Clinical trials: Aspiration, Respiratory
Multiple Sclerosis (MS)
Avonex®: Safety, Blood Levels and Effects
The primary objective was to determine the tolerability of a new inhaled formulation of interferon beta-1a when given as a single dose, when given once per week for 4 weeks, and compared with standard intramuscular (IM) AVONEX®…
- Trial name
- C-851 (NCT01863069)
- Testing
- Interferon beta 1a, (IM) AVONEX®
- Where
- United Kingdom
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Trio Medicines Ltd.
Covid19
Effect of Prone Position onV/Q Matching in Non-intubated Patients With COVID-19
A prospective physiologic study, in participants with COVID-19-related pneumonia requiring supplemental oxygen (standard oxygen therapy or high-flow nasal cannula (HFNC)) less than 24 hours.
- Trial name
- NCT04754113
- Testing
- prone position
- Where
- China
- Volunteers
- 14 people
- Sponsor
- Southeast University, China
Asthma, Chronic Obstructive Pulmonary Disease
Evaluation of the Efficacy of Respicure® (Resveratrol / Quercetin) in the Management of Respiratory Conditions Including Asthma,COPD and Long COVID.
Interventional, Prospective, National, Multicentre, Randomised, Open-label, Controlled Clinical Study Comparing Two Parallel Groups, One Control Arm (Standard Treatment) Versus Intervention Arm (Standard Treatment + Study…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease, Long COVID
- Trial name
- NCT05601180
- Testing
- Respicure®, Standard of care
- Where
- 8 sites in Algeria
- Volunteers
- 402 people
- Sponsor
- Beker Laboratories
Respiratory Monitoring
Human Electrical-Impedance-Tomography Reconstruction Models
Current EIT analyses are based on the assumption of a circular thorax-shape and do not provide any information on lung borders. The aim is to obtain the body and lung border contours of male subjects by multi-detector computed…
- Trial name
- NCT02773680
- Testing
- "electrical impedance tomography"
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Parkinson Disease, Respiration
Telerehabilitation Based Exercise Training in Parkinson's Patients
Parkinson's disease (PD) is the second most common progressive disease after Alzheimer's disease.It is a progressive, multisystemic and neurodegenerative disease. The prevalence of Parkinson's disease increases with age.
- Conditions
- Parkinson Disease, Respiration, Gait Disorders, Neurologic
- Trial name
- NCT05621642
- Testing
- Breathing exercises, Core stabilization exercises, Balance and strengthening exercises
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Renal Function After Partial Nephrectomy
PaNeX: Partial Nephrectomy Under Xenon
Purpose of this study is to determine whether Xenon - as compared to Isoflurane - shows a nephroprotection after partial nephrectomy.
- Trial name
- PaNeX (NCT01839084)
- Testing
- Xenon, Isoflurane
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- RWTH Aachen University
Foreign Body Aspiration, Blood Gas, Bronchoscopy
Comparison of Patients With and Without Foreign Body Aspiration After Bronchoscopy.
To compare patients under 5 years of age with foreign body aspiration and without foreign body aspiration with radiological and blood gas results.
- Trial name
- NCT04467307
- Testing
- Rigit bronchoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Airway Obstruction, Asthma
Effects of Combined Respiratory Muscle Training and Steam Inhalation
The purpose of this investigation is to obtain more information on the efficacy and safety of respiratory training methods with WellO2 in patients with asthma and COPD.
- Conditions
- Airway Obstruction, Asthma, COPD
- Trial name
- NCT04584398
- Testing
- Respiratory muscle training with steam inhalation
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- WellO2 Oy
Respiratory Failure
Regional Lung Inflammation and Expansion in Mechanically Ventilated Patients - a PET/CT Study
The goal of this study is to investigate acute respiratory distress syndrome (ARDS) and septic lung with positron emission tomography (PET) imaging and to examine the distribution of inflammation, as measured by neutrophil…
- Trial name
- NCT01806532
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
COPD (Chronic Obstructive Pulmonary Disease)
Phase 1 PK Study of AERO-007, an Inhaled LABA+LAMA Combination for Nebulization Delivery in COPD Patients
This is a phase 1, single-dose, 2-period crossover study in healthy volunteers to compare the systemic pharmacokinetic (PK) profile of inhaled AERO-002 versus inhaled active comparator product.
- Trial name
- NCT07802730
- Testing
- AERO-002 (60 mcg), Glycopyrrolate (18 mcg)
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- AeroRx Therapeutics Inc.
