Clinical trials: Assisted Reproductive Technique
Infertility
Gametes Transfer vs. Embryo Transfer for Women Undergoing Assisted Reproductive Techniques: a Randomized Controlled Trial
Background: The cost for the treatment of infertility are limiting for the health care access, particularly if we consider that the success rate per cycle is approximately 35%.
- Trial name
- NCT01839136
- Testing
- Intrauterine transfer of gametes, Intrauterine transfer of embryos
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Infertility
Correlating Time-Lapse Parameters With aCGH Testing in IVF Treatment (aCGH Study)
The purpose of this research study protocol is to collect imaging data on embryos followed to blastocyst stage (Day 5-6) and correlate Eeva parameters with array - Comparative Genomic Hybridization (aCGH) results and ongoing…
- Trial name
- NCT02141685
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Progyny, Inc.
Infertility
Relationship Between Mid-luteal Serum Progesterone Levels to Pregnancy Rates in Assisted Reproductive Techniques (ART)
In Assisted Reproductive Techniques (ART) there is a need for luteal support using progesterone, estrogen and probably human chorionic gonadotropin (HCG). The optimal route of administration and dose has not yet been determined.
- Trial name
- NCT01356524
- Testing
- Additional vaginal progesterone
- Where
- Israel
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Infertility
Phase 3 Study to Evaluate the Efficacy and Safety of Pergoveris® in Assisted Reproductive Technology (ESPART)
This is a Phase 3, randomized, controlled, single-blind, multicenter, parallel-arm trial to assess the safety and efficacy of Pergoveris® (recombinant human follicle stimulating hormone [r-hFSH]/recombinant human luteinising…
- Trial name
- ESPART (NCT02047227)
- Testing
- Pergoveris®, GONAL-f®, Recombinant human chorionic gonadotrophin (r-hCG)
- Where
- Germany
- Volunteers
- 939 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
In Vitro Fertilization
Comparing the Efficacy of Urinary and Recombinant Human Chorionic Gonadotropin (hCG) on Oocyte Maturity
This study is a prospective randomized clinical trial to compare the efficacy of the urinary and recombinant hCG on oocyte quality for ovulation induction in women undergoing IVF/ICSI.
- Trial name
- NCT01507376
- Testing
- recombinant hCG, urinary hCG
- Where
- Iran
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Assisted Reproductive Techniques
Double Stimulation in Women With Low Prognosis in ART
The main objective of this study is to compare the cumulative ongoing pregnancy rates of two different IVF protocols in women candidate for ART characterized by low prognosis.
- Trial name
- NCT04531644
- Testing
- double stimulation, conventional ovarian stimulation
- Where
- Vietnam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tu Du Hospital
Infertility
Improvement of Cell Selection in Reproductive Techniques
It is the aim of this trial to use a new computerized cell selection method, in addition to the current and world-wide used scoring system of fertilized oocytes implemented by Scott, to determine whether this leads to an increase…
- Trial name
- NCT02610114
- Testing
- Z-Score and computer algorithm, Z-Score
- Where
- Switzerland
- Volunteers
- 220 people
- Sponsor
- Jürgen Weiss
Ovulation Induction, Infertility
An Open Label, Canadian Phase IIIb Study With Ovidrel in Ovulation Induction (OI) and Assisted Reproductive Technique (ART)
With the development of the recombinant gonadotrophins, the use of human source proteins for the production of hormones has become unnecessary.
- Trial name
- NCT01152866
- Testing
- Choriogonadotropin alpha (r-hCG)
- Volunteers
- 3 people
- Sponsor
- EMD Serono
Oocyte Retrieval, Pain
Oocyte Retrieval and Virtual Reality (REVPO)
The aim of the study is to ass wether or not the use of virtual reality during oocyte retrieval provides a better pain relief for patients, compared to a standard analgesic procedure.
- Conditions
- Oocyte Retrieval, Pain, Fertilization in Vitro
- Trial name
- REVPO (NCT04935658)
- Testing
- Hypnotic relaxation induced by virtual reality (device), local anesthesia
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Clermont-Ferrand
Assisted Reproductive Technique, ICSI
Acrosome Reaction Induction Prior to ICSI
Introduction To get through the egg vestment and fertilize the oocyte, the spermatozoon uses its acrosomal enzymes. When Intracytoplasmic sperm microinjection (ICSI) is performed, the acrosomal enzymes are introduced with the…
- Conditions
- Assisted Reproductive Technique, ICSI, Acrosome Reaction, Pregnancy Outcome
- Trial name
- RA-ICSI (NCT02271490)
- Testing
- Acrosome Reaction induction, capacitation in incubation medium prior to ICSI
- Where
- France
- Volunteers
- 111 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fertility Issues
Assisted Reproductive Techniques (ART) With Sperm Donation : an Inclusive Model of ART for All Women
This is a monocentric, retrospective, non-interventional study. The main objective is to describe the populations requesting assisted reproductive techniques (ART) with sperm donation ; and compare them between groups depending…
- Trial name
- PMAPT (NCT06163079)
- Testing
- No intervention
- Where
- France
- Volunteers
- 675 people
- Sponsor
- Central Hospital, Nancy, France
Metabolic Syndrome, Diabetes
Metabolic Phenotyping of Individuals Born Following Assisted Reproduction Techniques
This study is to compare the effects of high fat overfeeding on metabolic risk factors in children born though assisted reproduction technologies (ART) versus children conceived naturally (controls).
- Trial name
- IMPART (NCT01230632)
- Testing
- high fat overfeeding
- Where
- Australia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Reproductive Techniques, Assisted
Effect of a Multivitamin Supplement With Probiotic (Seidivid Ferty4®) on Oocyte Retrieval and Quality
This study evaluates the effect of pretreatment with a multivitamin supplement with probiotics (Seidivid Ferty4®) on oocyte retrieval in normo-responder patients undergoing controlled ovarian hyperstimulation (COH) for oocyte…
- Trial name
- OvoVid (NCT05473039)
- Testing
- Seidivid Ferty4
- Where
- Spain
- Volunteers
- 196 people
- Sponsor
- SEID S.A.