Clinical trials: Articular Disease
Wear of Articular Bearing Surface of Internal Prosthetic Joint, Infection Prosthetic
Percutaneous Punch Biopsy for Diagnosis of Septic and Aseptic Prosthetic Joint Failure
The aim of the superiority study is to establish a reproducible, minimally invasive, cost-effective way of sample collection for microbiological and pathomorphological processing in a clinical setting with avoidance of…
- Conditions
- Wear of Articular Bearing Surface of Internal Prosthetic Joint, Infection Prosthetic, Infections Joint Prosthetic, Prosthetic Joint Infection
- Trial name
- SHARP (NCT04620395)
- Testing
- Punch biopsy
- Where
- Germany
- Volunteers
- 132 people
- Sponsor
- Vivantes Netzwerk für Gesundheit GmbH
Arthritis, Rheumatoid
Observational Study of Meloxicam in Any Labeled Indication
Evaluation on the amelioration of symptom intensity of the indication and to evaluate drug tolerability.
- Trial name
- NCT02182739
- Testing
- Meloxicam
- Volunteers
- 13,039 people
- Sponsor
- Boehringer Ingelheim
Gout
Safety and Pharmacodynamics of SEL-212 (Pegsiticase + SEL-110) in Subjects With Elevated Blood Uric Acid Levels
This Study will first evaluate the safety and pharmacokinetics of a single intravenous dose of SEL-110, a nanoparticle containing rapamycin, in subjects with elevated blood uric acid levels.
- Trial name
- NCT02648269
- Testing
- SEL-110, SEL-212, SEL-037
- Where
- 6 sites in United States
- Volunteers
- 63 people
- Sponsor
- Selecta Biosciences, Inc.
Osteoarthritis, Knee, Meniscus; Degeneration
High Tibial Osteotomy With/Without Arthroscopy.
This study will compare Hight Tibial Osteotomy with or without arthroscopically repair intra-articular knee lesions in patients with early stages of Osteoarthritis.The purpose of this study is evaluate if addition of arthroscopy…
- Trial name
- NCT05128851
- Testing
- HTO, Arthroscopy treatment, Micro fractures
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre of Postgraduate Medical Education
Knee Osteoarthrosis
Use of Adipose Tissue Derived Mesenchymal Stem Cells for Knee Osteoarthrosis
Adipose tissue derived Mesenchymal Stem cells (ATMSC) will be injected in patients diagnosed with Knee osteoarthrosis
- Trial name
- NCT02966951
- Testing
- Adipose tissue derived mesenchymal stem cell
- Where
- Jordan
- Volunteers
- 10 people
- Sponsor
- Hanan Jafar
Rheumatoid Arthritis
Development of a Normative Database for Rheumatoid Arthritis (RA) Imaging With Tc99m Tilmanocept
This study will establish a normative database of Tilmanocept Uptake Values (TUVjoint) in healthy controls age-matched to the RA population.
- Trial name
- NCT04947137
- Testing
- Tc99m tilmanocept
- Where
- 7 sites in United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Navidea Biopharmaceuticals
Prostate Cancer
Trial Comparing Irradiation Plus Long Term Adjuvant Androgen Deprivation With GnRH Antagonist Versus GnRH Agonist Plus Flare Protection in Patients With Very High Risk Localized or Locally Advanced Prostate Cancer
The primary objective of the trial is to assess if GnRH antagonists in combination with external beam radiation therapy improve progression free survival (progression that can be biological, clinical, or death) compared to GnRH…
- Trial name
- PEGASUS (NCT02799706)
- Testing
- Degarelix, approved GnRH agonist, Radiotherapy
- Where
- 39 sites in Belgium, Denmark and 6 more
- Volunteers
- 885 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Hemi Knee Arthroplasty, Patello-femoral Osteoarthritis
Evaluation of Orthopedic Knee Measurement Using Lunar iDXA
This study is to compare scans of the knee performed using new software designed specifically to look at the knee joint with those performed using approved software designed for scans of the hip.
- Trial name
- NCT01348958
- Testing
- iDXA knee software
- Where
- New Zealand
- Volunteers
- 36 people
- Sponsor
- GE Healthcare
Arthritis
Staying Positive With Arthritis Study
Arthritis is a painful, disabling condition that disproportionately affects African Americans. Existing arthritis treatments yield only small to moderate improvements in pain and are not effective at reducing racial disparities…
- Trial name
- SPA (NCT02223858)
- Testing
- Positive Activities (PA) Program, Attention Control (AC) Program
- Where
- 2 sites in United States
- Volunteers
- 360 people
- Sponsor
- VA Office of Research and Development
Shoulder Pain
Sleeper Stretch in CrossFit Participants
The purpose of this study is to compare the efficacy of the sleeper stretch in improving shoulder range of motion, strength and upper body performance in CrossFit athletes.
