Clinical trials: Asthma, Bronchial
Bronchial Asthma
Risk of Chronic Kidney Disease in Bronchial Asthma
the study aims to determine the frequency and factors associated with chronic kidney disease among asthmatic patients in order to determine persons who are at risk of developing chronic kidney disease and require strict follow up…
- Trial name
- NCT06472596
- Testing
- CBC, CRP ,ESR, ABG , interleukin 6, tumor necrotic factor alpha
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Bronchial Asthma
Biochemical Role of Long Non-coding RNA MALAT 1 and Serum Tumor Necrosis Factor Alpha in Bronchial Asthma Patients.
Bronchial asthma affects more than a quarter of a billion people worldwide. It is responsible for over 1000 deaths a day, of which the majority are preventable (Levy, 2015).
- Trial name
- NCT06459895
- Testing
- Long non-coding MALAT1 gene expression assay:
- Where
- Egypt
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Sohag University
Critical Illness, Asthma
Ketamine Efficacy for Acute Severe Bronchospasm in ICU: MACANUDO Trial
Despite few scientific evidence that could support the use of ketamine in adult patients undergoing acute bronchospasm requiring mechanical ventilation (MV), ketamine is largely employed in this setting.
- Conditions
- Critical Illness, Asthma, Bronchospasm
- Trial name
- MACANUDO (NCT03000413)
- Testing
- Ketamine, Fentanyl
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Hospital Nossa Senhora da Conceicao
Bronchial Asthma
A Study to Assess Jia Wei Yang He Formula as a Plus Therapy in the Treatment of Persistent Asthma
Investigators aimed to assess Jia Wei Yang He Formula as a plus therapy in the treatment of persistent asthma and to explore Airway Microbiome variation of Asthma by Traditional Chinese Medicine treatment
- Trial name
- NCT03299322
- Testing
- Jia Wei Yang He granule
- Where
- 8 sites in China
- Volunteers
- 240 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Asthma
Efficacy and Safety Study of Benralizumab in Patients With Uncontrolled Asthma on Medium to High Dose Inhaled Corticosteroid Plus LABA (MIRACLE)
This is a randomised, double-blind, parallel group, placebo-controlled study designed to evaluate the efficacy and safety of a fixed 30 mg dose of benralizumab administered subcutaneously for patients with a history of asthma…
- Trial name
- NCT03186209
- Testing
- Benralizumab
- Where
- 79 sites in China, Philippines and 2 more
- Volunteers
- 695 people
- Sponsor
- AstraZeneca
Bronchial Asthma
Pattern Of Isolated Fungi From Bronchoalveolar Lavage Among Patients With Bronchial Asthma
This study is to assess the pattern of isolated fungi from the respiratory air way (bronchial tree) from bronchoalvealar lavage (BAL) in asthmatic patients with uncontrolled or difficult to treat asthma
- Trial name
- NCT06376617
- Testing
- fibroptic bronchoscopy
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Bronchial Asthma
REspiratory diSEAse cohoRt Studies of CHinese Medicine for Asthma (RESEARCH- Asthma)
The purpose of this study is to define the standard use of TCM treatment regimen as the TCM cohort group and the non-TCM cohort group of those who use conventional Western medicine treatment without the standard TCM treatment…
- Trial name
- NCT06373692
- Where
- China
- Volunteers
- 1,508 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Bronchial Asthma
Setting a PERSONalized Outcome in ASthma: the PERSONAS Study. A Patient Driven Outcome (PDO) Study
To optimize the effectiveness of asthma therapy there is a need to identify and address individual patient goals. Considering the self-management discussion as central for the achievement of health outcomes, Healthcare Providers…
- Trial name
- PERSONAS (NCT06320119)
- Testing
- PDO Group
- Where
- 12 sites in Italy
- Volunteers
- 190 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Bronchial Asthma
Bronchial Asthma & Its Exacerbation
Our goals is to assess : 1¬_ the role of spirometer in case of asthma exacerbation 2_hematological parameters (N/L ratio \& platelet indices \&CRP )in asthma exacerbation for diagnosing and classifying asthma severity and…
- Trial name
- NCT06331897
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Bronchial Asthma
Two Doses of the Intravenous Magnesium Sulfate Versus the Standard Single Dose ,With/ Without the Nebulized Budesonide For the Management of the Severe Asthma Exacerbation in the Emergency Room; A Randomized Controlled Trial.
Many studies have investigated the efficacy and safety of Intravenous magnesium sulfate and inhaled steroids in addition to the standard treatment for patients with severe asthma attacks.
