Clinical trials: Assessment of Right Ventricular Function
Pulmonary Hypertension, Pulmonary Resistance
Immunoadsorption in Patients With Pulmonary Hypertension
The purpose of this study is to investigate, if Immunoadsorption of autoantibodies with subsequent substitution of immunoglobulins is able to improve haemodynamics in patients with pulmonary hypertension.
- Trial name
- NCT01126411
- Testing
- immunoadsorption / immunglobulin substitution
- Where
- Germany
- Sponsor
- University Medicine Greifswald
Postoperative Complications, Heart Failure
Association Between Portal Flow Pulsatility and Right Ventricular Dysfunction in the Postoperative Period of Cardiac Surgery
Right ventricular dysfunction (RVD) after cardiac surgery is associated with ischemia and myocardial injury. While echocardiographic measures like Tricuspid Annular Plane Systolic Excursion (TAPSE) are frequently used to assess…
- Trial name
- LIFESAVE (NCT06777355)
- Testing
- Transthoracic and Transesophageal echography within 24 hours post cardiac surgery
- Where
- France
- Volunteers
- 32 people
- Sponsor
- CMC Ambroise Paré
Ventricular Function
Assessment of Right Ventricular Volume in Pediatric Patients
Most publication are basing RV volumes on images acquired from the apical window. However, some data have called the practice of basing these images on apical window into question.
- Trial name
- NCT04099810
- Testing
- three-dimensional echocardiography
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital
PAH, Pulmonary Hypertension
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients
Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific background therapy in subjects with World Health…
- Conditions
- PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension
- Trial name
- NCT03626688
- Testing
- Ralinepag
- Where
- 209 sites in United States, Argentina and 31 more
- Volunteers
- 687 people
- Sponsor
- United Therapeutics
Ventilation Therapy; Complications, Right Ventricular Function
Effect of Airway Pressure Release Ventilation on Right Ventricular Function Assessed by Transthoracic Echocardiography
Effects of APRV on right ventricular function in patients with acute respiratory distress syndrome by transthoracic echocardiography
- Conditions
- Ventilation Therapy; Complications, Right Ventricular Function, ARDS, Transthoracic Echocardiography
- Trial name
- NCT05414110
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Right Ventricular Function, Prone Position
Bedside Assessment of Right Ventricular Output Lying in Prone Or Supine
Right ventricular failure (RVF) is a common complication to cardiac surgery, which is associated to mortality, kidney failure, stroke, prolonged mechanical ventilation and ICU stay.
- Conditions
- Right Ventricular Function, Prone Position, Atelectasis, Atelectases, Postoperative Pulmonary
- Trial name
- BAROLO (NCT07632027)
- Testing
- Prone position
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Sahlgrenska University Hospital
Congenital Heart Disease, Thiamine Deficiency
The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart Disease
Currently, research on the effect of thiamine administration during transcatheter closure on the structure and function of the left ventricle by examining levels of matrix metalloproteinase-9 and tissue inhibitor of…
- Conditions
- Congenital Heart Disease, Thiamine Deficiency, Patent Ductus Arteriosus, Ventricular Septal Defect
- Trial name
- NCT06298344
- Testing
- Thiamine
- Where
- Indonesia
- Volunteers
- 86 people
- Sponsor
- Universitas Sumatera Utara
Pulmonary Regurgitation After Repair of Tetralogy of Fallot
Tetralogy of Fallot Seed Grant
Patients with pulmonary regurgitation after surgical correction of ToF over 13 years old will be recruited from the UCSF adult congenital heart disease clinic.
- Trial name
- NCT00722826
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of California, San Francisco
Pediatric Cancer Patients
Tissue Doppler Assessment of Right Ventricle Function in Pediatrics Underwent Chemotherapy
Tissue Doppler assessment of right ventricular function in newly diagnosed pediatric cancer patients underwent chemotherapy in South Egypt Cancer Institute.
