Clinical trials: Articular Disease
Rhizarthrosis
Study of Medical Ultrasound for Rhizarthrosis
It was never investigated which preservative non-invasive treatments are superior to treat rhizarthrosis. This randomized study compares the effect of 1. hand therapy vs. 2. therapeutic ultrasound vs. 3.
- Trial name
- NCT04115085
- Testing
- Hand therapy (18 treatments), Therapeutic ultrasound (18 treatments), Combined hand therapy and therapeutic ultrasound (18 treatments)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Waldfriede Hospital
Arthritis, Rheumatoid, Crohn Disease
A Long-term Safety Study of Infliximab (Remicade)
This is a study evaluating the long-term safety of infliximab (Remicade)
- Conditions
- Arthritis, Rheumatoid, Crohn Disease, Psoriasis
- Trial name
- NCT00261976
- Testing
- Infliximab (Remicade)
- Where
- 205 sites in United States, Argentina and 17 more
- Volunteers
- 2,971 people
- Sponsor
- Centocor, Inc.
Shoulder Pain
Effect of Wheelchair Handrail Compensator and Rehabilitation Training for Patients With Hemiplegic Shoulder Pain
The purpose of this study is to determine whether wheelchair handrail compensator plus rehabilitation training could do better than ordinary wheelchair plus rehabilitation training in relieving pain and improving daily life…
- Trial name
- EHSP (NCT02837068)
- Testing
- Wheelchair handrail compensator, Ordinary wheelchair
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Rheumatoid Arthritis
Study of Apremilast to Evaluate the Safety and Effectiveness for Patients With Rheumatoid Arthritis
The purpose of this study is to determine whether Apremilast is safe and effective in the treatment of patients with rheumatoid arthritis, specifically in improving signs and symptoms of rheumatoid arthritis (tender and swollen…
- Trial name
- NCT01285310
- Testing
- Apremilast 30 mg, Apremilast 20 mg
- Where
- 50 sites in United States, Czechia and 2 more
- Volunteers
- 237 people
- Sponsor
- Amgen
Osteoarthritis, Knee
Intra and Inter Reliability of 30 Seconds Chair Stand Test as Self-test for Patients With Knee Osteoarthritis.
Background: It is estimated that 14% of the Swedish population have knee osteoarthritis. Common osteoarthritis symptoms are pain, stiffness and impaired physical function.
- Trial name
- NCT03855813
- Testing
- Intra rater reliability, Inter rater reliability
- Where
- 3 sites in Sweden
- Volunteers
- 129 people
- Sponsor
- Vastra Gotaland Region
Temporomandibular Joint Dysfunction Syndrome, Autonomic Nervous System Imbalance
The Effect of Vagus Nerve Stimulation on Temporomandibular Joint Dysfunction
Temporomandibular joint dysfunction (TMD) is a broad clinical picture involving the TMJ and its disc, masticatory musculature, ligament tissue, and autonomic nervous system (ANS).
- Trial name
- NCT05500716
- Testing
- Auricular Non-Invazive Vagus Nerve Stimulation + Traditional Rehabilitation Program for TMD, Traditional Rehabilitation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Alper Percin
Knee Osteoarthritis
Quantitative MRI For Detection and Tracking of Knee Osteoarthritis
The goal of this observational study is to develop whole-joint quantitative MRI techniques that aid in the detection and tracking of osteoarthritis disease progression at 3T and 7T MRI scanners. The research objectives are: 1.
- Trial name
- NCT06063304
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Knee Pain
A Reliability and Validity Study of Urdu Version of Knee Outcome Survey-Activities of Daily Living Scale
The purpose of this study is to translate Knee Outcome Survey-Activities of Daily Living Scale into Urdu language and to check the reliability and validity of the Knee Outcome Survey-Activities of Daily Living Scale in Urdu…
- Trial name
- NCT05221047
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Riphah International University
Knee Osteoarthritis
Effectiveness and Safety of Embosphere Microspheres for Embolization of the Geniculate Artery for the Treatment of Pain With Known Moderate to Severe Knee Osteoarthritis
The purpose of this research study is to evaluate the effectiveness and safety of a permanent embolic (Embosphere Microspheres) for embolization of the geniculate artery for the treatment of moderate to severe knee osteoarthritis.
- Trial name
- NCT05112926
- Testing
- Embosphere Microspheres
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Miami
Rheumatoid Arthritis
A Study of LNK01001 Capsule in Moderately to Severely Active Rheumatoid Arthritis
This study includes two periods. In Period 1, Participants who meet eligibility criteria will be randomized in a 1:1:1 ratio to receive a twice-daily oral LNK01001 Dose A or LNK01001 Dose B or a matching placebo for 12 weeks.
