Clinical trials: Assessment Time
Total Knee Arthroplasty
Effection of Total Knee Arthroplasty on Knee Joint
The aim of this study is to evaluate the joint position sense of individuals diagnosed with knee osteoarthritis and who have undergone unilateral total knee arthroplasty surgery, and to examine the effect of joint position sense…
- Trial name
- NCT05965765
- Testing
- Total knee arthroplasty, osteoarthritis without surgery, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Physical Inactivity
The Relationship Between Physical Activity Level and Reaction Time in University Students
Reaction time, movement and total movement time are said to affect athletic performance. The unit of time between giving a stimulus to the person and the beginning of the person's voluntary response to this stimulus is defined as…
- Trial name
- NCT05801081
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Wounds
Oleogel-S10 in Wound Healing of Split-Thickness Skin Graft Donor Sites (BSH-12)
The main purpose of this phase III clinical trial was to compare intra-individually the efficacy, safety and tolerability of Oleogel-S10 and non-adhesive wound dressing versus non-adhesive wound dressing only in accelerating the…
- Trial name
- NCT01657305
- Testing
- Oleogel-S10, non-adhesive wound dressing, Non-adhesive wound dressing only
- Where
- 24 sites in Austria, Bulgaria and 4 more
- Volunteers
- 107 people
- Sponsor
- Birken AG
Anticoagulant Reversal, Reversal of Edoxaban Induced Anticoagulation
Effects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of Edoxaban
PER977 monotherapy and co-administration following 60 mg edoxaban will have an acceptable safety and tolerability profile with no impact on pro-coagulant biomarkers.
- Trial name
- PER977-P1 (NCT01826266)
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc.
Healthy
A Clinical Study of Enlicitide and the Effect of Food in Healthy Adult Participants (MK-0616-033)
The goal of the study is to learn what happens to enlicitide decanoate in a healthy person's body over time when taken on an empty stomach or with food.
- Trial name
- NCT06609512
- Testing
- Enlicitide
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Heart Rate, All-day Steps
Assessing the Effect of Cool Roofs on Health Using Smartwatches in Niue
Ambient air temperatures in the Pacific have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Heart Rate, All-day Steps, Distance Walked, Active Minutes
- Trial name
- REFLECT (NCT06571019)
- Testing
- Cool roof
- Where
- Niue
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Postoperative Pain
Evaluation of Postoperative Pain in Children
Postoperative pain is a common symptom of a flare up after root canal treatments (RCTs). Insufficient instrumentation, extrusion of irrigation solutions and debris and existence of a periapical lesion are the factors affecting…
- Trial name
- NCT04510571
- Testing
- Evaluating Postoperative Pain After Root Canal Treatment with Protaper Next, Evaluating Postoperative Pain After Root Canal Treatment with Reciproc Blue Files
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ege University
Hemorrhage, Trauma
Evaluation of Transthoracic Echocardiography Parameters and Their Changes in Blood Donor Volunteers
This study investigates the impact of blood donation on transthoracic echocardiography (TTE) parameters in healthy volunteers, aiming to enhance the understanding of hemodynamic changes associated with mild blood loss and assess…
- Conditions
- Hemorrhage, Trauma, Shock Hypovolemic
- Trial name
- EDoS (NCT07207629)
- Testing
- Transthoracic Echocardiography measurements
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Bipolar Depression
A First In Human Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of PF-04455242 In Single Rising Doses In Healthy Adult Volunteers
The purpose of this first in human (FIH) study is to investigate the safety, tolerability, pharmacokinetics ( how the body handles the drug) and pharmacodynamics (how the drug affects the body) of PF-04455242-01 in healthy adult…
- Trial name
- NCT00938301
- Testing
- PF-04455242
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pfizer
Respiratory Syncytial Virus Infections
A Study on the Safety and Immune Response to an mRNA-based RSV Investigational Vaccine in Healthy Adults Aged 18-45 Years
The purpose of this study is to assess the reactogenicity, safety and immune response of various formulations of the RSV mRNA investigational vaccine administered in healthy participants 18-45 years of age.
- Trial name
- NCT06573281
- Testing
- Investigational RSV vaccine 1, Investigational RSV vaccine 2, Investigational RSV vaccine 3
- Where
- 9 sites in United States, Australia and 1 more
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pulmonary Disease, Chronic Obstructive
A Randomized, Double-Blind, 4-way Crossover Study to Evaluate the Efficacy of of 24 Hour Spirometry Profiles of Inhaled BI 1744 CL and Inhaled Tiotropium Bromide in Patients With Chronic Obstructive Pulmonary Disease
The study is intended to characterize the lung function profile of BI1744 in Chronic Obstructive Pulmonary Disease (COPD) patients where patients will perform pulmonary function tests at regular intervals for 24 hours at the end…
- Trial name
- NCT01040728
- Testing
- Olodaterol (BI1744) Low, Olodaterol (BI1744) High, Tiotropium 18 mcg
- Where
- 12 sites in United States, Germany and 2 more
- Volunteers
- 122 people
- Sponsor
- Boehringer Ingelheim
Immunogenicity, Vaccine
A COHORT STUDY TO EVALUATE IMMUNOGENICITY FOR CHINESE CHILDREN AT THE TIME OF CLINICAL PNEUMONIA DIAGNOSIS
This is a PAC study after PCV13 launch in China. Based on recommendation from China Agency, Pfizer was required to conduct a descriptive immunogenicity study to measure the antibody levels at the time of disease onset.
