Clinical trials: Articular Disease
Autism Spectrum Disorder (ASD), Joint Attention Impairment
Social Attention in ASD and TD Children
To examine whether the spatiotemporal organization of gaze strategies differs between children with autism spectrum disorder (ASD) and typically developing (TD) children during a staged joint attention interaction, and to…
- Trial name
- NCT07583615
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Chronic Shoulder Pain, Pericapsular Nerve Group Block (PENG Block)
Ultrasound-Guided PENG Block for Chronic Shoulder Pain
The purpose of this prospective, observational study is to evaluate the clinical and functional outcomes of ultrasound-guided Pericapsular Nerve Group (PENG) block in patients suffering from chronic shoulder pain.
- Conditions
- Chronic Shoulder Pain, Pericapsular Nerve Group Block (PENG Block), Frozen Shoulder, Bursitis
- Trial name
- NCT07607691
- Testing
- Lidocaine and Dexamethasone for PENG Block
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara City Hospital Bilkent
Temporomandibular Joint Disc Displacement, With Reduction, Temporomandibular Disorders (TMD)
TMJ Arthroscopic Lysis and Lavage Compared to Operative Arthroscopy in Disc Displacement With Reduction.
The goal of this clinical trial is to compare the intervention arthroscopic lysis and lavage to the intervention operative arthroscopy in treating disabling and painful temporomandibular joint disc displacement with reduction.
- Trial name
- ALLOAA (NCT06782191)
- Testing
- Arthroscopic lysis and lavage, Operative arthroscopy
- Where
- Sweden
- Volunteers
- 96 people
- Sponsor
- Karolinska Institutet
Inflammation, Sjogren's Syndrome
Superb Microvascular Imaging Ultrasonography of Lacrimal Gland in Patients With Sjögren Syndrome
A prospective study will be conducted to evaluate inflammatory activity in lacrimal glands due to Sjögren's syndrome on Superb Microvascular Imaging (SMI), gray scale ultrasound (US), color Doppler US and Power Doppler US.
- Conditions
- Inflammation, Sjogren's Syndrome, Gland; Inflammation
- Trial name
- SMI (NCT05689749)
- Testing
- Superb Microvascular Imaging (SMI) (Toshiba)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Rheumatoid Arthritis
Efficacy and Safety Study of BMS-986142 in Patients With Moderate to Severe Rheumatoid Arthritis
The purpose of this study is to determine whether the study drug, BMS-986142, is safe and effective in treating moderate to severe rheumatoid arthritis in subjects with an inadequate response to methotrexate or methotrexate and…
- Trial name
- NCT02638948
- Testing
- BMS-986142, Methotrexate
- Where
- 104 sites in United States, Argentina and 15 more
- Volunteers
- 508 people
- Sponsor
- Bristol-Myers Squibb
TMJ Pain
Topical Treatment for TMJ Arthralgia
The goal of this clinical trial is to evaluate the efficacy of topical 2.5% hydrocortisone in TMJ arthralgia. The main questions it aims to answer are: How does pain reduction compare? How does improvement in jaw function…
- Trial name
- NCT05816226
- Testing
- Hydrocortisone 2.5%, Diclofenac 1% topical
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of the Pacific
Knee Osteoarthritis
The Bone Cement Penetration in Medial Fixed-bearing Unicompartmental Knee Arthroplasty
During Medial Fixed-bearing Unicompartmental Knee Arthroplasty, pulsed lavage combined with moderate pressurization achieves deeper cement penetration into cancellous bone than manual rinsing, optimizing the bone-cement-implant…
- Trial name
- NCT07866378
- Testing
- unicompartmental knee arthroplasty
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Tianjin Union Medical Center
Hip Osteoarthritis, Osteoarthritis
Development and Evaluation of a Web Based Decision Aid for Patients With Hip Osteoarthritis
The main goal of this study is assess the effectiveness of a PtDA for patients with hip osteoarthritis
- Trial name
- NCT04241978
- Testing
- Patient Decision Aid (PtDA), Brochure with general information about osteoarthritis
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- Servicio Canario de Salud
Knee Osteoarthritis (Knee OA)
Comparison of SVF Injection With and Without Microfracture in Moderate Knee Osteoarthritis
This prospective, randomized controlled clinical trial aims to evaluate the clinical and radiological effects of combining stromal vascular fraction (SVF) therapy with arthroscopic microfracture in patients with knee…
- Trial name
- NCT07112885
- Testing
- Arthroscopic Microfracture Combined with Autologous SVF Injection, Arthroscopic Debridement Followed by Autologous SVF Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Osteoarthritis, Knee, Psychological Disorder
Total Knee Arthroplasty Combined With Psychological Intervention for Patients With Psychological Disorders
Objective To evaluate the incidence of psychological problems in total knee arthroplasty (TKA) patients and examine whether perioperative psychological intervention can improve the outcomes of and patient satisfaction with TKA.
