Clinical trials: Aspiration, Respiratory
Spinal Cord Injuries, Brown Sequard
Effects of Breathing and Walking Treatments on Recovery Post-Spinal Cord Injury
Change to Reflect What Was Done and reason Changes Were Made. The purpose of this study is to determine (1) if a specific breathing treatment (intermittent hypoxia) can promote changes in breathing function and (2) if pairing…
- Conditions
- Spinal Cord Injuries, Brown Sequard, Central Cord Syndrome
- Trial name
- NCT01272011
- Testing
- Intermittent Hypoxia, Locomotor Training
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- VA Office of Research and Development
Pulmonary Embolism
Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
The objective of this study is to evaluate real world long-term functional outcomes, safety and performance of the Indigo Aspiration System for the treatment of pulmonary embolism (PE).
- Trial name
- NCT04798261
- Testing
- Indigo Aspiration System
- Where
- 79 sites in United States, Australia and 10 more
- Volunteers
- 1,500 people
- Sponsor
- Penumbra Inc.
Persistent Fetal Circulation Syndrome, Diaphragmatic Hernia
Antibody Secreting Cell and Cyotokine Profiles in Neonates on ECMO
Infants are placed on ECMO for correction of reversible respiratory failure. Often, because a few of the reasons for respiratory failure show us similar things in the baby, it is difficult to determine exactly which is causing…
- Conditions
- Persistent Fetal Circulation Syndrome, Diaphragmatic Hernia, Meconium Aspiration, Sepsis
- Trial name
- NCT00371241
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas Health Science Center, Houston
Critical Illness, Acute Respiratory Failure
Feasibility of Upright Bed Position in ARDS Patients
Lower lobe atelectasis of the lung is common in Acute Respiratory Distress Syndrome (ARDS) and has the potential to adversely impact lung compliance and intra-pulmonary shunt.
- Conditions
- Critical Illness, Acute Respiratory Failure, Adult Syndrome
- Trial name
- NCT02160561
- Testing
- Intervention Arm
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
COPD Grade I
Comparative Effect of Pursed Lip Breathing Alone and Combined With Alternate Nostril Breathing on Pulmonary Function Test and Quality of Life in Patients in Grade I COPD Patients.
Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory disorder characterized by airflow limitation, breathlessness, and reduced quality of life.
- Trial name
- NCT07531771
- Testing
- pursed lip breathing, Alternate Nostril breathing:
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
Spontaneous Pneumothorax
Spontaneous Pneumothorax in Children
The objective of this multi-center, non-randomized, prospective pilot study is to examine the rate of successful primary spontaneous pneumothorax (PSP) resolution using the simple aspiration technique.
- Trial name
- NCT02573285
- Testing
- Simple Aspiration, Surgeon Preference
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Intubation Intraesophageal, Respiratory Aspiration of Gastric Contents
Fibreoptic Intubation With and Without Sellick´s Maneuver
The goal of this study is to evaluate the effect of Sellick´s Maneuver, a firm pressure on the throat, just below the Adams apple, to occlude the esophagus, in order to prevent aspiration of gastric contents, on intubation with a…
- Trial name
- NCT01357824
- Testing
- Application of Sellick´s maneuver.
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Quality of Life, Behavior
Breathing and Decision-Making
The study aims to investigate how slow breathing with prolonged exhalation (i.e., ProlEx breathing) modulates decision-making under risk in healthy participants.
- Conditions
- Quality of Life, Behavior, Stress, Psychological
- Trial name
- ProlEx-MRI (NCT05936684)
- Testing
- Breathing with prolonged exhalation (ProlEx) during risky decision-making, Normal breathing (Eupnea/Control) during risky decision-making
- Where
- Germany
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- German Institute of Human Nutrition
Immunity, Cellular
Analysis of Antigen Specific B Cell Responses to Immunization With Influenza Virus Vaccine
Immunization with the inactivated influenza vaccine with blood samples collected at 7 visits (baseline, day 7, 14, 28, 60, 90 and 180, fine needle aspiration (FNAs) from axillary lymph nodes at baseline, days, 4, 14, 28, 60 and…
- Trial name
- NCT03748524
- Testing
- Influenza Vaccine
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Sedation, Respiration, Artificial
Dexmedetomidine for Postoperative Sedation in Patients Undergoing Repair of Thoracoabdominal Aortic Aneurysms
The primary objective of this study is to test the hypothesis that time on the ventilator and ICU length of stay will be shorter in TAA patients given postoperative sedation with dexmedetomidine compared to those given standard…
- Conditions
- Sedation, Respiration, Artificial, Length of Stay
- Trial name
- NCT00409344
- Testing
- Dexmedetomidine, Normal Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Lung Cancer
Endobronchial Ultrasound-transbronchial Needle Aspiration (EBUS-TBNA) Sample Division
EBUS-TBNA specimen are used for lung cancer diagnosing and staging, as well for molecular analysis. The purpose of this study is to evaluate if samples from on lymph node site can be divided for diagnosis and molecular analysis.
