Clinical trials: Assessment Evaluation
Human Papillomavirus (HPV) 16+ Relapsed/Refractory Cancer
Study to Evaluate the Safety and Efficacy of KITE-439 in HLA-A*02:01+ Adults With Relapsed/Refractory HPV16+ Cancers
This study has 2 parts: Phase 1A and Phase 1B. The primary objectives of Phase 1A are to evaluate the safety of KITE-439 and to determine a recommended Phase 1B dose.
- Trial name
- NCT03912831
- Testing
- KITE-439, Cyclophosphamide, Fludarabine
- Where
- 9 sites in United States
- Volunteers
- 8 people
- Sponsor
- Gilead Sciences
Healthy Subjects
A Study to Evaluate if AC-084 is Safe, Its Fate in the Body as Well as Its Potential Effects on the Body in Healthy Subjects
The primary purpose of this first-in-man study is to investigate whether AC-084 is safe and well-tolerated when orally administered at single- and multiple-ascending dose to healthy adults
- Trial name
- NCT02905253
- Testing
- AC-084
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Healthy Participants, Nutrition Intervention
Implementation and Evaluation of Nutrition Interventions
This project aims to implement and evaluate two multi-component dietary interventions focused on promoting healthy and sustainable eating behaviors and preventing weight gain among Flemish higher education students.
- Conditions
- Healthy Participants, Nutrition Intervention, Higher Education Students
- Trial name
- EATFITS (NCT06876272)
- Testing
- Healthy eating promoting programme
- Where
- 4 sites in Belgium
- Volunteers
- 653 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Type 2 Diabetes, Glucose Metabolism Disorders
The CGM-OGTT Glycemic Homeostasis Study
This is a prospective, exploratory, observational study aimed at investigating the mechanisms of glycemic homeostasis by comparing continuous glucose monitoring (CGM) data with results from the oral glucose tolerance test (OGTT).
- Trial name
- NCT07288372
- Volunteers
- 225 people
- Sponsor
- Shanghai 6th People's Hospital
COPD, Asthma
Pathogenetic Mechanisms of Chronic Obstructive Pulmonary Diseases
Asthma and chronic obstructive pulmonary disease(COPD) are common diseases, which tend to even increase in many countries. Both from a clinical and a pathophysiological point of view, this is an important issue.
- Trial name
- CAPTA (NCT01378039)
- Testing
- comparison of treatment effect on different markers
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Development and Validation of Gut Permeability Sensor, Permeability; Increased
Fluorescence Spectroscopy for Gut Permeability Assessment
This research aims to develop portable devices - known as fluorescence spectrometers - to monitor the leakage of fluorescent dyes out of the gut into the blood stream.
- Conditions
- Development and Validation of Gut Permeability Sensor, Permeability; Increased, Celiac Disease, Inflammatory Bowel Diseases
- Trial name
- GutPerm (NCT03434639)
- Testing
- Spectroscopic gut permeability test
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Overweight, Obesity
Study to Learn About How the Study Medicines Called PF-07976016 and PF-06882961 Are Taken Up by the Body, and if Either of Them Change How the Body Processes the Other Medicine in Otherwise Healthy Adults With Overweight or Obesity
The purpose of this study is to see how two study medicines, PF-07976016 and danuglipron, taken together affect the level of each other in the blood of participants who have overweight or obesity.
- Trial name
- NCT06910839
- Testing
- PF-07976016, PF-06882961
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Pfizer
Huntington Disease
Symptomatic Therapy for Patients With Huntington's Disease
Based on the previous symptomatic treatment of Chinese HD patients, this study intends to further optimize the treatment regimen of Chinese HD patients so as to further improve the prognosis of patients.
- Trial name
- NCT04071639
- Testing
- Haloperidol 2Mg Tab, Risperidone 1Mg Tab, Zoloft 50Mg Tablet
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Primary Biliary Cholangitis
Study of Saroglitazar Magnesium for PBC Patients With Incomplete Response or Intolerant to UDCA Therapy
Study of Saroglitazar Magnesium for PBC Patients with Incomplete Response or Intolerant to UDCA Therapy
- Trial name
- EPICS-IV (NCT07424677)
- Testing
- Saroglitazar Magnesium 1 mg
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Zydus Therapeutics Inc.
Bacteremia, Candidemia
Assessment of Assay for Rapid Identification of Bloodstream Infections From Whole Blood
The purpose of this study is to assess the effectiveness of RaPID/BSI by testing its performance compared to blood cultures collected prospectively from consented subjects.
