Clinical trials: Arthrosis; Spine
Shoulder Pain, Shoulder Impingement Syndrome
Thoracic Spine and Shoulder Kinematics and Muscle Activation in Rock Climbers With Shoulder Pain
Background and Purpose: Rock climbing has been a popular sport in recent years. Rock climbing includes various open-chain and closed-chain arm movements.
- Trial name
- NCT05950360
- Testing
- Electromagnetic tracking system, surface electromyography
- Where
- Taiwan
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Osteoarthritis, Hip, Osteoarthritis, Knee
Non-invasive Evaluation of Upper and Lower Body Function With Showmotion
It is very important to understand joint and body kinematics and muscles activity in clinical settings, which is relevant to identify issues related to the spine, the upper and lower limbs due to injury.
- Conditions
- Osteoarthritis, Hip, Osteoarthritis, Knee, Osteoarthritis, Spine
- Trial name
- NCT04137835
- Testing
- Showmotion
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Lumbar Osteoarthritis, Spondylosis
Post-op Acetaminophen vs NSAID Use on Lumbar Spinal Fusion Outcomes
Patients undergoing spine surgery often have considerable pain post-operatively and frequently require opioid medication (Percocet, Norco, oxycodone, morphine, etc.) to control their pain postoperatively.
- Conditions
- Lumbar Osteoarthritis, Spondylosis, Lumbar Disc Disease, Spinal Stenosis
- Trial name
- NCT02700451
- Testing
- Ketorolac, Acetaminophen
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Hospital for Special Surgery, New York
Temporomandibular Disorder
Cervical Spine Thrust Joint Manipulation for Temporomandibular Disorder
Background: Temporomandibular disorder (TMD) is a common and costly problem that often leads to chronic pain or dysfunction. There is moderate evidence to support physical therapy (PT) interventions for individuals with TMD, yet…
- Trial name
- NCT03300297
- Testing
- Cervical Spine Thrust Joint Manipulation, Home Program, Suboccipital Release
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Bradley University
Radius; Deformity, Hip Osteoarthritis
Clinical Evaluation and Cost-effectiveness Analysis of 3D Digital Surgery in Traumatology
Digital surgery, in combination with patient specific instrumentation (PSI) is being used more and more in traumatology due to its proven benefits and applications.
- Conditions
- Radius; Deformity, Hip Osteoarthritis, Hip Arthritis, Hip Arthropathy
- Trial name
- NCT06603831
- Testing
- patients treated using 3D technology and Patient-Specific Instrumentation, Patients treated with conventional surgery, without using 3D technology
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Corporacion Parc Tauli
Temporomandibular Disorder
Effectiveness of Different Physiotherapy Practices in Temporomandibular Disorders
The aim of the study is to examine the effect of high voltage electrical stimulation on pain, temporomandibular joint mobility, cervical mobility, head position, tender points and joint sounds in individuals with…
- Trial name
- NCT04708938
- Testing
- High voltage electrical stimulation+exercise therapy, Exercise therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Gazi University
Lower Back Pain Chronic, Facet Joint Arthrosis
Evaluation of Pain Level Reduction After Low-dose Radiation in Symptomatic Facet Joint Arthritis
The goal of this clinical trial is to compare low-dose radiation therapy (LDRT) with intra-articular steroid injections in participants suffering from chronic lower back pain as cause of facet joint arthritis (FJA).
- Conditions
- Lower Back Pain Chronic, Facet Joint Arthrosis, Osteoarthritis, Spine
- Trial name
- LORAFA (NCT05852808)
- Testing
- Intra-articular steroid injections, Low-dose radiation therapy
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- Silvia Gomez Ordonez
Platelet-Rich Plasma
Platelet-Rich Plasma (PRP) for Treatment of Symptomatic Lumbar Facet Syndrome of the Spine
The purpose of this study is to investigate the feasibility of standardized autologous platelet rich plasma injections into osteoarthritic lumbar facet joints to treat back pain and improve patient function.
- Trial name
- NCT04522674
- Testing
- Autologous platelet rich plasma
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Colorado, Denver
Low Back Pain, Leg Pain
Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis
The purpose of this multi-center, randomized, clinical study is to establish the safety and effectiveness of the TOPS™ System, used following decompression, in the treatment of lower back and leg pain with, or without spinal…
- Conditions
- Low Back Pain, Leg Pain, Spondylolisthesis, Lumbar Spinal Stenosis
- Trial name
- NCT00405691
- Testing
- "TOPS System" - Total Posterior Arthroplasty Implant
- Where
- 16 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Impliant, Ltd.
Intervertebral Disc Degeneration, Osteoarthritis, Spine
Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers
A study of the skeletal structure and how the structure changes over time. The aim of the study is to evaluate the skeleton in 10 year increments to determine an understanding of the normal skeleton as a person ages.
