Clinical trials: Aspiration, Respiratory
Pulmonary Embolism, Pulmonary Embolism Acute Massive
Registry of Catheter Intervention in Pulmonary Embolism
Multicenter longitudinal observational ambispective (retrospective cases from 2014 and prospective from 2018 onwards) cohort study.
- Conditions
- Pulmonary Embolism, Pulmonary Embolism Acute Massive, Pulmonary Embolism Acute, Pulmonary Embolism and Thrombosis
- Trial name
- RiTEP (NCT06348459)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital San Carlos, Madrid
Respiratory Failure, Pneumothorax
Mechanical Ventilation During Cardiac Surgery
Background There is no unanimous opinion about a lung-protective strategy in cardiac surgery. Small randomized clinical and animals trials suggest that ventilation during cardio-pulmonary bypass (CPB) could be protective on the…
- Conditions
- Respiratory Failure, Pneumothorax, Atelectasis, Aspiration Pneumonia
- Trial name
- NCT02090205
- Testing
- Non-ventilation during CPB, Ventilation with CPAP, Ventilation with 5 act/minute
- Where
- 13 sites in Italy
- Volunteers
- 780 people
- Sponsor
- Ospedale San Raffaele
Anesthesia
A Unique Device for Independent Lung Ventilation
Adequate blood oxygenation and ventilation/perfusion matching should be the main goal of anaesthetic and intensive care management.
- Trial name
- NCT02786862
- Testing
- independent ventilation
- Volunteers
- 69 people
- Sponsor
- Medical University of Lublin
Pneumonia
Effect of Pursed-Lip Breathing on Physiological Parameters and Discharge Readiness in Children With Pneumonia
This study aims to evaluate the effects of Pursed-Lip Breathing (PLB) exercises on physiological parameters (such as respiratory rate, heart rate, and oxygen saturation) and discharge readiness in children diagnosed with…
- Trial name
- PLB-PEDPNEU (NCT07106203)
- Testing
- Pursed-Lip Breathing (PLB)
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Ataturk University
Suxamethonium Sensitivity, Aspiration of Gastric Contents Into Respiratory Tract, Part Unspecified
Comparison on Succinylcholine Onset Time Assessed by Train of Four Stimulation Versus Clinical Judgment During Rapid Sequence Induction of Anesthesia
Succinylcholine is a myorelaxant agent often used during rapid sequence induction for patients who need to undergo general anesthesia but who are at risk of pulmonary aspiration of gastric content.
- Trial name
- CELOTOF (NCT03415607)
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Caen
Sarcoidosis Lung, Pulmonary Sarcoidosis
Comparative Diagnostic Yield of Endobronchial Cryo Biopsy vs Forceps Biopsy in Patients With Suspected Sarcoidosis
Sarcoidosis is a multi-systemic granulomatous disease of unknown cause that is characterized by the formation of non-caseous epithelioid cell granulomas.
- Trial name
- CREBS (NCT06853834)
- Testing
- Cryobiopsy with liquid nitrogen, Endobronchial Forceps Biopsy
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Pulmonary Nodule, Pulmonary Mass
Transbronchial Needle Aspiration in the Diagnosis of Peripheral Pulmonary Malignancy
The main purposes of this study are to assess the performance characteristics of transbronchial needle aspiration (TBNA) in the diagnosis of peripheral pulmonary lesions, and to identify the predictor variables of a positive…
- Trial name
- NCT00917137
- Testing
- TBNA + transbronchial lung biopsy + bronchial washing
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Maggiore Bellaria Hospital, Bologna
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 7 of 7)
NOTE: This is the seventh of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02919137
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Bern
Intensive Care Unit, Mortality
Analysis of the Evolution of Mortality in an Intensive Care Unit
The intensive care units is of the main components of modern healthcare systems. Formally, its aim is to offer the critically ill health care fit to their needs; ensuring that this health care is appropriate, sustainable, ethical…
- Conditions
- Intensive Care Unit, Mortality, Epidemiology, Respiration, Artificial
- Trial name
- NCT05261607
- Where
- Spain
- Volunteers
- 27,463 people
- Sponsor
- Hospital Universitario Getafe
Inhalation Injury, Pneumonitis
Prophylactic Bronchoscopy After Inhalation Injury in Burn Patients
The investigators hypothesize that the scheduled use of bronchoscopy on a regular basis after inhalation injury in burn patients will improve outcome by providing pulmonary hygiene, decrease the incidence of pneumonia, and detect…
- Conditions
- Inhalation Injury, Pneumonitis, Pneumonia
- Trial name
- NCT00997555
- Testing
- bronchoscopy
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Hurley Medical Center
Idiopathic Pulmonary Fibrosis
A Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of SM04646 Inhalation Solution in Subjects With Idiopathic Pulmonary Fibrosis (IPF)
SM04646-IPF-03 is a Phase 2a, multi-center, open-label study evaluating the safety and efficacy of a single inhaled, nebulized dose of SM04646 solution over a 12-week treatment regimen in subjects with mild to moderate IPF.
