Clinical trials: Assessment Evaluation
Major Depressive Disorder
Sensory Synchronized Imaging and Neuromodulation
The purpose of this research study is to better understand the relationship between the type of brain stimulation used and how it changes brain activity in adult military Veterans.
- Trial name
- NCT06548113
- Testing
- TMS
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Hematologic Diseases, Bone Marrow Transplantation
Evaluation of the Impact of the Use of NewSpringForMe on Transplanted Patients' Quality of Life and Support
Bone marrow transplantation is both a great treatment for patients with hematological diseases. It is also one of the only hopes of staying alive by "starting from scratch". It is a trying life experience, at all its stages.
- Conditions
- Hematologic Diseases, Bone Marrow Transplantation, Hematopoietic Stem Cell Transplantation
- Trial name
- NSFM (NCT06148610)
- Testing
- NewSpringForMe digital solution
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Fonds de Dotation HTC Project
Healthy
Assessment of Dietary Biomarkers and Metabolic Effects After the Intake of Milk and Cheese
Dietary biomarkers are compounds in biofluids that directly reflect the intake of specific foods or food groups. Their exploration and use in the field of dietary assessments could provide an objective measure of actual intake…
- Trial name
- NCT02705560
- Testing
- Cow´s milk (3.9% fat, pasteurized), hard, yellow cheese, Soy based drink
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Degenerative Lumbar Spinal Stenosis
Evaluation of the Efficacy and Safety of the FACET FIXation Implant.
This is a single center, hybrid retrospective and prospective (ambispective) study to evaluate the safety and efficacy of the Facet Fixation implant.
- Trial name
- FACETFIX (NCT05645497)
- Testing
- Surgery with FACET FIXATION implants, Surgery with Pedicle Screw
- Where
- France
- Volunteers
- 116 people
- Sponsor
- SC Medica
Chronic Spontaneous Urticaria
Study of Efficacy and Safety of Xolair® (Omalizumab) in Chinese Patients With Chronic Spontaneous Urticaria
The purpose of this study was to demonstrate the efficacy and safety of omalizumab, compared with placebo, as an add-on to H1 antihistamines (H1AH) therapy in adult patients suffering from Chronic Spontaneous Urticaria (CSU) who…
- Trial name
- NCT03328897
- Testing
- Omalizumab
- Where
- 27 sites in China
- Volunteers
- 418 people
- Sponsor
- Novartis Pharmaceuticals
Breast, Breast Cancer
A Study of High-Dose Vit D Versus Standard of Care Vit D Supplementation
This is a randomized study evaluating the effects of early intensive vitamin D supplementation compared to standard of care vitamin D supplementation on bone health over an 18 month period.
- Conditions
- Breast, Breast Cancer, Osteoporosis
- Trial name
- NCT05016310
- Testing
- High Dose Vitamin D, Standard of Care Vitamin D
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Wake Forest University Health Sciences
Chronic Heart Failure
SYNCHRO. Evaluation of the Forecasts Parameters of Real Time-three-dimensional Doppler Echocardiography in Selecting Patients With Chronic Heart Failure for Cardiac Resynchronisation Therapy
Patients showing a normal value of SDI (< or + 8%) will randomly be assigned to CRT in "ON" or "OFF"mode at one month after implantation.
- Trial name
- NCT00488410
- Testing
- Doppler echocardiography
- Where
- France
- Sponsor
- University Hospital, Clermont-Ferrand
Rosacea, Papulopustular
Azelaic Acid Foam 15% in the Treatment of Papulopustular Rosacea
This research study is being performed to evaluate the photographic evidence of the efficacy and tolerability of Azelaic Acid Foam 15% in the treatment of papulopustular rosacea.
- Trial name
- NCT03418610
- Testing
- Azelaic Acid foam 15%
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Clinical Research Center of the Carolinas
Bipolar Disorder, Bipolar Depression
A Study To Investigate The Antidepressant Effect Of Lamotrigine In Patients With Bipolar Disorder Using Lithium
This is a study that, in the first 16 weeks, investigates whether lamotrigine versus placebo offers effect on depressive episodes for patients with bipolar disorder (also known as manic depressive disorder) who use lithium.
- Trial name
- NCT00224510
- Testing
- lamotrigine
- Where
- 31 sites in Netherlands, Spain
- Volunteers
- 120 people
- Sponsor
- GlaxoSmithKline
Tooth Diseases
Clinical Evaluation of Two Low-shrinkage Composites
Patients with 4 occlusal lesions in molar teeth will be included. Occlusal cavities will be prepared either by Er,Cr:YSGG laser (LS) or conventional diamond bur (BR).
