Clinical trials: Aspiration, Respiratory
Apnea, Sleep Apnea Syndromes
Comparison of Two Telemonitoring Auto-titrating Modalities in OSA Patients
This study compares the titration pressures achieved through two auto-titrating modalities, a new incremental fixed pressure mode versus routine auto-adjusting pressure mode, in CPAP-naïve obstructive sleep apnea patients.
- Conditions
- Apnea, Sleep Apnea Syndromes, Sleep Apnea, Obstructive, Sleep Disordered Breathing
- Trial name
- NCT03734341
- Testing
- EZ START Titration, APAP Titration
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Basque Health Service
Pleural Effusion
Diagnostic Yield of Agitated Exudative Non-infected Pleural Effusion
The goal of this study is to compare the diagnostic yield in terms of cellular content and biochemical characteristics of pre-aspiration agitated pleural fluid versus that of conventionally aspirated fluid in pleural infection…
- Trial name
- NCT05819294
- Testing
- Agitated Pleural Fluid Thoracentesis
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Alexandria University
Respiratory Function, Runners
The Effects of a Mindfulness Program on Running Performance, Respiratory Function, and Heart Rate Variability
Broadly, the objective of the research is to evaluate the effectiveness of a specific breathwork program (Les Mills Breath) on various physiological variables related to running performance, compared to a mindfulness control (20…
- Trial name
- NCT07521956
- Testing
- Mindful meditation, Breathwork
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of the Fraser Valley
Lung Tumor
The Efficacy of Shear-wave Elastography-guided Aspiration and Biopsy for Diagnosis in Lung Tumor
To use the shear-wave elastography to assist the transthoracic ultrasound-guided aspiration biopsy of peripheral lung tumor 1. To identify the intra-tumor heterogeneity of elasticity 2.
- Trial name
- NCT03881410
- Testing
- different types of ultrasound technique
- Where
- Taiwan
- Volunteers
- 413 people
- Sponsor
- National Taiwan University Hospital
Presbylarynx, Aspiration
Assessment of Laryngopharyngeal Sensation: Cancer Survivor Cohort
A previous study completed in 2022 (NCT05158179) was conducted using cohorts of healthy controls, and adults with general laryngopharyngeal disorders.
- Conditions
- Presbylarynx, Aspiration, Spasmodic Dysphonia, Globus Pharyngeus
- Trial name
- NCT06078527
- Testing
- Cheung-Bearelly Aesthesiometer, Transnasal Laryngoscopy, Questionnaires
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Physiological Adaptations, Sport Performance
Molecular Hydrogen Inhalation: Effects on Health, Exercise Capacity and Inflammatory Response - in Vivo/in Vitro Studies
Summary To comprehensively address the research aims and explore the state of knowledge of the mechanisms of biochemical response to specific tissue affecting method in form of a molecular hydrogen inhalation and will allow to…
- Conditions
- Physiological Adaptations, Sport Performance, Aerobic Capacity, Anaerobic Power
- Trial name
- NCT07130942
- Testing
- Inhalation using a molecular hydrogen generator
- Where
- Poland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Respiration, Artificial, Ventilators, Mechanical
Pivotal Evaluation of Abdominal Neuromuscular Electrical Stimulation (VentFree) for Weaning From Mechanical Ventilation
The objective of this study is to evaluate the efficacy of the VentFree Respiratory Muscle Stimulator (VentFree) in critically ill adult patients who require invasive mechanical ventilation, when compared to sham.
- Trial name
- PREVENT (NCT05759013)
- Testing
- Breath synchronized abdominal FES
- Where
- 27 sites in United States, Australia and 2 more
- Volunteers
- 250 people
- Sponsor
- Liberate Medical
Aspiration Pneumonia
Functionality and Accuracy of the smART System in Real-Life ICU Settings
Total participants in the "Functionality and Accuracy of the smART System in Real-Life ICU Settings" are 10 participants - in the current Jefferson study site there were 8 participants and in the Sheba study site (identifier…
- Trial name
- NCT03198988
- Testing
- smART Feeding Tube System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- ART Medical Ltd.
Pregnancy
Studying Fetal Breathing Patterns
Some babies have difficulty breathing, sucking, and swallowing at birth. The purpose of this study is to determine (before birth) the variables that will predict whether a newborn will experience these problems.
- Trial name
- NCT00066976
- Where
- 2 sites in United States
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pneumonia, Pneumocystis Carinii, HIV Infections
A Study of Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia
To evaluate and compare 3 anti-pneumocystis regimens plus zidovudine (AZT) in persons with advanced HIV disease and T4 cell count < 200 cells/mm3.
- Trial name
- NCT00001003
- Testing
- Pentamidine isethionate, Zidovudine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Respiratory Insufficiency, Ventilation Therapy; Complications
KAP Asynchrony Survey
The investigators developed a web-based survey to assess knowledge, attitudes and practice of health care professionals about patient-ventilator asynchrony.
