Clinical trials: Articular Disease
Shoulder Impingement Syndrome
Randomized Clinical Trial of Rehabilitation for Subacromial Impingement Syndrome
The purpose of this randomized double-blind clinical trial is to determine the effectiveness of manual therapy for patients with subacromial impingement syndrome of the shoulder.
- Trial name
- NCT00633451
- Testing
- Manual Therapy and Exercise, Exercise Only
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Proaxis Therapy
Disorder of Shoulder, Other Musculoskeletal Disorder
The Acute Effect of a Mobilization With Movement Technique to Improve Internal Rotation of the Shoulder
For many years researchers have been documented that the shoulder of the throwing athlete acquires a increase in external rotation of the dominant limb compared to the contralateral side.This fact is followed with a loss of the…
- Conditions
- Disorder of Shoulder, Other Musculoskeletal Disorder, Contracture
- Trial name
- NCT01639651
- Testing
- Posterior capsule stretching, Mobilization with movement
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Physical Disability, Joint Function Disorder
Mexican Initiative of Patients With Osteoarthritis and Rheumatoid Arthritis (IMPACTAR)
The purpose of this study is to evaluate quality of life, degree of disability, treatment patterns and economic impact of hand and knee Osteoarthritis and Rheumatoid Arthritis in Mexico.
- Conditions
- Physical Disability, Joint Function Disorder, Axis IV Problems Economic, Compliance Behavior
- Trial name
- IMPACTAR (NCT02124031)
- Volunteers
- 10,241 people
- Sponsor
- Iniciativa Mexicana de Pacientes con Osteoartritis y Artritis Reumatoide
Facet Joint Arthritis, Facet Joints; Degeneration
Reliability and Reproducibility of CT-Based Facet Joint Measurements in Patients With AOSpine Type A2, A3, and A4 Thoracolumbar Fractures
The Reliability Evaluation of Facet joint Assessment by Computed Tomography in thoracolumbar fractures (REFACT) study aims to evaluate how consistently different specialists assess thoracolumbar facet joints on computed…
- Conditions
- Facet Joint Arthritis, Facet Joints; Degeneration, Facet Joint Disease, Intervertebral Disk Degeneration
- Trial name
- REFACT (NCT07670039)
- Testing
- Computed Tomography Image Review
- Where
- Russia
- Volunteers
- 12 people
- Sponsor
- Sklifosovsky Institute of Emergency Care
Rheumatoid Arthritis
Study Evaluating the Analgesic Efficacy and Safety of ADL5859 in Participants With Rheumatoid Arthritis
The purpose of this study is to evaluate the effectiveness of ADL5859 in relieving pain associated with rheumatoid arthritis (RA) compared with placebo and naproxen (similar to Aleve®).
- Trial name
- NCT00626275
- Testing
- ADL5859, Naproxen
- Where
- 8 sites in United States
- Volunteers
- 46 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Rheumatoid Arthritis (RA)
Validity And Reliability Of The Four Square Step Test In Individuals With Rheumatoid Arthritis
This cross-sectional observational study aims to evaluate the validity and reliability of the Four Square Step Test (FSST) in individuals with rheumatoid arthritis.
- Trial name
- NCT07264101
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Inonu University
Osteoarthritis
Evaluation of DVD and Internet Decision Aids for Hip and Knee Osteoarthritis: Focus on Health Literacy
The purpose of this study is to advance the evidence base regarding methods for facilitating informed decisions among patients with knee and hip osteoarthritis by comparing DVD and online formats of decision aids for these…
- Trial name
- NCT01618097
- Testing
- DVD Decision Aid, Internet Based Decision Aid
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- Duke University
Osteoarthritis
A Study of the Efficacy and Safety of VX-150 in Subjects With Osteoarthritis of the Knee
The Primary objective of this study is to evaluate the efficacy of VX-150 in the treatment of osteoarthritis pain
- Trial name
- NCT02660424
- Testing
- VX-150
- Where
- 12 sites in United States
- Volunteers
- 124 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Knee Injuries, Anterior Cruciate Ligament Rupture
Stopping OsteoARthritis After an ACL Tear
By 2040, 25% of Canadians will have osteoarthritis, a disabling joint condition. Most people think osteoarthritis only affects older adults, but 50% of the 700,000 Canadian youth who hurt their knee playing sports annually will…
- Conditions
- Knee Injuries, Anterior Cruciate Ligament Rupture, Osteoarthritis, Knee
- Trial name
- SOAR (NCT06195423)
- Testing
- Stop OsteoARthritis (SOAR) program, Living Well after ACLR program
- Where
- 2 sites in Canada
- Volunteers
- 210 people
- Sponsor
- University of British Columbia
Rheumatoid Arthritis, Atherosclerotic Ischemic Disease
Coronary Computed Tomography Angiography In Rheumatoid Arthritis Study
The Coronary Computed Tomography Angiography in Rheumatoid Arthritis study is part of the multinational, prospective, observational Autoimmunity and Atherosclerosis in Rheumatic Diseases cohort (https://atacc-rd.com) that…
- Conditions
- Rheumatoid Arthritis, Atherosclerotic Ischemic Disease, Pulmonary Disease, Depressive Disorder
