Clinical trials: Aspiration, Respiratory
Covid19
Effect of Prone Position onV/Q Matching in Non-intubated Patients With COVID-19
A prospective physiologic study, in participants with COVID-19-related pneumonia requiring supplemental oxygen (standard oxygen therapy or high-flow nasal cannula (HFNC)) less than 24 hours.
- Trial name
- NCT04754113
- Testing
- prone position
- Where
- China
- Volunteers
- 14 people
- Sponsor
- Southeast University, China
Respiration, Artificial
Use of a New Isokinetic Device for Inspiratory Muscle Training
Introduction: It is well established that physical fitness improves muscle performance either in sedentary people or in athletes.
- Trial name
- NCT02932189
- Testing
- Inspiratory muscle training
- Where
- Brazil
- Volunteers
- 102 people
- Sponsor
- Universidade Federal Fluminense
Fatigue
Fatigue and Kinematics During Isometric Activity of the Upper Limbs in Young and Older Adults
The aim of this study is to understand the relationship between perceived effort and physiological and kinematic variables caused by isometric activity of the upper limbs, as well as its relationship with socio-demographic…
- Trial name
- NCT04938791
- Testing
- Isometric activity
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Saude da Cruz Vermelha Portuguesa - Lisboa
Pulmonary Aspiration of Gastric Contents
Prophylaxis for Aspiration of Gastric Contents.
Effect of orally administered two equal and consecutive doses of proton pump inhibitors, omeprazole, lansoprazole, esomeprazole , rabeprazole and pantoprazole and Histamine 2 receptor antagonists cimetidine…
- Trial name
- NCT02703896
- Testing
- Drug either PPIS or H2RA and prokinetics, orogastric intubation
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- King Saud University
Ventilation, Airway Management
Insertion of Different Supraglottic Airway Devices on Manikin
When tracheal intubation and face mask ventilation fail, and the insertion of supraglottic airway devices (SHA) can provide ventilation, protecting the patient from hypoxemia.
- Conditions
- Ventilation, Airway Management, Education
- Trial name
- NCT05523752
- Testing
- Proseal Laryngeal Mask, Classic Laryngeal Mask, I-gel
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Ventilation
BASKA Mask Versus Endo Tracheal Tube in Gynecological Laparoscopic Surgery
The BASKA mask (Logikal Health Products PTY Ltd., Morisset, NSW, Australia) is a novel supraglottic airway device. It has many of the features of other supraglottic airways, with a number of innovations.
- Trial name
- BASKAMASK (NCT03287752)
- Testing
- BASKA MASK, Endotracheal tube
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Assiut University
Awareness, Anesthesia, Recall Phenomenon
Awareness in Old Aged Patients During Laryngoscopy and Intubation Using Isolated Forearm Technique
Awareness during general anesthesia - that has an incidence between 0.1% and 0.9% of cases and may be more in elderly - remains a concern for anesthesiologists.
- Conditions
- Awareness, Anesthesia, Recall Phenomenon, Inhalation; Gas
- Trial name
- NCT05019560
- Testing
- Sevoflurane, TIVA
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Asthma, Chronic Obstructive Pulmonary Disease
Evaluation of the Efficacy of Respicure® (Resveratrol / Quercetin) in the Management of Respiratory Conditions Including Asthma,COPD and Long COVID.
Interventional, Prospective, National, Multicentre, Randomised, Open-label, Controlled Clinical Study Comparing Two Parallel Groups, One Control Arm (Standard Treatment) Versus Intervention Arm (Standard Treatment + Study…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease, Long COVID
- Trial name
- NCT05601180
- Testing
- Respicure®, Standard of care
- Where
- 8 sites in Algeria
- Volunteers
- 402 people
- Sponsor
- Beker Laboratories
Morbid Obesity
Laryngeal Masks for Bariatric Surgery
Obese people pose specific problems as far as the management of airway during surgery. The study aims to compare efficacy and safety of two LMA devices.
- Trial name
- NCT01724970
- Testing
- ProSeal, Supreme LMA
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Padova
Respiratory Distress Syndrome, Positive-Pressure Respiration
Personalized Ventilation Based on Ventilation-perfusion Mismatch and Lung Recruitability
This observational study will explore the effects of PEEP and position on regional lung ventilation-perfusion mismatch by electrical impedance tomography (EIT) in moderate-to-severe ARDS patients with different lung…
- Conditions
- Respiratory Distress Syndrome, Positive-Pressure Respiration, Mechanical Ventilation
- Trial name
- NCT06430554
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhongda Hospital
Cardiac Arrest (CA)
PRECISION-CPR: PRecision-Controlled Ventilation in CPR
Cardiac arrest is a life-threatening emergency that requires immediate treatment with cardiopulmonary resuscitation (CPR). While chest compressions circulate blood, manual ventilation provides oxygen to the patient.