- Trial name
- NCT06099535
- Testing
- LNK01001 Dose A, LNK01001 Dose B
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Lynk Pharmaceuticals Co., Ltd
Rheumatoid Arthritis
A Magnetic Resonance Imaging Study and Arthroscopic Biopsy Substudy in Subjects With Active Rheumatoid Arthritis Receiving VX-509, an Oral JAK3 Inhibitor
The current study is designed to evaluate the safety and efficacy, including MRI imaging, across a range of VX-509 doses in subjects with active rheumatoid arthritis (RA) who have had an inadequate response to disease-modifying…
- Trial name
- NCT01754935
- Testing
- VX-509
- Where
- 30 sites in United States, Denmark and 4 more
- Volunteers
- 43 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Knee Osteoarthritis
Comparison of Mini Squat and Endurance Training in Improving Quality of Life in Knee Osteoarthritis
Interventional type of study in which one group of participants will be given mini squats training and other endurance training to improve the quality of life of knee osteoarthritis patients.
- Trial name
- NCT06056076
- Testing
- Mini Squats Training, Endurance Training
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neuro Counsel Hospital, Pakistan
Obesity, Weight Loss
Impact of the Excess Weight Loss on Mineralization Patterns of the Knee After Bariatric Operations
Evaluation of the subchondral mineralization plate after excess weight loss in patientes undergoing bariatric operation by means of CT-osteoabsorptiometry.
- Conditions
- Obesity, Weight Loss, Knee Osteoarthritis
- Trial name
- CT-OAM (NCT02404090)
- Testing
- CT-osteoarbsorptiometry
- Volunteers
- 50 people
- Sponsor
- Marko Kraljevic
Osteoarthritis
Buprenorphine Transdermal Patch in Subjects With Osteoarthritis Pain Requiring Opioids. Includes a 52-Week Safety Extension.
The original objective of this study was to assess the safety and efficacy of the buprenorphine transdermal system (BTDS) (5, 10, and 20) in comparison to placebo transdermal system in subjects with moderate to severe…
- Trial name
- NCT00315458
- Testing
- Buprenorphine transdermal patch
- Where
- 48 sites in United States
- Volunteers
- 107 people
- Sponsor
- Purdue Pharma LP
Paraplegia, Upper Limb Pain
Adjusting Wheelchair Set-Up to Minimize Shoulder Joint Forces During Propulsion
Individuals who use a manual wheelchair depend upon their upper limbs to provide a means of locomotion during completion of their activities of daily living.
- Trial name
- NCT00785278
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Anemia, Rheumatoid Arthritis
Randomized, Double-blind, Placebo-controlled Study to Assess Fatigue in Patients With ACD Due to RA Receiving PROCRIT
The purpose of this research study is to determine fatigue (tiredness) in subjects with chronic Rheumatoid Arthritis with chronic anemia.
- Trial name
- NCT00236678
- Testing
- Epoetin alfa
- Volunteers
- 29 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Meniscus Tear, Tibial, Osteoarthritis, Knee
Arthroscopic Partial Meniscectomy Versus Exercise Therapy for Meniscal Injuries in Older Patients, a 5 Year Follow up.
Arthroscopic partial meniscectomie (APM) offers little short-term to medium-term benefit above sham surgery or non-surgical management for knee function in most patients with a symptomatic degenerative meniscus tear.
- Trial name
- NCT05068843
- Testing
- arthroscopic partial meniscectomy, Physical therapy
- Volunteers
- 321 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Low Back Pain
Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain
This is a Pilot Study that is an open label, prospective, non-controlled study in which the safety and feasibility of Wharton's Jelly (WJ) allograft will be evaluated in 100 participants suffering with low back pain.
- Trial name
- NCT06361485
- Testing
- Lumbar Injections with 10cc's of Wharton's Jelly Allograft
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- R3 Stem Cell
Frozen Shoulder, Adhesive Capsulitis
Spencer's Technique Versus Mulligan's Technique for Stage II Frozen Shoulder
Stage II frozen shoulder (adhesive capsulitis) is associated with pain, stiffness, restricted shoulder range of motion, and reduced quality of life.
- Trial name
- NCT07844135
- Testing
- Spencer's Muscle Energy Technique With Conventional Physiotherapy, Mulligan's Mobilization With Movement With Conventional Physiotherapy
- Where
- 2 sites in Pakistan
- Volunteers
- 72 people
- Sponsor
- Superior University
Arthritis, Arthralgia
Methotrexate for Immune Related Arthritis or Arthralgias (IMPACT 2.1)
Many people develop joint pain, stiffness and swelling due to their cancer treatment that targets the immune system. The severity of symptoms ranges from mild to debilitating and sometimes requires delaying or stopping cancer…
- Trial name
- NCT06001125
- Testing
- Methotrexate
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- AHS Cancer Control Alberta
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