- Trial name
- NCT03076658
- Testing
- EOS imaging
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Lumbar Spondylolisthesis, Arthrosis; Spine
Analysis of the Clinical Efficacy of Intravenous Application of Hemostatic Drugs in Improving the Clarity of Vision Under Endoscope, Perioperative Bleeding Volume and Anti-inflammatory Effect of Spinal Endoscopic Lumbar Fusion
To study the clinical efficacy of carosodiumsulfonate and desmopressin in improving the clarity of vision under endoscope, perioperative bleeding volume and anti-inflammatory effect in endoscopic lumbar fusion
- Trial name
- NCT06255366
- Testing
- Caroxime sodium sulfonate, Desmopressin, 0.9% Sodium Chloride Injection
- Volunteers
- 126 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Degenerative Disc Disease, Back Pain Lower Back Chronic
The SPINUS II Study: Spinal Fusion for Multilevel SPECT/CT Positive Lumbar Degeneration
The aim of the present study is to find out whether fusion of multilevel SPECT/CT positive lumbar degeneration leads to a significant improvement of pain and disability.
- Conditions
- Degenerative Disc Disease, Back Pain Lower Back Chronic, Facet Joint Arthropathy, Facet Syndrome of Lumbar Spine
- Trial name
- NCT04893720
- Testing
- Lumbar fusion
- Where
- 2 sites in Czechia
- Volunteers
- 30 people
- Sponsor
- Military University Hospital, Prague
Temporomandibular Joint Dysfunction Syndrome
Manual Therapy and Exercises Applied to Cervical Spine in Patients With Temporomandibular Disorders
The objective of this study was to investigate the effect of a manual therapy and exercise program, focused on the rehabilitation of cervical function, on clinical signs and mandibular function in subjects with TMD.
- Trial name
- NCT01954511
- Testing
- Manual therapy, Pressure biofeedback device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Osteoarthritis of Facet Joint of Lumbar Spine
Safety of Adipose-derived Regenerative Cells Injection for Treatment of Osteoarthritis of the Facet Joint
This is a prospective, randomized, active controlled, single site safety and efficacy study in subjects suffering from chronic lumber back pain due to facet joint osteoarthritis comparing a single ADRC injection generated with…
- Trial name
- NCT03513731
- Testing
- Adipose-derived stem cell injection, Corticosteroid injection
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- InGeneron, Inc.
Dysphagia, GERD
Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgery
The researchers wish to investigate whether proton pump inhibitors, administered prior to or after surgery, can reduce the incidence and/or severity of difficulty swallowing foods and/or liquids,following anterior cervical…
- Conditions
- Dysphagia, GERD, Degenerative Joint Disease
- Trial name
- NCT03488147
- Testing
- Esomeprazole
- Where
- 2 sites in United States
- Sponsor
- Icahn School of Medicine at Mount Sinai
Total Hip Arthroplasty
In Patients With Hip Dysplasia, Mid-Term Lower Extremities and Spine After Hip Arthroplasty Natural Course
Patients with developmental hip dysplasia often present to the outpatient clinic in adulthood with hip pain due to progressive hip osteoarthritis.
- Trial name
- NCT06176612
- Testing
- total hip arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Bezmialem Vakif University
Osteoarthritis, Pain
Norspan® Patches Versus Tramadol in Subjects With Chronic, Moderate to Severe Osteoarthritis Pain in the Hip Knee and/or Lumbar Spine
The primary objective of this equivalence study is to evaluate the efficacy of Norspan® patches versus Tramadol in subjects with chronic, moderate to severe osteoarthritis pain of the hip, knee and/or lumbar spine.
- Trial name
- NCT00426647
- Testing
- Buprenorphine, Tramadol
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Norpharma A/S
Intervertebral Disc Degeneration
Safety and Performance of the SPINEVISION Hexanium ACIF in the Treatment of Cervical Spine Degenerative Disc Disease
The goal of this observational study is to confirm the safety and efficacy of the Hexanium ACIF system in the treatment of skeletally mature patients suffering from degenerative disc disease (disease that occurs when the spinal…
- Trial name
- NCT06155409
- Testing
- Anterior cervical interbody fusion
- Where
- 6 sites in France
- Volunteers
- 148 people
- Sponsor
- SPINEVISION SAS
Arthrodesis, Post-operative Care
Effect of Osteopathy Medicine on Post-surgical Management of Lumbosacral Arthrodesis
Introduction : Low back pain represents a major public health issue. In some cases, surgery may be necessary, but it is not without consequences.
- Conditions
- Arthrodesis, Post-operative Care, Manual Therapy, Lumbar Spine Surgery
- Trial name
- NCT06669858
- Testing
- manual therapy
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Centre Européen d'Enseignement Supérieur de l'Ostéopathie de Lyon
Degenerative Arthropathy of Lumbar Spinal Facet Joint
Prognostic Factors in Zygapophyseal Osteoarthritis Infiltration: a Prospective Cohort Study
Magnet Resonance Image findings of facet osteoarthritis and patient characteristics are prognostic factors for improving or worsening the clinical outcome after treatment with facet infiltration.
- Trial name
- NCT03304730
- Where
- Brazil
- Volunteers
- 147 people
- Sponsor
- Hospital Israelita Albert Einstein