Clinical trials: Assessment, Self
Diabetes Mellitus
FreeStyle Libre Glucose Monitoring System Paediatric Study
The study is designed to determine glycaemic control achieved using the FreeStyle Libre Flash Glucose Monitoring System (FreeStyle Libre) versus Self-Monitoring Blood Glucose (SMBG) for the self-management of diabetes.
- Trial name
- SELFY (NCT02821117)
- Testing
- FreeStyle Libre Flash Glucose Monitoring System
- Where
- 10 sites in Germany, Ireland and 1 more
- Volunteers
- 76 people
- Sponsor
- Abbott Diabetes Care
Anemia
A Study to Evaluate the Effectiveness and Safety of Epoetin Alfa During the Period When One is Donating One's Own Blood Before Surgery.
The purpose of this study is to evaluate the whether epoetin alfa stimulates the bone marrow to produce red blood cells and therefore increases a patient's ability to self-donate blood prior to major surgery.
- Trial name
- NCT00270179
- Testing
- epoetin alfa
- Volunteers
- 17 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Erectile Dysfunction
BAY38-9456, 5/10/20mg, vs.Placebo in Erectile Dysfunction
Purpose of the study is:- To assess the efficacy and tolerability of vardenafil in male subjects suffering from erectile dysfunction as compared to placebo- To assess the influence of vardenafil on the self-esteem and…
- Trial name
- NCT00665054
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 8 sites in Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Bayer
Cervical Intraepithelial Neoplasia Grade 2/3, Neoplasm Cervix
Evaluation of in Vitro Devices on Self-collected Vaginal Swab and Urine Sample for Testing of Human Papilloma Virus
The European VALHUDES study is a Clinical Performance /Diagnostic Test Accuracy Study that aims to evaluate whether HPV testing with new assays performed on self-samples, collected by means of a vaginal and a urine collection…
- Conditions
- Cervical Intraepithelial Neoplasia Grade 2/3, Neoplasm Cervix, Carcinoma in Situ, Carcinoma Cervix Uterine
- Trial name
- EU-VALHUDES (NCT04312737)
- Testing
- Self-Collecting Devices, In Vitro Diagnostic Assays
- Where
- 6 sites in Ireland, Italy and 1 more
- Volunteers
- 600 people
- Sponsor
- Hiantis Srl
Influenza, Human
Safety, Reactogenicity, and Immunogenicity Study of a Self-Amplifying MRNA Influenza Vaccine in Healthy Adults
This is a Phase 1, first-in-human, randomized, placebo-controlled, observer blind study. The effect of two doses of an investigational vaccine on safety, reactogenicity, kinetics and magnitude of the post-vaccination antibody…
- Trial name
- NCT06028347
- Testing
- sa-mRNA vaccine Dose 1, sa-mRNA vaccine Dose 2, sa-mRNA vaccine Dose 3
- Where
- 2 sites in Australia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Seqirus
Multiple Sclerosis
The Multicenter, Open-label, Single-use Autoinjector Convenience Study
The purpose of this trial is to test the Single-Use Autoinjector for a) ease of use; b) multiple domains related to subject's acceptability and satisfaction, and c) reliability of the correct function for self-injection of Rebif®…
- Trial name
- NCT00958009
- Testing
- Rebidose®
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- EMD Serono
Hair Thinning
To Evaluate the Effects of Viviscal Oral Supplements When Used by Females With Self-perceived Thinning Hair
The purpose of this multi-site, double-blind, placebo-controlled clinical study, conducted for Lifes2Good, is to evaluate certain physiological effects of Viviscal Oral Supplement compared to a placebo in female subjects with…
- Trial name
- NCT02288858
- Testing
- Viviscal Oral Supplement Tablets
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Irish Response t/a Lifes2good
Blood Self-Collection for Clinical Diagnostic Assessments
Evaluation of Tasso+ Blood Self-Collection for Clinical Diagnostic Assessment of Various Biomarkers
This study aims to assess the effectiveness and reliability of the Tasso+ capillary blood self-collection device in the clinical diagnostic assessment of various biomarkers.
- Trial name
- NCT05852925
- Testing
- Traditional Venipuncture, Tasso+
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- American Research Labs
Intracranial Aneurysm
Enterprise Stent Aneurysm Treatment (ESAT) Study - France
The purpose of this study is to evaluate the morbidity, mortality, and efficacy of use of the Enterprise(TM) stent for the treatment of (ruptured or non-ruptured) intracranial aneurysms.
- Trial name
- ESAT (NCT00879580)
- Where
- 14 sites in France
- Volunteers
- 133 people
- Sponsor
- Codman & Shurtleff
Arterial Occlusive Diseases
The Study to Treat Superficial Femoral Artery Occlusions.
The main objective of this study is to assess the performance of the Cordis SMART™ nitinol self-expandable stent for the treatment of superficial femoral artery (SFA) occlusions in comparison with balloon angioplasty only as…
- Trial name
- SUPER UK (NCT00232843)
- Testing
- stent, angioplasty
- Where
- 2 sites in United Kingdom
- Volunteers
- 150 people
- Sponsor
- Cordis US Corp.
Age-related Wet Macular Degeneration
Study to Evaluate the Safety of CG-P5 Peptide Eye Drops in Patients Diagnosed With Age-related Wet Macular Degeneration
This will be a randomized, comparative, parallel, clinical study to assess initial safety and tolerability of CG-P5 peptide eye drops compared to placebo in patients diagnosed with age-related wet macular degeneration
- Trial name
- NCT06132035
- Testing
- CG-P5 peptide, Aflibercept Injection [Eylea]
- Where
- 7 sites in United States
- Volunteers
- 45 people
- Sponsor
- Caregen Co. Ltd.
Rheumatoid Arthritis, Psoriatic Arthritis
Study to Evaluate the Ability of Subjects With Rheumatoid Arthritis or Psoriatic Arthritis to Effectively Use a Reusable Autoinjector to Self-inject Etanercept
The purpose of this study is to assess the ability of people with rheumatoid arthritis (RA) or psoriatic arthritis (PsA) to use an experimental autoinjector to self inject etanercept (Enbrel®).
- Trial name
- NCT01901185
- Testing
- Etanercept / Autoinjector A
- Where
- 13 sites in United States
- Volunteers
- 77 people
- Sponsor
- Amgen
Peripheral Arterial Disease
The ILLUMINA Study. (ILLUMINA)
The aim of the prospective, multicentre, single-arm study is to assess safety and efficacy of a drug eluting stent in Nitinol alloy (NiTiDES) in term of vessel patency and composite event-free survival rate up to two years…
- Trial name
- ILLUMINA (NCT03510676)
- Testing
- NiTiDES
- Where
- 10 sites in France, Germany and 1 more
- Volunteers
- 100 people
- Sponsor
- CID - Carbostent & Implantable Devices
Endometriosis, Uterine Fibroids
A Phase 1 Clinical Study to Evaluate the Effects of SHR7280 on the Pharmacokinetics of Midazolam, S-warfarin, Omeprazole, Digoxin, and Rosuvastatin in Healthy Subjects
The purpose of this study is to evaluate the effects of SHR7280 on the pharmacokinetics of midazolam, S-warfarin, omeprazole, digoxin and rosuvastatin in healthy subjects.
- Conditions
- Endometriosis, Uterine Fibroids, Assisted Reproduction
- Trial name
- NCT06949124
- Testing
- SHR7280 Tablets
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
COVID-19, SARS-CoV-2
Study of Self-Amplifying Messenger Ribonucleic Acid (samRNA) Vaccines Against COVID-19 in Healthy Adults and People Living With Human Immunodeficiency Virus (HIV)
The primary objective is to assess the safety and tolerability of samRNA vaccines GRT-R912, GRT-R914, and GRT-R918 when administered as prime and/or boost in healthy adult participants naïve to severe acute respiratory syndrome…
- Trial name
- NCT05435027
- Testing
- GRT-R912, samRNA-Spikebeta-TCE11, GRT-R914, samRNA-Spikebeta-TCE9, GRT-R918, samRNA-SpikeOmicron-N-TCE11
- Where
- 4 sites in South Africa
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- Gritstone bio, Inc.
Myelofibrosis
Study to Evaluate the Effect of Rabeprazole Sodium Enteric-coated Tablets on the Pharmacokinetics of TQ05105 Tablets
Primary objective: To evaluate the effect of rabeprazole on the primary pharmacokinetics of TQ05105 tablets. Secondary objective: To assess the safety and tolerability of single oral administration of TQ05105 tablets alone and in…
- Trial name
- NCT07608666
- Testing
- TQ05105 tablets, Rabeprazole sodium enteric-coated tablets
- Where
- China
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Drug Drug Interaction, Pharmacokinetic Profiles
Pharmacokinetic Effect of Y-3 for Injection on Rosuvastatin Calcium Tablets in Healthy Participants
The primary objective of this study is to evaluate the effect of Y-3 for injection on the pharmacokinetics of rosuvastatin calcium tablets (a sensitive BCRP probe substrate) in healthy participants, in order to assess the…
- Conditions
- Drug Drug Interaction, Pharmacokinetic Profiles, Safty
- Trial name
- NCT07692685
- Testing
- Use of rosuvastatin calcium tablet alone or combined with Y-3 for injection
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Neurodawn Pharmaceutical Co., Ltd.
Aortic Valve Stenosis
A Clinical Evaluation of the HYDRA Self Expanding Transcatheter Aortic Valve
The purpose of this study is the evaluation of the performance, safety and efficacy of Hydra Aortic valve in real-world patients.
- Trial name
- NCT02434263
- Testing
- Hydra TAVI
- Where
- 6 sites in Greece, Hong Kong and 4 more
- Volunteers
- 165 people
- Sponsor
- Vascular Innovations Co. Ltd.
Hearing Loss
Lyric Self-replacement Clinical Investigation
This study is designed to investigate the effectiveness and safety of the Phonak Lyric self-replacement procedure, as compared to the HCP-replacement procedure.
- Trial name
- NCT05349981
- Testing
- Phonak Lyric self-replacement procedure
- Where
- 8 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Sonova AG
Hearing Loss, Sensorineural
Self Fitting Hearing Aid Clinical Investigation
Pre-market Clinical Investigation whose primary purpose is to evaluate efficacy and effectiveness of self-fitting hearing aids
- Trial name
- NCT05612763
- Testing
- Self fitting hearing device
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Starkey Laboratories, Inc