- Conditions
- Respiratory Insufficiency, Ventilation Therapy; Complications, Ventilators, Mechanical, Respiration, Artificial
- Trial name
- KAPA (NCT03439683)
- Testing
- Survey about patient-ventilator asynchrony
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Drug Interactions, Anesthesia, Conduction
Interaction of Sevoflurane Propofol and Remifentanil in Anesthesia for Laparoscopic Surgery
Recently a new model for the interaction of sevoflurane propofol and remifentanil was developed. The potency of any combination of the three drugs is defined as probability that a subject tolerates laryngoscopy without movement…
- Trial name
- SPRV (NCT02457442)
- Testing
- Propofol and Remifentanil, Sevoflurane and Remifentanil, SPR 1
- Where
- Switzerland
- Volunteers
- 172 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Infant, Newborn, Hypertension, Pulmonary
Early Inhaled Nitric Oxide for Respiratory Failure in Newborns
This prospective, randomized controlled trial tested whether initiating iNO therapy earlier would reduce death and reduce the use of extracorporeal membrane oxygenation (ECMO) -- temporary lung bypass -- therapy compared with the…
- Conditions
- Infant, Newborn, Hypertension, Pulmonary, Persistent Fetal Circulation Syndrome, Pneumonia, Aspiration
- Trial name
- Early iNO (NCT00005773)
- Testing
- Inhaled Nitric Oxide, Standard iNO therapy
- Where
- 18 sites in United States
- Volunteers
- 302 people
- Sponsor
- NICHD Neonatal Research Network
Pseudomonas Infection
Cipro Inhaler for Cystic Fibrosis Children Ages 6-12
Ciprofloxacin PulmoSphere Inhalation Powder appears to be an effective and adequate antibiotic treatment for cystic fibrosis patients with P. aeruginosa colonisation.
- Trial name
- NCT00910351
- Testing
- Ciprofloxacin (Cipro, BAYQ3939)
- Where
- 4 sites in United States
- Volunteers
- 19 people
- Sponsor
- Bayer
Diabetic Peripheral Neuropathic Pain
A Study of Medical Cannabis Aerosol Via the Fixed-dose Syqe Inhaler as an Add-on Treatment of Diabetic Peripheral Neuropathic Pain (DPNP)
The primary purpose of this study is to evaluate the safety and efficacy of medical cannabis aerosol containing 0.25, 0.50, 1.0 milligrams (mg) delta (Δ) 9-tetrahydrocannabinol (THC) inhaled three times a day (TID) compared to…
- Trial name
- NCT06490445
- Testing
- Medical Cannabis
- Where
- 38 sites in Australia, Czechia and 3 more
- Volunteers
- 122 people
- Sponsor
- Syqe Medical
Weightlifting, Breathing
The Effects of Cervical and Thoracic Manipulation Therapy Applied to Weightlifting Athletes
The effects of manipulation therapy on the autonomic nervous system have been examined in the literature and while no sympathetic or parasympathetic changes were found after upper thoracic manipulation, a decrease in sympathetic…
- Conditions
- Weightlifting, Breathing, Breath Tests, Athlete
- Trial name
- NCT06606795
- Testing
- Spinal Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Aspirated Foreign Body of Lower Respiratory Tract
Thoracic Computed Tomography Scan for Diagnosis of Aspirated Foreign Bodies.
To access CT Scan as a diagnostic tool for foreign bodies aspiration.
- Trial name
- SICE (NCT00747981)
- Testing
- Thoracic CT Scan
- Where
- France
- Volunteers
- 311 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiac or Respiratory Arrest, Anaesthesia
Head Positions to Open the Airway IV
After routine induction of general anaesthesia peak airway pressure (= P max) and other respiratory parameters(i.e. expiratory tidal volume, expiratory CO2) are measured with and without head support in three different head…
- Trial name
- NCT01909310
- Testing
- head extension, neutral position, anaesthesiologist´s position
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Brain Death, Lung Transplantation
Organ Donation Survey Among Health Care Professionals in Argentina
The aim of this study is to gather information about knowledge, professional experience and attitude toward organ donation among health care professionals involved in the care of potential donors about the procurement process and…
- Conditions
- Brain Death, Lung Transplantation, Respiration, Artificial, Tissue and Organ Procurement
- Trial name
- NCT03458052
- Where
- Argentina
- Volunteers
- 200 people
- Sponsor
- Hospital Italiano de Buenos Aires
Lung Cancer
Transbronchial Catheter Aspiration and Transbronchial Needle Aspiration in the Diagnosis of Lung Cancer
The aim of this study is prospectively to determine the diagnostic sensitivity of Transbronchial Catheter Aspiration (TBCA) in comparison with Transbronchial Needle Aspiration (TBNA) in the diagnosis of peripheral nodules and…
- Trial name
- NCT00807391
- Testing
- TBCA, TBNA
- Where
- 2 sites in Germany
- Volunteers
- 48 people
- Sponsor
- Helios Klinik Ambrock