- Trial name
- NCT03708510
- Testing
- Restorative materials- Filtek Silorane, Restorative materials-Kalore, Preparation-Er,Cr:YSGG Laser
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Hydrocephalus
Value of MRI CSF Flowmetry in Assessment of Grey Zone Hydrocephalic Patients
To evaluate accuracy of (MRI) cerebrospinal fluid flowmetry after shunt operation in patients with borderline (grey zone) hydrocephalus.
- Trial name
- NCT04060810
- Testing
- MR CSF flowmetry
- Volunteers
- 10 people
- Sponsor
- Assiut University
First in Man Study to Evaluate Initial Safety
Safety, Tolerability and Pharmacokinetics of RNV-166 in Healthy Male Volunteers
This Phase 1 first-in-human clinical study evaluated the safety, tolerability, and pharmacokinetics of RNV-166 following single ascending dose (SAD) and multiple ascending dose (MAD) administration in healthy participants.
- Trial name
- NCT07809360
- Testing
- RNV-166_200 mg
- Where
- Bangladesh
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- InVitro Research Solutions Private Limited
Advanced Hepatocellular Carcinoma
HLX07 Combination Therapy or Motherapy in Patient With Advanced Hepatocellular Carcinoma
This study is conducted in patients with advanced hepatocellular carcinoma (HCC). This study includes three arms: A, B, and C. Arm A will receive HLX07 combination therapy with HLX10 and HLX04 as first line treatment.
- Trial name
- NCT05290220
- Testing
- HLX07, HLX10, HLX04
- Volunteers
- 60 people
- Sponsor
- Shanghai Henlius Biotech
Pharmacokinetics of Isavuconazole, Healthy Volunteers
Study of the Effect of Repeat Doses of Isavuconazole on Cardiac Repolarization
This study is designed to evaluate repeat doses of isavuconazole on cardiac repolarization in healthy adult subjects. Eligible subjects will be randomized to one of four treatment groups and be confined for 17 days including…
- Trial name
- NCT01565720
- Testing
- Isavuconazole, Moxifloxacin
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Global Development, Inc.
NSCLC, SCLC
A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors
This is a Phase 1/2a, first-in-human, open-label study of JAB-8263, this study has two parts: solid tumor dose escalation and expansion study and hematology tumor dose escalation and expansion study.
- Conditions
- NSCLC, SCLC, CRPC, ESCC
- Trial name
- NCT04686682
- Testing
- JAB-8263
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Jacobio Pharmaceuticals Co., Ltd.
Periodontitis Stage II
Melatonin Loaded in Injectable Platelet-Rich Fibrin in the Management Periodontitis
melatonin loaded in injectible platelet rich fibrin in treatment of periodontitis
- Trial name
- NCT07316582
- Testing
- Melatonin-Loaded Injectable Platelet-Rich Fibrin, injectible platelet rich fibrin (i-PRF )
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Mental Disorder in Adolescence
Personalized Assessment of Client Experiences
The purpose of this study is to compare two clinical approaches to youth mental health care.
- Trial name
- PACE (NCT04369924)
- Testing
- Unidimensional Measurement-Based Care, Multidimensional Measurement-Based Care
- Where
- United States
- Volunteers
- 1,261 people
- Sponsor
- University of Miami
Hepatitis C, Chronic, Hepatitis C Virus
Effect of Insulin Resistance on the Safety and Efficacy of Pegylated Interferon and Ribavirin Treatment in HCV (Study P05562)
Naïve patients with chronic hepatitis C (CHC) of any genotype will be treated with a standard treatment regimen (pegylated interferon and ribavirin) according to routine clinical practice in Russia.
- Trial name
- NCT00705224
- Testing
- Pegylated Interferon, Ribavirin
- Volunteers
- 250 people
- Sponsor
- Merck Sharp & Dohme LLC
Cerebrospinal Fluid Drainage
Evaluation of Outcomes Related to Cerebrospinal Fluid Drain Placement
The purpose of this study is to compare the rate and severity of complications associated with CSFD placement either with or without fluoroscopic guidance.
- Trial name
- NCT04505423
- Testing
- Blind CSF Drain Placement, Fluoroscopy-guided Drain Placement
- Where
- United States
- Volunteers
- 302 people
- Sponsor
- University of North Carolina, Chapel Hill
Healthy Volunteers (HV), Muscle Activation
Assessment Of Signal Consistency Between Needle And Surface Electrodes In Tibialis Anterıor Muscle: A Pilot Validaton Study
The aim of this study is to evaluate whether surface electrodes can record physiological muscle activity as accurately as the gold-standard needle electrodes in the tibialis anterior muscle using a diagnostic EMG device The aim…
- Conditions
- Healthy Volunteers (HV), Muscle Activation, Electromyography
- Trial name
- NCT07579923
- Testing
- Needle EMG Recording, Adhesive Surface EMG Recording, Ag/AgCl Cup Electrode Recording
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Romatem Bursa Hospital
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