- Trial name
- NCT06720155
- Testing
- Sleeper stretch, Standard workout
- Where
- 2 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Rheumatoid Arthritis
Fexofenadine in Patients With Active Rheumatoid Arthritis
Rheumatoid arthritis (RA) is an inflammatory autoimmune polyarthritis affecting ∼1% of the world population, resulting in the loss of joint function and progressive structural damage in affected joints.
- Trial name
- NCT05264025
- Testing
- Fexofenadine
- Where
- 2 sites in Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- October 6 University
Knee Osteoarthritis
GAE Using Embosphere Microspheres vs Corticosteroid Injections for Treatment of Symptomatic Knee OA (MOTION)
This multicenter, prospective, interventional trial is designed to assess the outcome of subjects with symptomatic knee osteoarthritis (OA) that are randomized to treatment with either genicular artery embolization (GAE) using…
- Trial name
- MOTION (NCT05818150)
- Testing
- Embosphere Microspheres, Corticosteroid injection
- Where
- 27 sites in United States, Australia and 4 more
- Volunteers
- 264 people
- Sponsor
- Merit Medical Systems, Inc.
Patellofemoral Pain Syndrome
Popliteus Muscle Release Versus Patellofemoral Mobilization in Patellofemoral Pain Syndrome
This study will be conducted to compare the effect of popliteus muscle release and patellofemoral mobilization on pain intensity, function, and quadriceps muscle strength in patients with patellofemoral pain syndrome?
- Trial name
- PFPS (NCT07698704)
- Testing
- Popliteus Muscle Release, Patellofemoral Mobilization, traditional therapy
- Volunteers
- 48 people
- Sponsor
- Cairo University
Knee Osteoarthritis
Gait Analysis in Patients Underwent Total Knee Arthroplasty With a Medial Pivot Design.
The purpose of the present pilot study is to evaluate, through gait analysis and rating scales, the functional outcome during the execution of motor tasks with high functional demand such as walking on an unstable surface, stair…
- Trial name
- NCT04244838
- Testing
- Gait Analysis
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Istituto Ortopedico Rizzoli
Dupuytren&Amp;#39;s Contracture, Dupuytren&Amp;#39;s Fasciectomy
Preoperative Serial Casting, Education, and Therapy for Dupuytren's Contracture
We are running a small study to test whether a special type of therapy - including casting, stretching, and massage - might help improve recovery after Dupuytren's Fasciectomy.
- Conditions
- Dupuytren&Amp;#39;s Contracture, Dupuytren&Amp;#39;s Fasciectomy, Dupuytren&Amp;#39;s Disease
- Trial name
- PRESCET (NCT07024576)
- Testing
- Preoperative casting intervention
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Bournemouth University
Knee Osteoarthritis
Trial Evaluating multimOdal toPical Cream In CompArison to pLacebo (TOPICAL)
Randomized controlled trial regarding the efficacy of a multimodal topical analgesic, Multiprofen, in comparison to placebo cream treatment on knee pain and function in patients with knee osteoarthritis.
- Trial name
- TOPICAL (NCT03199417)
- Testing
- Multiprofen
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Sacroiliac Joint Somatic Dysfunction
Comparison of CornerLoc SI Joint Stabilization and Steroid Injections for Sacroiliac Joint Dysfunction
This study has been designed to compare the safety and effectiveness of the CornerLoc™ SI Joint Stabilization System to intra-articular sacroiliac joint steroid injection in patients with refractory sacroiliac joint dysfunction.
- Trial name
- COVI (NCT04218838)
- Testing
- CornerLoc SI Joint Stabilization Procedure, Intra-articular Sacroiliac Joint Steroid Injection
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- CornerLoc
Osteoarthritis
Safety and Clinical Effectiveness of A3 SVF in Osteoarthritis
To purpose of this study is to determine if treatment with SVF (Stromal Vascular Fraction) has an effect on pain and inflammation associated with Osteoarthritis.
- Trial name
- NCT01947348
- Testing
- treatment with A3 SVF
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Institute of Regenerative and Cellular Medicine
Temporomandibular Joint Osteoarthritis
Efficacy of Autologous Conditioned Serum in Temporomandibular Joint Disorder
Temporomandibular joint (TMJ) disorders are health conditions that can occur at any age and are recognized as the most common cause of chronic pain, affecting 5-12% of the population.
- Trial name
- NCT06839326
- Testing
- Autologous Conditioned Serum, Genesis Biyomedikal, Sanakin®-Acrs produce, Platelet Rich Plasma, Control Group/ Only Arthrocentesis
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Batman University
Temporomandibular Joint Disorders, Rheumatoid Arthritis
Temporomandibular Joint in Patients With Rheumatoid Arthritis
the investigators study aimed to evaluate temporomandibular joint involvement in rheumatoid arthritis patients and healthy individuals 142 participants were recruited in two groups: 72 patients with Rheumatoid Arthritis (RA), and…
- Trial name
- NCT06134726
- Testing
- seropositivity of rheumatoid factor
- Where
- Syria
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Syrian Private University
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