Clinical trials: Assessment Time
Pulpectomy
Evaluation of Instrumentation Time and Obturation Quality Using Two Different Pediatric Rotary File Systems in Primary Molar Pulpectomy
Preserving primary teeth is essential for maintaining normal chewing, speech development, and psychological well-being. Successful pulpectomy depends on effective chemomechanical preparation of the root canals while preserving…
- Trial name
- NCT07672990
- Testing
- Pediatric NiTi rotary files manufactured with AF-H Wire technology, Pediatric NiTi rotary files manufactured with blue wire technology
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Congenital Heart Disease
Extubation Times in Postoperative Congenital Cardiovascular Surgeries
Background: Anesthesia management in pediatric cardiac surgeries focuses on reducing morbidity and mortality, early mobilization and discharge, using health resources sparingly and increasing the quality of life of patients.
- Trial name
- NCT05332860
- Testing
- Congenital Cardiovascular Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Exercise, Aging
Enhancing Physical Activity and Healthy Aging Among Recent Retirees
The purpose of REACT project is to provide cost-effective way to promote physical activity and reduce sedentary time among older adults.
- Conditions
- Exercise, Aging, Retirement
- Trial name
- REACT (NCT03320746)
- Testing
- Polar Loop 2 activity tracker
- Where
- Finland
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- University of Turku
Obesity
Quality of Life Outcomes and Economic Impacts of Bariatric Surgery
The purpose is to determine the economic, clinical and quality of life outcomes of bariatric surgery and describe the consequences of protracted wait-times (~ 2 years) for this procedure.
- Trial name
- NCT00850356
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- University of Alberta
Sedentary Lifestyle
The Impact of Real-time Feedback on Physical Activity Patterns in Flemish Employees
The aim of the study is to assess an increase of daily physical activity from electronic self-monitoring, to compare these values to the 10.000 step program, and to compare with real-time feedback with and without guidance from a…
- Trial name
- NCT01432327
- Testing
- SenseWear display, Pedometer, SenseWear Armband
- Where
- Belgium
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Plaque Psoriasis
NB-UVB Phototherapy With and Without Topical LCD Treatment: a Bilateral Pilot Study
The purpose of this study is to determine if combining a daily at-home regimen using an LCD Solution with a 3 times weekly outpatient narrowband UVB phototherapy regimen could be a safe, effective, rapid, and, convenient…
- Trial name
- NCT00708851
- Testing
- LCD Solution with NB-UVB Phototherapy, NB-UVB Light Device (311-315 nm)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- NeoStrata Company, Inc.
Sleep Quality, Compliance
Changes in 24-hour Activity Cycle Behaviors During a Time-Restricted Eating Intervention in College-Aged Women
Time-restricted Eating (TRE) is a dietary approach that limits food intake to 4 - 12-hour windows without intentionally altering diet quality.
- Conditions
- Sleep Quality, Compliance, Physical Activity, Sedentary Behaviors
- Trial name
- DAWG-TREAT (NCT07520786)
- Testing
- Time Restricted Eating, Control
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Multiple Sclerosis
GSK2018682 FTIH in Healthy Volunteers
This protocol describes the first administration of GSK2018682 to humans. The study will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of single ascending doses of GSK2018682.
- Trial name
- P1A114070 (NCT01387217)
- Testing
- GSK2018682
- Where
- 2 sites in Australia
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Carotid Artery Stenosis
Time to Post-Anesthesia Neurological Evaluation With Three Different Anesthetic Techniques
The objective of this pilot study is to analyze the differences in time to first postoperative neurological examination (cranial nerve XII - tongue movement, movement of extremities) and intraoperative hemodynamic stability with…
- Trial name
- NCT03996148
- Testing
- Remifentanil, Propofol, and Desflurane, Remifentanil, Dexmedetomidine, and Desflurane, Remifentanil and Desflurane
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The Cooper Health System
Nonhematologic Malignancies, Lymphoma
Pharmacokinetics Study of Oral IXAZOMIB in Participants With Advanced Nonhematologic Malignancies or Lymphoma
This is an open-label, multicenter, sequential, 5-arm, phase 1 study of oral IXAZOMIB designed to assess drug-drug interaction with ketoconazole (Arm 1), the relative bioavailability of 2 capsule formulations of IXAZOMIB (Arm 2)…
- Trial name
- NCT01454076
- Testing
- Ixazomib 2.5 mg, Ixazomib 4 mg Capsule A, Ixazomib 4 mg Capsule B
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Millennium Pharmaceuticals, Inc.
