Clinical trials: Aspiration, Respiratory
Sarcopenia
Respiratory Sarcopenia in Older Adults
The objectives of this study are to describe the prevalence of respiratory sarcopenia, evaluate its pattern of evolution over a one-year follow-up, and determine the response to a therapeutic exercise program in older adults in a…
- Trial name
- NCT06548984
- Testing
- diaphragmatic exercises, Respiratory muscle training
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Felipe León Morillas
Inadequate or Impaired Breathing Pattern or Ventilation
Supreme LMA and Proseal LMA in Prone Anesthetized Patient
There is no significant difference about success rate of two devices.
- Trial name
- SPLMA (NCT01814306)
- Testing
- Supreme LMA, Proseal LMA
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Mucociliary Clearance
Mucociliary Clearance in Healthy Subjects: Comparison of Levalbuterol and Racemic Albuterol
The purpose of this study is to determine whether lung mucociliary clearance (MCC) can be significantly enhanced in healthy subjects by one week of inhalation of nebulized levalbuterol aerosol, as compared to racemic albuterol or…
- Trial name
- NCT00325767
- Testing
- nebulized albuterol (2.5 mg/3ml/dose), nebulized levalbuterol (1.25 mg/3ml/dose)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Healthy Volunteers
Study to Compare the Pharmacodynamics and Pharmacokinetics of Acetylsalicylic Acid Powder for Oral Inhalation With Non-enteric-coated Chewable Aspirin in Healthy Adults.
The goal of this clinical trial is to compare the pharmacodynamics (PD), pharmacokinetics (PK), safety, and tolerability of acetylsalicylic acid powder for oral inhalation (i-ASA) with non-enteric-coated chewable aspirin (C-ASA)…
- Trial name
- NCT05625334
- Testing
- ASA, non-enteric-coated chewable aspirin
- Where
- 2 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Vectura, Inc.
Pulmonary Aspiration of Gastric Contents
Videolaryngoscopy Compared to Direct Laryngoscopy
Videolaryngoscope (Macintosh-type blade) compared with direct laryngoscopy for rapid sequence intubation in the operating room
- Trial name
- LARA (NCT04794764)
- Testing
- McGrath Mac, Macintosh Laryngoscope
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Johannes Gutenberg University Mainz
Thoracic, Pulmonary Restrictive Disease
Epidemiology and Prognosis of ARDS After Pulmonary Resection Surgery
The improvement in ARDS mortality over the last 20 years seems to be largely explained by the reduction of mechanical ventilation-induced injury (VILI).
- Conditions
- Thoracic, Pulmonary Restrictive Disease, ARDS
- Trial name
- ARDS_THO (NCT04818554)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Resilience, Anxiety
Music Breathing in Enhancing Resilience Among Elders at Risk of Mental Health Problems
The goal of this pilot randomised controlled trial is to examine the effects of a mindfulness-based music breathing intervention in enhancing resilience (primary outcome), and in reducing anxiety, depressive symptoms, loneliness…
- Conditions
- Resilience, Anxiety, Depressive Symptom, Loneliness
- Trial name
- NCT07631845
- Testing
- Mindfulness-based music breathing intervention, control group
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Non Small Cell Lung Cancer
The Safety and Feasibility of Costal Bone Marrow Aspiration During Thoracic Surgery
This pilot trial is designed to evaluate the feasibility and safety of obtaining bone marrow from costal aspiration during surgery.
