an adductor canal block on pain and quadriceps muscle strength for knee arthroscopy surgery.
- Trial name
- NCT05190120
- Testing
- Femoral Nerve Block, Adductor Canal Nerve Block, preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of California, San Francisco
Hip Labral Tears
Evaluation of Perioperative Celecoxib for Hip Arthroscopy
Celecoxib is commonly used for perioperative pain control for certain orthopaedic procedures. It has been shown to be successful in assisting in pain control for knee arthroscopy.
- Trial name
- Celecoxib (NCT02779166)
- Testing
- Celecoxib
- Volunteers
- 98 people
- Sponsor
- Northwestern University
Rotator Cuff Tears, Hemorrhage, Surgical
Effect of Intravenous Tranexamic Acid on Visual Clarity During Shoulder Arthroscopy in the Beach Chair Position
Shoulder arthroscopy offers numerous advantages and has led to a continuous increase in procedural complexity. Adequate intraoperative visual clarity is essential for successful performance of the procedure and is primarily…
- Conditions
- Rotator Cuff Tears, Hemorrhage, Surgical, Shoulder Injuries
- Trial name
- NCT05397652
- Testing
- Tranexamic Acid Injectable Product
- Where
- Croatia
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Nikola Matejcic
Knee Injuries, ACL Injury
Opiates Prescribing for Knee Arthroscopies and ACL Reconstruction
The purpose of the study is to determine if opiates are required to achieve adequate analgesia after knee arthroscopy and ACL reconstruction in outpatient surgery.
- Trial name
- NCT03876743
- Testing
- Group 1-Knee Arthroscopy, Group 2-Knee Arthroscopy, Group 1-ACL reconstruction
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Northwestern University
Degenerative Meniscal Tear
Surgical or Exercise Therapy on Patients With Degenerative Meniscus Tears
This study is conducted as a collaboration between NAR, Orthopedic Department, Oslo University Hospital,Ullevaal, Hjelp24Nimi Oslo, Martina Hansens Hospital Norway, and University of Southern Denmark, Odense, Denmark.
- Trial name
- OMEX (NCT01002794)
- Testing
- Arthroscopic partial menisectomy, Supervised neuromuscular and strength training
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
Knee Injury
Decadron as Adjuvant in Femoral Nerve Blocks in Knee Arthroscopy
If preservative-free dexamethasone 0.1 mg/kg (max dose 4 mg) is added to ropivacaine 0.5% 2 mg/kg (max dose 100 mg), then post-PACU opioid consumption will be reduced by 33%.
- Trial name
- NCT01971645
- Testing
- Dexamethasone, Ropivacaine
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Nationwide Children's Hospital
Meniscus Tear, Retention; Meniscus
Circumferential Compression STITCH Repairs of Complex and Horizontal Cleavage Meniscal Tears
The purpose of this study is to understand the benefits and safety of the NOVOSTITCH PRO Meniscal Repair (NOVOSTITCH PRO) system. The meniscus is a tissue in the knee joint.
- Trial name
- NOVOSTITCH PRO (NCT04361487)
- Testing
- NOVOSTITCH™ PRO Meniscal Repair System
- Where
- 6 sites in United States
- Volunteers
- 33 people
- Sponsor
- Smith & Nephew, Inc.
Pain
Comparison of a Pain Pump Versus Injectable Medication for Analgesia in Knee Arthroscopy
Hypothesis: Ropivacaine, morphine and ketorolac injected after knee arthroscopy is as effective as this solution plus ropivacaine administered intra-articularly for twenty-four hours.
- Trial name
- NCT01242644
- Testing
- pain pump containing ropivacaine, saline pain pump with injectable medication, ropivacaine, ketorolac , morphine sulfate
- Volunteers
- 48 people
- Sponsor
- University of South Alabama
Shoulder Arthroscopy
Subacromial Injection of Epinephrine Improves Visualization in Shoulder Arthroscopy
The purpose of this study is to evaluate surgeon-rated visual clarity and the need for increased irrigation pump pressure during arthroscopic shoulder surgery and to evaluate mean arterial pressure, operative time, and any…
- Trial name
- NCT05244525
- Testing
- Bupivacaine with Epinephrine, Bupivacaine alone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The University of Texas Health Science Center, Houston
Internal Derangement of Knee
Infrapatellar Nerve Block for Post-operative Knee Arthroscopy Pain Control
The purpose of this study is to determine whether infrapatellar branch of the saphenous nerve blocks are effective in decreasing analgesic use, promoting earlier mobility, and improving long term outcome scores after knee…
- Trial name
- NCT01279447
- Testing
- 0.25% Bupivacaine, Normal Saline
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pain, Postoperative
The Use of Cannabidiol (CBD) in Pain Reduction and Opioid Use After Shoulder Arthroscopy
This study is designed to evaluate the effects of administering CBD to control post-operative pain in patients undergoing shoulder arthroscopy.
- Trial name
- NCT04672252
- Testing
- CBD Oral Disintegrating Tablet (ODT)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Meniscal Tear, Meniscus Tear
Study of Suture Repair of Torn Meniscus in the Knee
Horizontal meniscus tears meeting specified criteria will be repaired by any commonly used suture technique. Subjects will be followed for 2 years to evaluate the effectiveness of the repair, by assessing the re-operation rate…
- Trial name
- STITCH (NCT02237001)
- Testing
- Suture-based meniscal repair
- Where
- 8 sites in United States
- Volunteers
- 30 people
- Sponsor
- Smith & Nephew, Inc.
Arthroscopic Knee Surgery
Study to Find Optimal Dose of Local Spinal Anesthetic (Mepivacaine) Combined With Narcotic (Fentanyl) For Knee Surgery
Prolonged motor block and delayed ability to walk are limitations of spinal anesthesia in ambulatory (same-day) surgery. This can be improved by lowering the dose of local anesthetic (a medication that, when injected around…
- Trial name
- NCT01701102
- Testing
- Mepivacaine (24 mg) plus fentanyl, Mepivacaine (27 mg) plus fentanyl, Mepivacaine (30 mg) plus fentanyl
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Shoulder Arthroscopy, Interscalene Block
Effect of Local Anesthetic Dose on Interscalene Block
The purpose of this study is to determine if a decrease in the standard volume of local anesthetic used to numb your shoulder area before shoulder arthroscopy will provide adequate anesthesia for the procedure and decrease the…
- Trial name
- Low Dose ISB (NCT01701115)
- Testing
- Low Dose (20 ml) Local Anesthetic Volume for Interscalene Block, Control Dose (40 mL) Local Anesthetic Volume for Interscalene Block, Low Dose (20 mL) Local Anesthetic (Mepivacaine:Bupivacaine)
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York