Clinical trials: Arts
HIV Infections
Tambua Mapema Plus - to Discover HIV Infection Early and Prevent Onward Transmission
This study will assess the impact of an HIV-1 RNA testing intervention targeting adult patients aged 18-39 years who seek urgent care for symptoms at primary care facilities and meet specific risk criteria for acute HIV…
- Trial name
- TMP (NCT03508908)
- Testing
- HIV-1 RNA testing
- Where
- Kenya
- Volunteers
- 2,887 people
- Sponsor
- University of Oxford
Infertility
Impact of Embryo Cryopreservation on Birth Weight
Birth weight (BW) is higher after frozen embryo transfer (FET) than after fresh embryo replacement. No study has compared the BW of siblings conceived using the same oocyte/embryo cohort.
- Trial name
- NCT03989843
- Where
- France
- Volunteers
- 183 people
- Sponsor
- University Hospital, Montpellier
HIV/AIDS and Infections
Phase II Trial of ART + Dual bNAbs vs. ART + Placebo During Primary HIV-1 Infection-impact on Post-ART Control
RHIVIERA-02 trial is a placebo-controlled double-blinded two arm prospective phase II trial. This study will test the use of broadly neutralising antibodies (bNAbs) in participants, at primary HIV infection (PHI) and ART…
- Trial name
- RHIVIERA-02 (NCT05300035)
- Testing
- Recombinant human monoclonal antibody (bNAbs)
- Where
- 17 sites in France
- Volunteers
- 69 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Infection, Human Immunodeficiency Virus
Dose-finding Study of GSK2248761 in Antiretroviral Therapy-Naive Subjects (SIGNET)
This 96 week, Phase 2b study in 150 HIV-1 infected antiretroviral (ART) naive adult subjects consists of a dose-ranging evaluation of GSK2248761 at blinded doses of 100 mg and 200 mg once daily with a control arm of open-label…
- Trial name
- SIGNET (NCT01231555)
- Testing
- GSK2248761 100 mg once daily, GSK2248761 200 mg once daily, Efavirenz 600 mg once daily
- Where
- 12 sites in France, Germany and 1 more
- Volunteers
- 23 people
- Sponsor
- ViiV Healthcare
HIV
HIV Clinic-Based Intervention to Improve ART Adherence and Prevent HIV Transmission
This research, co-sponsored by the Centers for Disease Control and Prevention and the National Institute of Mental health, is conducted at six HIV clinics in the U.S.
- Trial name
- APTcare (NCT02044484)
- Testing
- Multi-component intervention
- Where
- 6 sites in United States
- Volunteers
- 2,794 people
- Sponsor
- Centers for Disease Control and Prevention
HIV
Assessment of VAC-3S Therapeutic Properties When Combined With Standard ART in the Course of HIV-1 Infection
The purpose of this study is to evaluate the protective effect of VAC-3S in controlled HIV patients receiving standard of care antiretroviral treatment.
- Trial name
- NCT02041247
- Testing
- VAC-3S
- Where
- 12 sites in France, Germany and 1 more
- Volunteers
- 90 people
- Sponsor
- InnaVirVax
HIV Disease Progression
Acceptability, Feasibility and Effectiveness of Online Peer Support Group for ART Adherence Among Youth
In Uganda, Youth living with HIV/AIDS (YLHIVA) enrolled in HIV treatment experience suboptimal treatment adherence and have lower viral load suppression (VLS) rates compared to younger children or adults.
- Trial name
- NCT05688709
- Testing
- WhatsApp peer support group
- Where
- 3 sites in Uganda
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Infectious Diseases Research Collaboration, Uganda
Fallopian Tube Endometrioid Tumor, Fallopian Tube Mucinous Neoplasm
Physical Activity Monitored by Fitbit Charge 2 in Improving Quality of Life in Participants With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
This phase II trial studies how well physical activity monitored by Fitbit Charge 2 works in improving quality of life in participants with ovarian, primary peritoneal, or fallopian tube cancer that has come back.
- Conditions
- Fallopian Tube Endometrioid Tumor, Fallopian Tube Mucinous Neoplasm, Fallopian Tube Serous Neoplasm, Ovarian Clear Cell Tumor
- Trial name
- NCT03685695
- Testing
- Laboratory Biomarker Analysis, Monitoring Device, Physical Activity
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Roswell Park Cancer Institute
Infertility, Female, ART
Comparing Two Types of Needle for Oocytes Retrieval
In the early stages of assisted reproductive technologies (ART), oocyte retrieval was performed via laparoscopy, a cumbersome and expensive process requiring general anesthesia.
- Trial name
- NEEDLE (NCT03611907)
- Testing
- Oocyte retrieval with only aspiration system "SL1(Cook® Single Lumen)", Oocyte retrieval with aspiration and flushing system "DL1 (Cook® EchoTip® Double Lumen)"
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituto Clinico Humanitas
Breast Cancer
Assessing the Benefit of Art & Music Therapy on Quality of Life in Patients With Breast Cancer
This is a study of art-based and music-based therapy programs lasting three months (with additional follow-up 3 months after the end of the trial) in breast cancer patients currently receiving therapy as well as in cancer…
- Trial name
- NCT04493034
- Testing
- Art Therapy, Music Therapy
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Case Comprehensive Cancer Center
HIV/AIDS
Does Provision of Point of Care CD4 Technology and Early Knowledge of CD4 Levels Affect Early Initiation and Retention on Anti-retroviral Treatment (ART) in HIV Positive Pregnant Women in the Context of Option B+ for PMTCT?
