Clinical trials: Asthma
Pulmonary Disease, Oropharyngeal Disease
Role of Helicobacter Pylori and Its Toxins in Lung and Digestive System Diseases
This study will examine bacteria and toxins in the mouth, lung and digestive system that may be the cause of various diseases or symptoms. H.
- Conditions
- Pulmonary Disease, Oropharyngeal Disease, Lymphangioleiomyomatosis, Pulmonary Fibrosis
- Trial name
- NCT00366509
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obstructive Sleep Apnea, Asthma
Effect of CPAP Treatment in Patients With Severe Uncontrolled Asthma: The ASTHMA-SLEEP Trial
The aim of the study is to evaluate the impact of CPAP treatment on asthma control in patients with severe uncontrolled asthma and obstructive sleep apnea (OSA)
- Trial name
- NCT06314477
- Testing
- CPAP treatment, Hygienic and dietary advice
- Where
- Spain
- Volunteers
- 138 people
- Sponsor
- Hospital Clinic of Barcelona
Asthma
A Clinical Study to Evaluate Symbicort Turbuhaler Used 'as Needed' in Adults and Adolescents With Asthma
The purpose of this study is to test if Symbicort (budesonide/formoterol) Turbuhaler is effective in treating asthma when used 'as needed' in patients with milder asthma.
- Trial name
- SYGMA2 (NCT02224157)
- Testing
- budesonode bid + terbutaline 'as needed'
- Where
- 340 sites in Australia, Brazil and 23 more
- Volunteers
- 4,215 people
- Sponsor
- AstraZeneca
Chronic Respiratory Disease
The Effect of an AEP on Patient's Knowledge Regarding Asthma Disease and Inhaler Technique: RCT
Asthma is an important chronic disease that causes a significant public health problem and the commonest medical conditions treated in health clinics giving rise to considerable morbidity and mortality.
- Trial name
- NCT02715219
- Testing
- Asthma Education Programme
- Volunteers
- 280 people
- Sponsor
- Clinical Research Centre, Malaysia
Asthma, Lung Diseases
Development and Evaluation of Community Asthma Program
To evaluate a community organization approach to promoting asthma management in four neighborhoods in St. Louis with predominantly low income, Black populations.
- Trial name
- NCT00005714
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Allergy
A Trial of Grazax in Subjects With Hayfever
The trial is performed to evaluate the efficacy and safety of specific immunotherapy with Grazax for treatment of grass pollen induced allergy.
- Trial name
- NCT00421655
- Testing
- Grazax
- Where
- United States
- Volunteers
- 329 people
- Sponsor
- ALK-Abelló A/S
Asthma, Smoking Cessation
Pediatric Emergency Department Decision Support System to Reduce Secondhand Smoke
This two phase study will develop and evaluate a Pediatric Emergency Department (PED) Decision Support System (DSS)-Electronic Medical Records (EMR) System to facilitate the identification of smokers and the delivery of a Second…
- Trial name
- NCT02489708
- Testing
- Cessation Counseling
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Acute Asthma Exacerbation
Acute Montelukast in Asthma
Patients presenting to hospital with an acute asthma exacerbation severe enough to require admission would receive full standard treatment according to British Thoracic Society guidelines in addition they would be offered the…
- Trial name
- AcMk (NCT01011452)
- Testing
- Montelukast
- Where
- United Kingdom
- Volunteers
- 87 people
- Sponsor
- University of East Anglia
Allergic Bronchial Asthma
c9,t11-CLA in Children and Adolescents With Allergic Asthma
The study was performed to investigate the effects of a dietary intervention with c9,t11-CLA on clinical and immunological parameters in children and adolescents with allergic bronchial asthma.
- Trial name
- NCT01026506
- Testing
- conjugated linoleic acid
- Where
- Germany
- Volunteers
- 29 people
- Sponsor
- University of Jena
Asthma
This Study Compared an in Home Asthma Management Program Provided by Nurses or Respiratory Therapist
This study compared an in-home asthma management program provided by nurses or respiratory therapists to see if those receiving program had fewer hospitalizations, clinic and emergency room visits and higher levels of…
- Trial name
- NCT00639847
- Testing
- In-home asthma management program (AMP) provided by nurses, In-home asthma management program (AMP) provided by respiratory therapists
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Allergic Asthma
A Study Evaluating the Persistency of Response With or Without Xolair (Omalizumab) After Long-term Therapy
This was a randomized, double-blind, placebo-controlled, 2-arm, 1-year study of participants who completed the EXCELS study (NCT00252135) and had received long-term treatment with Xolair.