- Trial name
- NCT02157194
- Where
- Germany
- Volunteers
- 88 people
- Sponsor
- University Hospital, Essen
Anesthesia, Inhalation; Vapor
Decreasing Environmental Impact and Costs of Using Inhalational Anesthetic With a Carbon Dioxide Membrane Filter System
Efficient inhalational anesthetic delivery requires the use of low-flow air and oxygen to reduce drug waste and minimize workspace contamination and environmental pollution.
- Trial name
- NCT04210570
- Testing
- Memsorb, Chemical granulate absorber
- Where
- Canada
- Volunteers
- 510 people
- Sponsor
- Western University, Canada
Perinatal Morbidity
Post Term Pregnancy - Induction of Labor or Monitoring of Pregnancy
Post term pregnancy is a risk pregnancy. Aim of the study was to investigate whether induction of labor at gestational age 289(41 weeks+2 days) reduces neonatal morbidity compared to expectant management.
- Trial name
- NCT00385229
- Testing
- induction of labor
- Where
- Norway
- Volunteers
- 508 people
- Sponsor
- St. Olavs Hospital
Pulmonary Embolism, Dyspnea
Ventilation/Perfusion PET/CT With Galligas and 68Ga-MAA for Regional Lung Function Assessment After Pulmonary Embolism
In patients with pulmonary embolism (PE), after three or six months of anticoagulation, persistent dyspnea and impairment of quality of life are observed in at least 30% of cases.
- Trial name
- EOLE (NCT05103670)
- Testing
- Ventilation/Perfusion PET/CT with Galligas and 68Ga-MAA
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Brest
Apnea
A Novel Method of Non-invasive Ventilation in Children
The purpose of this study is to quantify the tidal volume generated by the pressure release immediately following the application of pressure to the chest.
- Trial name
- NCT01394172
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Alberta
Life Experiences, Respiratory Function
Validation of Study in Respiratory Physiology and it Interactions
The aim of the study was to validate tools of physiological signal processing and interpretation on healthy human volunteers in order to improve the understanding in respiratory physiology and its interactions with heart…
- Conditions
- Life Experiences, Respiratory Function, Cardiac Function
- Trial name
- ValApPhI (NCT01881945)
- Testing
- Non-invasive physiological signal recording on healthy volunteer
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Resilience, Anxiety
Music Breathing in Enhancing Resilience Among Elders at Risk of Mental Health Problems
The goal of this pilot randomised controlled trial is to examine the effects of a mindfulness-based music breathing intervention in enhancing resilience (primary outcome), and in reducing anxiety, depressive symptoms, loneliness…
- Conditions
- Resilience, Anxiety, Depressive Symptom, Loneliness
- Trial name
- NCT07631845
- Testing
- Mindfulness-based music breathing intervention, control group
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Respiratory Function
Acute and Long-Term Effects of Integrated Myofascial Release Therapy on Respiratory Function in Healthy Adults
This study will investigate the immediate and longer-term effects of integrated myofascial release therapy on breathing-related outcomes in healthy adults.
- Trial name
- EMGT-RESP (NCT07822139)
- Testing
- Other
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Multiple Sclerosis, Respiratory; Disorder, Functional, Impaired
Respiratory Function and Walking Capacity in Multiple Sclerosis
Multiple sclerosis (MS) is a chronic progressive neurological disease. Respiratory dysfunction due to weakness in the respiratory musculature has been described in MS.
- Conditions
- Multiple Sclerosis, Respiratory; Disorder, Functional, Impaired, Difficulty Walking
- Trial name
- NCT01774201
- Testing
- Breathing exercises
- Volunteers
- 50 people
- Sponsor
- Region Örebro County
Pollution; Exposure
Optimizing Ventilation to Improve Health
Our overall goal is to optimize preferred, ventilating windows/apertures/vents in low-income neighborhoods of Dhaka, Bangladesh. We will: I. Collect baseline data on housing types and finalize windows/vents protoypes. II.
- Trial name
- NCT03894995
- Testing
- Installation of ventilation
- Where
- Bangladesh
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Stanford University
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