Obstructive Sleep Apnea, Sleep Quality
Physical Activity, Sleep Quality, and Respiratory Function in Obstructive Sleep Apnea
Although exercise and physical activity have shown beneficial effects in individuals with obstructive sleep apnea (OSA), evidence regarding the effects of daily physical activity habits on sleep quality and respiratory parameters…
- Conditions
- Obstructive Sleep Apnea, Sleep Quality, Respiratory Function
- Trial name
- NCT07889154
- Testing
- Physical Activity Education
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medipol University
Pseudomonas Infection
Cipro Inhaler for Cystic Fibrosis Children Ages 6-12
Ciprofloxacin PulmoSphere Inhalation Powder appears to be an effective and adequate antibiotic treatment for cystic fibrosis patients with P. aeruginosa colonisation.
- Trial name
- NCT00910351
- Testing
- Ciprofloxacin (Cipro, BAYQ3939)
- Where
- 4 sites in United States
- Volunteers
- 19 people
- Sponsor
- Bayer
Pulmonary Disease, Chronic Obstructive
Study to Evaluate the Safety and Pharmacokinetics of Inhaled Ciprofloxacin in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Objectives of the study are to investigate the safety, tolerability and levels of ciprofloxacin in the lung after single and multiple inhalative administration to patients with moderate to severe COPD (stage II-III according to…
- Trial name
- NCT00961038
- Testing
- Ciprofloxacin (PulmoSphere, BAYQ3939)
- Where
- Germany
- Volunteers
- 19 people
- Sponsor
- Bayer
Interstitial Lung Disease
Endobronchial Ultrasound Transbronchial Needle Aspiration Of Enlarged Mediastinal In Interstitial Lung Disease
The aim of this study is to assess the findings of mediastinal/hilar LN sampling by EBUS-TBNA in patients with non-sarcoidosis interstitial lung disease ( ILD) who demonstrate LN enlargement on chest imaging.
- Trial name
- NCT04331548
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Mechanical Ventilation Complication
Assessing Gas Exchange in Intensive Care Patients on a Ventilator
In an attempt to standardise the degree of impairment of gas exchange in the lungs of ICU patients a number of indices of oxygen exchange have been developed.
- Trial name
- NCT02599350
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Aberdeen
Respiration
Optical Breath-hold Control System for Image-guided Procedures
The objective or our study is to test the feasibility of a new optical-based breath-hold control (OBC) system for monitoring breath-hold levels and providing patient feedback during CT-guided biopsies of the lung and upper…
- Trial name
- OBC (NCT01062789)
- Testing
- Optical breath-hold control system (OBC)
- Where
- United States
- Sponsor
- Mayo Clinic
Aspiration Vomitus
Granisetron Versus Metoclopramide Effects on Gastric Volume by Sonographic Assessment on Patients Undergoing Caesarean Section.
Ultrasound assessment of the effect of metoclopramide versus granisetron on gastric volume in patients undergoing caesarean section study
- Trial name
- NCT04290026
- Testing
- metoclopramide versus granisetron
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Multiple Myeloma (MM), Breathing Techniques
Effects of Controlled Breathing on Cardiorespiratory Variables in Multiple Myeloma
A randomized, parallel, double-blind, controlled, clinical trial. Two groups of participants will be included, both receiving a therapeutic exercise intervention and an educational session on the importance of proper breathing…
- Conditions
- Multiple Myeloma (MM), Breathing Techniques, Breathing Exercises, Exercise Activity
- Trial name
- NCT07376733
- Testing
- Controlled breathing exercise protocol + therapeutic exercise + initial education session, Therapeutic exercise + initial education session
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Universidad Complutense de Madrid
Community-Acquired Pneumonia
Efficacy and Safety Trial to Assess Moxifloxacin in Treating Community-Acquired Pneumonia (CAP) With Aspiration Factors
The purpose of this study is to determine whether moxifloxacin in comparison to levofloxacin plus metronidazole are effective and safe in the treatment of community-acquired pneumonia with aspiration factors.
- Trial name
- NCT00752947
- Testing
- moxifloxacin, levofloxacin, metronidazole
- Where
- 2 sites in China
- Volunteers
- 186 people
- Sponsor
- Beijing Hospital
Hyperkyphosis, Respiratory Failure
Core Stability and Respiratory Parameters in Children With Thoracic Hyperkyphosis
Hyperkyphosis, defined as an excessive curvature of the thoracic spine beyond normal limits, is among the factors that reduce chest wall mobility and lung function.
- Trial name
- NCT06853548
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Istinye University
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