- Trial name
- NCT03591926
- Testing
- SM04646
- Where
- 6 sites in Australia, New Zealand
- Sponsor
- Biosplice Therapeutics, Inc.
Pneumonia, Aspiration Pneumonia
Community Acquired Pneumonia in Older Adults
This study will utilize diagnostic imaging and salivary biomarkers to estimate the prevalence of aspiration in older adults with suspected community-acquired bacterial pneumonia (CABP).
- Trial name
- NCT04709978
- Testing
- Videofluoroscopic Swallowing Study, Nuclear medicine pulmonary aspiration study, TOR-BSST and 3 oz Water Swallow
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Wisconsin, Madison
Dysphagia
Improving Diagnostic Standards in Dysphagia
The purpose of this research is to understand the normal function of swallowing and respiratory muscles in order to establish normal parameters.
- Trial name
- NCT04773184
- Testing
- Fiberoptic Endoscopic Evaluation of Swallowing, Videofluoroscopic Swallowing Study, Voluntary Peak Cough Flow Testing
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Florida
Pneumonia, Pneumocystis Carinii, HIV Infections
Aerosols in the Treatment of Asymptomatic Pneumocystis Pneumonia: A Pilot Study Assessing the Effectiveness of Aerosolized Pentamidine as Treatment of Subclinical Pneumocystis Infection in Patients With No Clinical Symptoms
To confirm the ability of pulmonary (lung) function testing (PFT) to detect Pneumocystis carinii pneumonia (PCP) before the development of clinical symptoms and to determine if pentamidine (PEN), a drug used in treating PCP, can…
- Trial name
- NCT00000707
- Testing
- Pentamidine isethionate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Lung Cancer
Mutation Detection of EBUS-TBNA Specimens Using NGS
The objective of the study was to compare the value of routine gene testing and next-generation sequencing (NGS) in detecting gene mutations of small specimens obtained by endobronchial ultrasound transbronchial needle aspiration…
- Trial name
- NCT02420405
- Testing
- Routine gene testing, Next-generation sequencing
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Jiayuan Sun
Virtual Reality, Intensive Care Unit Acquired Weakness
The Effects of Virtual Reality in Intensive Care Patients
Weakness of respiratory muscles delays weaning from the ventilator, prolongs hospital stay and increases treatment costs. Conventional treatments for respiratory muscles reverse these negative effects.
- Trial name
- NCT06442254
- Testing
- Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istinye University
Obstructive Sleep Apnea, Sleep Quality
Physical Activity, Sleep Quality, and Respiratory Function in Obstructive Sleep Apnea
Although exercise and physical activity have shown beneficial effects in individuals with obstructive sleep apnea (OSA), evidence regarding the effects of daily physical activity habits on sleep quality and respiratory parameters…
- Conditions
- Obstructive Sleep Apnea, Sleep Quality, Respiratory Function
- Trial name
- NCT07889154
- Testing
- Physical Activity Education
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medipol University
Pulmonary Hypertension, Pulmonary Arterial Hypertension
Acute Response of Iloprost Inhalation Using the Breelib Nebulizer in Pulmonary Arterial Hypertension
Primary objective To evaluate the effect of rapid inhalation of 2.5μgiloprost using the Breelib nebulizer on pulmonary vascular resistance (PVR) in patients with pulmonary arterial hypertension Secondary objectives To evaluate…
- Trial name
- NCT03365479
- Testing
- Iloprost
- Where
- 2 sites in Germany
- Volunteers
- 30 people
- Sponsor
- University of Giessen
COVID-19
Long-term Impact on Cardiopulmonary Function and Quality of Life in Patients Recovered From COVID-19.
FUNCTION is an observational cohort study conducted by researchers from the Instituto de Medicina Tropical Alexander von Humboldt at Universidad Peruana Cayetano Heredia and Cayetano Heredia Hospital.
- Trial name
- FUNCTION (NCT05386485)
- Testing
- None intervation
- Where
- Peru
- Volunteers
- 162 people
- Sponsor
- Universidad Peruana Cayetano Heredia
Lung Cancer
EBUS TBNA After PET/CT in Diagnosing Patients With Stage I-IIA Non-small Cell Lung Cancer Evaluated for Stereotactic Body Radiation Therapy
This clinical trial studies how well endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) after positron emission tomography/computed tomography (PET/CT) scan works in diagnosing patients with stage I-IIA…
- Trial name
- NCT02719847
- Testing
- Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- M.D. Anderson Cancer Center
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