Clinical trials: Assisted Reproductive Technique
Pain, Estradiol
Estrogen and Propofol Injection Pain
This prospective observational study investigates the relationship between serum estrogen concentration and the incidence and severity of propofol injection pain (PIP) in female patients undergoing general anesthesia.
- Conditions
- Pain, Estradiol, Assisted Reproductive Techniques
- Trial name
- NCT06929416
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Infertility
Correlating Time-Lapse Parameters Detected by the Eeva™ System With Comprehensive Chromosome Screening Results
The purpose of this research study protocol is to collect imaging data on embryos followed to blastocyst stage (Day 5-6) and correlate Eeva System parameters with comprehensive chromosome screening (CCS) results, implantation and…
- Trial name
- CCS (NCT01635049)
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- Progyny, Inc.
Assisted Reproductive Technology, Infertility
Sperm Micro-swim up Technique; Process and Select in the Same Dish: a Sibling-oocyte-split Design
A sibling-Oocyte-split design will be conducted on oocytes before denudation and divided into two groups : control group (MII oocytes will be injected using sperm processed by Density gradient method) and sample group ( MII…
- Trial name
- NCT05113225
- Testing
- Micro-swim up technique
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Royal Fertility Center, Egypt
Infertility
Eeva™ Pregnancy Investigational Clinical Study: A Postmarket Follow-Up Study
The purpose of this postmarket study is to gather data to evaluate the impact of using Eeva with traditional morphology grading on clinical pregnancy rates.
- Trial name
- EPIC (NCT01671644)
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 104 people
- Sponsor
- Progyny, Inc.
Infertility, Female
Effects of Pentoxifylline and Vitamin E on Pregnancy Rate in Infertile Women Treated by ICSI:
Our findings will provide preliminary clinical evidence to suggest the new experimental treatment approaches, toward female factor infertility treatment with pentoxyfylline.
- Trial name
- NCT03476564
- Testing
- pentoxifylline, Vit E
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Benha University
Male Infertility, Unexplained Infertility
Swim up and Gradient Methods Used in Assisted Reproduction Techniques on DNA Fragmentation of Spermatozoa
Sperms are prepared by sperm washing techniques before used in assisted reproductive technologies. Most commonly used sperm preparation methods are the swim up and the density gradient.
- Trial name
- NCT01859520
- Testing
- swim-up, density gradient sperm preparation techniques
- Volunteers
- 65 people
- Sponsor
- Gazi University
Infertility
An Observational Study to Evaluate Efficacy, Safety and Clinical Outcomes of Currently Used Pharmaceutical Therapies for Controlled Ovarian Stimulation in Assisted Reproductive Techniques
Human gonadotrophins have been successfully used for the treatment of infertility for more than 30 years. This observational study is being conducted to evaluate the efficacy and safety of the gonadotropins used for controlled…
- Trial name
- ESCORT (NCT01149070)
- Where
- Hungary
- Volunteers
- 10,103 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Endometriosis, Infertility
Infertility and Endometriosis Cohort
Nowadays, one in six couples consults for fertility problems. If the standard examination and tests do not reveal any cause of infertility, the woman may undergo a laparoscopic exploration which reveals endometriosis in more than…
- Trial name
- EndoFertil (NCT01833013)
- Testing
- live birth date and quality of life assessment
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Non-viable Oocytes, Extra Spermatozoa
Evaluation of Discarded Laboratory Pathological Specimens and Media
The researchers propose to investigate the causes, incidence, and time-related events of chromosomal and physiologic abnormalities as they relate to patient diagnosis, fertility drugs utilized, and in vitro laboratory culture…
- Conditions
- Non-viable Oocytes, Extra Spermatozoa, Seminal Fluid, Granulosa Cells
- Trial name
- NCT01219439
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
DNA Damage, Granulosa Cells
Predictive Value of Granulosa Cell DNA Damage in the Success of Assisted Reproductive Technique
Deoxyribonucleic acid (DNA) damage of granulosa cells obtained during oocyte retrieval will be evaluated by flow cytometry with detection of Histone H2A.X and Phosphorylated Gamma H2A.X protein levels in patients with low ovarian…
- Trial name
- NCT05558046
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Primary Ovarian Insufficiency, Infertility
In Vitro Follicle Activation
The purpose of this study is to evaluate the effectiveness of an experimental treatment, known as in vitro activation (IVA) of dormant ovarian follicles, for infertility in women diagnosed with primary ovarian insufficiency (POI).