- Trial name
- NCT04147975
- Testing
- RaPID/BSI Test
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- HelixBind, Inc.
Recurrent Glioblastoma
Tislelizumab (One Anti-PD-1 Antibody) Plus Low-dose Bevacizumab for Bevacizumab Refractory Recurrent Glioblastoma
The purpose of this study is to evaluate the clinical efficacy and safety of Tislelizumab (one anti-PD-1 antibody same as nivolumab approved in China) in combination with bevacizumab in patients with recurrent or progressive…
- Trial name
- NCT05540275
- Testing
- Tislelizumab plus Bevacizumab
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Henan Provincial People's Hospital
Irritable Bowel Syndrome
Investigation of Acupoint in Irritable Bowel Syndrome Based on Biological Characteristics
Irritable bowel syndrome (IBS) is a common functional disorder of the digestive system characterized by recurrent abdominal pain associated with bowel movements or changes in bowel habits.
- Trial name
- NCT06365801
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Genu Varum, Genu Valgus
IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and Dysmorphisms
While various complex pathologies of the developmental age, such as Infantile Cerebral Palsy or Neuromuscular Diseases, are notoriously considered causes of alteration of locomotor development, it is scarcely known whether…
- Conditions
- Genu Varum, Genu Valgus, Flat Feet, Cavus Foot
- Trial name
- MOTOR-CHILD (NCT05763901)
- Testing
- Clinical tests and motor control evaluation using Inertial Measurement Units
- Where
- Italy
- Volunteers
- 151 people
- Sponsor
- Istituto Ortopedico Rizzoli
Huntington Disease, Tardive Dyskinesia
A Dose-escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetic of LPM3770164 in Healthy Subjects
This is a single-center, randomized, double-blinded, placebo-controlled, dose escalation trial to evaluate the safety, tolerability and pharmacokinetic of LPM3770164 sustained-release tablets orally administered in healthy…
- Trial name
- NCT05238701
- Testing
- LPM3770164 sustained release tablet, LPM3770164 sustained release tablet simulant
- Where
- China
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Luye Pharma Group Ltd.
Staphylococcal Skin Infections
Safety and Efficacy of Daptomycin for the Treatment of Complicated Skin and Skin-structure Infections
This study will evaluate the safety and efficacy of daptomycin against complicated skin and skin-structure infections in adults
- Trial name
- NCT00463801
- Testing
- Daptomycin
- Where
- 2 sites in Italy
- Volunteers
- 52 people
- Sponsor
- Novartis
Relapsed/Refractory B-cell Malignancies
The CD19/CD20 Dual-Target in Vivo CAR-T Lentiviral Product in the Treatment of Relapsed/Refractory B-cell Malignancies
A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of the CD19/CD20 Dual-Target in vivo CAR-T Lentiviral product in the Treatment of Relapsed/Refractory B-cell Malignancies.
- Trial name
- NCT07002112
- Testing
- CD19/CD20 Dual-Target in vivo CAR-T Lentiviral product
- Where
- 6 sites in China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Fibromyalgia
Treatment and Assessment of Fibromyalgia
Fibromyalgia is a common disorder affecting approximately 2% of the Canadian population. Patients diagnosed with fibromyalgia commonly present with chronic, widespread pain as well as fatigue, depression, mood disturbances, and…
- Trial name
- NCT02760212
- Testing
- Radial Shockwave Therapy
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Lakehead University
Blood Pressure
Evaluation of the Effect of Sodium Bicarbonate Water on Blood Pressure in Normotensive Subjects
ROX_TENSIO18 is a randomised cross-over trial and the main objective is to evaluate the effect of daily consumption of sodium bicarbonate water for 15 days on blood pressure.
- Trial name
- ROX_TENSIO18 (NCT04282512)
- Testing
- Sodium bicarbonate-rich mineral water
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- My Goodlife SAS
Vitamin D Deficiency
Vitamin D Supplementation in Systemic Lupus Erythematosus
Systemic Lupus Erythematosus (SLE) is a systemic autoimmune disorder. It mainly involves the skin, the joints, the nervous system and the kidney and may be life threatening.
- Trial name
- VITALUP (NCT01413230)
- Testing
- cholecalciferol
- Where
- 3 sites in France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sickle Cell Disease, Sickle Cell Crisis
Optimal Timing of Ketamine Initiation for SCD Pain
The goal of this clinical trial is to learn if the use of early ketamine decreases the chance of admission to the hospital in patients with sickle cell disease presenting with pain.
- Trial name
- NCT07450430
- Testing
- Ketamine hydrochloride injection
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Boston Children's Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.