- Trial name
- NCT02455687
- Testing
- Hi-dose iv MgSO4, Nebulized budesonide, Std-dose iv MgSO4
- Where
- Qatar
- Volunteers
- 240 people
- Sponsor
- Hamad Medical Corporation
Bronchial Asthma
Comparative Effectiveness Study of Constant-Load Versus Graded Aerobic Exercise in Obese Children With Bronchial Asthma
This study aimed to compare the effect of constant-load aerobic exercise (CL-AE) and graded aerobic exercise (G-AE) on cardiopulmonary fitness, and functional capacity in a cohort of obese children with bronchial asthma (BA).
- Trial name
- NCT06326632
- Testing
- Constant-load Aerobic Exercise, Graded Aerobic exercise, Respiratory Re-training
- Where
- Saudi Arabia
- Volunteers
- 78 people
- Sponsor
- Cairo University
Asthma; Eosinophilic, Asthma Chronic
Characteristics of Type 2- High Inflammatory Endotype of Asthma Using New Biomarkers From Peripheral Blood and Exhaled Air and Its Effect on the Outcome of Therapy
The goal of this study is to identify reliable, valid, easily measurable, interpretable, and useful biomarkers in peripheral blood and exhaled air by people with severe asthma for a more accurate description of the pathogenetic…
- Conditions
- Asthma; Eosinophilic, Asthma Chronic, Bronchial Asthma, Asthma, Bronchial
- Trial name
- NCT05270278
- Where
- Czechia
- Volunteers
- 89 people
- Sponsor
- Value Outcomes Ltd.
Bronchial Asthma, Adherence, Medication
Efficacy of a Phone Application on Treatment Adherence in Asthmatic Patients in Upper Egypt
asthma adherence is mandatory for disease control
- Trial name
- NCT06233123
- Testing
- the Medisafe android application (https://www.medisafe.com).
- Volunteers
- 180 people
- Sponsor
- Assiut University
Evaluation of Cardiac Burden in Patients With Sever Bronchial Asthma
Evaluation of Cardiac Burden in Patients With Sever Bronchial Asthma
Evaluation of cardiac burden in patients with sever bronchial asthma
- Trial name
- NCT06223581
- Testing
- ECHO in sever asthma patient
- Volunteers
- 30 people
- Sponsor
- Assiut University
Bronchial Asthma, Adherence, Medication
Cognitive and Emotional Factors Relation to Treatment Adherence in Asthmatic Patients in Upper Egypt
Non-adherence to controller therapy is one of the main reasons of poor asthma control. Adherence to medication in different studies range between 30 and 70% .
- Trial name
- NCT06200623
- Volunteers
- 138 people
- Sponsor
- Entsar Hsanen
Bronchial Asthma
Assessment of Bronchial Asthma Among Patients Attending Sohag University Hospital
Asthma is a significant public health threat, affecting more than 300 million individuals globally. Asthma is classified as a non-communicable disease and leads to reduced quality of life, poor physical functioning and reduced…
- Trial name
- NCT06141161
- Testing
- corticosteroids
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Bronchial Asthma
Two Inhalation Methods Using a Pressurized Metered Dose Inhaler With Valved Holding Chamber to Assess Improvement in Lung Function After SABA Administration in Bronchial Asthma
Bronchial asthma is a chronic inflammatory disorder characterized by recurrent reversible episodes of breathlessness, wheezing, chest tightness and/ or cough.
- Trial name
- NCT05428956
- Testing
- Single Inhalation technique, Tidal inhalation technique
- Where
- 2 sites in India
- Volunteers
- 897 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Esophageal Atresia
Respiratory Complications of Operated Esophageal Atresia in Children
The respiratory complications of esophageal atresia have already been identified. They are mainly related to tracheomalacia linked to the esophageal malformation, and are aggravated by frequently associated gastroesophageal…
- Trial name
- ATRESIA (NCT05527873)
- Where
- France
- Volunteers
- 67 people
- Sponsor
- University Hospital, Strasbourg, France
Bronchial Hyperreactivity
Methacholine Challenge Testing: Comparison of FEV1 and IOS Parameters in Adult Asthma Patients
A classic methacholine challenge test is considered positive when forced expiratory volumen after one second (FEV1) decrease 20%.
- Trial name
- NCT06034145
- Testing
- No intervention
- Volunteers
- 500 people
- Sponsor
- Allergi- og Lungeklinikken, Elsinore
Adhd, ALS
National Multicenter Interventional Study Aimed at Evaluating the Effect on the Intestinal Microbiota in Chronically Frail Patients Who Share Alterations in Intestinal Function.
The objective of the study will be to understand whether a supplementation of the diet with an active symbiotic, i.e. characterized by a mix of probiotics and a specially selected fiber with prebiotic activity combined with a…
- Conditions
- Adhd, ALS, Bronchial Asthma
- Trial name
- sPATIALS3 (NCT06005506)
- Testing
- Prebiotic fiber, Dietary fiber, Probiotic
- Where
- 4 sites in Italy
- Volunteers
- 64 people
- Sponsor
- Institute of Biomedical Technologies-National Research Council, Italy