Clinical trials: Asthma Attack
Asthma, Asthma Attack
The Effect of Asthma Flare-up Clinic After Exacerbation
The goal of this interventional study is to examine the effect of asthma flare-up clinic follow-up in adult subjects after an asthma flare-up. This study aim to answer the following questions: 1.
- Trial name
- NCT06201728
- Testing
- Follow-up in a flare-up clinic
- Where
- Israel
- Volunteers
- 230 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Acute Severe Asthma
Compare Efficacy Nebulized and Intravenous Magnesium Sulphate in Thai Children
The purpose of this study is to determine whether nebulized magnesium sulphate is effective in the treatment of acute severe asthma when comparison with intravenous magnesium sulphate
- Trial name
- NCT02112305
- Testing
- isotonic magnesium sulphate, 50% magnesium sulphate
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Queen Sirikit National Institute of Child Health
Asthma in Children
Reducing Asthma Attacks in Disadvantaged School Children With Asthma
Our UH3 clinical trial, "Reducing Asthma Attacks in Disadvantaged School Children with Asthma," seeks broad-scale implementation of our effective school-based approach to improve asthma disparities for children, ages 5-12 years…
- Trial name
- NCT06003569
- Testing
- BACK-S, BACK-E
- Where
- 13 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
Asthma Exacerbation
Effectiveness of the Aeroneb in Acute Severe Asthma
Background: The bronchodilator therapy is an essential component of the management of asthma exacerbation. The delivery of bronchodilators to the lungs in asthma exacerbations is usually achieved through nebulization (creating…
- Trial name
- NCT03029156
- Testing
- Aeroneb nebulizer, Small volume jet nebulizer
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Tufts Medical Center
Education, Medical
Repeated Versus Varied Simulation Scenarios to Teach Medical Students the Management of a Pediatric Asthma Exacerbation
Repeated exposure to simulated cases has been shown to improve performance, but repeating the same scenario may impair the ability of learners to transfer their knowledge and skills to slightly different situations.
- Trial name
- REVAR (NCT02754310)
- Testing
- Variation of scenarios, Repeated scenarios
- Where
- France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Ilumens
Asthma
REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment clinIcal remissioN, a prospEctive Study
This is a prospective, real-world, single arm, global, multi-centre study to evaluate the effect of timely treatment with mepolizumab (NUCALA) to achieve clinical remission in adult participants with severe asthma with an…
- Trial name
- REIMAGINE (NCT06041386)
- Testing
- Mepolizumab, Spirometry
- Where
- 65 sites in United States, Belgium and 7 more
- Volunteers
- 336 people
- Sponsor
- GlaxoSmithKline
Asthma
The Impact of Implementing a Nursing-driven Clinical Pathway for Inpatient Management of Children With Asthma
Asthma is the most common chronic disease of childhood and is responsible for large portion of pediatric admissions to Canadian hospitals.
- Trial name
- NAP (NCT02037841)
- Testing
- Nursing-driven clinical pathway for management of inpatient asthma
- Where
- Canada
- Volunteers
- 113 people
- Sponsor
- Children's Hospital of Eastern Ontario
Asthma, Asthma Attack
ASTHMAXcel Emergency Department Study
This protocol focuses on Phase 1 of a planned two-phase research project. Phase 1 aims to test and adapt a prototype ASTHMAXcelED application for the ED.
- Trial name
- ASTHMAXcel (NCT05013073)
- Testing
- ASTHMAXcel ED Application
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- Montefiore Medical Center
Asthma in Children, Asthma Attack
Child Asthma : What Parents Attitude During an Asthma Attack at Home Before Consulting the Pediatric Emergencies
prospective multicenter observational study. Parents whose children meet the inclusion criteria complete a questionnaire assessing the child's follow-up, the management of the current asthma attack, and the treatment provided at…
- Conditions
- Asthma in Children, Asthma Attack, Therapeutic Adherence
- Trial name
- ASPECT (NCT03967873)
- Where
- 2 sites in France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Brest
Persistent Asthma, Asthma in Children
Asthma Research in Children and Adolescents
The purpose of this study is to assess the evolution of disease control, health-related quality of life, and the risk of severe asthma exacerbations in children and adolescents with persistent asthma in Spain at short, mid and…
- Conditions
- Persistent Asthma, Asthma in Children, Asthma Exacerbation
- Trial name
- ARCA (NCT04480242)
- Testing
- Inhaled Corticosteroids (ICs), Fixed-Dose Combination of Inhaled Corticosteroids and Long- Acting Beta-agonist (ICs/LABA), Other treatments
- Where
- 15 sites in Spain
- Volunteers
- 525 people
- Sponsor
- Parc de Salut Mar
Asthma
A Study to Test if a Fixed-Dose Combination of Fluticasone Propionate/Albuterol Sulfate is Effective in Preventing Asthma Exacerbations
The primary objective of the study is to assess the efficacy of high dose fluticasone propionate (Fp)/albuterol sulfate (ABS) integrated electronic module multidose dry powder inhaler (eMDPI) compared to ABS eMDPI in decreasing…
- Trial name
- NCT06052267
- Testing
- TEV-56248, Albuterol sulfate
- Where
- 393 sites in United States, Argentina and 20 more
- Volunteers
- 2,772 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D LLC
Asthma
Pharmacodynamics, Safety, Tolerability, and Pharmacokinetics of Two Orally Inhaled Indacaterol Salts in Adult Subjects With Asthma.
