Clinical trials: Artificial
Sepsis, Abdominal Sepsis
Personalised Real-time Interoperable Sepsis Monitoring (PRISM)
The goal of this prospective observational study is to develop and utilize an Artificial Intelligence (AI) model for the prediction of postoperative sepsis in patients undergoing abdominal surgery.
- Conditions
- Sepsis, Abdominal Sepsis, Infections, Clinical Deterioration
- Trial name
- PRISM (NCT06238180)
- Testing
- PRISM Tool
- Where
- Greece
- Sponsor
- Aisthesis Medical P.C.
Inflammatory Bowel Diseases
West Hertfordshire Inflammatory Bowel Disease Technology Study
A retrospective and prospective, observational, non-interventional, cohort study to develop quantitative metrics from tools used as standard of care when diagnosing, assessing and monitoring patients with inflammatory bowel…
- Trial name
- WHITS (NCT05000242)
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Perspectum
Breast Cancer
ThermoBreast - Non-contact Breast Cancer Imaging Using AI-enhanced Thermography.
Breast cancer is one of the most worrisome health concerns facing women. Early detection and active patient monitoring are crucial to survival. The chances of a cure are high when detected and treated in the early stages.
- Trial name
- ThermoBreast (NCT06266026)
- Testing
- ThermoBreast - AI-based evaluation of dynamic breast thermography imaging
- Where
- Germany
- Volunteers
- 28,000 people, healthy volunteers welcome
- Sponsor
- ThermoMind Ltd.
Magnetic Resonance Imaging, Cardiac Pacemaker, Artificial
Advisa MRI Clinical Study
The purpose of the Advisa MRI System clinical study is to confirm safety and effectiveness in the clinical MRI (Magnetic Resonance Imaging) environment when subjects receive MRI scans up to 2W/kg Specific Absorption Rate (SAR)…
- Trial name
- NCT01110915
- Testing
- Medtronic Advisa MRI Implantable Pulse Generator (IPG), Medtronic CapSureFix MRI™ active fixation MRI lead
- Where
- 37 sites in United States, Australia and 11 more
- Volunteers
- 269 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Dry Eye
Acute Comfort of Lubricant Eye Drops FID 112903
To evaluate the acute comfort and blurring profile between two artificial tears in dry eye patients.
- Trial name
- NCT00673855
- Testing
- Lubricant Eye Drops FID 112903, Optive Lubricant Eye Drops
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Alcon Research
Infertility Assisted Reproductive Technology, Infertility (IVF Patients)
Blastocyst AI Assisted Morphokinetics in ART
The goal of this observational study is to learn if embryo characteristics obtained via the recording of real-time embryo activity via 30-seconds video capture (e.g.: Embryo Morphokinetics) can correlate with known embryo outcome…
- Trial name
- AIM (NCT07611448)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Viable Biosciences
Cardiac Pacing, Artificial
Closed Loop Stimulation, Cognitive Performance, and Quality of Life in Pacemaker Patients
The purpose of this study is to compare the influence of accelerometer-based rate adaptation and Closed Loop Stimulation on cognitive performance and quality of life in pacemaker patients.
- Trial name
- COGNITION (NCT00323661)
- Testing
- Rate-adaptive pacemaker: accelerometer, Rate-adaptive pacemaker: Closed Loop Stimulation
- Where
- 55 sites in Australia, Austria and 8 more
- Volunteers
- 405 people
- Sponsor
- Biotronik SE & Co. KG
Peripheral Nerve Injuries
Performance Study of an Artificial Nerve Guide (Reaxon® Nerve Guide) to Treat Digital Nerve Lesions
The purpose of this clinical investigation is to confirm the medium- and long-term safety and performance of the chitosan-based nerve guide (Reaxon® Nerve Guide) in comparison to an autologous nerve graft to bridge nerve defects…
- Trial name
- NCT02459015
- Testing
- Implantation
- Where
- 4 sites in Germany
- Volunteers
- 46 people
- Sponsor
- Medovent GmbH
Fracture
Clinical Validation of Boneview for FDA Submission
The goal of this clinical validation is to assess comparative performances of physicians with and without the assistance of BoneView for the diagnosis of fractures on radiographs.
- Trial name
- NCT04532580
- Testing
- Diagnosis of fracture on X-Ray Radiographs
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Gleamer
Ventricular Dysfunction, Left, Ventricular Function, Left
Federated Learning for Point-of-Care Cardiac Ultrasound
This prospective, multicenter study will evaluate a federated machine-learning system designed to analyze focused cardiac point-of-care ultrasound examinations.
- Conditions
- Ventricular Dysfunction, Left, Ventricular Function, Left, Echocardiography, Ultrasonography
- Trial name
- FL-POCUS (NCT07800962)
- Testing
- Focused Cardiac Point-of-Care Ultrasonography, FL-POCUS Federated Machine-Learning Analysis System
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Truway Health, Inc.
Ultrasound Imaging of Anatomical Structures, Nerve Block
Nerve and Plane Block Data Collection Study for the Development of Artificial Intelligence-assisted Software
The primary objective of this observational study is to acquire ultrasound images (raw data) from nerve and plane block regions to develop artificial intelligence-guided nerve block software (Nerveblox).
