Clinical trials: Artificial
Cardiac Disease
PROSPECTIVE EVALUATION OF HEARTFOCUS
The study's objective is to evaluate if exams, performed with the HeartFocus software by novices, are of sufficient quality to visually analyze the left ventricular size, the left ventricular function, the right ventricular size…
- Trial name
- HF-01 (NCT05874128)
- Testing
- Using HeartFocus software with AI guidance (Novices), Using HeartFocus software without AI-guidance
- Where
- 2 sites in United States, France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- DESKi
Depression, Anxiety
Potency and Precision Investigation
The overarching goal of this study is to establish initial proof of mechanism for precision interventions in an adult population.
- Trial name
- PAPI (NCT06240091)
- Testing
- DISC-MA
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Woebot Health
Hypertension
Piloting Healthcare Coordination in Hypertension
The PRECISION study investigates the possibility of integrating a clinical decision support analytic intelligence into the clinical care flow at University of California San Francisco Medical Center (UCSF MC).
- Trial name
- PRECISION (NCT02988193)
- Testing
- optima4BP Medication Management
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Optima Integrated Health
Dry Eye
Acute Comfort of Lubricant Eye Drops FID 112903
To evaluate the acute comfort and blurring profile between two artificial tears in dry eye patients.
- Trial name
- NCT00673855
- Testing
- Lubricant Eye Drops FID 112903, Optive Lubricant Eye Drops
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Alcon Research
Bradycardia, Congestive Heart Failure
The EASYTRAK EPI Clinical Investigation
The purpose of this study is to assess the safety and effectiveness of the EASYTRAK EPI lead.
- Trial name
- EASYTRAK EPI (NCT00158925)
- Testing
- EASYTRAK EPI lead
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Scientific Corporation
Visual Acuity
Clinical Evaluation of Two Marketed Artificial Tears in Non-contact Lens Wearing Patients
This clinical study is a randomized, double-masked, cross-over, bilateral, 2 treatment x 2 period, dispensing 4-visit study with a 7-9 day washout period in between visits 2 and 3. The study will last approximately 3 months.
- Trial name
- NCT03466086
- Testing
- Test Eye Drops, Control Eye Drops
- Where
- United Kingdom
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Dry Eye
Acute Comfort of Lubricant Eye Drop FID 111421
To evaluate the acute comfort and blurring profile between two artificial tears products in dry eye patients
- Trial name
- NCT00673959
- Testing
- Lubricant Eye Drop FID 111421, Optive Lubricant Eye Drop
- Volunteers
- 20 people
- Sponsor
- Alcon Research
Cardiac Pacing, Artificial, Cardiac Pacemaker, Artificial
Optimize RV Selective Site Pacing Clinical Trial
The purpose of the Optimize RV study is to determine the long-term effect of selective site pacing. Selective site pacing refers to which area of the right ventricle the lead is placed.
- Trial name
- NCT00422669
- Testing
- Medtronic Dual-Chamber Pacemaker, Medtronic SelectSecure 3830 Lead
- Where
- 22 sites in United States, Canada and 4 more
- Volunteers
- 205 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Mitral Valve Insufficiency, Heart Valve Diseases
NeoChord TACT Post-Market Surveillance Registry
To monitor the long-term performance of the CE Marked NeoChord Artificial Chordae Delivery System
- Conditions
- Mitral Valve Insufficiency, Heart Valve Diseases, Heart Diseases, Cardiovascular Diseases
- Trial name
- NCT01784055
- Where
- 7 sites in France, Germany and 3 more
- Volunteers
- 126 people
- Sponsor
- NeoChord
Cervical Degenerative Disc Disorder
Post-Approval Study Protocol for the Simplify Cervical Artificial Disc
This study is intended to demonstrate the 5-year long-term safety and efficacy of the Simplify® Cervical Artificial Disc ("Simplify Disc") in subjects enrolled in the non-randomized Simplify Disc IDE study.
