Clinical trials: Assisted Reproductive Technology
Assisted Reproductive Technology
Progesterone Supplementation on Women Having Low Progesterone Levels on Transfer Day
The main objective of this study is to compare clinical pregnancy rates between two groups of women who have progesterone levels below 10 ng/mL on the day of frozen embryo transfer: group 1 (vaginal micronized progesterone…
- Trial name
- NCT04897269
- Testing
- Progesterone supplementation
- Where
- Vietnam
- Volunteers
- 824 people, healthy volunteers welcome
- Sponsor
- Tu Du Hospital
Infertility Assisted Reproductive Technology, Infertility (IVF Patients)
Blastocyst AI Assisted Morphokinetics in ART
The goal of this observational study is to learn if embryo characteristics obtained via the recording of real-time embryo activity via 30-seconds video capture (e.g.: Embryo Morphokinetics) can correlate with known embryo outcome…
- Trial name
- AIM (NCT07611448)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Viable Biosciences
Infertility
Sperm Selection for Infertility Treatment (SSA)
Infertility is considered a disease by the World Health Organization and it is increasing worldwide affecting more than 70 million couples. About 50% of the cases are due to male inability to fertilize the oocyte.
- Trial name
- SSA (NCT02867111)
- Testing
- Sperm Selection Assay, Attractant Substance, ICSI
- Where
- 2 sites in Argentina
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Córdoba
Assisted Reproductive Technology, Controlled Ovarian Hyperstimulation
Efficacy and Safety of BG2109 During Controlled Ovarian Hyperstimulation in Female Subjects Undergoing ART Procedures
To explore the optimal effective daily dose of BG2109 to suppress premature luteinizing hormone (LH) surge during COH in female subjects undergoing ART procedures.
- Trial name
- NCT05738382
- Testing
- BG2109, Cetrorelix
- Where
- 10 sites in China
- Volunteers
- 240 people
- Sponsor
- Bio Genuine (Shanghai) Biotech Co., Ltd.
Health Related
Newborns From Patients Treated With ART (Assisted Reproductive Technology)
The Prospective Cohort Study for Newborns from patients treated with ART was set up to investigate the short- and long-term health consequences in Reproductive Medical Center, First Affiliated Hospital of Zhengzhou University…
- Trial name
- NCT03993158
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Infertility, Female, Intracytoplasmic Sperm Injections
Piezo-ICSI to Improve the Developmental Potential of Fertilized Oocytes in Aged Infertility Women With Assisted Reproductive Technology
The goal of this clinical trial is to test Piezo-ICSI on improving oocyte fertilization and embryo development in elderly infertile patients undergoing intracytoplasmic sperm injection (ICSI).
- Trial name
- NCT06459778
- Testing
- Piezo-ICSI
- Where
- China
- Volunteers
- 147 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Infertility, Infertility Assisted Reproductive Technology
A Large-scale, Prospective Cohort Study Was Conducted to Explore the Association Between Environmental Exposure and Behavioral Factors and Infertility (the Success Rate of Assisted Reproductive Technology)
The aim is to explore the reasons for the failure of assisted reproductive technology (ART) in infertile patients in Hunan Province and seek ways to improve the success rate of ART.
- Conditions
- Infertility, Infertility Assisted Reproductive Technology, Infertility (IVF Patients)
- Trial name
- NCT07641387
- Testing
- Life Style Intervention, Environmental exposure
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Assisted Reproductive Technology, Infertility
Sperm Micro-swim up Technique; Process and Select in the Same Dish: a Sibling-oocyte-split Design
A sibling-Oocyte-split design will be conducted on oocytes before denudation and divided into two groups : control group (MII oocytes will be injected using sperm processed by Density gradient method) and sample group ( MII…
- Trial name
- NCT05113225
- Testing
- Micro-swim up technique
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Royal Fertility Center, Egypt
Subclinical Hypothyroidism, Infertility
Levothyroxine Treatment and IVF Outcomes in Women With Subclinical Hypothyroidism: A Target Trial Emulation
Subclinical hypothyroidism (SCH) is defined by elevated thyroid-stimulating hormone (TSH) with normal free thyroxine (fT4) levels.
- Conditions
- Subclinical Hypothyroidism, Infertility, Assisted Reproductive Technology, In Vitro Fertilization (IVF)
- Trial name
- LESI (NCT07257250)
- Where
- 2 sites in Vietnam
- Volunteers
- 900 people
- Sponsor
- Mỹ Đức Hospital
Ovarian Hyperstimulation Syndrome
Compare the Efficacy of Human Albumin With Cabergoline to Prevent Ovarian Hyper Stimulation in Assisted Reproductive Technology (ART) Program
The purpose of this study is to investigate the efficacy and safety of cabergoline in prevention of ovarian hyperstimulation syndrome versus albumin in ART program.