- Trial name
- NCT05251805
- Testing
- Blood, bone marrow and lung tumor tissue collection
- Where
- Belgium
- Volunteers
- 4 people
- Sponsor
- Universitair Ziekenhuis Brussel
Acute Respiratory Distress Syndrome
Prono Position and Mechanical Power
The primary objective of the study is to compare the mechanical power applied to the respiratory system in patient with acute respiratory distress syndrome in supine positioning and after the implementation of prone positioning…
- Trial name
- PROMP (NCT04369105)
- Testing
- Prone position
- Where
- Argentina
- Volunteers
- 45 people
- Sponsor
- Sanatorio Anchorena San Martin
COVID-19 Acute Respiratory Distress Syndrome, Hypoxemia
Effects of Low Molecular Weight Heparin Therapy With Soft-Mist Inhaler for COVID-19 Induced Hypoxemia
This is an investigator initiated, single-center, open-label, Phase IIb clinical trial with 40 patients (for a total of 80 patients) to assess efficacy of Low molecular weight heparin using soft mist inhaler in the treatment of…
- Trial name
- NCT04990830
- Testing
- Inhaled Low molecular weight heparin, Standard Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University
Ventilator Weaning
Association Between P0.1 and Extubation Failure in Adult Patients With Acute Hypoxemic Respiratory Failure. A Multicenter Prospective Cohort Study
The goal of this observational study is to learn about the effect of the occlusion pressure during the first 100 miliseconds (P01) over the extubation failure in participants receiving mechanical ventilation for acute respiratory…
- Trial name
- NCT06662201
- Where
- Argentina
- Volunteers
- 256 people
- Sponsor
- Argentinian Intensive Care Society
Cardiac Arrest During and/or Resulting From A Procedure
Prehospital Laryngeal Tube vs. Bag-Valve Mask Ventilation Used by Paramedics During CPR
During CPR bag-valve mask ventilation is difficult for basically skilled rescuers. Ventilation may be inefficient or with too high pressures result in stomach inflation and aspiration.
- Trial name
- NCT01718795
- Testing
- Bag-valve mask or laryngeal tube ventilation
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Michael Baubin, MD
Critical Illness, Ventilation
Wise Choices in the Intensive Care Unit
Aim: to evaluate if the Choosing Wisely campaign can be introduced without harming critically ill patients. Background: Each year, around 45,000 patients are admitted to Sweden's 81 ICUs (intensive care units), costing 6-7…
- Conditions
- Critical Illness, Ventilation, Outcome, Dialysis
- Trial name
- WICH-ICU (NCT07013175)
- Testing
- Choosing wisely protocol
- Where
- 2 sites in Sweden
- Volunteers
- 10,000 people
- Sponsor
- Karolinska Institutet
Spinal Cord Injuries
Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury
Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with…
- Trial name
- NCT02323945
- Testing
- AIH, Walk, Strength
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Physical Therapy
Respiratory Functions, Trunk Control and Mobility Evaluation in Multiple Sclerosis
Respiratory functions and body control are affected in patients with multiple sclerosis (MS). Because of this effect, the dependency of individuals increases in daily living activities and their quality of life decreases.
- Trial name
- NCT03826095
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Apnea
A Novel Method of Non-invasive Ventilation in Children
The purpose of this study is to quantify the tidal volume generated by the pressure release immediately following the application of pressure to the chest.
- Trial name
- NCT01394172
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Alberta
ARDS, Human, Aspiration Pneumonia
Potential Biomarkers and Pathogenic Mechanism for Reflux Aspiration-induced Lung Injury.
There is limited research on aspiration pneumonia-induced ARDS (Acute Respiratory Distress Syndrome), and currently there is a lack of studies on corresponding biomarkers and pathogenic mechanisms.
- Trial name
- NCT06164639
- Testing
- aspiration, bronchial alveolar fluid, EIT V/Q test
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Shanghai Zhongshan Hospital
Asthma, Bronchial, Bronchial Asthma
Inhaled Tacrolimus, Add-on to Inhaled Corticosteroids & Long Acting B2 Agonists in Moderate to Severe Persistent Asthma
This study will evaluate the efficacy and safety of tacrolimus in patients with asthma.
- Trial name
- NCT00189722
- Testing
- Tacrolimus
- Where
- 28 sites in Czechia, Germany and 3 more
- Volunteers
- 160 people
- Sponsor
- Astellas Pharma Inc
Spinal Cord Injury
Mechanisms of Arterial Hypotension in Chronic Spinal Cord Injury
This clinical study is designed to investigate the mechanisms of blood pressure regulation and respiratory motor function affected by spinal cord injury (SCI).
- Trial name
- NCT02154412
- Testing
- Respiratory Training
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Non-invasive Blood Pressure, Temperature
Evaluation Of The GE Monitor Product Line
This investigation is a multi-center study that will demonstrate that the GE Monitor meets equivalency and/or accuracy and/or performance criteria.
- Conditions
- Non-invasive Blood Pressure, Temperature, SpO2, Respiration
- Trial name
- NCT00730119
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- GE Healthcare
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