- Trial name
- NCT07088120
- Testing
- Precision-Controlled Ventilation with Real-Time Feedback, Standard Manual Ventilation During CPR
- Where
- 2 sites in United States, Mexico
- Volunteers
- 852 people
- Sponsor
- Rush University Medical Center
Peritonsillar Abscess
Ultrasound-Guided Aspiration of PTA vs Conventional Landmark Technique - a RCT
The study is a prospective randomized controlled trial conducted at two different centers at the Department of ORL - Head \& Neck Surgery, Odense University Hospital and the Department of Otorhinolaryngology, Head and Neck…
- Trial name
- NCT03824288
- Testing
- Intraoral ultrasound, The landmark technique
- Where
- 2 sites in Denmark
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Tobias Todsen
Feeding Behavior
New Chicco Bottles Study
Breastfeeding is recommended as the ideal form of nutrition for newborns and infants at least for the first 6 months of life by several Institutions such as the American Academy of Pediatrics (AAP) and the World Health…
- Trial name
- Step-Up (NCT03311282)
- Testing
- infants bottles
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Sprim Advanced Life Sciences
Mechanical Ventilation Pressure High, Bariatric Surgery Candidate
Effect of Individualized PEEP on Postoperative Pulmonary Complication in Bariatrics
Ventilation with low tidal volume and high PEEP (positive end expiratory pressure) has been shown to improve oxygenation in patients with ARDS (acute respiratory distress syndrome).
- Trial name
- NCT06168162
- Testing
- titated PEEP to best static compliance
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Respiratory Failure
Extubation With or Without Spontaneous Breathing Trial
Spontaneous breathing trial (SBT) has long been thought to be a essential process before extubation. In this study,the investigator hypothesized that SBT could be not essential during weaning from ventilator and investigated…
- Trial name
- SBT (NCT01020773)
- Testing
- spontaneous breathing trial
- Volunteers
- 67 people
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University
Infant Respiratory Distress Syndrome, Ventilator Lung; Newborn
Closed-loop Automatic Oxygen Control (CLAC-4) in Preterm Infants
Two-center, randomised controlled, cross-over clinical trial in preterm infants born at gestational age below 34+1/7 weeks receiving supplemental oxygen and respiratory support (Continous positive airway pressure (CPAP) or…
- Trial name
- CLAC-4 (NCT03163108)
- Testing
- Closed-loop automatic oxygen control (CLAC) fast in addition to RMC, Closed-loop automatic oxygen control (CLAC) slow in addition to RMC
- Where
- 2 sites in Germany
- Volunteers
- 19 people
- Sponsor
- University Hospital Tuebingen
Multiple Sclerosis
Proprioceptive Neuromuscular Facilitation in Multiple Sclerosis
Multiple Sclerosis (MS) is an autoimmune central nervous system disease characterized by inflammation, demyelination, and axonal degeneration.
- Trial name
- NCT05342025
- Testing
- PNF, Breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Biruni University
Nosocomial Pneumonia, Healthcare-Associated Pneumonia
Effect of Oral Decontamination Using Chlorhexidine or Potassium Permanganate in ICU Patients
Oropharyngeal bacteria play an important role in the pathogenesis of nosocomial pneumonia in critically ill patients. Oral cleansing with chlorhexidine has been shown to decrease incidence of pneumonia in patients undergoing open…
- Conditions
- Nosocomial Pneumonia, Healthcare-Associated Pneumonia, Aspiration Pneumonia, Ventilator-Associated Pneumonia
- Trial name
- NCT00610324
- Testing
- Chlorhexidine gluconate, Potassium permanganate
- Where
- India
- Volunteers
- 512 people
- Sponsor
- King Edward Memorial Hospital
Non-invasive Blood Pressure, Temperature
Evaluation Of The GE Monitor Product Line
This investigation is a multi-center study that will demonstrate that the GE Monitor meets equivalency and/or accuracy and/or performance criteria.
- Conditions
- Non-invasive Blood Pressure, Temperature, SpO2, Respiration
- Trial name
- NCT00730119
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- GE Healthcare
Scoliosis, Respiratory Function
The Effect of Curve Type Determined According to the Rigo Classification on Respiratory Muscle Strength, Quality of Life, and Functional Status in Individuals Diagnosed With Adolescent Idiopathic Scoliosis.
Adolescent Idiopathic Scoliosis (AIS) is a disorder that occurs between the ages of 10 and 18, with an unknown etiology, and is characterized by a three-dimensional deformity of the spine.
- Conditions
- Scoliosis, Respiratory Function, Rigo Classification, MIP
- Trial name
- NCT07863492
- Volunteers
- 120 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
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