- Trial name
- NCT04831359
- Testing
- Doppler ultrasound
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Acute Pulmonary Embolism (PE)
Assessment of Right Ventricular Function After Acute Pulmonary Embolism: a Comparison of Speckle Tracking Strain and Conventional Echocardiographic Parameters
Echocardiographic Assessment: Performed within 24h of PE diagnosis Conventional parameters: TAPSE, RV FAC, RV/LV ratio, tricuspid S', PASP STE parameters: RV free wall longitudinal strain (RVFWS), global longitudinal strain (GLS)…
- Trial name
- NCT07107347
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
CORONARY ARTERY BYPASS
Assessment Of Right Ventricular Function In Patients Undergoing Coronary Artery Bypass Graft In Assiut University
Assessment Of Right Ventricular Function In Patients Undergoing Coronary Artery Bypass Graft In Assiut University
- Trial name
- NCT03275220
- Testing
- 2D Echocardiography and 3D Echocardiography
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Right Ventricular Dysfunction, Cardiac Arrest
Emergency Department Assessment of Right Ventricular Function and Size in the Post Cardiac Arrest Patient
The right side of the heart of often overlooked in patients who are acutely unwell, as the main area of focus when performing echocardiography tends to be the left ventricle.
- Trial name
- NCT03309852
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University of Manitoba
Transthoracic Echocardiography
Evaluation of Right Ventricular Systolic Function by TAPSE Parameter From Subcostal View
The purpose of this study is to validate a new echocardiographic parameter evaluating right ventricular function.
- Trial name
- NCT04490538
- Testing
- Transthoracic echocardiography
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Emergency Medical Service of the Central Bohemian Region, Czech Republic
Transposition of Great Vessels
Physical Training in Transposition of the Great Arteries
In transposition patients after atrial switch operation, the morphological right ventricle serves as the systemic ventricle. These patients often develop signs of heart failure.
- Trial name
- TrainingTGA (NCT00837603)
- Testing
- Training
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Hannover Medical School
Pulmonary Embolism
Assessment of Right Ventricular Function After Acute Pulmonary Embolism Using Speckle Tracking Echocardiography
1. To asses regional RV function in patients presented with acute pulmonary embolism using speckle tracking echocardiography 2. To evaluate its relationship to long term mortality.
- Trial name
- NCT04609605
- Testing
- speckle tracking echocardiography
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Assiut University
Right Ventricular Dysfunction
Role of Echocardiography in the Assessment of Right Ventricular Function in the Pediatric Population With Valvular Pulmonary Stenosis.
Correct assessment of right ventricular function by transthoracic echocardiographic examination in pediatric patients with congenital valvular pulmonary stenosis after Percutaneous Balloon Pulmonary Valvuloplasty
- Trial name
- NCT04960085
- Testing
- echocardiography
- Volunteers
- 50 people
- Sponsor
- Assiut University
Sleep Apnea, Obstructive
Right Ventricular Function in Obstructive Sleep Apnea
The purpose of this study is to determine the structural and functional cardiac alterations in obstructive sleep apne (OSA) independent from systemic and pulmonary arterial hypertension and their correlation to the severity of…
- Trial name
- NCT00640536
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Florence Nightingale Hospital, Istanbul
Pulmonary Hypertension
Targeting the Right Ventricle in Pulmonary Hypertension
This study is looking to see if giving ranolazine to subjects on stable pulmonary hypertension specific therapies but with right ventricular dysfunction (RVEF <45%) would improve their outcome.
- Trial name
- NCT01839110
- Testing
- Ranolazine
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- University of Pennsylvania
Obesity, Spinal Surgery
Haemodynamic Changes During Anaesthesia in the Prone Position, Evaluated Using Transoesophageal Ultrasound
Transoesophageal ultrasound examination before and after prone position.
- Conditions
- Obesity, Spinal Surgery, Anaesthesia, Changes in Left and Right Ventricle Dimension
- Trial name
- NCT02595788
- Testing
- Change from supine to prone position
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
PAH, Pulmonary Hypertension
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
Study ROR-PH-303, ADVANCE EXTENSION, is an open-label extension (OLE) study for participants with WHO Group 1 PAH who have participated in another Phase 2 or Phase 3 study of ralinepag.
- Conditions
- PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension
- Trial name
- NCT03683186
- Testing
- Ralinepag
- Where
- 190 sites in United States, Argentina and 31 more
- Volunteers
- 1,000 people
- Sponsor
- United Therapeutics