Clinical trials: Assisted Reproductive Techniques
Infertility
Correlating Time-Lapse Parameters With aCGH Testing in IVF Treatment (aCGH Study)
The purpose of this research study protocol is to collect imaging data on embryos followed to blastocyst stage (Day 5-6) and correlate Eeva parameters with array - Comparative Genomic Hybridization (aCGH) results and ongoing…
- Trial name
- NCT02141685
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Progyny, Inc.
Pain, Estradiol
Estrogen and Propofol Injection Pain
This prospective observational study investigates the relationship between serum estrogen concentration and the incidence and severity of propofol injection pain (PIP) in female patients undergoing general anesthesia.
- Conditions
- Pain, Estradiol, Assisted Reproductive Techniques
- Trial name
- NCT06929416
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Assisted Reproductive Techniques
Dual Ovarian Stimulation (Duostim) and Shanghai Protocols in Poor Ovarian Responders
A combination of follicular phase stimulation and luteal phase stimulation in the same cycle, can be a valuable choice in poor responder patients with reduced ovarian reserve, in order to achieve extreme the number of oocytes in…
- Trial name
- NCT06199960
- Testing
- Doustim protocol
- Where
- Iran
- Volunteers
- 116 people
- Sponsor
- Royan Institute
IVF Cycle, Ovarian Stimulation
Efficacy and Safety of Medication Used to Stimulate Ovulation
Individuals undergoing In Vitro Fertilization must undergo controlled ovarian hyperstimulation (COH) to produce enough quality eggs for fertility treatment.
- Conditions
- IVF Cycle, Ovarian Stimulation, Egg Retrieval, Pregnancy
- Trial name
- NCT02715336
- Testing
- Ovulation induction with hCG and Lupron (GnRH agonist)
- Where
- Canada
- Volunteers
- 666 people, healthy volunteers welcome
- Sponsor
- Create Fertility Center
Infertility
Endometrial Injury for Assisted Reproduction
The objective of this study is to evaluate the effect of endometrial injury performed prior ovulation induction for assisted reproductive techniques main outcomes.
- Trial name
- NCT01132144
- Testing
- Endometrial injury, Control group
- Where
- Brazil
- Volunteers
- 158 people
- Sponsor
- University of Sao Paulo
Controlled Ovarian Stimulation
A Study to Assess the Efficacy and Safety of Ganirelix (Orgalutran®) Treatment in Chinese Women Undergoing Controlled Ovarian Stimulation for in Vitro Fertilization (IVF) or Intra Cytoplasmatic Sperm Injection (ICSI) (Study 38651)(P05703)
The primary purpose of this study is to assess that ganirelix is safe and well-tolerated in Chinese women and that a controlled ovarian stimulation (COS) protocol combining recombinant follicle stimulating hormone (recFSH) with…
- Trial name
- NCT00725491
- Testing
- ganirelix, triptorelin
- Volunteers
- 259 people
- Sponsor
- Organon and Co
Infertility, Genetic Diseases
Time-Lapse Incubation for Embryo Culture - Morphokinetics and Environmental Stability
Embryo culture and selection has been a continuous challenge in evolution since the birth of In Vitro Fertilization (IVF). Traditionally, embryo quality and its presumed suitability for transfer were assessed based on morphologic…
- Trial name
- NCT02657811
- Testing
- Miri, Benchtop Multi-room incubator, Miri TL, Time-Lapse incubator
- Where
- Israel
- Volunteers
- 372 people
- Sponsor
- Shaare Zedek Medical Center
Infertility
Recurrent Failures in assIsted Reproductive Techniques (The FIRST Registry)
Assisted Reproductive Technologies (ARTs) are widely used in couples with fertility problems. However, despite ART treatment options have evolved over time, the implantation rate remains rather low.
- Trial name
- NCT02685800
- Where
- Italy
- Volunteers
- 624 people
- Sponsor
- Casa Sollievo della Sofferenza IRCCS
Infertility
Phase 3 Study to Evaluate the Efficacy and Safety of Pergoveris® in Assisted Reproductive Technology (ESPART)
This is a Phase 3, randomized, controlled, single-blind, multicenter, parallel-arm trial to assess the safety and efficacy of Pergoveris® (recombinant human follicle stimulating hormone [r-hFSH]/recombinant human luteinising…
- Trial name
- ESPART (NCT02047227)
- Testing
- Pergoveris®, GONAL-f®, Recombinant human chorionic gonadotrophin (r-hCG)
- Where
- Germany
- Volunteers
- 939 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Infertility, Ovarian Stimulation
A Prospective Study to Evaluate the Addition of Subcutaneous Recombinant Human-Luteinizing Hormone With Recombinant Human-Follicle Stimulating Hormone on Follicular Development in Women Undergoing Ovarian Stimulation for Assisted Reproductive Technologies
In-vitro fertilization (IVF) of human oocytes followed by the replacement of embryo in the uterine cavity has become a well established treatment for female infertility attributable to damaged fallopian tubes, endometriosis or…
- Trial name
- NCT01121991
- Testing
- Recombinant Human-Luteinizing Hormone (Luveris)
- Volunteers
- 55 people
- Sponsor
- EMD Serono
Chronic Endometritis
Diagnosis of Chronic Endometritis in Endometrial Fluid Using Molecular Techniques to Improve the Outcomes of Assisted Reproductive Treatments
Chronic endometritis (CE) is a persistent inflammation of the endometrial lining caused by the infection of the uterine cavity mainly by bacterial pathogens.
