Clinical trials: Asthenozoospermia
Asthenozoospermia, Oligospermia
Myo-inositol on Human Semen Parameters
Many clinical evidences suggest that Myo-inositol plays a crucial role in human reproduction. Also, it was shown that Myo-inositol concentration in the seminiferous tubules was higher than in serum, and interestingly it was…
- Trial name
- NCT01828710
- Testing
- Myo-inositol normospermic, Myo-inositol OAT, Folic Acid normospermic
- Where
- Italy
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Subfertility, Asthenozoospermia
Fertility and the Microbiome
With this study, the investigators want to investigate the microbiome and human papilloma virus (HPV) status of couples with subfertility.
- Trial name
- NCT05328999
- Testing
- Probiotics (Omnibiotic (R))
- Where
- Austria
- Volunteers
- 300 people
- Sponsor
- Medical University of Graz
Infertility, Male, Infertility Unexplained
Using of Testes Shocker in Improving the Spermatogenesis and Sperms Activity
Infertility was reported in approximately 15% of all heterozygous couples, with male factor accounting for nearly half the cases.
- Conditions
- Infertility, Male, Infertility Unexplained, Infertility Due to Complete Spermatogenic Arrest, Oligospermia
- Trial name
- NCT05506722
- Testing
- Testes shocker
- Where
- Iraq
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Asthenozoospermia
The Effect of Oral Zinc Supplementation on Thiol Oxido-reductive Index
Although several studies have considered the relationship between infertility and semen thiol compounds levels, no study on the effects of asthenospermia treatments such as oral zinc supplementation on thiol related enzymes…
- Trial name
- NCT02985905
- Testing
- zinc sulfate
- Where
- Iraq
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- mahmoud hussein hadwan
Efficacy and Safety of Shen Hai Long Capsule for Mild to Moderate Asthenospermia in Men
Shen Hai Long Capsule for Male Asthenospermia
To evaluate the efficacy and safety of Shen Hai Long Capsule in the treatment of mild to moderate asthenospermia in men.
- Trial name
- NCT05745610
- Testing
- Shen Hai Long Capsule, Sheng Jing Capsule
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhongnan Hospital
Oligozoospermia and/or Asthenozoospermia
A Study to Evaluate the Safety and Efficacy of Multiple Dose of STSP-0902 in Patients With Oligozoospermia and/or Asthenozoospermia.
This is a Phase 2, randomized, double-blind, placebo-controlled, multiple dose study to evaluate the safety, efficacy, pharmacokinetics, and immunogenicity of STSP-0902 in Patients with Oligozoospermia and/or Asthenozoospermia.
- Trial name
- NCT07833943
- Testing
- STSP-0902 injection
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Staidson (Beijing) Biopharmaceuticals Co., Ltd
Asthenozoospermia
Epididymal U.S Findings in Asthenozoospermic &Correlation With L.Carnitine Level
To evaluate the epididymal findings by U.S and study its correlation with seminal parameters including L.carnitine level in infertile males
- Trial name
- NCT05436080
- Testing
- U/S
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Reduced Sperm Motility, IVF
Sperm Selection and Embryo Development: Comparison of the Density Gradient Centrifugation and Microfluidic Chip Sperm Preparation Methods Sperm Selection and Embryo Development: Comparison of the Density Gradient Centrifugation and Microfluidic Chip Sperm Preparation Methods
Purpose: To compare the effects of the density gradient centrifugation and microfluidic chip sperm preparation methods on embryo development in a study population with astheno-teratozoospermia.
- Conditions
- Reduced Sperm Motility, IVF, ICSI, Astheno Teratozoospermia
- Trial name
- NCT04962074
- Testing
- Microfluidic sperm sorting chip, Density gradient
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Maltepe University
Infertility, Male, Azoospermia
The Association of Gut Microbiota and Spermatogenic Dysfunction
This is a multicenter, case-control study that aims to investigate the relationship between microbiota and sperm quality via stool, blood, and urine microbiome, metabolomics, and collected clinical metadata.
