Clinical trials: Aspiration, Respiratory
Chronic Cough (CC), Gastroesophageal Reflux (GER)
Impact of Gastroesophageal Reflux and Aspiration on Airway Inflammation and Microbiome in Children With Chronic Cough
Using an active cohort of children in whom Airway and gastrointestinal endoscopy will be performed, investigators will conduct a chart review to obtain relevant clinical data and the investigators will use an aliquot of airway…
- Trial name
- NCT02797756
- Testing
- Esophago-gastro-duodenoscopy (EGD) with biopsy, Esophageal Impedance Monitoring (EIM)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- NYU Langone Health
Bronchitis, Cough
Treatment of Respiratory Tract Infection and/or Acute Bronchitis With Ectoin Inhalation Solution
This observational, non-interventional multicentric study compares the inhalation therapy on patients suffering on respiratory tract infections and/or acute bronchitis between Ectoin inhalation solution and Pari NaCl (0.9%)…
- Conditions
- Bronchitis, Cough, Sputum, Cellular Atypia, Dyspnoea
- Trial name
- NCT02632851
- Where
- Germany
- Volunteers
- 135 people
- Sponsor
- Bitop AG
Respiratory Function Tests, Anesthesia, General
PSV on Ventilation Inhomogeneity and Lung Function in Patients Under SB Across LMA
General anesthesia has been demonstrated to have a negative impact on lung function. Both surgery and patient position influence the perioperative lung function.
- Conditions
- Respiratory Function Tests, Anesthesia, General, Patient Positioning, Ventilation
- Trial name
- VINHO (NCT02986269)
- Testing
- general anesthesia across LMA, Spontaneous breathing(SB), Pressure Support Ventilation
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Walid HABRE
Respiratory Insufficiency, Hypoxia
Effects of High Flow Nasal Cannula on Deadspace Reduction and Regional Distribution of Ventilation
1. To determine the lowest nasal cannula flow rate in which upper airway deadspace is reduced. Hypothesis - The lowest flow rate of high flow nasal cannula (HFNC) will reduce upper airway (extrathoracic) deadspace and improve…
- Trial name
- HFNC (NCT02460653)
- Testing
- HFNC Flow Rate
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Boston Children's Hospital
Head and Neck Cancer, Swallowing Disorder
İnvestigation of the Effect of Neck Endurance on Swallowing and Directional Coordination in Head and Neck Cancer Patients
In the study, it was aimed to evaluate the relationship between dysphagia, which is one of the treatment complications, and the variables of respiratory performance, intraoral pressure and neck endura, and to look at the future…
- Conditions
- Head and Neck Cancer, Swallowing Disorder, Respiratory Function, Neck Muscle Issue
- Trial name
- NCT07434245
- Testing
- Fiberoptic Endoscopic Evaluate Swallowing
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Istanbul Arel University
Respiratory Distress, Acute Lung Injury
Lung Injury Prediction Study
The purpose of the study is to externally validate the acute lung injury/acute respiratory distress syndrome (ALI/ARDS) prediction model (Lung Injury Prediction Score - LIPS) in a multicenter sample of patients at risk presented…
- Trial name
- USCTG-LIPS1 (NCT00889772)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Mayo Clinic
Foreign Body Aspiration
The Impact of Preoperative Nasal Capnography on Clinical Management in Patients Undergoing Diagnostic Bronchoscopy for Suspected Foreign Body Aspiration
Introduction Despite advances in medical care, foreign body aspiration remains a common and ongoing health concern in children. Diagnostic bronchoscopy is the gold standard for confirming the diagnosis and providing definitive…
- Trial name
- Capnography (NCT07870005)
- Testing
- Nasal capnographic examination
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Mersin University
Lung Diseases
Nasal Versus Buccal Oxygen Administration for Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration
The purpose of this study is to compare to nasal and buccal oxygen administration in patients undergoing Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration .
- Trial name
- NCT04686656
- Testing
- nasal oxygen, buccal oxygen
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya Training and Research Hospital
Respiratory Failure, Acute Respiratory Distress Syndrome
Observational Cohort Study of Distribution of Ventilation in Pediatrics Requiring Mechanical Ventilation by Electrical Impedance Tomography
Respiratory disorders are the leading cause of respiratory failure in children. Thousands of children are admitted to a pediatric intensive care unit each year and placed on mechanical ventilators.
- Conditions
- Respiratory Failure, Acute Respiratory Distress Syndrome, Acute Lung Injury
- Trial name
- EIT (NCT02247700)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Boston Children's Hospital
Pneumonia, Pneumocystis Carinii, HIV Infections
A Study of Two Forms of Pentamidine in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS
To compare parenteral versus inhaled pentamidine in patients with documented Pneumocystis carinii pneumonia (PCP) with AIDS.
- Trial name
- NCT00002292
- Testing
- Pentamidine isethionate
- Where
- United States
- Sponsor
- LyphoMed
Peritonsillar Abscess
Ultrasound-Guided Aspiration of PTA vs Conventional Landmark Technique - a RCT
The study is a prospective randomized controlled trial conducted at two different centers at the Department of ORL - Head \& Neck Surgery, Odense University Hospital and the Department of Otorhinolaryngology, Head and Neck…
- Trial name
- NCT03824288
- Testing
- Intraoral ultrasound, The landmark technique
- Where
- 2 sites in Denmark
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Tobias Todsen
Bronchiolitis
Bronchiolitis All-study, SE-Norway
Bronchiolitis is a common lower respiratory disease typically affecting infants and children generally younger than 2 years of age.
- Trial name
- NCT00817466
- Testing
- Racemic adrenaline, Isotonic saline
- Where
- 9 sites in Norway
- Volunteers
- 500 people
- Sponsor
- Oslo University Hospital
Malignant Neoplasm of Respiratory and Intrathoracic Organ Carcinoma, Lung Cancer
Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration Using a 22 vs 25-Gauge Needle
The goal of this clinical research study is to compare the effectiveness of a smaller, 25-gauge needle when used in an endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) instead of a standard 22-gauge…
- Trial name
- NCT03004586
- Testing
- 25-Gauge Needle, 22-Gauge Needle, Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA)
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- M.D. Anderson Cancer Center
Sleep Apnea Syndromes in Children, Obesity in Children
Overview: Use of Respiratory Support At Home in Children
the primary outcome is to describe the perceived success of the use of the respiratory support from the parent's point of view
- Conditions
- Sleep Apnea Syndromes in Children, Obesity in Children, Bronchopulmonary Dysplasia (BPD), Neuromuscular Disease
- Trial name
- ELIPSE (NCT06692660)
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Grenoble
Flail Chest, Ventilation
Trial of Operative Fixation of Fractured Ribs in Patients With Flail Chest
Background: Fracture of several ribs in more than one place as the result of trauma, leads to paradoxical movement of the chest wall and ventilatory failure.
- Trial name
- NCT00298259
- Testing
- operative fixation of fractured ribs
- Where
- Australia
- Volunteers
- 48 people
- Sponsor
- The Alfred
Spinal Cord Injuries
Acute Intermittent Hypoxia on Leg Function Following Spinal Cord Injury
The purpose of this study is to determine how the nervous system controlling leg muscles is altered following spinal cord injury and how they may be affected by brief periods of low oxygen inhalation over time.
- Trial name
- NCT02274116
- Testing
- AIH - Intermittent Hypoxia - hypoxia air mixture
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Spaulding Rehabilitation Hospital
Healthy
AZD5423 Multiple Ascending Dose Study
The aim of the study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD5423 following multiple ascending dose administrations in healthy male and female subjects
- Trial name
- NCT01037504
- Testing
- AZD5423
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Breast Cancer
Yoga Breathing for Fatigue in Patients Undergoing Chemotherapy
The purpose of this study is to determine the feasibility and efficacy of yoga breathing techniques to manage fatigue and other cancer-related side effects, in cancer patients undergoing chemotherapy.
- Trial name
- NCT00982748
- Testing
- Pranayama (Yoga Breathing) Techniques
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, San Francisco
Respiratory Function
Evaluation of Respiratory Function During Self-induced Cognitive Trance
The goal of this Prospective, monocentric, non-randomized, open-label study aimed at evaluating the variation of FEV1 during a state of self-induced cognitive trance participant population: Person with expertise in the practice…
- Trial name
- SPIROTRANSE (NCT06121960)
- Testing
- spirometry
- Where
- France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Metropole Savoie
Diaphragm Injury, Muscle Weakness
Electromyography for Diaphragm Effort
Mechanical ventilation may be necessary to save the life of a patient due to an accident, pneumonia or surgery. The ventilator then temporarily takes over the function of the respiratory muscles.
- Conditions
- Diaphragm Injury, Muscle Weakness, Weaning Failure, Physiological Stress
- Trial name
- Edi2Pdi (NCT03580720)
- Testing
- Inspiratory threshold loading protocol
- Where
- Netherlands
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
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