Diabetes Mellitus
A Clinical Study of the C8 MediSensors Optical Glucose Monitor™
The purpose of this study is to compare glucose measurements from the C8 MediSensors non-invasive Optical Glucose Monitor™ System to blood glucose measurements from the Yellow Springs Instrument(YSI) blood glucose analyzer.
- Trial name
- Spectrum (NCT01726114)
- Testing
- Non-invasive Optical Glucose Monitor™, YSI blood glucose analyzer
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- C8 MediSensors, Inc.
Diabetes Mellitus, Type II
´Sit Less, Move More' at Work: mHealth Intervention on Office Employees With Diabetes Type 2.
The objective of the study is measuring the impact of a ´sit less, move more' mHealth intervention at work on the glycaemic control and anthropometric profile of office employees with diabetes type 2 (DT2) at short, mid and long…
- Trial name
- Walk@Work (NCT04092738)
- Testing
- Walk@WorkApp-Diab
- Where
- Spain
- Volunteers
- 368 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Malocclusion
Evaluation of the Perceived Experience of Patients Treated With Aligners With Two Different Timings
The primary aim of the study is to compare the perception of pain and discomfort with two different protocols of attachments' placement during clear aligner therapy: the conventional protocol (CP), when attachments' placement is…
- Trial name
- ALLIN-1 (NCT06536335)
- Testing
- Biomax Nuvola aligners
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
covid19
Efficacy and Safety of Nitazoxanide for Post Exposure Prophylaxis of COVID-19
The primary objective of this study is to evaluate the efficacy of the drug nitazoxanide 600 mg, administered three times a day, in relation to placebo in preventing the development of COVID-19 in subjects from vulnerable…
- Trial name
- NCT04435314
- Testing
- Nitazoxanide
- Volunteers
- healthy volunteers welcome
- Sponsor
- Azidus Brasil
Sepsis, Bacteremia
Evaluation in the Treatment of Nosocomial Sepsis Comparing Polymerase Chain Reaction With Conventional Blood Culture.
The objective of this study is to evaluate the consumption of antimicrobial therapy in patients comparing a rapid molecular test (PCR in Real-Time Multiplex) with blood cultures to identify the etiological agents of sepsis.
- Conditions
- Sepsis, Bacteremia, Fungemia
- Trial name
- NCT01450358
- Testing
- Antibiotic regimen
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Instituto do Coracao
Pancreatic Cancer Resectable
Investigation of the Optimal Duration of Neoadjuvant Therapy for Resectable Pancreatic Cancer
Investigating the Optimal Duration of Neoadjuvant Chemotherapy for Resectable Pancreatic Cancer to Determine the True Surgical Indication.
- Trial name
- NCT06809374
- Testing
- gemcitabine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kochi University
GERD
Heartburn, Gastroesophageal Reflux Disease
Gastroesophageal reflux disease (GERD) is a condition caused by the reflux of stomach contents into the esophagus, presenting with typical symptoms such as heartburn and acid regurgitation.
- Trial name
- GERD (NCT07268820)
- Testing
- Zastaprazan, Esomeprazole
- Where
- 10 sites in South Korea
- Volunteers
- 160 people
- Sponsor
- Incheon St.Mary's Hospital
Euploid Embryos
Embryo Aneuploidies and Morphokinetics in Ovarian Stimulated and Non Stimulated IVF Cycles
The purpose of this study is to compare the number of euploid embryos obtained per metaphase II oocyte in unstimulated (modified natural cycles) and stimulated IVF cycles.
- Trial name
- AMOS (NCT03128580)
- Where
- 3 sites in Spain
- Volunteers
- 40 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Non-small Cell Lung Cancer
A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)
This is a multi-site, open-label, dose-finding study, consisting of Parts 1, 2a, and 2b to investigate the combination of BNT326 with pumitamig (also known as BNT327 or PM8002) in participants with relapsed, progressive as well…
- Trial name
- NCT07111520
- Testing
- BNT326, Pumitamig
- Where
- 86 sites in United States, Australia and 8 more
- Volunteers
- 880 people
- Sponsor
- BioNTech SE
The Aim of Our Study Was to Evaluate the Outcomes in Women Who Implemented the Enhanced Recovery After Surgery Protocol at Delivery by Cesarean Delivery
Implementation of Enhanced Recovery in Women Undergoing Cesarean Delivery
Aim: The aim of our study was to evaluate the outcomes in women who implemented the ERAS (Enhanced Recovery after Surgery) protocol at delivery by cesarean delivery(CD).
- Trial name
- ERAS (NCT05841888)
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ali Yavuzcan
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