- Trial name
- NCT01009567
- Testing
- Cabergoline, Control
- Where
- Iran
- Volunteers
- 10 people
- Sponsor
- Royan Institute
Assisted Reproductive Technology, Assisted Reproductive Technology Outcomes
Sperm Selection Strategies and Male-Factor Phenotypes in ICSI
This retrospective multicentre observational cohort study evaluates clinical and reproductive outcomes associated with different sperm-selection strategies used during intracytoplasmic sperm injection (ICSI), including…
- Trial name
- ANDRO-ART (NCT07825584)
- Testing
- Conventional ICSI, Hyaluronan-Binding Sperm Selection, ZyMōt
- Where
- 10 sites in Poland
- Volunteers
- 12,561 people
- Sponsor
- Center for Reproductive Medicine Bocian
Infertility
A Non-interventional Study to Identify the Patients With Severe Luteinizing Hormone Deficiency in the Daily Practice
This non-interventional study is planned to identify the subjects with severe luteinizing hormone (LH) deficiency in the daily practice.
- Trial name
- NCT01112618
- Where
- Germany
- Volunteers
- 3,247 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Infertility
Physiotherapy in Assisted Reproductive Treatment
Research examines the effect of physiotherapy on treatment success by assisted reproductive technologies. It is based on a treatment of infertility by physiotherapeutic intervention after which the participants will undergo a…
- Trial name
- NCT04971824
- Testing
- Physiotherapeutic intervention
- Where
- Czechia
- Volunteers
- 42 people
- Sponsor
- Klaudia Fabičovic, PT
Fertility Issues
Study to Investigate the Treatment Benefit of Probiotic Lactobacillus Crispatus M247 in Women Undergoing Homologous Level 2 Assisted Reproductive Technology (ART) Procedures
The present study is aimed to explore the treatment effect from the intake of probiotic Lactobacillus crispatus M247 in the improvement of clinical and psychological aspects in women undergoing homologous level 2 ART procedures.
- Trial name
- NCT05871242
- Testing
- Probiotic Lactobacillus crispatus M247
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Dr. Amjad Khan
Embryo Quality
Group Culture May Affect Embryo Quality in Assisted Reproduction Technology
One of the vital factors in achieving pregnancies in assisted reproductive technologies (ART) is maximizing embryo quality, which is significantly influenced by embryo culture conditions.
- Trial name
- NCT04011319
- Testing
- group culture
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Infertility
Stress in Couples Undergoing Assisted Reproduction Technology With Different Cycles and Its Impact on Pregnancy Outcomes
With the development of assisted reproductive technology (ART), more and more infertile women are obtaining their offspring through assisted reproductive technology.
- Trial name
- NCT05055245
- Testing
- cycles
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Fetal Cardiac Disorder
Fetal Cardiac Remodeling in Singleton Pregnancies Conceived by Assisted Reproductive Technology (Biopsied and Non-Biopsied ICSI) Versus Those Normally Conceived
The study aims to assess the presence of fetal cardiac remodeling and dysfunction in singleton pregnancies conceived by assisted reproductive technology (Biopsied and Non-Biopsied ICSI) as compared with those conceived…
- Trial name
- NCT05172336
- Where
- Egypt
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Wael Elbanna Clinic
Infertility, Female, Pregnancy Related
Low TGF-β and Embryo Implantation in the Context of Assisted Reproductive Technology: Confirmation of a Biomarker Predictive of Success and Characterization of the Immune Microenvironment.
Infertility affects about one in seven couples in France. Beyond the medical and personal challenges, it has major societal implications.
- Trial name
- ImmuNoFertilit (NCT07859930)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
COVID-19
Retrospective Study of COVID-19 on Reproductive Function
This multi-center, retrospective cohort study aimed to determine which factors are associated with ongoing pregnancy rates in infertile patients received ART treatments during the current outbreak of COVID-19 infection.Couples…
- Trial name
- NCT05685966
- Testing
- no intervention
- Where
- 3 sites in China
- Volunteers
- 400 people
- Sponsor
- Jinling Hospital, China
Infertility
A Study Using Recombinant Human Chorionic Gonadotrophin (rhCG, Ovidrel®) in the Induction of Final Follicle Maturation and Early Luteinization in Chinese Women Undergoing in Vitro Fertilization and Embryo Transfer (IVF/ET)
This was an open, randomized, comparative study using rhCG (Ovidrel) in the induction of final follicle maturation and early luteinization in Chinese female subjects undergoing IVF or ET.
- Trial name
- NCT01081756
- Testing
- r-hCG, Urinary-hCG
- Where
- China
- Volunteers
- 218 people
- Sponsor
- Merck KGaA, Darmstadt, Germany