This study is a randomized, double-blind, placebo-controlled, three-period cross-over study in approximately 54 subjects with asthma.
- Trial name
- NCT03257995
- Testing
- Indacaterol maleate, Indacaterol acetate
- Where
- 6 sites in United States
- Volunteers
- 54 people
- Sponsor
- Novartis Pharmaceuticals
Asthma
Mechanisms of Acute Asthma Exacerbations Through Molecular Analysis of Airway Secretions and Tissues
The purpose of this study is to investigate mechanisms which cause acute asthma exacerbations by examining blood and airway secretions during an acute onset (sputum or tracheal aspirates).
- Trial name
- MAST-X (NCT00603629)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of California, San Francisco
Asthma
The Predictors for Asthma Control by Stepwise Treatment During 6 Months in Korean Elderly
The Predictors for asthma control by stepwise treatment during 6 months in Korean elderly
- Trial name
- Prelude (NCT01370577)
- Where
- 5 sites in South Korea
- Volunteers
- 297 people
- Sponsor
- AstraZeneca
Childhood Asthma With Acute Exacerbation
Azithromycin Treatment of Hospitalized Children With Asthmatic Symptoms
The purpose of this double-blind, randomized, controlled clinical trial is to investigate the effect of a three-day azithromycin treatment versus placebo treatment in children aged 1-5 years who are hospitalized due to…
- Trial name
- COPSACazt (NCT05028153)
- Testing
- Azithromycin Oral Liquid Product
- Where
- Denmark
- Volunteers
- 320 people
- Sponsor
- Copenhagen Studies on Asthma in Childhood
Asthma
MK0476 Study in Adult Patients With Acute Asthma (0476-322)
This study evaluates the efficacy and safety of MK0476 intravenous administration in adult patients with acute asthma.
- Trial name
- NCT00229970
- Testing
- montelukast sodium
- Volunteers
- 225 people
- Sponsor
- Organon and Co
Asthma
Use of Dexamethasone in Pediatric Asthma Exacerbations
The purpose of this study is to compare the efficacy of a single dose of dexamethasone vs. two doses of dexamethasone in mild and moderate asthma exacerbations pediatric patients.
- Trial name
- NCT02192827
- Testing
- Dexamethasone Sodium Phosphate Injection
- Where
- United States
- Volunteers
- 318 people
- Sponsor
- University at Buffalo
Asthma Acute
Asthma Breath Biomarker Assessment
This study aims to assess the feasibility of capturing data on exhaled breath compounds during an acute asthma exacerbation. In addition to assessing the feasibility of such a study the investigators will collect data on…
- Trial name
- ABBA (NCT03084016)
- Where
- United Kingdom
- Volunteers
- 84 people
- Sponsor
- University of East Anglia
Asthma
Effect of Budesonide / Formoterol Combination in Repeated AMP Provocations
The aim is to study whether the budesonide component within the budesonide/ formoterol combination inhaler has additive value in a model of "slow onset acute asthma" , namely three AMP provocation tests performed on one day
- Trial name
- NCT00272753
- Testing
- budesonide/formoterol Turbuhaler, formoterol Turbuhaler, salbutamol
- Where
- 2 sites in Netherlands
- Volunteers
- 20 people
- Sponsor
- AstraZeneca
Asthmatic Attack
Asthma Inpatient Research on Education
Children with asthma are admitted for asthma attacks very frequently in the U.S. The families and children are given basic education about asthma but studies are needed to improve this education so that it makes a meaningful…
- Trial name
- AIREd (NCT02948738)
- Testing
- Interactive Asthma Education, Standard Asthma Education
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago