Clinical trials: Articular Disease
Knee Osteoarthritis
The Comparison of Knee Osteoarthritis Treatment With Bone Marrow Aspirate Concentrate , Leukocyte Rich Platelet Rich Plasma and Hyaluronic Acid
The aim of this study is to compare therapeutic and clinical effects of intra-articular injection of Bone Marrow Aspirate Concentrate (BMAC), inta-articular injection of Leukocyte Rich Platelet Rich plasma (LR-PRP) and 3 weekly…
- Trial name
- NCT03825133
- Testing
- Bone Marrow Aspirate Concentrate, Leukocyte Rich Platelet Rich Plasma, Hyaluronic Acid
- Where
- Serbia
- Volunteers
- 180 people
- Sponsor
- Clinical Center of Vojvodina
Pain Dysfunction, Sleep Disturbance
Cognitive Behavioral Therapy for Arthritis Pain and Insomnia in Older Adults
This study compares the efficacy of three group interventions for people with co-morbid osteoarthritis (OA) and insomnia to help them manage their OA symptoms.
- Conditions
- Pain Dysfunction, Sleep Disturbance, Osteoarthritis
- Trial name
- Lifestyles (NCT01142349)
- Testing
- Lifestyles A, Lifestyles B, Lifestyles C
- Where
- 2 sites in United States
- Volunteers
- 367 people
- Sponsor
- University of Washington
Arthritis
ThermRheum Version 1
Childhood arthritis is a diagnosis made by clinicians based upon their clinical examination, during which patients are assessed for signs of swelling, warmth and restricted movement of the joints using the sensation of touch.
- Trial name
- ThermRheum (NCT04228458)
- Testing
- Thermal Imaging
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Osteoarthritis (OA) of the Knee, Osteoarthritis Knee Pain
First in Human Study of SakuraBead for Genicular Artery Embolization to Treat Pain Secondary to Knee Osteoarthritis
A prospective, single-centre, single-arm, unmasked, First in Human study that aims to evaluate the safety and efficacy of SakuraBead resorbable microspheres in adult patients suffering from pain secondary to knee osteoarthritis.
- Conditions
- Osteoarthritis (OA) of the Knee, Osteoarthritis Knee Pain, Joint Diseases, Musculoskeletal Diseases
- Trial name
- NCT06718478
- Testing
- SakuraBead Resorbable Microspheres
- Where
- Uzbekistan
- Volunteers
- 15 people
- Sponsor
- CrannMed
Diabetes Mellitus, Insulin Hypoglycemia
Information and Communication Technology Based Centralized Clinical Trial Monitoring System for Insulin Dose Adjustment
This is a 24-week, open-label, randomized, multi-center trial conducted in three tertiary hospitals. There are three follow-up measures; at baseline, post-intervention at Week 12, and Week 24.
- Conditions
- Diabetes Mellitus, Insulin Hypoglycemia, Insulin-dependent Diabetes Mellitus
- Trial name
- ICT (NCT03112343)
- Testing
- Algorithm-based feedback messages, Personal Health Record
- Where
- South Korea
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Temporomandibular Joint Disorders
Correlation Between Craniovertebral Angle and Temporomandibular Disorders
The purpose of study was investigate the correlation between craniovertebral angle and Temporomandibular disorders.
- Trial name
- NCT07522749
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Knee Osteoarthritis
Calisthenic and Neuromuscular Training in Patients With Knee OA.
The aim of the study is to compare effects of calisthenics and neuromuscular training in patients with knee osteoarthritis.
- Trial name
- NCT05173649
- Testing
- Calisthenic Training, Neuromuscular Training
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Osteoarthritis of the Knee
A Multiple Injection Study Evaluating Safety and Efficacy of Ampion in Osteoarthritis
This study will evaluate the efficacy of three intra-articular injections, given 2 weeks apart, of Ampion™ in Adults with pain due to osteoarthritis of the knee.
- Trial name
- NCT02242435
- Testing
- 4 mL injection of Ampion
- Where
- United States
- Volunteers
- 342 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Rheumatoid Arthritis
Oral CF101 and Methotrexate Treatment in Rheumatoid Arthritis Patients
This trial will test the hypothesis that the addition of CF101, a novel anti-inflammatory agent, will improve the clinical condition of patients with rheumatoid arthritis who still have active joint inflammation despite taking…
- Trial name
- NCT00280917
- Testing
- CF101
- Where
- 35 sites in United States, Bulgaria and 5 more
- Volunteers
- 254 people
- Sponsor
- Can-Fite BioPharma
Hip Pain Chronic, Femoro Acetabular Impingement
Education and Exercise for Patients With Longstanding Hip and Groin Pain
Longstanding hip and groin pain (LHGP) is a common and debilitating problem in young to middle aged individuals. These patients often get referred to orthopedic departments.