The study will be conducted at 32 health care facilities in three provinces in Zimbabwe and will compare the impact of the provision Point of Care CD4 technology and early knowledge of CD4 levels on retention at 12 months, with…
- Trial name
- E4E (NCT02070900)
- Testing
- POC CD4, Programmatic Mentoring
- Where
- 32 sites in Zimbabwe
- Volunteers
- 704 people, healthy volunteers welcome
- Sponsor
- WHO, Department of Maternal, Newborn, Child and Adolescent Health
Dental Caries
Cost-efficacy Between ART and Composite Resin Restorations in Primary Molars
The aim of this randomized clinical trial study is to compare the longevity of Atraumatic Restorative Treatment (ART) using high viscosity GIC and Conventional Treatment using composite resin under rubber dam isolation and local…
- Trial name
- NCT02562456
- Testing
- ART using Fuji IX, Conventional Treatment
- Where
- Brazil
- Volunteers
- 428 people
- Sponsor
- University of Sao Paulo
ART
Importance of the Microtubule Cytoskeleton in Oocyte Competence
This study will assess if there are microtubule cytoplasmic features specifically associated with oocyte vitrification.
- Trial name
- NCT04546412
- Testing
- Vitrification and thawing
- Where
- Portugal
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Coronary Artery Disease (CAD), Stable Angina Pectoris
Identification of Lesion Characteristics in Coronary Plaques Using Multimodality Intravascular Imaging and Novel Photon-counting CT in Stable Angina
Coronary artery disease, caused by the furring up of the heart arteries by atherosclerosis, is a major cause of death in the UK.
- Conditions
- Coronary Artery Disease (CAD), Stable Angina Pectoris, Ischaemic Heart Disease (IHD)
- Trial name
- ILUMINA (NCT07864025)
- Testing
- observational study
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Queen Mary University of London
HIV Infections
Phase 1 Pilot Study of an ART Bridging Regimen in Highly Experienced Patients Unable to Achieve Viral Suppression
We hypothesize that a simple bridging ARV regimen that tends to select for virus with a low replicative capacity may tend to stabilize CD4 cell counts and HIV viral load and might be an option to consider in patients with MDR…
- Trial name
- NCT00336778
- Testing
- 3TC, TDF, NLV
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of Maryland, Baltimore
HIV-1-infection
The HIV Functional Cure Potential of UB-421 in ART Stabilized HIV-1 Patients
This is a Phase II, randomized, open-label, multi-center, active-controlled study to assess the safety, tolerability, and efficacy of UB-421 administered as an add-on to the standard ART in ART-treated HIV-1 subjects with stably…
- Trial name
- HIV-1 (NCT04404049)
- Testing
- UB-421(25 mg/kg) Q2W, UB-421(25 mg/kg) Q4W
- Volunteers
- 39 people
- Sponsor
- UBP Greater China (Shanghai) Co., Ltd
HIV Infections, Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) & Steatohepatitis (MASH)
Metabolic Liver Disease in Newly Diagnosed People Living With HIV (MASHIV-TR)
This study aims to identify the risk factors that lead to the development of metabolic liver disease in people who have been newly diagnosed with HIV.
- Conditions
- HIV Infections, Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) & Steatohepatitis (MASH), Fatty Liver
- Trial name
- MASHIV-TR (NCT07737340)
- Testing
- FibroScan (Transient Elastography), Hepatobiliary Ultrasonography (USG), Clinical and Laboratory Monitoring
- Where
- 11 sites in Turkey (Türkiye)
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Yaşar Bayındır, MD
Depression Symptoms
Measuring and Enhancing Creativity and Brain Flexibility in Adolescents With Depression
This research is designed to find out if engaging in creative activities will help adolescents with depression have more flexible thinking, start to see and appreciate their own talents, and develop a more positive view of…
- Trial name
- NCT07605975
- Testing
- Creativity Camp
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Azoospermia, Infertility
Microdissection Testicular Sperm Extraction (MicroTESE) and IVF-ICSI Outcome in Non-Obstructive Azoospermia (NOA)
We evaluated the application of surgical testicular exploration with the aid of a microscope (MictoTESE) to increase the chances of obtaining sperm in men with impaired sperm production, a condition known as non-obstructive…
- Trial name
- NCT00484081
- Testing
- Microdissection Testicular Sperm Extraction, ICSI
- Where
- Brazil
- Volunteers
- 53 people
- Sponsor
- Clinic and Research Center in Human Reproduction Roger Abdelmassih
Emotion, Impaired Cognition
Examining the Effects of (MiM) Treatment on Emotional and Cognitive Functioning of Residents in Long-term Care
To examine the effects of a music, imagery, and movement (MiM) intervention on emotional and cognitive functioning in residents living in a community-based adult long-term care facility.
- Trial name
- MiM (NCT02219620)
- Testing
- Music, Imagery, Movement, Social Control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- George Mason University
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