- Trial name
- NCT05372575
- Testing
- PCV13 PAC study
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Pfizer
Impacted Tooth With Abnormal Positioning
Evaluation of the Accelerated Traction of Impacted Canines in Terms of Speed and Changes in the Dental Arches
The time required for orthodontic traction of impacted canines after surgical exposure is a particularly troubling clinical problem because it prolongs the orthodontic treatment duration.
- Trial name
- NCT05891665
- Testing
- Corticotomy, Traditional traction of the impacted canine without corticotomy
- Where
- Syria
- Volunteers
- 46 people
- Sponsor
- Damascus University
Alzheimer Disease, Gastric Retention
Study to Evaluate Safety/Duration in Stomach of Extended Release Capsules Containing Memantine Hydrochloride in Healthy Adults
To assess how long memantine hydrochloride (HCl) (50 mg) extended release capsules stay in the stomach as determined by imaging assessment (MRI or abdominal ultrasound).
- Conditions
- Alzheimer Disease, Gastric Retention, Healthy
- Trial name
- NCT03711825
- Testing
- LYN-057, Imaging Assessment (MRI), Imaging Assessment (U/S)
- Where
- Australia
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Lyndra Inc.
Smoking Cessation
Study to Evaluate Effect of Food on Bioavailability of Single 3 mg Tablet and Pharmacokinetics (PK) of Multiple 3 mg Doses in Healthy Adult Smokers
To assess the effect of food on the bioavailability of 3 mg cytisinicline following single-dose administration, and to evaluate the PK profile of 3 mg cytisinicline TID following multiple days of administration during Days 5-8.
- Trial name
- NCT05981768
- Testing
- Cytisinicline
- Where
- Portugal
- Volunteers
- 30 people
- Sponsor
- Achieve Life Sciences
Healthy Participants
A Study of Safety of SUN-0864 and How it is Processed by and Affects the Body in Healthy Adults and Healthy Adults Who Are Overweight or Obese.
This Phase 1, first-in-human study will evaluate the safety and tolerability of SUN-0864, how the body processes SUN-0864, and how SUN-0864 affects the body in healthy adults and otherwise healthy adults who are overweight or…
- Trial name
- NCT07905560
- Testing
- SUN-0864 (Formulation 1) or SUN-0864 (Formulation 2)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Superluminal Medicines, Inc.
Parkinsonism, Tremor
TRANSPARK_LONG: The Diagnostic Value of Early Transcranial Ultrasound in Patients With Extrapyramidal Diseases in a Swedish Population
Popular science summary of the project The purpose of the study is to investigate in a Swedish population how well the investigators' previous ultrasound findings match the final diagnosis (PD, APS or ET) after a particularly…
- Conditions
- Parkinsonism, Tremor, Dementia
- Trial name
- NCT06032585
- Where
- Sweden
- Volunteers
- 74 people
- Sponsor
- Region Skane
the Influence of Intra- vs Extra-abdominal Removal of Placenta, Duration of Operation
Extra-abdominal Removal of Placenta During CS
During cesarean section, it is important to provide hemostasis as well as to decrease the amount of hemorrhagic fluid and fibrin in the abdominal cavity.
- Conditions
- the Influence of Intra- vs Extra-abdominal Removal of Placenta, Duration of Operation, the Amount of Aspirated Fluid During the Operation, Difference Between Pre- and Post-operative CBC
- Trial name
- NCT02101450
- Testing
- Extra-abdominal removal of the placenta
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Atrial Fibrillation
Lesion Contiguity in Very High Power-short Duration Ablation
This observational trial investigates the effect of very high power-short duration radiofrequency ablation on lesion contiguity as assessed by late gadolinium enhancement cardiovascular magnetic resonance (LGE-CMR).
- Trial name
- NCT05368610
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- University of Barcelona
Obesity
Weight Loss In Obese Subjects Taking Either GW869682 Or Placebo 3 Times Per Day For 12 Weeks
GW869682 causes glucose to be excreted in the urine. The purpose of this study is to see whether enough calories from glucose are excreted in the urine to cause weight loss.
- Trial name
- NCT00297180
- Testing
- GW869682
- Where
- 3 sites in United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
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