- Trial name
- COTIRA (NCT07363980)
- Where
- 4 sites in Denmark
- Volunteers
- 4,000 people
- Sponsor
- Ellen Margrethe Hauge
Osteoarthritis, Rheumatoid Arthritis
A Prospective, Clinical Investigation of the Vanguard 360 Revision Knee
The purpose of this study is to evaluate performance of the Vanguard 360 revision knee system utilizing offset on either the tibial component, femoral component, or both in terms of the restoration of mechanical alignment…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Post Traumatic Deformity
- Trial name
- NCT01542580
- Testing
- Vanguard SSK 360 with PS Bearing, Vanguard SSK 360 with PSC bearing, Vanguard DA 360
- Where
- 12 sites in United States, Belgium and 6 more
- Volunteers
- 255 people
- Sponsor
- Zimmer Biomet
Knee Osteoarthritis
Reinforcement of Placebo Response in Knee Osteoarthritis: A Randomised Trial
Saline intra-articular injections used as placebo treatments have been shown to provide pain relief in knee osteoarthritis (OA) It has further been shown that beneficial effects can be induced merely by having a conversation with…
- Trial name
- NCT05225480
- Testing
- Illness perception conversation, research motivation conversation
- Where
- Denmark
- Volunteers
- 103 people
- Sponsor
- Frederiksberg University Hospital
Systemic Lupus Erythematosus
Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dehydroepiandrosterone in Women With Active Systemic Lupus Erythematosus
OBJECTIVES: I. Evaluate the safety and efficacy of synthetic dehydroepiandrosterone, GL701, in women with active systemic lupus erythematosus.
- Trial name
- NCT00004662
- Testing
- dehydroepiandrosterone
- Volunteers
- 300 people
- Sponsor
- National Center for Research Resources (NCRR)
Hallux Limitus
Hallux Limitus Treated With Dynamic Splinting: A Randomized, Controlled Trial
The purpose of this study is to regain range of motion of the great toe with dynamic splinting which will help reduce great toe's pain and swelling.
- Trial name
- NCT00717691
- Testing
- Metatarsophalangeal Extension Dynasplint System, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Dynasplint Systems, Inc.
Gout
Evaluate the Efficacy and Safety of Arhalofenate for Preventing Flares and Reducing Serum Uric Acid in Gout Patients
The purpose of this study is to determine whether arhalofenate is effective in preventing flares and reducing serum uric acid in gout patients.
- Trial name
- NCT02063997
- Testing
- Arhalofenate 600 mg, Allopurinol 300 mg, Colchicine 0.6 mg
- Where
- 56 sites in United States, Canada and 1 more
- Volunteers
- 248 people
- Sponsor
- Gilead Sciences
Osteoarthritis (OA)
Effect of Chair Yoga on Elders With Osteoarthritis
The current study is a two-arm randomized controlled clinical trial to test the feasibility of recruiting, randomizing, and having older adults with osteoarthritis (OA) adhere to and safely complete the 8-week Sit 'N' Fit Chair…
- Trial name
- NCT02113410
- Testing
- Sit 'N' Fit Chair Yoga (SNFCY), Health Education Program (HEP)
- Where
- 2 sites in United States
- Volunteers
- 131 people
- Sponsor
- Florida Atlantic University
Patellofemoral Pain Syndrome
Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome
Patellofemoral pain syndrome (PFPS) is a common knee disorder affecting physically active people. Despite the growing base of support for the early introduction of hip strengthening exercises into the rehabilitation of PFPS…
- Trial name
- NCT00445224
- Testing
- Hip Progressive Resistive Exercise, Quad Progressive Resistive Exercises
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Timothy Uhl
Gout
Tight Control of Gouty Arthritis Compared to Usual Care
Gout is caused by a reaction to urate crystals that results in attacks of severe joint pain. Medicines that lower urate levels can prevent gout flares, however it takes time for this benefit to be felt, and paradoxically starting…
- Trial name
- TICOGA (NCT05507723)
- Testing
- Treat-to-target, Usual Care
- Where
- United Kingdom
- Volunteers
- 125 people
- Sponsor
- University of Edinburgh
Sjogren's Syndrome
Analyse of Inflammatory Activity of Sjögren's Syndrome on 68Ga-FAPI PET-CT
Sjögren's syndrome (SS) is a chronic autoimmune disease primarily affecting the salivary and lacrimal glands, leading to symptoms of dryness. Assessing the inflammatory activity is crucial for guiding treatment.
- Trial name
- NCT07062523
- Testing
- 68Ga-FAPI
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Juvenile Idiopathic Arthritis (JIA)
Withdrawal Versus Continued TNF Inhibitor Monotherapy Treatment in Children With Inactive Juvenile Idiopathic Arthritis
The goal of this clinical trial is to learn whether children and adolescents with juvenile idiopathic arthritis (JIA) who have had inactive disease for a long time can safely discontinue treatment with a tumour necrosis factor…
- Trial name
- The Treat-JIA (NCT07904780)
- Testing
- Adalimumab, Etanercept, Golimumab
- Where
- 3 sites in Norway
- Volunteers
- 90 people
- Sponsor
- Oslo University Hospital
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