Clinical trials: Assessment Time
Bacterial Vaginosis (BV)
An Open Single-armed Investigation to Evaluate the Safety of pHyph Following a Prolonged Treatment Duration in Adult Women With Bacterial Vaginosis
1. Rationale Bacterial vaginosis (BV) is caused by an overgrowth of bacteria and affects most women at some point. The infections can cause foul-smelling discharge and sometimes itching and burning.
- Trial name
- NCT07394777
- Testing
- pHyph
- Where
- 2 sites in Sweden
- Volunteers
- 32 people
- Sponsor
- Gedea Biotech AB
Sore Throat, Pharyngitis
APC-111 MP Tablet Once a Day vs.Penicillin VK Four Times a Day Both for 10 Days in Patients With Strep Throat
The primary objective of this study is to evaluate the efficacy of APC 111 MP Tablet, 775 mg tablet, given orally (PO)once daily (QD) for 10 days compared to that of Penicillin VK, 250 mg PO four times daily (QID) for 10 days in…
- Conditions
- Sore Throat, Pharyngitis, Tonsillitis
- Trial name
- NCT00242281
- Testing
- APC-111 MP Tablet, 775 mg
- Where
- 41 sites in United States, Canada
- Volunteers
- 600 people
- Sponsor
- Advancis Pharmaceutical Corporation
Infections, Soft Tissue
Safety, Immunogenicity and Efficacy of GSK S. Aureus Candidate Vaccine (GSK3878858A) When Administered to Healthy Adults (Dose-escalation) and to Adults 18 to 64 Years of Age With a Recent S. Aureus Skin and Soft Tissue Infection (SSTI)
The study evaluates the safety, immunogenicity, and efficacy of the GSK S. aureus candidate vaccine (GSK3878858A) when administered to two groups: healthy adults (dose-escalation phase) and adults aged 18 to 64 years with a…
- Trial name
- NCT04420221
- Testing
- Sa-5Ag half dose non-adjuvanted, Sa-5Ag full dose non-adjuvanted, Sa-5Ag half dose adjuvanted
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Recovery, Recovery Time
Effect of Blood Flow Restriction on Recovery After Maximal Resistance Exercise
Resistance training has been widely performed due to its health benefits. However, performing this training at high intensity causes significant muscle stress, leading to fatigue and compromising performance.
- Trial name
- NCT07342634
- Testing
- BFR-80%, BFR-60%, BFR-10mmHg
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Paulista University
Spinal Anesthesia, Ultrasound
Comparison of the Efficacy of Conventional Landmark, Ultrasound-Assisted, and Real-Time Ultrasound-Guided Techniques in Spinal Anesthesia for Obese Patients
Spinal anesthesia is frequently administered using the conventional landmark technique. Ultrasound is a non-invasive and safe approach.
- Trial name
- NCT06191445
- Testing
- Conventional Landmark Technique, Ultrasound Assisted Technique, Real-Time Ultrasound Guided Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Uludag University
Sepsis
Dexmedetomidine for Sepsis in ICU Randomized Evaluation Trial
Background: Dexmedetomidine, a highly selective arfa2-adrenergic agonist, is known to be a unique sedative agent which causes less acute tolerance, drug addiction and withdrawal compared with gamma-aminobutyrate (GABA) agonists.
- Trial name
- DESIRE (NCT01760967)
- Testing
- Dexmedetomidine
- Where
- Japan
- Volunteers
- 203 people
- Sponsor
- Wakayama Medical University
Sedentary Lifestyle, Metabolic Disturbance
Sedentary Behavior and Health Outcomes Study
This study is a randomized crossover trial to compare the effectiveness of interrupting SB on glucose homeostasis in the lab and free-living settings.
- Conditions
- Sedentary Lifestyle, Metabolic Disturbance, Pediatric Obesity, Physical Activity
- Trial name
- SBHO (NCT03153930)
- Testing
- Walking breaks, Sitting only
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Southern California
CLL (Chronic Lymphocytic Leukemia)
A Trial to Evaluate the Efficacy and Safety of a Fitness-adapted Thera-py Approach With Either Continuous Zanubrutinib Monotherapy or Time-limited Zanubrutinib + Sonrotoclax in Older and/or Frail Patients With Treatment-naïve CLL
The CLL-Frail2 trial will be a prospective, open-label, multicentre phase-II-trial to evaluate the efficacy and safety of a fitness-adapted therapy approach with either con-tinuous zanubrutinib (BGB-3111) monotherapy or…
- Trial name
- NCT07899398
- Testing
- Zanubrutinib, Sonrotoclax
- Volunteers
- 80 people
- Sponsor
- German CLL Study Group
Wounds
Clinical Validation of a 'Hand-held' Fluorescence Digital Imaging Device for Wound Care Applications
The primary objective of this clinical study is to evaluate the use and effectiveness of our 'handheld' fluorescence digital imaging device platform for real-time non-invasive clinical monitoring of chronic wounds for healing and…
- Trial name
- NCT01378728
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- University Health Network, Toronto
Healthy Adult, Healthy Adolescents
Evaluation of IXCHIQ® Vaccine Immunogenicity
The goal of this clinical trial is to evaluate the quality and duration of the immune response against chikungunya virus elicited by the IXCHIQ® vaccine in healthy adults and adolescents.