- Trial name
- IVA (NCT02496598)
- Testing
- In Vitro Follicle Activation (IVA), Follicle Activation
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- National Foundation for Fertility Research
Reproductive Techniques, Assisted, DNA Methylation
First Live Birth Rate With eSET After Preimplantation Methylome Screening (PIMS) Versus Conventional In-vitro Fertilization
To determine whether using DNA methylome to select embryos can increase the live birth rate.
- Trial name
- NCT05442125
- Testing
- Using DNA methylome to select embryos, Using morphologic score to select embryos
- Where
- 28 sites in China, Thailand
- Volunteers
- 1,146 people, healthy volunteers welcome
- Sponsor
- Shandong University
Infertility, Ovarian Stimulation
A Prospective Study to Evaluate the Addition of Subcutaneous Recombinant Human-Luteinizing Hormone With Recombinant Human-Follicle Stimulating Hormone on Follicular Development in Women Undergoing Ovarian Stimulation for Assisted Reproductive Technologies
In-vitro fertilization (IVF) of human oocytes followed by the replacement of embryo in the uterine cavity has become a well established treatment for female infertility attributable to damaged fallopian tubes, endometriosis or…
- Trial name
- NCT01121991
- Testing
- Recombinant Human-Luteinizing Hormone (Luveris)
- Volunteers
- 55 people
- Sponsor
- EMD Serono
Infertility, Reproductive Techniques, Assisted
"Study of the Effects of Serum and Follicular Fluid Relaxin Levels on Ovarian Function in IVF Cycles"
The study evaluated the effect of serum relaxin and follicular fluid levels on the number and quality of oocytes, fertilization, the number and quality of the embryos in IVF protocols.
- Conditions
- Infertility, Reproductive Techniques, Assisted, Oocyte Maturation
- Trial name
- "Relaxifert" (NCT04458454)
- Testing
- Relaxin ELISA Kit
- Where
- Russia
- Volunteers
- 11 people
- Sponsor
- D.O. Ott Research Institute of Obstetrics, Gynecology, and Reproductology
Infertility, Reproductive Techniques, Assisted
An Alternative Culture Medium to Better Support Preimplantation Embryo Development in Vitro
The purpose of this research study is to evaluate a newly developed embryo culture media system for human clinical use in ART.
- Trial name
- NCT02457481
- Testing
- Embryo Culture medium
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Foundation for Fertility Research
Reproductive Techniques, Assisted
Use of Acetyl Salicylic Acid and Terbutalin in Assisted Reproductive Techniques (ART)
This study aims to determine the possible effects of Acetyl Salicylic Acid (ASA) and Terbutalin on ART treatment.
- Trial name
- NCT00518141
- Testing
- Acetyl Salicylic Acid and Terbutalin
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Sykehuset Telemark
Assisted Reproductive Techniques
Trends in Live Birth Rates Attributable to Assisted Reproductive Technology in British Columbia
Investigators will examine trends in ART use in BC specifically. The use of ART has drastically changed the management of infertility, with worldwide estimates exceeding 1.8 million ART cycles in 2010 alone.
- Trial name
- NCT04373239
- Testing
- Assisted Reproductive Technology
- Volunteers
- 1,000 people
- Sponsor
- University of British Columbia
Fetal Growth Restriction (FGR), Preeclampsia
Association of Assisted Reproductive Technologies Parameters With the Perinatal Outcome
The goal of this prospective cohort study is to examine how different parameters of assisted reproductive technologies (ART) are associated with the perinatal outcome in individuals with singleton or multiple gestations.
- Conditions
- Fetal Growth Restriction (FGR), Preeclampsia, Stillbirth, Placenta Previa
- Trial name
- NCT06918236
- Where
- 6 sites in Bulgaria, Greece and 1 more
- Volunteers
- 12,084 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Infertility, Female
Biological Effects of Treatment With Resveratrol in ART Patients
To evaluate the effects of a new nutraceutical formulation containing resveratrol (trademark GENANTE) on gamete quality in order to improve the reproductive process during ART.
- Trial name
- NCT04386499
- Testing
- Resveratrol, Folic acid
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Of Perugia
Controlled Ovarian Stimulation
A Study to Assess the Efficacy and Safety of Ganirelix (Orgalutran®) Treatment in Chinese Women Undergoing Controlled Ovarian Stimulation for in Vitro Fertilization (IVF) or Intra Cytoplasmatic Sperm Injection (ICSI) (Study 38651)(P05703)
The primary purpose of this study is to assess that ganirelix is safe and well-tolerated in Chinese women and that a controlled ovarian stimulation (COS) protocol combining recombinant follicle stimulating hormone (recFSH) with…
- Trial name
- NCT00725491
- Testing
- ganirelix, triptorelin
- Volunteers
- 259 people
- Sponsor
- Organon and Co