- Conditions
- Infertility, Male, Azoospermia, Oligozoospermia, Asthenozoospermia
- Trial name
- NCT05628987
- Testing
- no intervention
- Where
- 3 sites in China
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Asthenozoospermia, Mitochondrial Damage
Evaluation of the Effects of Semen Incubation With ANDROSITOL®DGN on Sperm Motility and Mitochondrial Membrane Potential
Mitochondria is the cellular organelle responsible for the production of the energy necessary to fuel sperm motility. It has been demonstrated that mitochondrial efficiency is correlated to the fertilizing capacity of the…
- Trial name
- Androsi-Test (NCT04291495)
- Testing
- ANDROSITOL®TEST
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Catania
Asthenozoospermia
Effect of Antioxidant Food Supplement on Sperm Proteomic Structure and Semen Parameters
Infertility is defined as the inability to become pregnant despite 12 months of regular and unprotected intercourse. Male factors include defects in sperm concentration, morphology and motility, among which low sperm motility…
- Trial name
- Asthenospermia (NCT05826782)
- Testing
- Proxeed Plus 2*1 A arm
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kocaeli University
Infertility Unexplained
Effect of Oral Zinc Sulfate Supplementation on Enzymes of Urate Pathway
Although many reports have investigated the relationship between subfertility and uric acid levels in semen, to the best of author knowledge, there is no study have been published to yet focus on the effects of asthenospermia…
- Trial name
- NCT03361618
- Testing
- Zinc Sulfate
- Where
- Iraq
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Babylon University
Asthenozoospermia
Study the Effect of Oral Zinc Supplementation on Enzymes of Nitric Oxide Pathway
The ability of spermatozoa to produce reactive oxygen species (ROS) has been respected since the 1940's. Oxidative stress limits the functional competence of mammalian spermatozoa via lipid peroxidation, the induction of…
- Trial name
- NCT01684059
- Testing
- zinc sulfate
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- Babylon University
Male Infertility
Administration of Antioxidants to Infertile Men and Sperm Quality
The purpose of this randomized clinical trial is to assess the effect of oral antioxidant administration to infertile men, by evaluating semen variables, sperm DFI and levels of ROS.
- Trial name
- NCT04256278
- Testing
- Spermotrend
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Aristotle University Of Thessaloniki
Male Infertility, Asthenozoospermia
Efficacy and Safety of Linggui Yangyuan Paste in Patients With Male Infertility
Male infertility affects millions of males worldwide and is rising in prevalence due to social and environmental conditions. Asthenozoospermia (AZS) and oligoasthenozoospermia (OA) are the major causes of male infertility.
- Conditions
- Male Infertility, Asthenozoospermia, Oligoasthenozoospermia
- Trial name
- NCT05792813
- Testing
- LGYY, LGYY mimetic, WZYZ
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Asthenozoospermia
Effect of Pentoxifylline + CoQ10 vs CoQ10 Alone on Sperm Motility in Subfertile Men With Asthenozoospermia
The goal of this clinical trial is to learn if drug Pentoxifylline plus Coenzyme Q10 work to treat asthenozoospermia in subfertile male. It will also learn about the safety of drug Pentoxifylline plus Coenzyme Q10.
- Trial name
- NCT07252518
- Testing
- Coenzyme Q 10, Pentoxifylline 400 MG Oral Tablet
- Where
- Bangladesh
- Volunteers
- 56 people
- Sponsor
- Mst.Sumyara Khatun
Asthenozoospermia
Study the Effect of Oral Zinc Supplementation on High Molecular Weight Zinc Binding Protein in Semen
There are several causes leading to male infertility, like oxidative stress, and nutritional deficiency of trace elements like zinc.
- Trial name
- supplement (NCT01612403)
- Testing
- zinc sulfate
- Where
- 2 sites in Iraq
- Volunteers
- 37 people
- Sponsor
- mahmoud hussein hadwan