- Conditions
- Hip Pain Chronic, Femoro Acetabular Impingement, Groin Injury
- Trial name
- HIPSTER (NCT05853640)
- Testing
- Usual care, HIPSTER
- Where
- Sweden
- Volunteers
- 122 people
- Sponsor
- Lund University
Osteoarthritis of the Knee
Teriparatide for Improved Knee Prosthesis Fixation
The investigators will study how well knee joint prostheses become fixed to the bone when patients get teriparatide, compared to placebo. Measurements will use high resolution 3D radiography (radiostereometry, RSA).
- Trial name
- NCT01063504
- Testing
- teriparatide
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- University Hospital, Linkoeping
Effusion Joint
Ultrasound Guided Versus Landmark Guided Small & Medium Joint Arthrocentesis
Arthrocentesis is the removal of synovial fluid for analysis of pathologic processes. Small \& medium joint arthrocentesis will be defined as the following joints: elbow, wrist, finger, ankle and toe.
- Trial name
- NCT03327584
- Testing
- Arthrocentesis
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Temple University
Knee Osteoarthritis
Total Knee Arthroplasty With Vitamin E Polyethylene
The aim of this observational study is to investigate if there is any difference in survival rate, clinical and radiological results after total knee replacement with vitamin E-blended polyethylene in comparison to conventional…
- Trial name
- NCT05810285
- Testing
- GKS Prime Flex Mobile knee
- Where
- Italy
- Volunteers
- 186 people
- Sponsor
- Permedica spa
Hemophilia A and B
Comparison of 30-Second Sit-to-Stand Test Performance Between Individuals With Hemophilia and Healthy Peers
Hemophilia is an inherited bleeding disorder characterized by recurrent musculoskeletal bleeding, particularly into joints, leading to impaired physical function and reduced functional performance.
- Trial name
- NCT07736976
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Knee Dislocation
Compass Hinge Stabilization of Knee Dislocations: A Randomized Trial
The purpose of this project is to evaluate the effect of the Compass™ Universal Hinge external fixator on the outcome of patients following acute dislocation of the knee
- Trial name
- CKH (NCT00582517)
- Testing
- Compass Universal Hinge External Fixator, Non-invasive External Knee Brace
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Osteoarthritis
A Randomized Clinical Study Comparing a Fully-Coated Cementless Stem Versus a Cemented Stem for Total Hip Replacements
The purpose of this study is to answer the question as to whether or not a fully coated cementless stem is equal to or better than a cemented stem in patients over 72 years with good bone quality.
- Trial name
- NCT00689689
- Testing
- Fully coated Prodigy stem, Cemented Endurance Stem
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Nova Scotia Health Authority
Ankylosing Spondylitis (AS)
BI 655066 (Risankizumab) Proof of Concept Dose Finding Study in Ankylosing Spondylitis (AS)
The overall purpose of the trial is to assess the clinical efficacy of three different subcutaneous doses of BI 655066 (risankizumab) in adult patients with AS, in order to provide clinical proof of concept and to select dose (s)…
- Trial name
- NCT02047110
- Testing
- risankizumab
- Volunteers
- 159 people
- Sponsor
- AbbVie
Pain, Chronic Postsurgical, Knee Osteoarthritis
Central Sensitization in Total Knee Arthroplasty Patients with Persistent Pain
Persistent post-surgical pain is a significant adverse effect after total knee arthroplasty, present in around 20% of the patients. Central sensitization may contribute to developing and maintaining pain.
- Conditions
- Pain, Chronic Postsurgical, Knee Osteoarthritis, Sensitization, Central
- Trial name
- NCT05575310
- Testing
- Total Knee Arthroplasty
- Where
- Spain
- Volunteers
- 117 people
- Sponsor
- University of Barcelona
Juvenile Idiopathic Arthritis
Pain in Juvenile Arthritis
Juvenile idiopathic arthritis (JIA) is the most common rheumatologic disease in children. The main symptoms of JIA, which are often the primary focus of treatment, include joint swelling, stiffness, and tenderness.
- Trial name
- NCT07217782
- Testing
- Pressure pain thresholds (measured in kilopascal), Cold pain tolerance (duration in seconds)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Ankylosing Spondylitis
Basic Documentation of Adalimumab (Humira) in Patients With Ankylosing Spondylitis (AS)
The research question explored in this study was whether the effectiveness and safety of adalimumab in participants with ankylosing spondylitis was maintained during long-term therapy in routine clinical practice in Germany.
- Trial name
- NCT01079182
- Volunteers
- 4,681 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
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