- Trial name
- NCT04630626
- Testing
- Simplify Disc, ACDF
- Where
- 15 sites in United States
- Volunteers
- 145 people
- Sponsor
- NuVasive
Dry Eye Syndrome
Evaluate the Safety and Efficacy of a New Artificial Tear for Use After LASIK Surgery
This study will evaluate the safety and efficacy of a new artificial tear for the treatment of dry eye that may occur after LASIK surgery
- Trial name
- NCT00544713
- Testing
- Carboxymethylcellulose and Glycerin based artificial tear, Carboxymethylcellulose
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Allergan
Vascular Function
Flow Mediated Dilation in Response to Black Tea
Research indicate that people who regularly drink tea have a reduced risk of stroke or heart disease. In a number of studies in which people that normally do not drink showed that their blood vessels function improved when the…
- Trial name
- T (NCT02273323)
- Testing
- Tea
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Unilever R&D
Keratoconjunctivitis Sicca
Tear Film Break-up Time After Instillation of Artificial Tears
This study is an exploratory trial evaluating the tear film break-up time after a single eye drop instillation of over-the-counter artificial tears.
- Trial name
- NCT00681265
- Testing
- glycerin, polyethylene glycol 400/propylene glycol
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Calm Water Therapeutics LLC
Dry Eye Disease (DED)
Efficacy and Safety of a New Artificial Tear Formulation Compared With Systane Ultra Multidose in Participants With Dry Eye Disease
The purpose of this study is to compare the efficacy and safety of a new artificial tear formulation (011516X) with Systane® Ultra Multidose for 90 days in participants with Dry Eye Disease (DED).
- Trial name
- NCT04393441
- Testing
- 011516X (New Artificial Tear Formulation), Systane Ultra Multidose, REFRESH PLUS®
- Where
- 26 sites in United States
- Volunteers
- 400 people
- Sponsor
- Allergan
Colorectal Cancer, Polyp of Colon
EAGLE Trial CADDIE Artificial Intelligence Endoscopy
The EAGLE study is a prospective randomized controlled multicenter parallel design trial, for the assessment of clinical performance of the CADDIE device and to confirm that the device performs as expected.
- Conditions
- Colorectal Cancer, Polyp of Colon, Adenoma Colon
- Trial name
- EAGLE (NCT05730192)
- Testing
- Colonoscopy with CADDIE, Standard Colonoscopy
- Where
- 8 sites in Germany, Italy and 2 more
- Volunteers
- 985 people
- Sponsor
- Odin Medical
Polyp, Colorectal
Colorectal Polyp Clinical Decision Support Device Study
The study objective is to establish the efficacy of the colorectal polyp Clinical Decision Support Device (CDSD) in clinical use.
- Conditions
- Polyp, Colorectal, Colonoscopy
- Trial name
- CDSD (NCT04437615)
- Testing
- Colonoscopy, Clinical Decision Support Device
- Where
- United States
- Volunteers
- 2,379 people
- Sponsor
- Olympus Corporation of the Americas
Mitral Valve Regurgitation, Mitral Valve Prolapse
CE Mark Study for the Harpoon Medical Device in Poland
The purpose of this study is to evaluate the safety and performance of the Harpoon Medical TSD-5. The Harpoon device will provide many significant advantages over current surgical interventions including: 1) a small minimally…
- Conditions
- Mitral Valve Regurgitation, Mitral Valve Prolapse, Mitral Valve Insufficiency
- Trial name
- NCT02432196
- Testing
- Harpoon Medical Device
- Where
- 2 sites in Poland
- Volunteers
- 26 people
- Sponsor
- Edwards Lifesciences
Cardiac Implantable Electronic Device Infection
TYRX™ Envelope for Prevention of Infection Following Replacement With a CRT or ICD
The purpose of this study is to compare the incidence of cardiac implantable electronic device (CIED) infection and CIED mechanical complication after CIED replacement with a high-power cardiac implantable electronic device…
- Trial name
- Centurion (NCT01043705)
- Where
- 52 sites in United States
- Volunteers
- 1,262 people
- Sponsor
- TYRX, Inc.
Dry Eye Syndrome
Safety and Efficacy of an Artificial Tear for the Treatment of Dry Eye
The efficacy, safety and acceptability of a new artificial tear in subjects with dry eye will be compared to a currently-available artificial tear
- Trial name
- NCT00514852
- Testing
- Carboxymethylcellulose and Glycerin based artificial tear, Carboxymethylcellulose
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- Allergan
Melanoma, Melanoma, Skin
AI-based Medical Device Validation for Early Melanoma Detection
The goal of this observational study is to learn if a computer-aided diagnosis (CAD) system can help identify skin cancer (cutaneous melanoma).
- Trial name
- LEGIT_MC_EVCDA (NCT06221397)
- Testing
- AI-based Computer-Aided Diagnosis (CAD) Software for Skin Lesion Analysis.
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- AI Labs Group S.L