- Conditions
- Osteoarthritis, Knee, Psychological Disorder, Psychological Intervention, Satisfaction
- Trial name
- NCT03715608
- Testing
- Psychological Intervention
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Osteoarthritis, Knee
The Effect of Exercise on Serum Levels of Collagen and Proteoglycan in Patients With Knee Osteoarthritis
The aim of EFEX-OA-02 is to explore how running, cycling, exercise simulation and resting acutely influence collagen and proteoglycan homeostasis in OA, as reflected by changes in collagen and proteoglycan levels in urine and…
- Trial name
- EFEX-OA-02 (NCT04542668)
- Testing
- Cycling then running, Running then cycling, Inotropy
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Nordic Bioscience A/S
Knee Osteoarthritis, Effusion Synovial
Methotrexate in the Treatment of Advanced Knee Osteoarthritis With Effusion-synovitis
This multicentre randomized placebo-controlled clinical trial aims to evaluate whether methotrexate (MTX) has effects of relieving symptoms and reducing inflammation on advanced knee osteoarthritis (OA) with inflammatory…
- Conditions
- Knee Osteoarthritis, Effusion Synovial, Knee Pain
- Trial name
- NCT03815448
- Testing
- Methotrexate
- Where
- 11 sites in China
- Volunteers
- 215 people
- Sponsor
- Zhujiang Hospital
Arthritis, Psoriatic
Study of the Safety and Efficacy of Adalimumab in Subjects With Moderate to Severely Active Psoriatic Arthritis Subjects With Inadequate Response to Disease Modifying Anti-Rheumatic Drug Therapy
Multicenter Study of the Safety and Efficacy of Adalimumab in Subjects with Moderate to Severely Active Psoriatic Arthritis Subjects with Inadequate Response to Disease Modifying anti-Rheumatic Drug Therapy
- Trial name
- NCT00646178
- Testing
- adalimumab
- Volunteers
- 102 people
- Sponsor
- Abbott
Hip Dysplasia
Exercise and Patient Education Compared With Usual Care in Patients With Hip Dysplasia
This effectiveness trial will investigate if patients with hip dysplasia randomised to exercise and patient education have a different mean change in self-reported pain measured by the Copenhagen Hip and Groin Outcome Score…
- Trial name
- MovetheHip (NCT04795843)
- Testing
- Exercise and patient education, Usual Care
- Where
- 2 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- University of Aarhus
Noonan Syndrome
Joint and Hematologic Disorders of Noonan Syndrome: French Descriptive Cross-sectional Study
Noonan's syndrome is a rare genetic disease, estimated to be between 1: 1000 to 1: 2500 and characterized by cardiothoracic malformations, sometimes mental retardation, but also by hematologic abnormalities and joint involvement.
- Trial name
- NOORHA (NCT06550635)
- Where
- 4 sites in France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Brest
Total Knee Arthroplasty, Osteoarthritis
Kinematic and Mechanical Alignment Randomized Trial
Knee replacement surgery is the second most common surgery in Canada. People who have very painful knee arthritis usually receive a knee replacement where the surgeon aims to make everyone's knee as straight as possible (called…
- Trial name
- KMART (NCT06787417)
- Testing
- Restricted Kinematically-aligned Arthroplasty, Mechanically-Aligned Arthroplasty
- Where
- Canada
- Volunteers
- 260 people
- Sponsor
- McMaster University
Niu Bang Zi Pill, Rheumatoid Arthritis
The Efficacy of the Traditional Chinese Medicine Niubang Pill Combined With Methotrexate on Active Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic, systemic, inflammatory autoimmune disease that results in the destruction of joints, connective tissues, muscle, tendons and fibrous tissue.
- Trial name
- NCT03173040
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Cui xuejun
Subacromial Impingement Syndrome
Comparison of Supervised Rehabilitation and Home Exercise Programs in Subacromial Impingement Syndrome
This randomized controlled trial aims to compare the effectiveness of physiotherapist-supervised rehabilitation and home exercise programs in individuals with subacromial impingement syndrome (SAIS).
- Trial name
- SAIS-REHAB (NCT07568340)
- Testing
- Supervised Rehabilitation Program, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Rheumatoid Arthritis, Autoimmune Rheumatologic Disease
COvid-19 Vaccine Booster in Immunocompromised Rheumatic Diseases
People living with Systemic autoimmune rheumatic diseases (SARDs) face a new and urgent dilemma: immunosuppression increases risk for worse COVID-19 infection, yet an immune stimulation, such as vaccination, could re-activate…
- Conditions
- Rheumatoid Arthritis, Autoimmune Rheumatologic Disease, Systemic Lupus Erythematosus, Systemic Vasculitis
- Trial name
- COVBIRD (NCT05236491)
- Testing
- COVID-19 vaccine
- Where
- 2 sites in Canada
- Volunteers
- 287 people
- Sponsor
- Paul R Fortin
Hip Osteoarthritis
Comparison of the Effect of Intra Articular Steroid Injection and Pericapsular Nerve Group Block for Hip Osteoarthritis
The most common cause of hip joint dysfunction in the elderly is degenerative osteoarthritis of the hip. Innervation of the hip joint capsule is provided by the obturator nerve, the accessory obturator nerve, and the femoral…
- Trial name
- NCT05136248
- Testing
- intraarticular injection, peng block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Diskapi Teaching and Research Hospital
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