- Trial name
- NCT06375603
- Testing
- Ultrasound scans
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Smart Alfa Teknoloji San. ve Tic. A.S.
Colorectal Cancer
Safety and Efficacy of the Olympus CADe System in Real-time Colonoscopy
This is a prospective, multicenter, randomized Trial to assess the safety and efficacy of the Olympus Endoscopy Computer-Aided Detection (CADe) system, OIP-1, in the detection of colorectal neoplasia's during real-time…
- Trial name
- EuroCADe (NCT05943288)
- Testing
- OIP-1
- Where
- 6 sites in Belgium, Germany and 2 more
- Volunteers
- 850 people
- Sponsor
- Olympus Europe SE & Co. KG
Cervical Degenerative Disc Disease
Comparison of DISCOVER™ Artificial Cervical Disc and ACDF for Treatment of Cervical DDD (IDE Study)
This study is intended to treat patients with symptomatic degenerative disc disease at one level of the cervical spine. The patients will be randomized to the DISCOVER Artificial Cervical Disc (total disc replacement) or…
- Trial name
- NCT00432159
- Testing
- Cervical TDR, ACDF with plate
- Where
- 32 sites in United States, Australia and 1 more
- Volunteers
- 500 people
- Sponsor
- DePuy Spine
Skin Condition, Skin Abnormalities
Using an Artificial Intelligence Medical Device to Help Primary Care Practitioners Identify and Manage Skin Conditions (Tumor, Inflammatory, and Infectious Diseases) in Adult Patients at Pozuelo and Majadahonda Health Centers
The goal of this observational study is to learn if an artificial intelligence (AI) tool helps primary care practitioners better identify skin conditions.
- Conditions
- Skin Condition, Skin Abnormalities, Malignancy, Melanoma (Skin Cancer)
- Trial name
- NCT07429123
- Testing
- Primary care practitioners aided by Legit.Health Plus
- Where
- Spain
- Volunteers
- 131 people
- Sponsor
- AI Labs Group S.L
Glaucoma, Diabetic Retinopathy (DR)
"My Eyes, My Light": Amar Chokh, Amar Alo
Eye disease affects 2.2 billion people globally, which in turn adversely affects schooling, economic productivity, and participation in social life.
- Conditions
- Glaucoma, Diabetic Retinopathy (DR), Hypertensive Retinopathy, Cataract
- Trial name
- ACA2 (NCT07135570)
- Testing
- Multimodal Screening for Eye Disease, cataract surgery
- Where
- Bangladesh
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Data Yakka, Inc.
Type 1 Diabetes, T1D
DASH-Obesity: Explainable AI for Family-Centric Personalized Weight Control in Adolescents and Young Adults With Obesity and Chronic Conditions
This prospective single-arm feasibility study evaluates the Adhera Caring Digital Program for Obesity (ACDP-O), a family-centered digital health intervention designed to support adolescents and young adults with…
- Conditions
- Type 1 Diabetes, T1D, Obesity & Overweight, Obesity Type 2 Diabetes Mellitus
- Trial name
- DASH-Obesity (NCT07638345)
- Testing
- Adhera Caring Digital Program-Obesity (ACDP-O)
- Where
- Spain
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Adhera Health, Inc.
Cancer
One Million Cancer Treatment Months
The OMCAT Register aims to provide learning databases in cancer comprising both PRO data using PRO-React and "ground truth" (outcome data verified by the physician during patient examinations).
- Trial name
- OMCAT (NCT04531995)
- Testing
- CANKADO PRO-React Onco
- Where
- 4 sites in Germany
- Volunteers
- 166,000 people
- Sponsor
- Cankado GmbH
Low Ejection Fraction
Detection of Reduced Left Ventricular Ejection Fraction With Three-Lead ECG Using Artificial Intelligence
The main objectives of this study are to train and evaluate an algorithm that predicts whether an individual has an ejection fraction ≤ 40%, using heart sounds and a 3-lead ECG as inputs, as well as determine the impact of…
- Trial name
- NCT07270692
- Testing
- Eko digital stethoscopes
- Where
- India
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Eko Devices, Inc.
Symptomatic Cervical Disc Disease
SECURE®-C Cervical Artificial Disc Clinical Study/ SECURE-C Cervical Artificial Disc Postmarket Approval Study
The purpose of the pivotal IDE clinical study was to evaluate the safety and effectiveness of the SECURE®-C Cervical Artificial Disc for the treatment of symptomatic cervical disc disease at one level between C3 and C7, compared…
- Trial name
- NCT00882661
- Testing
- SECURE-C Cervical Artificial Disc, ASSURE Cervical plate and an allograft interbody spacer
- Volunteers
- 380 people
- Sponsor
- Globus Medical Inc
Dry Eye Syndromes, Keratoconjunctivitis Sicca
Efficacy and Safety Study of ATs in Patients With Dry Eye Syndrome
The purpose of this study is to determine whether artificial tears are safe and effective in the treatment of Dry Eye Syndrome.
- Trial name
- NCT00788229
- Testing
- AT01, AT02, AT03
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Dhp Korea Co., Ltd.