Clinical trials: Aspiration Pneumonia
Pneumonia, Pneumocystis Carinii, HIV Infections
A Study of Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia
To evaluate and compare 3 anti-pneumocystis regimens plus zidovudine (AZT) in persons with advanced HIV disease and T4 cell count < 200 cells/mm3.
- Trial name
- NCT00001003
- Testing
- Pentamidine isethionate, Zidovudine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Rapid Sequence Induction of General Anesthesia, Sellick Maneuver
Sellick Interest in Rapid Sequence Induction
Lung aspiration can occur when a rapid sequence induction of anesthesia is performed (emergency and/or presence of at least one risk factor for regurgitation of stomach contents).
- Conditions
- Rapid Sequence Induction of General Anesthesia, Sellick Maneuver, Acid Aspiration Syndrome, Lung Aspiration
- Trial name
- IRIS (NCT02080754)
- Testing
- effective sellick maneuver
- Where
- France
- Volunteers
- 3,472 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Oropharyngeal Dysphagia, Pneumonia
Health Education to Caregivers to Reduce Aspiration Pneumonia
Randomized clinical study with a control group for assessing the decrease in the incidence of pneumonia, in a 12-month follow-up, in older people with cognitive impairment, risk of bronchial aspiration, risk of malnutrition and…
- Conditions
- Oropharyngeal Dysphagia, Pneumonia, Malnutrition
- Trial name
- HECGPN (NCT05405829)
- Testing
- Health education
- Where
- Spain
- Volunteers
- 178 people
- Sponsor
- Universitat Internacional de Catalunya
Cystic Fibrosis, Asthma
Multi Breath Nitrogen Washout (MBNW) as a Measure of Small Airway Function in Patients With Respiratory Disease
The researchers are investigating a novel technique, the multi breath nitrogen washout technique, to measure airway changes in various respiratory diseases.
- Conditions
- Cystic Fibrosis, Asthma, Bronchiolitis Obliterans, Lung Transplantation
- Trial name
- NCT00163696
- Where
- Australia
- Volunteers
- 90 people
- Sponsor
- Bayside Health
COVID-19, SARS-CoV2 Infection
Phase 1 Trial of ChAd68 and Ad5 Adenovirus COVID-19 Vaccines Delivered by Aerosol
This is a phase 1 study in healthy volunteers who have received at least three doses of an mRNA COVID-19 vaccine, to evaluate the safety and immune responses that develop in the blood and lungs following the administration by…
- Trial name
- NCT05094609
- Testing
- Ad5-triCoV/Mac, ChAd-triCoV/Mac
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- McMaster University
Inhalation Injury, Pneumonitis
Prophylactic Bronchoscopy After Inhalation Injury in Burn Patients
The investigators hypothesize that the scheduled use of bronchoscopy on a regular basis after inhalation injury in burn patients will improve outcome by providing pulmonary hygiene, decrease the incidence of pneumonia, and detect…
- Conditions
- Inhalation Injury, Pneumonitis, Pneumonia
- Trial name
- NCT00997555
- Testing
- bronchoscopy
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Hurley Medical Center
COPD, Congestive Heart Failure
Enhancing Utilization of Non-Invasive Positive Pressure Ventilation in Critical Care
Non-invasive positive pressure ventilation (NIV) refers to the provision of mechanical ventilation without an artificial airway (for example, an endotracheal tube).
- Conditions
- COPD, Congestive Heart Failure, Asthma, Respiratory Distress Syndrome, Adult
- Trial name
- NCT00458926
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Tufts Medical Center
Extracorporeal Membrane Oxygenation Complication, Neonatal Aspiration Pneumonia
Evaluating the Safety and Performance of the MiniLung Petite Kit in Neonatal and Pediatric Patients With Acute Respiratory and Cardiac Failure
This prospective observational study will evaluate the safety and performance of the MiniLung petite kit in neonatal and pediatric patients with acute respiratory and cardiac failure.
- Conditions
- Extracorporeal Membrane Oxygenation Complication, Neonatal Aspiration Pneumonia, Acute Respiratory Failure, Acute Lung Injury
- Trial name
- PETIT (NCT06750536)
- Testing
- MiniLung petite kit combined with the Xenios console
- Where
- 2 sites in Germany
- Volunteers
- 20 people
- Sponsor
- Xenios AG
Ventilation Acquired Pneumonia
The Effect of Continuous Management of Suction Cuff Pressure and Subglottic Irrigation Suction on Preventing VALRI Study
Assessing the effectiveness of continuous cuff pressure management combined with subglottic suction irrigation in reducing ventilator-associated lower respiratory tract infections (VALRTI) in mechanically ventilated patients at…
- Trial name
- SCOPE (NCT06867237)
- Testing
- Suction cuff pressure
- Volunteers
- 90 people
- Sponsor
- Shanghai Zhongshan Hospital
Acute Stroke, Aspiration Pneumonia
Metoclopramide vs Placebo for Prevention of Pneumonia in Acute Stroke
Pneumonia is a major cause of mortality and morbidity in patients with acute stroke fed via nasogastric tubes and may be because of vomiting and gastro-esophageal regurgitation.
- Trial name
- NCT04873297
- Testing
- Metoclopramide 10mg
- Where
- Pakistan
- Volunteers
- 106 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Anesthesia, Intensive Care
Pressure Course in the Tube Cuff During Swallowing
Leakage of fluid from the subglottic space to the lungs occurs along the longitudinal folds within the wall of endotracheal tube (ETT) cuffs.
- Trial name
- NCT00862797
- Testing
- pressure measurement during swallowing
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Freiburg
COVID-19
Lymph Node Aspiration to Decipher the Immune Response of Beta-variant Recombinant Protein Booster Vaccine (VidPrevtyn Beta, Sanofi) Compared to a Bivalent mRNA Vaccine (Comirnaty Original/Omicron BA.4-5, BioNTech-Pfizer) in Adults Previously Vaccinated With at Least 3 Doses of COVID-19 mRNA Vaccine.
In order to investigate whether a germinal center response occurs following vaccine boost and to characterize it based on the type of vaccine received, we aim to analyze Spike and/or RBD-specific germinal center B cells within…
- Trial name
- LymphoBOOST (NCT05951920)
- Testing
- Lymph node aspiration / Blood sampling
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris