Clinical trials: Asthma/ COPD
COPD (Chronic Obstructive Pulmonary Disease), Asthma (Diagnosis)
Validation of 1 Minute Sit-to Stand Test for Assessment of Breathlessness at Exertion in Individuals With Chronic Lung Disease
Breathlessness is a common symptom in people with chronic lung and heart diseases. It can affect daily activities, quality of life, and overall health.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Asthma (Diagnosis), Interstitial Lung Disease (ILD)
- Trial name
- V1BE (NCT07836764)
- Testing
- 1MSTS
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Jacob Sandberg
Airway Obstruction, Asthma
Effects of Combined Respiratory Muscle Training and Steam Inhalation
The purpose of this investigation is to obtain more information on the efficacy and safety of respiratory training methods with WellO2 in patients with asthma and COPD.
- Conditions
- Airway Obstruction, Asthma, COPD
- Trial name
- NCT04584398
- Testing
- Respiratory muscle training with steam inhalation
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- WellO2 Oy
Pulmonary Disease, Chronic Obstructive, Asthma COPD
Impact of a Mobile Phone and Educational Intervention
The purpose of this pilot study was to: 1. partner with African American churches to increase awareness of COPD. 2. use a community-based approach to facilitate early detection of COPD in the church setting.
- Trial name
- NCT06878898
- Testing
- Education and mobile phone text-messaging, Education only
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Kent State University
Pulmonary Disease, Chronic Obstructive, Asthma
Berodual® Respimat® Versus Berodual® Metered Aerosol (MA) Inhaler in Patients With Asthma, Chronic Obstructive Pulmonary Disease, or Mixed Condition
The primary objective of this study was to investigate patients acceptability / preference of Berodual® Respimat® inhaler as compared to the conventional Berodual® Metered Aerosol (MA) inhaler.
- Trial name
- NCT02173795
- Testing
- Berodual® Respimat®, Berodual® MA HFA
- Volunteers
- 245 people
- Sponsor
- Boehringer Ingelheim
Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease)
The Improvement of Indoor Air and Health Effects After Air Purifier Intervention Among Susceptible Population in Industrial Area
Invesitigators conducted a double-blind, randomized, and crossover study to investigate the effects of PCO and PCO + filters interventions on indoor air pollutants in households and health outcomes in susceptible group, such as…
- Trial name
- NCT07069907
- Testing
- Air purfiers with photocatalytic oxidation (PCO), Air purfiers with photocatalytic oxidation (PCO) + filters
- Where
- Taiwan
- Volunteers
- 140 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Patient Satisfaction
Study to Evaluate Satisfaction and Usability of DuoResp® SPIROMAX® in Asthma and COPD Treatment
The main aim of the study is to investigate patient satisfaction in the treatment of asthma and COPD with the new device of DuoResp® Spiromax® and patient preference.
- Trial name
- NCT02384577
- Testing
- Budesonide, Formoterol Fumarate Dihydrate
- Where
- Germany
- Volunteers
- 4,034 people
- Sponsor
- Teva Pharma GmbH
Emergencies, Heart Failure
The Use of a Monitoring Device by General Practitioners During Out-of-hours Care
All calls that end up on the out-of-hours general practitioners' service (OHGPS), which contain a demand for an urgent home visit, are passed on to the on-call general practitioner (GP).
- Conditions
- Emergencies, Heart Failure, Pulmonary Embolism, Acute Exacerbation of Chronic Obstructive Pulmonary Disease
- Trial name
- NCT05222711
- Testing
- Use of the PICO(TM) monitoring device
- Where
- Belgium
- Volunteers
- 866 people
- Sponsor
- KU Leuven
IPF, Sarcoidosis
Nasal, Tracheal and Bronchial Mucosal Lining Fluid(MLF) Sampling From Patients With Respiratory Diseases
Nasal, tracheal and bronchial sampling of MLF in patients with idiopathic pulmonary fibrosis(IPF), sarcoidosis, tuberculosis(TB), asthma and COPD. Similar sampling from healthy controls for comparative data.
- Conditions
- IPF, Sarcoidosis, Tuberculosis, Asthma
- Trial name
- RESPI-SAM (NCT02807025)
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Bronchial Asthma, Bronchiectasis
The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease
Research is being conducted into chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD), asthma, interstitial lung disease, and bronchiectasis.
- Conditions
- Bronchial Asthma, Bronchiectasis, ILD, COPD
- Trial name
- NCT07060079
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University College, London
COPD Asthma, Asthma-COPD Overlap Syndrome
Evaluation of Inhalation Technique in Patients With COPD, Asthma or ACOS Using a Dry Powder Device (DPI)
This study analyzes the prevalence of patients using inhalation devices via incorrect technique and access the adherence of patients to correct inhalation technique when taught along with their subjective improvement of symptoms.
- Conditions
- COPD Asthma, Asthma-COPD Overlap Syndrome, Inhalation
- Trial name
- NCT03275935
- Where
- Nepal
- Volunteers
- 307 people
- Sponsor
- Kathmandu University School of Medical Sciences
Asthma
GSK2190915A - Bioavailability Study
GSK2190915 is a high affinity 5-lipoxygenase-activating protein (FLAP) inhibitor that reduces inflammation in cells. This study will evaluate three capsule and two tablet formulations to select the optimal formulation for further…
- Trial name
- NCT02224521
- Testing
- GSK2190915 Solution., GSK2190915 Granule Capsule (A), GSK2190915 Semi-solid Lipid Capsule (B)
- Where
- United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Obstructive Airway Diseases
Nasal Muco-ciliary Clearance Study With and Without Salt Inhalation
Investigating nasal muco-ciliary clearance by scintigraphy
- Trial name
- NCT04189016
- Testing
- Inhalation from a salt particle inhaler with or without content
- Where
- Denmark
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Liita Care ApS
Asthma COPD
Relationship Between Acoustic Breath Sounds and Spirometry
The goal of this clinical trial is to assess whether wheeze as assessed by a commercially available wheeze monitor is comparable to lung function as measured during a spirometry test.
- Trial name
- NCT06039943
- Testing
- Wheeze measurement
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University Hospital Birmingham
Pulmonary Disease, Chronic Obstructive, Asthma
Evaluation of the Respimat Inhaler vs. a HFA MDI Using Berodual in Patients With COPD With Poor MDI Technique.
The objective of this trial is to compare the total and regional deposition of aerosol in the lungs and oropharynx of patients with COPD and known poor MDI inhalation technique following inhalation of Berodual delivered via the…
- Trial name
- NCT00267917
- Testing
- Berodual Respimat, Berodual HFA-MDI
- Where
- Germany
- Volunteers
- 13 people
- Sponsor
- Boehringer Ingelheim
Cystic Fibrosis, Primary Ciliary Dyskinesia
Multiple Breath Washout, a Clinimetric Dataset
Monitoring patients with chronic, inflammatory airways disease particularly in the early stages is hampered by the relative insensitivity of current outcome measures to detect subtle changes.
- Conditions
- Cystic Fibrosis, Primary Ciliary Dyskinesia, Bronchiectasis, Asthma
- Trial name
- NCT03320382
- Testing
- Multiple breath washout testing
- Where
- United Kingdom
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Asthma, COPD Exacerbation
Study to Explore the Relationship Between the Level of Exhaled Breath Condensate Hydrogen Peroxide (EBC H2O2) as Measured Using a New Device Against Existing Measures of Lung Disease
A cross-sectional, observational study of EBC H2O2 levels, as measured by a novel device, 'Inflammacheck™', and other markers of disease severity and symptom control in patients with Asthma and COPD and volunteers with no history…
- Trial name
- EXHALE 1A (NCT04061291)
- Where
- United Kingdom
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Severe Asthma, COPD
K-HEALTH in AIR - Barcelona Pilot - Cohort
The study protocol is part of the European (EU) project "Knowledge for improving indoor AIR quality and HEALTH" (K-HEALTHinAIR, 2022-2026 - registry 101057693), which focuses on enhancing our understanding of how poor indoor air…
- Trial name
- NCT06421402
- Testing
- Air quality monitoring at patient's home, Questionnaires: Baseline & every six months, Lung function Testing: Baseline & every six months & during exacerbations
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Institut d'Investigacions Biomèdiques August Pi i Sunyer
Muscle Strength, Healthy
Reference Equations and Normative Data for Isometric Quadriceps and Handgrip Muscles STrength in Southern European Populations - RESTart: a Multicentre Study
This observational study aims to learn about peripheral muscle strength in healthy adults and people with chronic respiratory diseases.
- Conditions
- Muscle Strength, Healthy, Chronic Respiratory Diseases
- Trial name
- RESTart (NCT07628530)
- Where
- Spain
- Volunteers
- 2,815 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Asthma
"First-in-human" Study To Assess the Safety and Tolerability of PBF-680 in Male Healthy Volunteers
This is a phase I, single-center, randomized, double-blind, dose escalation study without therapeutic benefit, in which PBF-680 will be administered as single oral ascending dose to young male healthy volunteers.
- Trial name
- NCT01845181
- Testing
- PBF-680
- Where
- 2 sites in Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Obstructive Lung Disease, COPD
Inhalation Therapy in Ambulant and Hospitalized Patient Using Available Film Sequences From the Internet
There are different therapy strategies for patients suffering on obstructive lung disease like chronic obstructive pulmonary disease (COPD), and asthma bronchial available. One of these strategies includes inhalative drugs, e.g.
- Conditions
- Obstructive Lung Disease, COPD, Asthma
- Trial name
- InhaliPAD (NCT03087188)
- Testing
- Utilization of inhalator
- Where
- Germany
- Volunteers
- 114 people
- Sponsor
- RWTH Aachen University