Clinical trials: Articular Disease
Knee Osteoarthritis, Obesity
A Study of Econoglutide Injection in Obese Participants With Knee Osteoarthritis (KOA)
The main purpose of the study is to evaluate the efficacy and safety of ecnoglutide injections versus placebo in obese participants with KOA.
- Trial name
- NCT07734311
- Testing
- Ecnoglutide Injection
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Hangzhou Sciwind Biosciences Co., Ltd.
Tinnitus, TMJ
Treatment of Temporomandibular Joint Disorders With a Stabilizing Occlusal Splint in Somatosensory Tinnitus
This clinical trial aims to investigate whether treatment of temporomandibular joint disorder with a stabilizing occlusal splint is justified to alleviate somatosensory tinnitus.
- Conditions
- Tinnitus, TMJ, Temporomandibular Disorders (TMD)
- Trial name
- NCT07211711
- Testing
- Stabilizing occlusal splint
- Where
- Brazil
- Volunteers
- 63 people
- Sponsor
- University of Sao Paulo General Hospital
Rheumatoid Arthritis
SBD121, a Synbiotic Medical Food for RA Management
The aim of this randomised, double-blind, placebo controlled clinical food trial is to determine if the medical food SBD121 Synbiotic (prebiotic and probiotic) will aid in the dietary management of symptoms of early rheumatoid…
- Trial name
- NCT06005220
- Testing
- SBD121
- Where
- 22 sites in Australia, Bulgaria and 2 more
- Volunteers
- 143 people
- Sponsor
- Solarea Bio, Inc
Knee Osteoarthritis (Knee OA), Knee Pain Chronic
Advanced Brain Imaging-TKA (fMRI-TKA)
Knee replacement surgery is a common and effective treatment for pain and mobility loss, yet up to 1 in 5 patients remain dissatisfied after surgery due to ongoing pain or difficulty with daily activities.
- Conditions
- Knee Osteoarthritis (Knee OA), Knee Pain Chronic, Brain Network Connectivity, Patient Satisfaction
- Trial name
- fMRI-TKA (NCT07464080)
- Testing
- fMRI Brain Scan
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ottawa Hospital Research Institute
Osteoarthritis
Subject Insights to Understand the Hand Osteoarthritis (HOA)
Osteoarthritis (OA) is a degenerative joint disease which causes joints to become painful and stiff. HOA is the second most common form of OA and is characterized by stiffness, joint pain and inflammation and tenderness in the…
- Trial name
- NCT03271203
- Testing
- Michigan Hand Outcomes Questionnaire, Real-time data capture app
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- GlaxoSmithKline
Rheumatoid Arthritis
Effects of Kinesiotaping for Hands Function in Rheumatoid Arthritis
The aim of this research is to compare the effects of I-shape and fan shape kinesiotape techniques on pain, range of motion, grip strength and ADLs of patients with Rheumatoid Arthritis.
- Trial name
- NCT05039242
- Testing
- Conventional Physical Therapy), Kinesiotaping with I shaped application, Kinesiotaping with Fan-shaped Application
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Riphah International University
Shoulder Impingement Syndrome, Subacromial Impingement Syndrome
Treatment Using 448 kHz CRMRF in Subacromial Syndrome.
The purpose of this study is to assess the effectiveness of 448 kHz capacitive resistive monopolar radiofrequency in the treatment of subacromial syndrome.
- Trial name
- CRMRF (NCT04255186)
- Testing
- Thermal 448 kHz Capacitive Resistive Monopolar Radiofrequency, Subthermal 448 kHz Capacitive Resistive Monopolar Radiofrequency
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- University of Castilla-La Mancha
Rheumatoid Arthritis
Inflammation and the Heart
Studies have shown that people with rheumatoid arthritis (RA) have a higher rate of heart disease than people that do not have RA. we believe this is caused by the inflammation produced by RA.
- Trial name
- NCT01589770
- Testing
- cardiac Magnetic Resonance imaging
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Knee Arthritis Osteoarthritis
Comparing Pain Science Education to Biomedical Education for People With Knee Osteoarthritis: A Randomized Controlled Trial
Knee osteoarthritis (OA) is a common cause of pain and disability in older adults. Many people with knee OA believe that pain is primarily caused by joint damage or "wear and tear." These beliefs may contribute to fear of…
- Trial name
- NCT07823673
- Testing
- Pain Science Education, Biomedical Education
- Volunteers
- 82 people
- Sponsor
- McMaster University
Rheumatoid Arthritis
An Open-Label Study of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Active Rheumatoid Arthritis
This open-label, single-arm study will evaluate the efficacy and safety of tocilizumab in patients with active moderate to severe rheumatoid arthritis.