- Trial name
- IMUNO-CHIQ (NCT07846293)
- Testing
- IXCHIQ vaccine
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Mauro Martins Teixeira
Non Small-cell Lung Cancer
Trial Involving Subjects Over 70 Years of Age With Non Small-cell Lung Cancer of Stage IV and Comparing a "Classical" Strategy of Treatment Allocation, With an"Optimized" Strategy Allocating the Same Treatments
This is a phase III randomized multicenter study involving subjects over 70 years of age with non small-cell lung cancer of IV and a PS of 0, 1 or 2, who have not previously received chemotherapy.
- Trial name
- ESOGIA (NCT01257139)
- Testing
- Dual-agent therapy or docetaxel alone or best supportive care
- Where
- 45 sites in France
- Volunteers
- 490 people
- Sponsor
- Rennes University Hospital
Cataract Surgery, Patient Satisfaction
Evaluation of Duration of Anesthesia and Patient Satisfaction After Retrobulbar Block Applied in Cataract Surgery
It is aimed to determine patient satisfaction (pain assessment during and after the operation) and the initial and total anesthesia durations of eye lid and globe anesthesia after administration of local anesthetic solution only…
- Conditions
- Cataract Surgery, Patient Satisfaction, Akinesia, Anesthesia, Local
- Trial name
- NCT04178200
- Testing
- Lidocaine 2% Injectable Solution 0.75 ml, Bupivacaine Hcl 0.5% Inj 0.75 ml, Lidocaine 2% Injectable Solution 1.5 ml
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Develi Devlet Hastanesi
Diffuse Systemic Sclerosis
Serial Night Time Position Splint on Systemic Sclerosis
This is a randomized controlled trial with blinded evaluator and follow-up of one year. Seventy six patients with diffuse systemic sclerosis, will be randomized into two groups.The patients can not change their medication during…
- Trial name
- NCT01586663
- Testing
- Serial night time position splint, Drug treatment
- Where
- Brazil
- Volunteers
- 76 people
- Sponsor
- Federal University of São Paulo
Cerebral Palsy, Spina Bifida
The Effectiveness of Participation-focused Interventions on Body Functions of Youth With Physical Disabilities
Youth with physical disabilities face greater restrictions to participation in community-based activities than their typically developing peers, which can lead to poor health outcomes.
- Conditions
- Cerebral Palsy, Spina Bifida, Muscular Dystrophies, Musculoskeletal Disorder
- Trial name
- NCT03851107
- Testing
- Engagement in 6-week community-based activity program
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- McGill University
Rapid Sequence Intubation
Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements
This study examines the performance of a nasal cannula end-tidal oxygen (EtO2) measurement as compared to the gold standard of single breath end-tidal oxygen measurements in healthy volunteers.
- Trial name
- NCT03840486
- Testing
- Non-rebreather mask (NRBM), Non-invasive ventilator mask (NIV), Nasal cannula EtO2 sensor
- Where
- 2 sites in United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Emory University
Lung Cancer
Comparison of Emergence and Oxygenation During One-lung Ventilation With Desflurane and Propofol Anesthesia
Which is more adequate general anesthetic agent, desflurane or propofol, for emergence and recovery time, and perioperative oxygenation in lung resection surgery?
- Trial name
- NCT02324283
- Testing
- desflurane, propofol
- Where
- Japan
- Volunteers
- 80 people
- Sponsor
- Juntendo University
Poor Performance Status
Innovative Training Methods for Frail Elderly in the Training Gain Stage
This study aims to examine long term effects in the training gain stage of the falls management exercise programs (FaME, from Skelton and Dinan) over 10 weeks on physical functional performance after mechanical SR-WBV, dance…
- Trial name
- NCT01713790
- Testing
- Stochastic resonance whole-body vibration, Exergame, Leg press
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Athletic Injuries
FITLIGHT Reliability and Acute Training Effects
The purpose of this study is to assess the reliability of outcomes collected using a speed and cognitive light training system. This study will also be used to understand the effects of brain training on athletic performance…
- Trial name
- NCT06748417
- Testing
- Acute Cognitive Training, Non-stimulating Rest
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Miami
Locally Advanced or Metastatic Medullary Thyroid Cancer, Medullary Thyroid Cancer
Study to Determine if Contacting Patients With MTC More Frequently Results in Earlier Detection and Treatment of Signs and Symptoms of AEs and Thus a Decrease in the Percentage of Time Patients Experience AEs During First 12 Months on Vandetanib Treatment
The purpose of this study is to evaluate the effect of patient outreach program on the proportion of time patients with MTC experience moderate or severe AEs during first 12 months of treatment with vandetanib
- Trial name
- NCT01298323
- Testing
- Patient outreach, Vandetanib
- Where
- 66 sites in Australia, Austria and 18 more
- Volunteers
- 205 people
- Sponsor
- Sanofi
Dementia
Targeted Interdisciplinary Model for Evaluation and Treatment of Neuropscyhiatric Symptoms
Almost all people who suffer from dementia experience neuropsychiatric symptoms (NPS) in the course of the disease. TIME (Targeted Interdisciplinary Model for Evaluation and treatment of neuropsychiatric symptoms) is a…
- Trial name
- TIME (NCT02655003)
- Testing
- TIME, Education-only intervention
- Where
- Norway
- Volunteers
- 229 people
- Sponsor
- Sykehuset Innlandet HF
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