- Trial name
- ChEndometritis (NCT03169621)
- Testing
- Endometrial Biopsy and endometrial fluid collection
- Where
- Spain
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Igenomix
Infertility
Impact of Meditation and Reiki on Assisted Reproduction Techniques Outcomes
Infertility is estimated to affect 15% of reproductive age couples worldwide and is defined as the inability to conceive after 12 months of unprotected sex for women under 35 or 6 months for women over 35 and is associated with…
- Trial name
- NCT04058262
- Testing
- Meditation presential, Reiki, Meditation (app)
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Federal University of Minas Gerais
Reproductive Techniques, Assisted
Use of Acetyl Salicylic Acid and Terbutalin in Assisted Reproductive Techniques (ART)
This study aims to determine the possible effects of Acetyl Salicylic Acid (ASA) and Terbutalin on ART treatment.
- Trial name
- NCT00518141
- Testing
- Acetyl Salicylic Acid and Terbutalin
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Sykehuset Telemark
Assisted Reproductive Technology
Oocyte Activation: Revised or Initial AGT Technique, Which is Better?! A Sibling-oocytes-split Design
This study will be conducted to compare two different Assisted Gamete treatment (AGT) with oocyte-sibling-split design control group : AGT- initial protocol for activating oocytes by culturing oocytes in calcium ionophore after…
- Trial name
- NCT05113238
- Testing
- Assisted gamete activation
- Where
- Egypt
- Volunteers
- 222 people
- Sponsor
- Royal Fertility Center, Egypt
Infertility
Improvement of Cell Selection in Reproductive Techniques
It is the aim of this trial to use a new computerized cell selection method, in addition to the current and world-wide used scoring system of fertilized oocytes implemented by Scott, to determine whether this leads to an increase…
- Trial name
- NCT02610114
- Testing
- Z-Score and computer algorithm, Z-Score
- Where
- Switzerland
- Volunteers
- 220 people
- Sponsor
- Jürgen Weiss
Reproductive Techniques, Assisted
Effect of a Multivitamin Supplement With Probiotic (Seidivid Ferty4®) on Oocyte Retrieval and Quality
This study evaluates the effect of pretreatment with a multivitamin supplement with probiotics (Seidivid Ferty4®) on oocyte retrieval in normo-responder patients undergoing controlled ovarian hyperstimulation (COH) for oocyte…
- Trial name
- OvoVid (NCT05473039)
- Testing
- Seidivid Ferty4
- Where
- Spain
- Volunteers
- 196 people
- Sponsor
- SEID S.A.
Infertility, Female, Reproductive Techniques, Assisted
SISTER: Sibling Oocyte Insemination With Frozen Sperm From Third Party Donors: Evaluation of Reproductive Techniques
The goal of this clinical trial is to learn whether two different methods of helping eggs and sperm join-intracytoplasmic sperm injection (ICSI) and conventional in vitro fertilization (IVF)-lead to better embryo development when…
- Conditions
- Infertility, Female, Reproductive Techniques, Assisted, Fertilization in Vitro
- Trial name
- SISTER (NCT07175571)
- Testing
- Intracytoplasmic Sperm Injection (ICSI), Conventional Insemination (IVF)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Infertility, Ovulation Induction
To Evaluate the Convenience, Safety and Efficacy of Follitropin Alfa Liquid Pen Compared With Follitropin Beta Liquid Pen
This was a prospective, randomised, open comparative monocentric phase IIIb study to evaluate the convenience, safety and efficacy of follitropin alfa (Gonal-f) liquid pen compared with follitropin beta (Puregon) liquid pen.
- Trial name
- NCT01081639
- Testing
- Follitropin alfa liquid formulation, Follitropin beta liquid formulation
- Volunteers
- 34 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Infertility
Eeva 12-well Dish Study
The purpose of this study is to demonstrate that the Eeva™ System is compatible with the Eeva 12-well Dish.
- Trial name
- NDS (NCT01635036)
- Testing
- In-vitro fertilization using Eeva
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Progyny, Inc.
Reproductive Techniques, Assisted
Clinical Trial Comparing Endometrial Transformation With Subcutaneous Progesterone Versus Intramuscular Progesterone
Study the endometrial predecidualization by using subcutaneous progesterone 25 mg/day versus intramuscular progesterone 50 mg/day, to determine whether there are differences in the endometrial transformation and endometrial…
- Trial name
- NCT02567552
- Testing
- Subcutaneous progesterone, Intramuscular progesterone
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- IVI Barcelona