- Trial name
- NCT01951170
- Testing
- Tocilizumab
- Where
- 10 sites in Australia
- Volunteers
- 52 people
- Sponsor
- Hoffmann-La Roche
Shoulder Pain, Shoulder Impingement Syndrome
Shoulder Kinematics and Muscle Activation in Sport Climbers With Shoulder Pain
Sport climbing has recently become a highly popular sport and was included in the Summer Olympic Games 2021. Shoulder injury accounts for 15 to 20 percent of all sport climbing injuries, and it is the third most common problems…
- Trial name
- NCT05139654
- Testing
- Arm elevation in the scapular plane, Pull up with gymbar, Pull up with fingerboard
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Osteoarthritis
An Efficacy and Safety Study of Transdermal Therapeutic System (TTS)-Fentanyl in Participants With Osteoarthritis
The purpose of this study is to evaluate the efficacy and safety of Transdermal Therapeutic System (TTS)-fentanyl patch (transdermal patch containing a drug that is put on the skin so the drug will enter the body through the…
- Trial name
- NCT01774929
- Testing
- TTS-fentanyl
- Where
- Thailand
- Volunteers
- 35 people
- Sponsor
- Janssen-Cilag Ltd.,Thailand
Rheumatoid Arthritis
BIIB023 (Anti-TWEAK) in Subjects With Rheumatoid Arthritis
Phase I study designed to determine the safety and tolerability of a single dose of BIIB023 administered intravenously versus placebo to subjects with RA.
- Trial name
- NCT00771329
- Testing
- BIIB023
- Where
- 6 sites in United States, Russia
- Volunteers
- 53 people
- Sponsor
- Biogen
Shoulder Arthritis
Study on Shoulder Arthritis Treatment With Intra-articular Injections of Autologous Bone Marrow Aspirate.
Treatment of isolated osteoarthritis of the glenohumeral joint at the initial stages involves the use of numerous conservative or arthroscopic treatments with uncertain results and, upon their failure, the current solution for…
- Trial name
- Stemshoulder (NCT04308213)
- Testing
- Marrow Cellution System
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Clinico Humanitas
Osteoarthritis, Knee
Oxford Partial Knee Replacement. A Randomized Clinical Trial of Three Implant Types
The purpose of this scientific study is to clarify whether there is a relationship between the appearance of radiolucent lines in bone-cement interphase of the tibial component of the different models of the Oxford Uni Knee…
- Trial name
- NCT00679120
- Testing
- Oxford Uni Knee
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- University of Aarhus
Condition Angle, Angular Velocity, Linear Velocity, Moment, Ground Reaction Force, Hip Joint, Knee Joint, Ankle Joint
A Comparison of the Analysis of the Force on the Supporting Legs of Female Athletes of Different Levels Playing Football
In this study, we grouped athletes into different training levels, and tested the force on the supporting legs of female athletes at different times when they kicked the ball.
- Trial name
- NCT04743882
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Arthropathy of Hip
Short-Term Clinical Outcome of Total Hip Arthroplasty Using Larger Diameter of 4th Generation Ceramic Bearing
The primary objectives of this clinical study include: Assess the rate of dislocation and fracture of THA using the new (the 4th generation) ceramic implants.
- Trial name
- NCT01103882
- Where
- 4 sites in South Korea
- Volunteers
- 277 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee
Reaching Exercise Goals: Comparison of Exercise Means in Patients With Knee Osteoarthritis
The primary objective is to evaluate water based treadmill exercise, land based treadmill exercise, and upright cycling in meeting American College of Sports Medicine exercise goals for moderate exercise.
- Trial name
- NCT01359124
- Testing
- Exercise Cycle, Land-based Treadmill, Water-based Treadmill
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Milton S. Hershey Medical Center
Osteoarthritis, Rheumatoid Arthritis
The Standard Care Versus Celecoxib Outcome Trial
The Standard Care versus Celecoxib Outcome Trial (SCOT) is a large streamline safety study designed to compare the cardiovascular safety of celecoxib versus traditional non-selective Non Steroidal Anti-Inflammatory Drug (NSAID)…
- Trial name
- SCOTLSSS (NCT00447759)
- Testing
- Celecoxib, Diclofenac
- Where
- 10 sites in Denmark, Netherlands and 1 more
- Volunteers
- 7,297 people
- Sponsor
- University of Dundee
Psoriatic Arthritis
Validation of Handheld Ultrasound Devices in Rheumatology
The goal of this clinical trial is to test the concurrent validity of the Clarius handheld ultrasound devices versus gold-standard device to detect characteristic features of healthy and rheumatic joints in adults Psoriatic…
- Trial name
- NCT06580886
- Testing
- Ultrasound
- Where
- 3 sites in United States, Canada
- Volunteers
- 30 people
- Sponsor
- Ottawa Hospital Research Institute
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