- Trial name
- XPORT (NCT01125748)
- Testing
- Omalizumab, Asthma therapies
- Where
- 100 sites in United States
- Volunteers
- 176 people
- Sponsor
- Genentech, Inc.
Asthma
Examining Changes in Nasal IL-1 During Acute Asthma Exacerbation in Adolescents
To study the change from baseline in IL-1β (interleukin 1 beta) concentrations in the nasal airway during acute asthma exacerbation, specifically to measure the degree of change and identify the timing of peak IL-1β…
- Trial name
- Attack Asthma (NCT04748055)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Asthma, Rhinitis
Prevalence of Asthma and Rhinitis Symptoms Among Secondary School Students in Saudi Arabia
The purpose of this cross-sectional survey study is to describe the prevalence of asthma and Rhinitis symptoms among secondary school students in Saudi Arabia.
- Trial name
- NCT01085916
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz Medical City
Asthma
Glucagon-Like Peptide-1 Receptor Agonist in the Treatment of Adult, Obesity-related, Symptomatic Asthma (GATA-3)
This is a randomized placebo-controlled trial of semaglutide, an FDA-approved therapy for the treatment of type 2 diabetes mellitus and obesity, in adults with symptomatic asthma despite the use of inhaled steroids and with…
- Trial name
- GATA-3 (NCT05254314)
- Testing
- Semaglutide Pen Injector 2.4mg weekly
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Vanderbilt University Medical Center
Asthma, Lung Diseases
Center for Reducing Asthma Disparities - Rhode Island/Puerto Rico Centers
To reduce disparities in asthma among Latino children.
- Trial name
- NCT00281138
- Volunteers
- 983 people
- Sponsor
- Rhode Island Hospital
Allergic Asthma
A Study to Evaluate the Effect of Roflumilast on Airway Inflammation and Function Following Allergen Challenge in Subjects With Allergic Asthma
The study was a double-blind, placebo-controlled, crossover study to evaluate the efficacy of roflumilast on airway inflammation and function in patients with allergen-induced asthma.
- Trial name
- NCT01365533
- Testing
- Roflumilast
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- AstraZeneca
Asthma
Efficacy of QVAR vs Flovent Diskus on Small Airways in Poorly Controlled Asthmatic Adolescents/Adult Patients
The primary objective of this study is to evaluate the effect of Beclomethasone dipropionate HFA on small airways compared to Fluticasone propionate powder for inhalation administered twice daily to poorly controlled asthmatics.
- Trial name
- NCT00071552
- Testing
- Qvar, Flovent Diskus
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Asthma
Successful Control and Clinical Effectiveness Of SERETIDE(Salmeterol/Fluticasone Propionate) Study In Asthma.(SUCCESS)
The primary study objective is to demonstrate the clinical effectiveness of SERETIDE therapy compared to the current care in management of moderate to severe persistent asthma patients in Korea.
- Trial name
- NCT00480649
- Testing
- Salmeterol/ fluticasone propionate
- Where
- 12 sites in South Korea
- Volunteers
- 424 people
- Sponsor
- GlaxoSmithKline
Asthma
Sub-Sensitivity to Long-Acting Bronchodilators (LABA)
The purpose of this study is to look at whether Advair® and SYMBICORT® have different effects on airway constriction by means of methacholine challenge testing.
- Trial name
- NCT01117116
- Testing
- fluticasone propionate and salmeterol, budesonide and formoterol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Jewish Health
Lung Diseases, Asthma
Better Asthma Outcomes: Lowering Tobacco Smoke Exposure
To improve disease outcomes through reduction in secondhand tobacco smoke exposure of children with asthma
- Trial name
- NCT00217958
- Testing
- SHS reduction intervention based on social cognitive learning theory
- Sponsor
- Palo Alto Medical Foundation